Progressive Reduction in Body Weight after Treatment with the Amylin Analog Pramlintide in Obese Subjects: A Phase 2, Randomized, Placebo-Controlled, Dose-Escalation Study
Aronne, Louis, Fujioka, Ken, Aroda, Vanita, Chen, Kim, Halseth, Amy, Kesty, Nicole C., Burns, Colleen, Lush, Cameron W. +1 more·2007·The Journal of Clinical Endocrinology & Metabolism
Cited by (178)
Items 101–178 of 178
- Safety, tolerability and pharmacokinetic characterisation of DACRA KBP‐042 in healthy male subjectsKim Henriksen, Karen Broekhuizen, Wadim M. I. de Boon, M.A. Karsdal, Asger Reinstrup Bihlet, Claus Christiansen, Marlous R. Dillingh, Marieke de Kam, Raj Kumar, Jacobus Burggraaf et al. · 2021 · British Journal of Clinical Pharmacology
- Salmon Calcitonin Attenuates Some Behavioural Responses to Nicotine in Male MiceCajsa Aranäs, Jesper Vestlund, Sarah Witley, Christian E. Edvardsson, Aimilia Lydia Kalafateli, Elisabet Jerlhag · 2021 · Frontiers in Pharmacology
- Pharmacotherapy for obesityLisa M. Neff, Louis J. Aronne · 2007 · Current Atherosclerosis Reports
- The Dual Amylin and Calcitonin Receptor Agonist, KBP-066, Induces an Equally Potent Weight Loss Across a Broad Dose Range While Higher Doses May Further Improve Insulin ActionNina Sonne, Anna Thorsø Larsen, Kim Vietz Andreassen, M.A. Karsdal, Kim Henriksen · 2020 · Journal of Pharmacology and Experimental Therapeutics
- Improved metabolic efficacy of a dual amylin and calcitonin receptor agonist when combined with semaglutide or empagliflozinSimone Anna Melander, Anna Katri, M.A. Karsdal, Kim Henriksen · 2022 · European Journal of Pharmacology
- Dose Frequency Optimization of the Dual Amylin and Calcitonin Receptor Agonist KBP-088: Long-Lasting Improvement in Food Preference and Body Weight LossAnna Thorsø Larsen, Nina Sonne, Kim Vietz Andreassen, M.A. Karsdal, Kim Henriksen · 2020 · Journal of Pharmacology and Experimental Therapeutics
- Glycomacropeptide Impacts Amylin-Mediated Satiety, Postprandial Markers of Glucose Homeostasis, and the Fecal Microbiome in Obese Postmenopausal WomenKaren E. Hansen, Sangita G. Murali, Ibrahim Zúñiga-Chaves, Garret Suen, Denise Marie Ney · 2023 · Journal of Nutrition
- Gut hormones such as amylin and GLP-1 in the control of eating and energy expenditureThomas A. Lutz · 2016 · International Journal of Obesity Supplements
- Weight-Loss Pharmacotherapy: A Brief ReviewMary Margaret Huizinga · 2007 · Clinical Diabetes
- ObesitySamuel Klein, Johannes Anthonius Romijn · 2016 · Elsevier eBooks
- Weight-centric pharmacological management of type 2 diabetes mellitus – An essential component of cardiovascular disease preventionEmir M. Muzurović, Siniša Dragnić, Sanja Medenica, Brigita Smolović, Predrag Bulajić, Dimitri P. Mikhailidis · 2020 · Journal of Diabetes and its Complications
- Approaches to the pharmacological treatment of obesityVictoria Salem, Stephen Robert Bloom · 2009 · Expert Review of Clinical Pharmacology
- Visceral Adiposity, Insulin Resistance, and Type 2 DiabetesMichelle L. Griffith, Lisa M. Younk, Stephen N. Davis · 2010 · American Journal of Lifestyle Medicine
- Gastrointestinal regulatory peptides and central nervous system mechanisms of weight controlEllen E. Ladenheim · 2012 · Current Opinion in Endocrinology Diabetes and Obesity
- The long-acting amylin/calcitonin receptor agonist ZP5461 suppresses food intake and body weight in male ratsLauren Michelle Stein, Lauren E. McGrath, Rinzin Lhamo, Kieran Koch‐Laskowski, Samantha M. Fortin, Jolanta Skarbaliene, Tamara Baader-Pagler, Rasmus Just, Matthew R. Hayes, Elizabeth G. Mietlicki‐Baase · 2021 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Plasma Amylin and Cognition in Diabetes in the Absence and the Presence of Insulin TreatmentWei Qiao Qiu · 2014 · Journal of Diabetes & Metabolism
