17β-Estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-α.

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation.

Lacey, D. L., Timms, E., Tan, H.-L., Kelley, M. J., Dunstan, C. R., Burgess, T., Elliott, R., Colombero, A., Elliott, G., Scully, S., et al. (1998) · Cell · doi:10.1016/s0092-8674(00)81569-x · Cited by 5,439

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.

Simonet, W. S., Lacey, D. L., Dunstan, C. R., Kelley, M., Chang, M.-S., Lüthy, R., Nguyen, H. Q., Wooden, S., Bennett, L., Boone, T., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80209-3 · Cited by 5,130

Cloning of a novel receptor expressed in rat prostate and ovary.

Kuiper, G. G. J. M., Enmark, E., Pelto‐Huikko, M., Nilsson, S., & Gustafsson, J.-Α. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.12.5925 · Cited by 4,802

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

Yasuda, H., Shima, N., Nakagawa, N., Yamaguchi, K., Kinosaki, M., Mochizuki, S.-I., Tomoyasu, A., Yano, K., Goto, M., Murakami, A., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.7.3597 · Cited by 4,224

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph node organogenesis.

Kong, Y.-Y., Yoshida, H., Sarosi, I., Tan, H.-L., Timms, E., Capparelli, C., Morony, S., Oliveira-dos-Santos, A. J., Van, G., Itie, A., et al. (1999) · Nature · doi:10.1038/16852 · Cited by 3,351

Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.

Bucay, N., Sarosi, I., Dunstan, C. R., Morony, S., Tarpley, J., Capparelli, C., Scully, S., Tan, H. L., Xu, W., Lacey, D. L., et al. (1998) · Genes & Development · doi:10.1101/gad.12.9.1260 · Cited by 2,483

Modulation of Osteoclast Differentiation and Function by the New Members of the Tumor Necrosis Factor Receptor and Ligand Families

Suda, T., Takahashi, N., Udagawa, N., Jimi, E., Gillespie, M. T., & Martin, T. J. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.3.0367 · Cited by 2,345

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function.

Anderson, D. M., Maraskovsky, E., Billingsley, W. L., Dougall, W. C., Tometsko, M. E., Roux, E. R., Teepe, M. C., DuBose, R. F., Cosman, D., & Galibert, L. (1997) · Nature · doi:10.1038/36593 · Cited by 2,290

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.

Lubahn, D. B., Moyer, J. S., GOLDING, T. S., Couse, J. F., Korach, K. S., & Smithies, O. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.23.11162 · Cited by 1,902

The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene

Yoshida, H., Hayashi, S.-I., Kunisada, T., Ogawa, M., Nishikawa, S., Okamura, H., Sudo, T., Shultz, L. D., & Nishikawa, S.-I. (1990) · Nature · doi:10.1038/345442a0 · Cited by 1,789

Comparison of the effects of 17β-E2 and progesterone on the expression of osteoprotegerin in normal human osteoblast-like cells

Liao, E. Y., Luo, X., & Su, X. (2002) · Journal of Endocrinological Investigation · doi:10.1007/bf03345513 · Cited by 32

Estrogen inhibits vascular calcification in rats via hypoxia-induced factor-1α signaling

Wu, X., Zhao, Q., Chen, Z., Geng, Y., Zhang, W., Zhou, Q., Yang, W. P., Liu, Q., & Liu, H. (2020) · Vascular · doi:10.1177/1708538120904297 · Cited by 31

Osteoprotegerin-Receptor Activator of Nuclear Factor-κB Ligand Ratio: A New Approach to Osteoporosis Treatment?

