The DOI matches its Crossref record; 87 of the 87 references it cites were found in a registry or an index.
Long-Term Impact of Bariatric Surgery on Body Weight, Comorbidities, and Nutritional Status
Abstract
CONTEXT: The number of patients who undergo Roux-en-Y gastric bypass (RYGB) and gastric banding (GB) surgeries has increased dramatically over the past decade, yet the long-term impact of these surgeries on body weight, comorbidities, and nutritional status remains unclear, as do the mechanisms of weight regain. EVIDENCE ACQUISITION: The articles were found via PubMed searches. To review the impact of bariatric surgery on weight maintenance and comorbidities, only articles with a postoperative follow-up of 3 yr or longer were included. The articles on nutritional status had a follow-up of 12 months or longer. CONCLUSIONS: RYGB and GB surgeries lead to substantial weight loss in individuals with morbid obesity. However, significant weight regain occurs over the long term, and according to the only well-designed prospective controlled study, the improvement in comorbidities associated with weight loss mitigates in the long term on weight regain. There is some evidence from a retrospective study that RYGB surgery is associated with a modest decrease in long-term mortality. These results remain to be substantiated by well-designed, long-term, randomized and prospective controlled studies. The mechanisms that lead to weight regain need to be further examined and may include increase in energy intake due to enlargement of stoma and adaptive changes in the levels of gut and adipocyte hormones such as ghrelin and leptin, which regulate energy intake; decrease in physical activity; changes in energy expenditure; and other factors. In addition to weight regain, RYGB surgery is associated with frequent incidence of iron, vitamin B12, folate, calcium, and vitamin D deficiency, which requires regular supplementation and monitoring.
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Cites
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Prevalence of Overweight and Obesity in the United States, 1999-2004
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Bariatric Surgery: A Systematic Review and Meta-analysis
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Must, A. (1999) · JAMA · doi:10.1001/jama.282.16.1523 · Cited by 4,780
Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery
Sjöström, L., Lindroos, A.-K., Peltonen, M., Torgerson, J., Bouchard, C., Carlsson, B., Dahlgren, S., Larsson, B., Narbro, K., Sjöström, C. D., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa035622 · Cited by 4,457
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Years of Life Lost Due to Obesity
Fontaine, K. R., Redden, D. T., Wang, C., Westfall, A. O., & Allison, D. B. (2003) · JAMA · doi:10.1001/jama.289.2.187 · Cited by 2,495
Ghrelin enhances appetite and increases food intake in humans
Wren, A. M., Seal, L. J., Cohen, M. A., Brynes, A. E., Frost, G. S., Murphy, K. G., Dhillo, W. S., Ghatei, M. A., & Bloom, S. R. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.12.8111 · Cited by 2,494
Pories, W. J., Swanson, M. S., MacDonald, K. G., Long, S. B., Morris, P. G., Brown, B. M., Barakat, H. A., deRamon, R. A., Israel, G., Dolezal, J. M., et al. (1995) · Annals of Surgery · doi:10.1097/00000658-199509000-00011 · Cited by 2,293
Plasma Ghrelin Levels after Diet-Induced Weight Loss or Gastric Bypass Surgery
Cummings, D. E., Weigle, D. S., Frayo, R. S., Breen, P. A., Ma, M. K., Dellinger, E. P., & Purnell, J. Q. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012908 · Cited by 2,241
Cited by
Body Mass Index: Obesity, BMI, and Health A Critical Review
Nuttall, F. Q. (2015) · Nutrition Today · doi:10.1097/nt.0000000000000092 · Cited by 2,284
Weight Gain After Short- and Long-Limb Gastric Bypass in Patients Followed for Longer Than 10 Years
Christou, N. V., Look, D., & MacLean, L. D. (2006) · Annals of Surgery · doi:10.1097/01.sla.0000217592.04061.d5 · Cited by 728
Heber, D., Greenway, F. L., Kaplan, L. M., Livingston, E., Salvador, J., & Still, C. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2128 · Cited by 521
Bariatric Surgery: A Review of Procedures and Outcomes
Elder, K. A., & Wolfe, B. M. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.03.057 · Cited by 470
Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency
Hannibal, L., Lysne, V., Bjørke-Monsen, A.-L., Behringer, S., Grünert, S. C., Spiekerkoetter, U., Jacobsen, D. W., & Blom, H. J. (2016) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2016.00027 · Cited by 355
Metadata
- Authors
- Shah, M., Simha, V., & Garg, A.
- Venue
- The Journal of Clinical Endocrinology & Metabolism
- Publisher
- The Endocrine Society
- Published
- 2006-11-01
- Volume
- 91
- Issue
- 11
- Pages
- 4223-4231
- ISSN
- 0021-972X (ISSN-L)
- 1945-7197
- OpenAlex
- W2071196731
- Cited by
- 433
- References
- 87
- FWCI
- 22.13
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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