- Hormone-based therapies in the regulation of fuel metabolism and body weightNicole C. Kesty, Jonathan David Roth, David G. Maggs · 2008 · Expert Opinion on Biological Therapy
- Food intake and meal pattern in IAPP knockout mice with and without infusion of exogenous IAPPM. Olsson, M. Herrington, R. Reidelberger, J. Permert, S. Gebre-Medhin, U. Arnelo · 2012 · Scandinavian Journal of Gastroenterology
- Optimizing Diabetes Treatment Using an Amylin AnalogueSteven V. Edelman · 2008 · The Science of Diabetes Self-Management and Care
- Poly(ADP-Ribose) Polymerase Inhibitors for Arsenic Trioxide–Resistant Acute Promyelocytic Leukemia: Synergistic In Vitro Antitumor Effects with Hypomethylating Agents or High-Dose Vitamin CManuela Giansanti, Antonio De Gabrieli, Salvatore Pasquale Prete, Tiziana Ottone, Maria Domenica Divona, Terry Karimi, Fabio Ciccarone, Maria Teresa Voso, Grazia Graziani, Isabella Faraoni · 2021 · Journal of Pharmacology and Experimental Therapeutics
- Anti-Obesity Pharmacotherapy and the Potential for Preventing Progression from Prediabetes to Type 2 DiabetesAlan J. Garber · 2015 · Endocrine Practice
- Amylin in vasodilation, energy expenditure and inflammationFan Yang · 2014 · Frontiers in bioscience
- The protective effect of Azadirachta excelsa leaves extract and quercetin treatment on the learning and memory impairments in relation with insulin and amylin levels in the brain of streptozotocin-induced diabetic ratsNoor Syaffinaz Noor Mohamad Zin, Nooraain Hashim, Nurdiana Samsulrizal, Nur Syimal’ain Azmi · 2018 · Journal of King Saud University - Science
- Long-acting amylin analogue for weight reductionKishore M Gadde, David B. Allison · 2021 · The Lancet
- Current Management of Obesity in an Infertile Female-Recent Advances and Future Prospective DrugsKulvinder Kochar Kaur, Gautam Allahbadia, Mandeep Singh · 2013 · Journal of Pharmacy and Nutrition Sciences
- Pharmacologic management of obesityRobert F. Kushner · 2011 · Pediatric Blood & Cancer
- Pharmacotherapy for chronic obesity management: a look into the futureMariana Abdel-Malek, Lisa Y. Yang, Alexander Dimitri Miras · 2023 · Internal and Emergency Medicine
- Iatrogenic ObesityRekha B. Kumar, Louis J. Aronne · 2020 · Endocrinology and Metabolism Clinics of North America
- Amylin receptors as therapeutic targets in obesity: Emerging peptide-based strategiesMokhtar Saeed Rejili, Md Sadique Hussain, Yumna Khan, Faouzi Haouala, Subbulakshmi Ganesan, Samir Sahoo, Amrita Pal, Vimal Arora · 2025 · Vascular Pharmacology
- Eloralintide, a selective, long‐acting amylin receptor agonist for treatment of obesity: Phase 1 proof of conceptShobha Bhattachar, Lai San Tham, Beth Tidemann‐Miller, Hilda Ibriga, Hongchang Qu, Daniel A. Briere, Axel Haupt, Kieren J. Mather, Edward John Pratt · 2026 · Diabetes Obesity and Metabolism
- Farmakoterapia otyłości — obecny stan wiedzyBeata Matyjaszek‐Matuszek, Aneta Szafraniec, Dominik Porada · 2018 · Endokrynologia Polska
- Effects of pramlintide on energy intake and food preference in rats given a choice dietKatherine A. Kern, Adrianne M. DiBrog, Johnathan T. Przybysz, Elizabeth G. Mietlicki‐Baase · 2021 · Physiology & Behavior
- Amylin analogs for the treatment of obesity without diabetes: present and futureTheodoros Panou, Evanthia Gouveri, Djordje S. Popovic, Νικόλαος Παπάνας · 2024 · Expert Review of Clinical Pharmacology