Coetzee, M., & Kruger, M. C. (2004) · Southern Medical Journal · doi:10.1097/00007611-200405000-00018 · Cited by 31

Effects of alkylphenols on bone metabolism in vivo and in vitro

Hagiwara, H., Sugizaki, T., Tsukamoto, Y., Senoh, E., Goto, T., & Ishihara, Y. (2008) · Toxicology Letters · doi:10.1016/j.toxlet.2008.06.863 · Cited by 31

Estrogen enforces the integrity of blood vessels in the bone during pregnancy and menopause

Rodrigues, J., Wang, Y.-F., Singh, A., Hendriks, M., Dharmalingam, G., Cohen-Solal, M. E., Kusumbe, A. P., & Ramasamy, S. K. (2022) · Nature Cardiovascular Research · doi:10.1038/s44161-022-00139-0 · Cited by 29

ST2 regulates bone loss in a site‐dependent and estrogen‐dependent manner

Macari, S., Madeira, M. F. M., Lima, I. L. D. A., Pereira, T. S., Dias, G. J., Cirelli, J. A., de Molon, R. S., Fukada, S. Y., Szawka, R. E., Garlet, G. P., et al. (2018) · Journal of Cellular Biochemistry · doi:10.1002/jcb.27080 · Cited by 29

Puerarin concurrently stimulates osteoprotegerin and inhibits receptor activator of NF-κB ligand (RANKL) and interleukin-6 production in human osteoblastic MG-63 cells

Wang, Y., Yang, C., Xie, W. L., Zhao, Y. W., Li, Z. M., Sun, W. J., & Li, L. Z. (2014) · Phytomedicine · doi:10.1016/j.phymed.2014.04.012 · Cited by 26

Effects of 17β-estradiol on adiponectin regulation of the expression of osteoprotegerin and receptor activator of nuclear factor-κB ligand

Wang, Q.-P., Yang, L., Li, X., Xie, H., Liao, E.-Y., Wang, M., & Luo, X. (2012) · Bone · doi:10.1016/j.bone.2012.05.011 · Cited by 26

Estrogens and androgens inhibit association of RANKL with the pre‐osteoblast membrane through post‐translational mechanisms

Martin, A., Yu, J., Xiong, J., Khalid, A. B., Katzenellenbogen, B. S., Kim, S. H., Katzenellenbogen, J. A., Malaivijitnond, S., Gabet, Y., Krum, S. A., et al. (2017) · Journal of Cellular Physiology · doi:10.1002/jcp.25862 · Cited by 24

GH replacement therapy increases plasma osteoprotegerin levels in GH-deficient adults

Lanzi, R., Losa, M., Villa, I., Gatti, E., Sirtori, M., Fiume, C. D., & Rubinacci, A. (2003) · European Journal of Endocrinology · doi:10.1530/eje.0.1480185 · Cited by 23

Association of Serum Osteoprotegerin Levels with Bone Loss in Chronic Kidney Disease: Insights from the KNOW-CKD Study

Kim, C. S., Bae, E. H., Kwon, S., Han, S. H., Choi, K. H., Lee, J., Chae, D., Oh, K., Ahn, C., Kim, S. W., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0166792 · Cited by 22

TNFAIP3 Reduction-of-Function Drives Female Infertility and CNS Inflammation

Zammit, N. W., McDowell, J., Warren, J. A., Muskovic, W., Gamble, J., Shi, Y., Kaczorowski, D. C., Chan, C., Powell, J. E., Ormandy, C. J., et al. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.811525 · Cited by 21

Polymorphisms at the Osteoprotegerin and Interleukin-6 Genes in Relation to First-Ever Stroke

Strand, M., Söderström, I., Wiklund, P.-G., Hallmans, G., Weinehall, L., Söderberg, S., & Olsson, T. (2007) · Cerebrovascular Diseases · doi:10.1159/000108431 · Cited by 21

Direct and indirect effects of estrogen on osteoclasts.

Oursler, M. J. (2003) · PubMed · Cited by 21

Transgender bone health

Davidge-Pitts, C. J., & Clarke, B. L. (2019) · Maturitas · doi:10.1016/j.maturitas.2019.05.002 · Cited by 21

Serum osteoprotegerin concentrations are decreased in women with the polycystic ovary syndrome

Escobar-Morreale, H. F., Botella-Carretero, J. I., Martínez-García, M. Á., Luque‐Ramírez, M., Álvarez‐Blasco, F., & Millán, J. L. S. (2008) · European Journal of Endocrinology · doi:10.1530/eje-08-0107 · Cited by 21

Safety profiles of aromatase inhibitors and selective estrogen-receptor modulators in the treatment of early breast cancer

Yamamoto, Y., & Iwase, H. (2008) · International Journal of Clinical Oncology · doi:10.1007/s10147-008-0828-5 · Cited by 20

