The DOI matches its Crossref record.
INHIBITION OF THE PULSATILE SECRETION OF GROWTH HORMONE BY MONOCLONAL ANTIBODIES TO THE HYPOTHALAMIC GROWTH HORMONE RELEASING FACTOR (GRF)
Abstract
Infusion over 1 hour of a monoclonal antibody specific for rat hypothaiamic growth hormone releasing factor CGRF) abruptly abolishes the pulsatile secretion of growth hormone (GH) in normal nonrestrained rats. Resumption of the pulsatile secretion of GH occurs 2 to 3 days later. The episodic pulses of GH secretion thus appear to be due to a positive drive by hypothai amic GRF rather than to a periodic removal of the inhibitory activity of somatostatin.
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Citations
Cited by
Plotsky, P. M., & Vale, W. (1985) · Science · doi:10.1126/science.2864742 · Cited by 538
Ho, K. Y., Veldhuis, J. D., Johnson, M. L., Furlanetto, R., Evans, W. S., Alberti, K. G., & Thorner, M. O. (1988) · Journal of Clinical Investigation · doi:10.1172/jci113450 · Cited by 503
Frohman, L. A., Downs, T. R., Clarke, I. J., & Thomas, G. B. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114681 · Cited by 178
Metadata
- Authors
- Wehrenberg, W. B., Brazea, P., Luben, R., Bŏhlen, P., & Guillemin, R.
- Venue
- Endocrinology
- Publisher
- The Endocrine Society
- Published
- 1982-12
- Volume
- 111
- Issue
- 6
- Pages
- 2147-2148
- ISSN
- 0013-7227 (ISSN-L)
- 1945-7170
- OpenAlex
- W1970737866
- Cited by
- 197
- References
- 0
- FWCI
- 14.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- This page
- CoChat. (2026). Citation check: INHIBITION OF THE PULSATILE SECRETION OF GROWTH HORMONE BY MONOCLONAL ANTIBODIES TO THE HYPOTHALAMIC GROWTH HORMONE RELEASING FACTOR (GRF). https://app.cochat.ai/papers/10.1210/endo-111-6-2147
- The paper
- Wehrenberg, W. B., Brazea, P., Luben, R., Bŏhlen, P., & Guillemin, R. (1982). INHIBITION OF THE PULSATILE SECRETION OF GROWTH HORMONE BY MONOCLONAL ANTIBODIES TO THE HYPOTHALAMIC GROWTH HORMONE RELEASING FACTOR (GRF). Endocrinology. https://doi.org/10.1210/endo-111-6-2147
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
