Treatment with Flutamide, Metformin, and Their Combination Added to a Hypocaloric Diet in Overweight-Obese Women with Polycystic Ovary Syndrome: A Randomized, 12-Month, Placebo-Controlled Study
Gambineri, Alessandra, Patton, Laura, Vaccina, Antonella, Cacciari, Mauro, Morselli-Labate, Antonio Maria, Cavazza, Carla, Pagotto, Uberto, Pasquali, Renato·2006·The Journal of Clinical Endocrinology & Metabolism
Cited by (221)
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- Effectiveness of long-term (twelve months) nonsurgical weight loss interventions for obese women with polycystic ovary syndrome: a systematic reviewFiona Nicholson · 2010 · International Journal of Women s Health
- Comparison of Finasteride, Metformin, and Finasteride Plus Metformin in PCOSHalit Diri · 2017 · Acta Endocrinologica (Bucharest)
- Effects of Low-Dose Spironolactone Combined with Metformin or Either Drug Alone on Insulin Resistance in Patients with Polycystic Ovary Syndrome: A Pilot StudyTao Long, Ying Zhang, Chun‐Ping Zeng, Siyuan Zheng, Lin Zhou, Haiyan Liu · 2022 · International Journal of Endocrinology
- Fatty acid-binding protein-4 plasma levels are associated to metabolic abnormalities and response to therapy in girls and young women with androgen excessIolanda Lázaro, Marta Díaz, Anna Cabré, L. Masana, Lourdes Ibáñez · 2011 · Gynecological Endocrinology
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- The Role of Androgen Excess in Metabolic Dysfunction in WomenHéctor Francisco Escobar-Morreale · 2017 · Advances in experimental medicine and biology
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- Metformin and polycystic ovary syndromeTessa G Lebinger · 2007 · Current Opinion in Endocrinology Diabetes and Obesity
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- Committee Opinion No. 714: Obesity in Adolescents2017 · Obstetrics and Gynecology
- Flutamide–metformin for post-menarcheal girls with preclinical ovarian androgen excess: evidence for differential response by androgen receptor genotypeKen K. Ong, Francis de Zegher, Abel López‐Bermejo, David B. Dunger, Lourdes Ibáñez · 2007 · European Journal of Endocrinology
- The American Diabetes Association's 57th Annual Advanced Postgraduate CourseZachary T. Bloomgarden · 2010 · Diabetes Care
- A safety evaluation of current medications for adult women with the polycystic ovarian syndrome not pursuing pregnancyManuel Luque‐Ramírez, A.E. Ortiz-Flores, Lía Nattero‐Chávez, Héctor Francisco Escobar-Morreale · 2020 · Expert Opinion on Drug Safety
- Age-Dependent Changes in the Effects of Androgens on Female Metabolic and Body Weight Regulation Systems in Humans and Laboratory AnimalsTakeshi Iwasa, Hiroki Noguchi, Risa Tanano, Erika Yamanaka, Asuka Takeda, Kou Tamura, Hidenori Aoki, Tatsuro Sugimoto, Hikari Sasada, Takaaki Maeda et al. · 2023 · International Journal of Molecular Sciences
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- Aspects of Cardiometabolic Risk in Women with Polycystic Ovary SyndromeThomas Paterakis, Evanthia Diamanti‐Kandarakis · 2014 · Current Obesity Reports
- Low-dose flutamide for women with androgen excess: Anti-androgenic efficacy and hepatic safetyFrancis de Zegher, Lourdes Ibáñez · 2009 · Journal of Endocrinological Investigation
- Role of the AMP-Activated Protein Kinase in the Pathogenesis of Polycystic Ovary SyndromeAbduldaheem Turki Jalil, Mahdi Abd Zair, Zainab Rahi Hanthal, Sarmad Jaafar Naser, Tahani Aslandook, Munther Abosaooda, Ali A. Fadhil · 2023 · Indian Journal of Clinical Biochemistry
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- Polycystic ovary syndrome (PCOS): metformin.David J Cahill, Katherine O’Flynn O’Brien · 2015 · Europe PMC (PubMed Central)
- Management of cardiometabolic complications in polycystic ovary syndrome: Unmet needsLicy L. Yanes Cardozo, Damián G. Romero · 2021 · The FASEB Journal
- Agaricus Subrufescens ameliorates ovarian dysfunction and regulates altered biochemical parameters in rats with Letrozole induced polycystic ovarian syndromeSarad Pawar Naik Bukke, Bharghava Bhushan Rao Pathange, Srikanth Kumar Karumanchi, Jalaiah Marri, Revathi Boyina, Kavya Rachamsetty, Bhargavi Manchikalapati, Saidi Odoma, Hussaini Bello · 2023 · Journal of Ovarian Research