Comparison of the effects of genistein and zoledronic acid on the bone loss in OPG-deficient mice

Liu, J., Xu, K., Wen, G., Guo, H., San, L., Wu, X., Dai, R.-C., Sheng, Z., & Liao, E. (2008) · Bone · doi:10.1016/j.bone.2008.01.010 · Cited by 20

Analysis of the association of polymorphism in the osteoprotegerin gene with susceptibility to chronic kidney disease and periodontitis

Baioni, C. S., Souza, C. M., Braosi, A. P. R., Luczyszyn, S. M., da Silva, M. A. D., Ignácio, S. A., Machado, M. Â. N., Martins, W. D. B., RIELLA, M. C., Pecoits‐Filho, R., et al. (2008) · Journal of Periodontal Research · doi:10.1111/j.1600-0765.2008.01098.x · Cited by 19

Extra virgin olive oil in maternal diet increases osteogenic genes expression, but high amounts have deleterious effects on bones in mice offspring at adolescence.

Mousavi, S. N., Koohdani, F., Eslaminejad, M. B., Izadi, P., Eshraghian, M., Sayahpour, F. A., Neek, L. S., & Shidfar, F. (2016) · Europe PMC (PubMed Central) · doi:10.22038/ijbms.2016.7915 · Cited by 19

Osteoclast: Origin and Differentiation

Rubin, J. E., & Greenfield, E. M. (2005) · Springer eBooks · doi:10.1007/1-84628-016-8_1 · Cited by 18

Associations of Bone Mineral Density with RANKL and Osteoprotegerin in Arab Postmenopausal Women: A Cross-Sectional Study

Amer, O. E., Wani, K., Ansari, M. G. A., Alnaami, A. M., Aljohani, N., Abdi, S., Hussain, S. D., Al‐Daghri, N. M., & Alokail, M. S. (2022) · Medicina · doi:10.3390/medicina58080976 · Cited by 17

Effect of (-)-epigallocatechin-3-gallate in preventing bone loss in ovariectomized rats and possible mechanisms.

Song, D., Gan, M., Zou, J., Zhu, X., Shi, Q., Zhao, H., Luo, Z., Zhang, W., Li, S., Niu, J., et al. (2014) · Europe PMC (PubMed Central) · Cited by 17

Gene expression studies of osteoporosis: implications for microarray research

Dvornyk, V., Recker, R. R., & Deng, H. (2003) · Osteoporosis International · doi:10.1007/s00198-002-1373-0 · Cited by 17

Changes in the serum levels of osteoprotegerin and soluble receptor activator for nuclear factor κB ligand after estrogen-progestogen therapy and their relationships with changes in bone mass in postmenopausal women

Kim, J. G., Kim, J. H., Lee, D. O., Kim, H., Kim, J. Y., Suh, C. S., Kim, S. H., & Choi, Y. M. (2008) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e318133a153 · Cited by 16

Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency

Weitzmann, M. N., Roggia, C., Toraldo, G., Weitzmann, L., & Pacifici, R. (2002) · Journal of Clinical Investigation · doi:10.1172/jci200215687 · Cited by 16

Temporomandibular Joint Bone Tissue Resorption in Patients with Early Rheumatoid Arthritis Can Be Predicted by Joint Crepitus and Plasma Glutamate Level

Hajati, A., Näsström, K., Alstergren, P. J., Bratt, J., & Kopp, S. (2010) · Mediators of Inflammation · doi:10.1155/2010/627803 · Cited by 16

Oestrogen inhibits osteoclast formation induced by periodontal ligament fibroblasts

Wattanaroonwong, N., Schoenmaker, T., de Vries, T. J., & Everts, V. E. (2010) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2010.10.004 · Cited by 16

Verification of IL-17A and IL-17F in oral tissues and modulation of their expression pattern by steroid hormones

Konermann, A., Winter, J., Novak, N., Allam, J., & Jäger, A. (2013) · Cellular Immunology · doi:10.1016/j.cellimm.2013.10.004 · Cited by 15

Differentiation of skeletal osteogenic progenitor cells to osteoblasts with 3,4-diarylbenzopyran based amide derivatives: Novel osteogenic agents

Gupta, A. K., Ahmad, I., Kureel, J., John, A. A., Sultan, E., Chanda, D., Agarwal, N. K., Alauddin, Wahajuddin, M., Prabhaker, S., et al. (2016) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2016.05.023 · Cited by 14

17β-estradiol activates mTOR in chondrocytes by AKT-dependent and AKT-independent signaling pathways.