- Amylin Level and Gastric Emptying in Obese Children : Before and after Weight LossOmnia F. El-Rasheidy, Dina Amin Saleh, Hala Abdalrahman Ahmed · 2012 · Journal of the Egyptian Society of Parasitology
- Current and Future Medical Treatment of ObesityDevika Umashanker, Leon I. Igel, Rekha B. Kumar, Louis J. Aronne · 2017 · Gastrointestinal Endoscopy Clinics of North America
- Modeling energy intake and body weight effects of a long-acting amylin analogueAnnika Brings, Jens Markus Borghardt, Jolanta Skarbaliene, Tamara Baader-Pagler, Maria A. Deryabina, Wolfgang Rist, Stefan Scheuerer · 2017 · Journal of Pharmacokinetics and Pharmacodynamics
- Targeting the Enteroendocrine System for Treatment of ObesityEmily L. Miedzybrodzka, Fiona Mary Gribble, Frank M. Reimann · 2022 · Handbook of experimental pharmacology
- Pharmacotherapy for obesity: a field in crisis?Wiebke Kristin Fenske, Jennifer Parker, Stephen Robert Bloom · 2011 · Expert Review of Endocrinology & Metabolism
- Oral Amylin Treatment Reduces the Pathological Cascade of Alzheimer’s Disease in a Mouse ModelHana Na, Hua Tian, Zheng-Rong Zhang, Qiang Li, Jack B. Yang, Liam Mcparland, Qini Gan, Wei Q. Qiu · 2021 · American Journal of Alzheimers Disease & Other Dementias
- A Survey and Guide to the Development of Fatty Acid‐derivatized Peptide TherapeuticsMichael T. Jacobsen, Christian Poulsen, Katharina L. Kopp, Jørgen Olsen, Nick Cox · 2025 · Peptide Science
- ObesitySamuel Klein, Elisa Fabbrini, Johannes Anthonius Romijn · 2011 · Elsevier eBooks
- Promising areas of pharmacotherapy for obesityМ. A. Druzhilov, Т. Yu. Kuznetsova, Galina A. Chumakova · 2021 · Russian Journal of Cardiology
- Steve Woods's contribution to research on amylin's eating inhibitory effect.T. Lutz · 2011 · Physiology and Behavior
- The Central Question of Type 2 DiabetesThaïs Rouquet, Marion S. Bonnet, Pierre Clément, Michel Dallaporta, Jean‐Denis Troadec, Julien Roux, Bruno Bariohay · 2013 · Pharmaceutical Patent Analyst
- Pramlintide: profile of an amylin analogHarold E. Lebovitz · 2012 · Expert Review of Endocrinology & Metabolism
- Chronic pramlintide decreases feeding via a reduction in meal size in male ratsKatherine A. Kern, Adrianne M. DiBrog, Kiran Kaur, Johnathan T. Przybysz, Elizabeth G. Mietlicki‐Baase · 2024 · Peptides
- Medical Management of Obesity as it Affects RefluxJames D. Haddad, Shawn L. Shah · 2021 · Foregut The Journal of the American Foregut Society
- Investigating the Physiologic Role of Leptin and Its Relationship to ObesityMohammed Kallash, William H. Frishman · 2025 · Cardiology in Review
- Insulin, other hypoglycemic drugs, and glucagonRenee C. Page · 2010 · Side effects of drugs annual
- New Directions in the Pharmacological Treatment of Food Addiction, Overeating, and ObesityAmelia A. Davis, Paula J. Edge, Mark S. Gold · 2014 · Elsevier eBooks
- Eating BehaviorBlundell, John E., Finlayson, Graham, Halford, Jason C. G. · 2009 · Clinical Obesity in Adults and Children
- A Review of Amylin Peptide Receptor Activators for Obesity PharmacotherapySang Min Lee · 2025 · Current Drug Targets
- Utilidad de los fármacos antiobesidad en la diabetes mellitus tipo 2Johann Elie Aguilar Quevedo, J. Tur, Guillermo Serra, Bartolome G. Burguera · 2010 · Avances en Diabetología
- Introduction – Obesity and Food Intake: Basic and Clinical ApproachesAnnette D. de Kloet, Stephen C. Woods · 2009 · Forum of nutrition/Bibliotheca Nutritio et dieta
- Obesity: Medical and Surgical TreatmentDaniele Tassinari, Alessandro Giovanelli, Carmela Asteria · 2021 · Springer eBooks
- DIET-INDUCED OBESITY: DOPAMINERGIC AND BEHAVIORAL MECHANISMS AS OUTCOMES AND PREDICTORSVidya Narayanaswami · 2013 · UKnowledge (University of Kentucky)
