The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
Sex differences in obesity and the regulation of energy homeostasis
Abstract
Summary: Obesity prevalence is generally higher in women than in men, and there is also a sex difference in body fat distribution. Sex differences in obesity can be explained in part by the influence of gonadal steroids on body composition and appetite; however, behavioural, socio‐cultural and chromosomal factors may also play a role. This review, which evolved from the 2008 Stock Conference on sex differences in obesity, summarizes current research and recommendations related to hormonal and neuroendocrine influences on energy balance and fat distribution. A number of important gaps in the research are identified, including a need for more studies on chromosomal sex effects on energy balance, the role of socio‐cultural (i.e. gender) factors in obesity and the potential deleterious effects of high‐fat diets during pregnancy on the foetus. Furthermore, there is a paucity of clinical trials examining sex‐specific approaches and outcomes of obesity treatment (lifestyle‐based or pharmacological), and research is urgently needed to determine whether current weight loss programmes, largely developed and tested on women, are appropriate for men. Last, it is important that both animal and clinical research on obesity be designed and analysed in such a way that data can be separately examined in both men and women.
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Background
Cited by
Sex and Gender Differences in Risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus
Kautzky-Willer, A., Harreiter, J., & Pacini, G. (2016) · Endocrine Reviews · doi:10.1210/er.2015-1137 · Cited by 2,043
Body Fat Distribution, Incident Cardiovascular Disease, Cancer, and All-Cause Mortality
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The Prevalence of Food Addiction as Assessed by the Yale Food Addiction Scale: A Systematic Review
Pursey, K., Stanwell, P., Gearhardt, A., Collins, C., & Burrows, T. (2014) · Nutrients · doi:10.3390/nu6104552 · Cited by 537
The Association of Obesity and Cardiometabolic Traits With Incident HFpEF and HFrEF
Savji, N., Meijers, W. C., Bartz, T. M., Bhambhani, V., Cushman, M., Nayor, M., Kizer, J. R., Sarma, A., Blaha, M. J., Gansevoort, R. T., et al. (2018) · JACC: Heart Failure · doi:10.1016/j.jchf.2018.05.018 · Cited by 499
Male Inclusion in Randomized Controlled Trials of Lifestyle Weight Loss Interventions
Pagoto, S. L., Schneider, K. L., Oleski, J. L., Luciani, J. M., Bodenlos, J. S., & Whited, M. C. (2012) · Obesity · doi:10.1038/oby.2011.140 · Cited by 388
Metadata
- Authors
- Lovejoy, J. C., Sainsbury, A., & the Stock Conference 2008 Working Group
- Venue
- Obesity Reviews
- Publisher
- Wiley
- Published
- 2009-02-23
- Volume
- 10
- Issue
- 2
- Pages
- 154-167
- ISSN
- 1467-7881 (ISSN-L)
- 1467-789X
- OpenAlex
- W2137919415
- Cited by
- 421
- References
- 22
- FWCI
- 8.44
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