Tao, Y., Sun, H., Sun, H., Qiu, X., Xu, C., Shi, C., & Du, J. (2015) · PubMed Central · Cited by 13

LC, a novel estrone–rhein hybrid compound, concurrently stimulates osteoprotegerin and inhibits receptor activator of NF-κB ligand (RANKL) and interleukin-6 production by human osteoblastic cells

Wang, Y., Li, L. Z., Zhang, Y. L., Zhu, Y. Q., Wu, J., & Sun, W. J. (2011) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2011.01.018 · Cited by 13

Induction of targeted osteogenesis with 3-aryl-2H-benzopyrans and 3-aryl-3H-benzopyrans: Novel osteogenic agents

Gupta, A. K., Ahmad, I., Kureel, J., Hasanain, M., Pandey, P. K., Singh, S., John, A. A., Sarkar, J., & Singh, D. R. (2016) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2016.01.010 · Cited by 13

MARKERS OF BONE METABOLISM IN EUGONADAL FEMALE PATIENTS WITH β-THALASSEMIA MAJOR

Angelopoulos, N., Goula, A., Katounda, E., Rombopoulos, G., Kaltzidou, V., Kaltsas, D., Konstandelou, E., & Tolis, G. (2007) · Pediatric Hematology and Oncology · doi:10.1080/08880010701533611 · Cited by 13

Responses of Urinary N-Telopeptide and Renal Calcium Handling to PTH Infusion after Treatment with Estrogen, Raloxifene, and Tamoxifen

Kulak, C. A. M., Baz-Hecht, M., Nieves, J. W., Shen, V., Lindsay, R. S., & Cosman, F. (2012) · Calcified Tissue International · doi:10.1007/s00223-012-9572-y · Cited by 12

Bone marrow stromal cells express two distinct splice variants of ER‐α that are regulated by estrogen

Sanyal, A., Riggs, B. L., Spelsberg, T. C., & Khosla, S. (2004) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20291 · Cited by 12

Effects of Sideritis euboea (Lamiaceae) Aqueous Extract on IL-6, OPG and RANKL Secretion by Osteoblasts

Kassi, E. N., Paliogianni, A., Dontas, I. A., Aligiannis, N., Halabalaki, M., Papoutsi, Z., Skaltsounis, A., & Moutsatsou, P. (2011) · Natural Product Communications · doi:10.1177/1934578x1100601131 · Cited by 12

Polymorphisms of OPG and their relation to the mineral density of bones in pre- and postmenopausal women

Boroń, D., Kotrych, D., Bartkowiak-Wieczorek, J., Uzar, I., Bogacz, A., & Kamiński, A. (2015) · International Immunopharmacology · doi:10.1016/j.intimp.2015.07.015 · Cited by 11

Osteoclastogenesis from bone marrow cells during estrogen-induced medullary bone formation in Japanese quails

Hiyama, S., Yokoi, M., Akagi, Y., Kadoyama, Y., Nakamori, K., Tsuga, K., Uchida, T., & Terayama, R. (2019) · Journal of Molecular Histology · doi:10.1007/s10735-019-09835-x · Cited by 11

Hormone and receptor activator of NF-κB (RANK) pathway gene expression in plasma and mammographic breast density in postmenopausal women

Mintz, R. L., Wang, M., Xu, S., Colditz, G. A., Markovic, C., & Toriola, A. T. (2022) · Breast Cancer Research · doi:10.1186/s13058-022-01522-2 · Cited by 10

Comparison of maternal isocaloric high carbohydrate and high fat diets on osteogenic and adipogenic genes expression in adolescent mice offspring

Mousavi, S. N., Koohdani, F., Shidfar, F., & Eslaminejad, M. B. (2016) · Nutrition & Metabolism · doi:10.1186/s12986-016-0130-x · Cited by 10