- Environmental Inputs, Intake of Nutrients, and Endogenous Molecules Contributing to the Regulation of Energy HomeostasisTheodoros Kelesidis, Iosif Kelesidis, Christos Socrates Mantzoros · 2009 · Humana Press eBooks
- Adjunctive Therapy, Including PharmacotherapyDalal Y. Al-Bazz, John P.H. Wilding · 2022 · Wiley eBooks
- Pharmacological Management of the Obese PatientDonald Schumacher · 2013 · American Journal of Lifestyle Medicine
- Pramlintide in the Management of ObesityMelissa C. Jones, Heather F. DeBellis, Barefield, Kimberly L · 2010 · Clinical Medicine Reviews in Therapeutics
- Experimental models for investigating IAPP regulation of food intake in rats and miceMadelene Olsson · 2012 · Figshare
- Preguntas y respuestas sobre aspectos generales del tratamiento farmacológico en el paciente obesoJosé Hernández Rodríguez, Manuel Emiliano Licea Puig, Lizet Castelo Elías-Calles · 2013 · DOAJ (DOAJ: Directory of Open Access Journals)
- Medicamentos que favorecen la pérdida de peso y el control metabólico en las personas obesas con diabetesJosé Hernández Rodríguez, Manuel Emiliano Licea Puig · 2013
- The Renin-Angiotensin System and the Neuroendocrine Regulation of Energy BalanceE. R. de Kloet, D. Rieg Annette · 2011 · OhioLink ETD Center (Ohio Library and Information Network)
- Lixisenatide: A New Glucagon-Like Peptide-1 AgonistChristopher W. Ho · 2013 · Journal of Developing Drugs
- inhibitory effect kinase 1/2 signaling pathway in amylin's eating Involvement of the extracellular signal-regulatedThomas A. Lutz, Catarina Soares Potes, Christina N. Boyle, Peter John Wookey · 2012
- Pharmacologie de l'obésité : vers de nouvelles optionsKarine Clément, Olivier Ziegler · 2021 · Elsevier eBooks
- Advances in Pharmacological Treatment of Pediatric ObesityMichael I. Goran · 2016 · CRC Press eBooks
- Amylin analogues2015 · Elsevier eBooks
- Central pramlintide administration potently suppresses operant responding for sucrose and locomotor activity in male ratsKatherine A. Kern, Adrianne M. DiBrog, Emily Demieri, Johnathan T. Przybysz, Stewart D. Clark, Elizabeth G. Mietlicki‐Baase · 2025 · Physiology & Behavior
- Synthetic and anti-obesity potential of some fused heterocyclic compounds: a comprehensive updatePooja M. Kadu, Utpal Jagdish Dongre, Pankaj V. Ledade, Sami H. Mahmood, Trimurti L. Lambat · 2025 · Chemical Papers
- Additional file 2 of The dual amylin and calcitonin receptor agonist KBP-089 and the GLP-1 receptor agonist liraglutide act complimentarily on body weight reduction and metabolic profileAnna Thorsø Larsen, Sofie Gydesen, Nina Sonne, Karsdal, Morten Asser, Henriksen, Kim · 2021 · Figshare
- Additional file 1 of The dual amylin and calcitonin receptor agonist KBP-089 and the GLP-1 receptor agonist liraglutide act complimentarily on body weight reduction and metabolic profileAnna Thorsø Larsen, Sofie Gydesen, Nina Sonne, Karsdal, Morten Asser, Henriksen, Kim · 2021 · Figshare
- Implication des neurones exprimant NUCB2/nesfatine-1 dans la régulation de l'homéostasie énergétiqueMarion S. Bonnet · 2013 · theses.fr (ABES)
- Beyond GLP-1: Amylin-based pharmacotherapy and the search for better-tolerated weight-loss drugsSophia L. Fischer, Tito Borner · 2026 · Pharmacological Research
- Can Leptin Responsiveness Be Restored in Common Human Obesity?J. A. M. J. L. Janssen · 2026 · Lipidology
- Effect of GLP‐1 receptor agonist on nutrient intake: A narrative reviewKen Fujioka · 2026 · Nutrition in Clinical Practice
- New Amylin-Based Agonists for the Treatment of Obesity and Type 2 Diabetes MellitusTheodoros Panou, Evanthia Gouveri, Djordje S. Popovic, Νικόλαος Παπάνας · 2026 · Diabetes Therapy