- Adrenal Androgen Predictive Effects on Clinical and Metabolic Abnormalities of Polycystic Ovary SyndromeSebastião Freitas de Medeiros, Bruna Barcelo Barbosa, Matheus Antônio Souto de Medeiros, Ana Karine Lin Winck Yamamoto, Márcia Marly Winck Yamamoto · 2022 · Revista Brasileira Ginecologia e Obstetrícia
- Conceptual Biology Research Supporting Platform: Current Design and Future DirectionsYing Xie, Jayasimha R. Katukuri, Vijay V. Raghavan, Tony Presti · 2008 · Studies in computational intelligence
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- Sex hormones, obesity and type 2 diabetes-is there a link?Alessandra Gambineri · 2018 · Endocrine Abstracts
- Effects of weight loss on testosterone, sex hormone‐binding globulin, adiposity, and insulin sensitivity in women and menJustine M. Mucinski, David E. Kelley, Stephen J. Winters, Bret H. Goodpaster · 2025 · Obesity
- Effects of placebo‐controlled insulin‐sensitizing drugs on hormonal parameters in polycystic ovary syndrome patients: A network meta‐analysisRong Huang, Peng‐Fei Zhao, Jianhua Xu, Dongdong Liu, Fudong Luo, Yong‐Hui Dai · 2017 · Journal of Cellular Biochemistry
- Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-AnalysisTina Kaur Thethi, Bonnie Katalenich, Prathima Nagireddy, Pankdeep Chabbra, Nitesh D Kuhadiya, Vivian Andrew Fonseca · 2015 · Endocrine Practice
- Metformin does not improve insulin sensitivity over hypocaloric diets in women with polycystic ovary syndrome: a systematic review of 12 studiesSamantha Celeste Garcia-Hernandez, Leonardo M. Porchia, Blanca T. Pacheco-Soto, Esther López‐Bayghen, M. Elba González-Mejía · 2021 · Gynecological Endocrinology
- Hyperandrogenism, Hirsutism, and Polycystic Ovary SyndromeRandall B. Barnes, David A. Ehrmann, Robert L. Rosenfield · 2010 · Elsevier eBooks
- Androgen actions in metabolic tissues in polycystic ovary syndromeCaitlin L. MacRae, Rebecca E. Campbell · 2026 · Endocrinology
- Diabetes advice for women with polycystic ovary syndrome: prevention, prevention, preventionHamidreza Mani, Kamlesh Khunti, Miles J Levy, Melanie Jane Davies · 2013 · Diabetes Management
- The effects of androgens on metabolic functions in femalesTakeshi Iwasa, Yuri Yamamoto, Akari Shinya, Saki Minato, Rie Yanagihara, Shuhei Kamada, Junki Imaizumi, Tomohiro Kagawa, Aya Shirakawa, Hiroki Noguchi et al. · 2021 · The Journal of Medical Investigation
- Efficacy of Weight‐Lowering Agents on Fat Distribution: A Systematic Review and Network Meta‐Analysis of Randomized Controlled TrialsXiuqi Qiao, Weihao Wang, Jiaming Cao, Lixin Guo, Qi Pan · 2026 · Obesity Reviews
- Impact of pharmacological interventions on biochemical hyperandrogenemia in women with polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trialsMohammed Altigani Abdalla, Najeeb Zaheer Shah, Harshal Deshmukh, Amirhossein Sahebkar, Linda Östlundh, Rami H. Al‐Rifai, Stephen Lawrence Atkin, Thozhukat Sathyapalan · 2022 · Archives of Gynecology and Obstetrics
- The Endocrinological Basis for Polycystic Ovary Syndrome: An Evolutionary PerspectiveDaniel Anthony Dumesic, Bernard J. Crespi, Vasantha Padmanabhan, David Howard Abbott · 2025 · Endocrinology
- Intrinsic abnormalities of adipose tissue and adipose tissue dysfunction in PCOSPoli Mara Spritzer, Betânia Rodrigues dos Santos, Tayane Muniz Fighera, Lucas Bandeira Marchesan, Sheila Bünecker Lecke · 2021 · Elsevier eBooks
- Cardiovascular Health in Women—Across the LifespanJaya Chandrasekhar, Jessica Victoria Yao, Simone Gong, Pasangi Madhuka Wijayarathne, Monique Watts, Swati Mukherjee · 2025 · Clinical Endocrinology
- The polycystic ovary syndrome: a position statement from the European Society ofGerard S. Conway, Didier Dewailly, Evanthia Diamanti‐Kandarakis, Stephen Franks, Alessandra Gambineri, Fahrettin Keleştimur, Djuro Μacut, Dragan Micić, Renato Pasquali, Marija Pfeifer et al. · 2014
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- The pathogenic role of androgen excess in PCOSDuarte Pignatelli, Sofia Silva Pereira, Eleni Kandaraki · 2021 · Elsevier eBooks
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- Polycystic ovary syndromeRoger A. Lobo · 2021 · Elsevier eBooks
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