Influence of Cortisol, Gonadal Steroids and an Energy Deficit on Biochemical Indicators of Bone Turnover in Swine

Weiler, U., Finsler, S., & Claus, R. (2003) · Zentralblatt für Veterinärmedizin Reihe A · doi:10.1046/j.1439-0442.2003.00493.x · Cited by 10

RANK/RANKL Signaling Pathway in Breast Development and Cancer

Pérez-Chacón, G., Santamarı́a, P. G., Redondo-Pedraza, J., & González‐Suárez, E. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-70875-6_16 · Cited by 9

Serum osteoprotegerin and soluble receptor activator of nuclear factor κB ligand levels in patients with a history of differentiated thyroid carcinoma: a case-controlled cohort study

Giusti, M., Cecoli, F., Fazzuoli, L., Franchis, V. D., Ceresola, E., Ferone, D., Mussap, M., & Minuto, F. M. (2007) · Metabolism · doi:10.1016/j.metabol.2007.01.004 · Cited by 9

Design and synthesis of 3-arylbenzopyran based non-steroidal vitamin-D 3 mimics as osteogenic agents

Ahmad, M. I., Raghuvanshi, D. S., Singh, S., John, A. A., Prakash, R., Nainawat, K. S., Singh, D. R., Tripathi, S., Sharma, A. K., & Gupta, A. K. (2016) · MedChemComm · doi:10.1039/c6md00469e · Cited by 9

A Randomized Placebo-Controlled Trial of Short-Term Graded Transdermal Estradiol in Healthy Gonadotropin-Releasing Hormone Agonist-Suppressed Pre- and Postmenopausal Women: Effects on Serum Markers of Bone Turnover, Insulin-Like Growth Factor-I, and Osteoclastogenic Mediators

Liu, P. Y., Hoey, K. A., Mielke, K. L., Veldhuis, J. D., & Khosla, S. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1583 · Cited by 9

Involvement of molecular mimicry between human T‐cell leukemia virus type 1 gp46 and osteoprotegerin in induction of hypercalcemia

Sagara, Y., Inoue, Y., Sagara, Y., & Kashiwagi, S. (2009) · Cancer Science · doi:10.1111/j.1349-7006.2008.01061.x · Cited by 9

The use of mucoadhesive oral patches containing epigallocatechin-3-gallate to treat periodontitis: an in vivo study

Lashari, D. M., Aljunaid, M., Lashari, Y., Qaid, H. R., Ridwаn, R. D., Diyatri, I., Kaid, N., & Alkadasi, B. A. (2022) · Journal of Taibah University Medical Sciences · doi:10.1016/j.jtumed.2022.06.006 · Cited by 8

Reproductive and Lifestyle Factors and Circulating sRANKL and OPG Concentrations in Women: Results from the EPIC Cohort

Sarink, D., Yang, J., Johnson, T., Chang-Claude, J. C., Overvad, K., Olsen, A., Tjønneland, A. M., Fournier, A., Mancini, F. R., Kvaskoff, M., et al. (2019) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-19-0241 · Cited by 8

Characterization of osteoblastic properties of 7F2 and UMR-106 cultures after acclimation to reduced levels of fetal bovine serum

Ganguly, S. S., Ashley, L. A., Pendleton, C., Grey, R., Howard, G. C., Castle, L., Peyton, D. K., Fultz, M. E., & DeMoss, D. (2008) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y08-055 · Cited by 7

Sex Steroid Effects on Bone Metabolism

Monroe, D. G., Spelsberg, T. C., & Khosla, S. (2006) · Elsevier eBooks · doi:10.1016/b978-012088562-6/50020-0 · Cited by 7

Bone mineral density and serum levels of estradiol and osteoprotegerin in postmenopausal women with viral cirrhosis☆

Gonzalez-Calvin, J. L., Mundi, J. L., Casado, F. J., & Olivares, E. G. (2004) · Gastroenterology · doi:10.1053/j.gastro.2004.02.047 · Cited by 7

Serum Osteoprotegerin and Sex Steroid Levels in Patients With Prostate Cancer

Varsavsky, M., Reyes‐García, R., Perez, M. D., Ramírez, A. R. G., Mijan, J. L., & Muñoz‐Torres, M. (2012) · Journal of Andrology · doi:10.2164/jandrol.111.014696 · Cited by 6

Prostaglandin F2α negatively regulates bone resorption in murine osteoclast development

Kamon, M., Fujita, D., Goto, N., Amano, H., & Sakamoto, K. (2008) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2008.06.002 · Cited by 6

Does estrogen play a role in response to adjuvant bone-targeted therapies?

Russell, K., Amir, E., Paterson, A. H. G., Josse, R. G., Addison, C., Kuchuk, I., & Clemons, M. J. (2013) · Journal of bone oncology · doi:10.1016/j.jbo.2013.06.001 · Cited by 6

Gonadal Hormones and Bone

Yoshida, T., Wang, J., & Stern, P. H. (2019) · Handbook of experimental pharmacology · doi:10.1007/164_2019_327 · Cited by 6

Delineating the role of osteoprotegerin as a marker of breast cancer risk among women with a BRCA1 mutation

Park, S. S., Uzelac, A., & Kotsopoulos, J. (2022) · Hereditary Cancer in Clinical Practice · doi:10.1186/s13053-022-00223-3 · Cited by 5

PCE17 and its active compounds exert an anti-osteoporotic effect through the regulation of receptor activator of nuclear factor-κB ligand in ovariectomized mice

Jeong, H., Kim, M. H., Kim, H.-J., Kim, H.-Y., Nam, S., Han, N., Lee, B., Cho, H., Moon, P., & Kim, H. (2018) · Journal of Food Biochemistry · doi:10.1111/jfbc.12561 · Cited by 4

The Role of the Immune System in the Development of Osteoporosis

Mödder, U. I., Riggs, B. L., & Khosla, S. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-375670-1.10009-3 · Cited by 4

Osteoporosis: Pathophysiology and Clinical Aspects

Mikosch, P. (2011) · Springer eBooks · doi:10.1007/978-3-7091-0520-7_7 · Cited by 3

Influence of sex and estrogen on vitamin D‐induced arterial calcification in rats

Nakamura, T., Akishita, M., Kozaki, K., Toba, K., Orimo, H., & Ouchi, Y. (2003) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1046/j.1444-1586.2003.00077.x · Cited by 3

Basic Aspects of Osteoclast Differentiation and Function

Alesi, N., Charles, J. F., & Nakamura, M. C. (2020) · Contemporary Endocrinology · doi:10.1007/978-3-319-69287-6_2 · Cited by 3

Employment of selective pharmacologically active natural compounds in treatment and management of osteoporosis

Upmanyu, V., Sapra, L., & Srivastava, R. K. (2022) · Studies in natural products chemistry · doi:10.1016/b978-0-323-91250-1.00005-7 · Cited by 2

Die Rolle von RANK-Ligand und Osteoprotegerin bei Osteoporose

Hofbauer, L. C. (2004) · Journal für Kardiologie (Krause & Pachernegg GmbH) · Cited by 2

The Current Knowledge of Genetic Susceptibility Influencing Dental Implant Outcomes

Alvim‐Pereira, F., Cristina, C., & Cristina, P. (2011) · InTech eBooks · doi:10.5772/18065 · Cited by 1

Differential effects of arachidonic acid and docosahexaenoic acid on cell biology and osteoprotegerin synthesis in osteoblast-like cells

Coetzee, M. (2006) · UpSpace Institutional Repository (University of Pretoria) · Cited by 1

Differentially load-regulated gene expression in mouse trabecular osteocytes

Wasserman, E. (2010) · Repository for Publications and Research Data (ETH Zurich) · doi:10.3929/ethz-a-006128911 · Cited by 1

The interrelationship of sex steroid levels, body composition and bone characteristics in men

Lapauw, B. (2009) · Ghent University Academic Bibliography (Ghent University)

Bedeutung von RANK-Ligand und Osteoprotegerin für den Knochenstoffwechsel

Hofbauer, L. C., & Schoppet, M. (2006) · Springer eBooks · doi:10.1007/3-540-28782-5_21

An Agent-based Model for Evaluating Cellular Mechanisms of Bone Remodeling

Schutte, L. (2012) · KiltHub Repository · doi:10.1184/r1/6714668

RANKL, RANK, and OPG

Kong, Y., & Penninger, J. M. (2003) · doi:10.1007/978-1-59259-405-4_23

The Effect of Phytoestrogens on Bone and T Cells Differentiation and Activity

Karieb, S. S. (2012) · PEARL (University of Plymouth) · doi:10.24382/1814

Gene expression analysis of metabolic markers during bone regeneration in a rat model

Kasch, C., Osterberg, A., Granitzka, T., Lindner, T., Haenle, M., Bader, R., Skripitz, R., & Jonitz‐Heincke, A. (2014) · Osteologie/Osteology · doi:10.1055/s-0037-1620051

Androgens, Skeletal Homeostasis, and Osteoporosis

Vanderschueren, D., Vandenput, L., Verstuyf, A., Swinnen, J. V., Bouillon, R., & Boonen, S. (2002) · Springer eBooks · doi:10.1007/978-1-4615-1161-8_16

Glutamate modulates temporomandibular joint bone tissue resorption in patients with early rheumatoid arthritis

Hajati, A. (2010) · Figshare

Ciblage thérapeutique des tumeurs osseuses primitives par transfert de gène

Lamoureux, F. (2008) · OpenGrey (Institut de l'Information Scientifique et Technique)

Add-backs to prevent skeletal fragility: foresight or folly?

Rosen, C. J. (2002) · Menopause The Journal of The North American Menopause Society · doi:10.1097/00042192-200207000-00002

Osteogenic Response of Human Osteoblasts Derived from Mandible and Maxilla: A Preliminary Study

Yang, H. J., Song, Y. M., Kim, R. Y., Oh, J. H., Cho, T. H., Kim, I. S., & Hwang, S. J. (2013) · The Journal Of Korean Association of Maxillofacial Plastic and Reconstructive Surgeons · doi:10.14402/jkamprs.2013.35.1.031

Cancer treatment‐induced bone loss: A review

Barnett, F. S., & BOER, R. D. (2006) · Asia-Pacific Journal of Clinical Oncology · doi:10.1111/j.1743-7563.2006.00067.x

Effects of soybean isoflavones on expression levels of osteoprotegerin and osteoprotegerin ligand mRNAs in bone tissues of ovariectomized rats

Wang, Q. (2006) · Journal of Chinese Integrative Medicine · doi:10.3736/jcim20060317

Συσχέτιση μεταξύ οστεοπόρωσης και περιοδοντίτιδας Association between osteoporosis and periodontitis

Dereka, X. E. (2009)

Muscular Strength Training Modifies Regulation of Bone Remodeling: Inferences from Serum Biomarkers in Young Women

Mardock, M. A. (2003) · VTechWorks (Virginia Tech)

Mecanismos de calcificación vascular asociados a la uremia y al tratamiento con Calcitriol.

García, S. (2009) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)

EFFETS DES LIPOPROTÉINES DE FAIBLE DENSITÉ OXYDÉES SUR LES CELLULES OSTÉOBLASTIQUES

Chimie, D. D. (2008)

Elucidating Differences in Osteoclast Activation Mechanisms: Looking for Targets to Prevent Pathological Bone Resorption

Trebec‐Reynolds, D. P. (2010) · TSpace (University of Toronto)

Pathogenesis of Inflammation-Induced Bone Loss

Humphrey, M. B., & Nakamura, M. C. (2006) · Elsevier eBooks · doi:10.1016/b978-0-323-03437-1.50032-4

Bones and Rheumatology

Abdulkhaliq, A. A. (2021) · Springer eBooks · doi:10.1007/978-981-15-8323-0_10

The Effects of TGF-ß3, 17-ß Estradiol and Bisphenol A on Osteoprotegerin Production in Osteoblasts

DİKMEN, T. (2021) · Kocatepe Veterinary Journal · doi:10.30607/kvj.889086

Classificação e fisiopatologia da osteoporose

Lopes, J. B., & Pereira, R. M. R. (2012) · Revista Paulista de Reumatologia · doi:10.46833/reumatologiasp.2011.10.s1.21-29

Osteoporosis: Pathophysiology and Clinical Aspects

Mikosch, P. (2016) · Springer eBooks · doi:10.1007/978-3-319-34238-2_7

Astaxanthin Attenuates Nonalcoholic Steatohepatitis with Downregulation of Osteoprotegerin in Ovariectomized Mice Fed Choline-Deficient High-Fat Diet

Zhao, M., Ma, L., Honda, T., Kato, A., Ohshiro, T., Yokoyama, S., Yamamoto, K., Ito, T., Imai, N., Ishizu, Y., et al. (2022) · Digestive Diseases and Sciences · doi:10.1007/s10620-022-07489-6

Rôle du récepteur RANK dans la régulation du métabolisme énergétique hépatique et adipocytaire

Phan, F. (2022) · theses.fr (ABES) · doi:10.70675/009ba81az6addz47b3z9e33zcc6ad1543dcb

The Role of Androgens and Estrogens in the Male Skeleton

Khosla, S., & Bilezikian, J. P. (2004) · Principles of Gender-Specific Medicine · doi:10.1016/b978-012440905-7/50368-6

Additional file 1 of Hormone and receptor activator of NF-κB (RANK) pathway gene expression in plasma and mammographic breast density in postmenopausal women

Mintz, R., Wang, M., Xu, S., Colditz, G. A., Markovic, C., & Toriola, A. T. (2022) · Figshare · doi:10.6084/m9.figshare.19603441

Effects of Morinda citrifolia L. leaf aqueous extract on fatigue and bone health

Mohamad Shalan, N. A. A. (2015) · Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)

Osteoclast differentiation by Pasteurella multocida toxin

Strack, J. (2014) · FreiDok plus (Universitätsbibliothek Freiburg)

Homéogènes Dlx, signalisation RANK/RANKL et ostéosarcomes

Navet, B. (2016) · theses.fr (ABES) · doi:10.70675/9f9d3d45zb9e6z496dz8aa6z8b9e2722f757

“One-stop-shop” medical imaging for osteoporosis and obese patients: a narrative review

Zhang, L., Lei, H., Li, Y., Yang, H., & Zhao, H. (2026) · Journal of Endocrinological Investigation · doi:10.1007/s40618-026-02810-w

Bavachin Mitigates Bone Loss via RANKL Inhibition and Runx2 Activation in a Rat Model of Post-menopausal Osteoporosis

Shang, C., Song, J., & 李効松 (2026) · Pharmacognosy Magazine · doi:10.1177/09731296261447606

Development and Validation of a Multivariable Prediction Model for Recurrent Osteoporotic Fractures in Elderly Patients With Type 2 Diabetes Mellitus: A Prospective Observational Study

Shi, W., Sapbamrer, R., Liang, D., Pang, G., Tang, W., Liu, Y., & Ma, X. (2026) · Journal of Osteoporosis · doi:10.1155/joos/6991780

17β-Estradiol Stimulates Expression of Osteoprotegrin(OPG)by a Mouse Stromal Cell Line,ST-2,via Estrogen Receptor-α

斎賀, 美. (2001) · doi:10.11501/3180922

Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells.

Hofbauer, L. C., Khosla, S., Dunstan, C. R., Lacey, D. L., Spelsberg, T. C., & Riggs, B. L. (1999) · Endocrinology · doi:10.1210/endo.140.9.7131 · Cited by 692

The effects of estrogen on osteoprotegerin, RANKL, and estrogen receptor expression in human osteoblasts.

Bord, S., Ireland, D. C., Beavan, S. R., & Compston, J. E. (2003) · Bone · doi:10.1016/s8756-3282(02)00953-5 · Cited by 333

Comparison of the effects of 17β-E2 and progesterone on the expression of osteoprotegerin in normal human osteoblast-like cells

Liao, E. Y., Luo, X., & Su, X. (2002) · Journal of Endocrinological Investigation · doi:10.1007/bf03345513 · Cited by 32

Effect of 17#beta#-estradiol (E_(2)) on the gene expression of osteoprotegerin in human osteoblast and MG-63 cells.

Yuan, L., Hode, Z., Deng, X., Zhang, X., Jian, P., & Xianpeng, W. (2001) · Zhonghua neifenmi daixie zazhi