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Hamann, L. G., Manfredi, M. C., Sun, C., Krystek, S. R., Huang, Y., Bi, Y., Augeri, D. J., Wang, T., Zou, Y., Betebenner, D. A., et al. (2007) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2007.01.076 · Cited by 31

Effect of long-acting testosterone undecanoate treatment on quality of life in men with testosterone deficiency syndrome: a double blind randomized controlled trial

Tong, S. F., Ng, C. J., Lee, B.-C., Lee, V. K. M., Khoo, E. M., Lee, E.-G., & Tan, H. M. (2012) · Asian Journal of Andrology · doi:10.1038/aja.2011.178 · Cited by 34

Serum testosterone level and related metabolic factors in men over 70 years old

Tang, Y., Lee, W. J., Chen, Y. T., LIU, P., Lee, M. C., & Sheu, W. H. (2007) · Journal of Endocrinological Investigation · doi:10.1007/bf03346327 · Cited by 30

Persistence of androgenic effects on the production of proinflammatory cytokines by circulating antigen-presenting cells after withdrawal of testosterone treatment in aging type 2 diabetic men with partial androgen deficiency

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Body fat in men with prolactinoma

Naliato, E. C. O., Violante, A., Gaccione, M., Caldas, D., Filho, A. L., Loureiro, C. R., Fontes, R. G., Schrank, Y., Costa, F. S. R., & Colao, A. A. L. (2008) · Journal of Endocrinological Investigation · doi:10.1007/bf03345636 · Cited by 29

Hypogonadism is Common in Men With Myopathies

Al‐Harbi, T., Bainbridge, L. J., McQueen, M., & Tarnopolsky, M. A. (2008) · Journal of Clinical Neuromuscular Disease · doi:10.1097/cnd.0b013e318176eb55 · Cited by 28

Androgens and male aging: current evidence of safety and efficacy

Gooren, L. J. (2010) · Asian Journal of Andrology · doi:10.1038/aja.2010.4 · Cited by 29

Normative hypogonadism and depression: does ‘andropause’ exist?

Seidman, S. N. (2006) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901443 · Cited by 29

Hormone replacement in the aging male?☆

Hermann, M., & Berger, P. (1999) · Experimental Gerontology · doi:10.1016/s0531-5565(99)00069-8 · Cited by 29

One size may not fit all: anti-aging therapies and sarcopenia

Burks, T. N., & Cohn, R. D. (2011) · Aging · doi:10.18632/aging.100409 · Cited by 29

Testosterone stimulates extra‐hepatic but not hepatic fat oxidation (Fox): comparison of oral and transdermal testosterone administration in hypopituitary men

Birzniece, V., Meinhardt, U. J., Handelsman, D. J., & Ho, K. K. Y. (2009) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2009.03524.x · Cited by 27

A Selective Androgen Receptor Modulator (OPK-88004) in Prostate Cancer Survivors: A Randomized Trial

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Synthetic drugs with anti-ageing effects

Kapoor, V. K., Dureja, J., & Chadha, R. (2009) · Drug Discovery Today · doi:10.1016/j.drudis.2009.07.006 · Cited by 27

Physiological testosterone levels enhance chondrogenic extracellular matrix synthesis by male intervertebral disc cells in vitro, but not by mesenchymal stem cells

Bertolo, A., Baur, M., Aebli, N., Ferguson, S. J., & Stoyanov, J. V. (2013) · The Spine Journal · doi:10.1016/j.spinee.2013.10.018 · Cited by 27

Hepatic actions of androgens in the regulation of metabolism

Birzniece, V. (2018) · Current Opinion in Endocrinology Diabetes and Obesity · doi:10.1097/med.0000000000000405 · Cited by 28

Testosterone--Fountain of Youth or Drug of Abuse?

Hayes, F. J. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.9.6868 · Cited by 27

Androgens and the Regulation of Adiposity and Body Fat Distribution in Humans

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Hand-grip strength and sensation seeking

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Changes in Body Composition During Hormonal Therapy for Prostate Cancer

Smith, M. R. (2003) · Clinical Prostate Cancer · doi:10.3816/cgc.2003.n.008 · Cited by 26

Testosterone Treatment in Middle-Aged and Older Men with Hypogonadism

Bhasin, S., & Snyder, P. J. (2025) · New England Journal of Medicine · doi:10.1056/nejmra2404637 · Cited by 27

Effect of long-term testosterone therapy on molecular regulators of skeletal muscle mass and fibre-type distribution in aging men with subnormal testosterone

Kruse, R., Petersson, S. J., Christensen, L. L., Kristensen, J. M., Sabaratnam, R., Ørtenblad, N., Andersen, M., & Højlund, K. (2020) · Metabolism · doi:10.1016/j.metabol.2020.154347 · Cited by 26

Testosterone and coronary artery disease in men

Webb, C. M., & Collins, P. D. (2010) · Maturitas · doi:10.1016/j.maturitas.2010.03.029 · Cited by 25

Age-related changes in muscles and joints

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The Effects of Anabolic Androgenic Steroid Abuse on Gingival Tissues

Özçelik, O., Haytaç, M. C., & Şeydaoğlu, G. (2006) · Journal of Periodontology · doi:10.1902/jop.2006.050389 · Cited by 25

Repurposing erectile dysfunction drugs tadalafil and vardenafil to increase bone mass

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The androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via Igf1 expression in male mice

Sakai, H., Uno, H., Yamakawa, H., Tanaka, K. Y., Ikedo, A., Uezumi, A., Ohkawa, Y., & Imai, Y. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2407768121 · Cited by 25

Anabolic steroids for rehabilitation after hip fracture in older people

Farooqi, V., van den Berg, M., Cameron, I. D., & Crotty, M. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008887.pub2 · Cited by 24

Graded Inhibition of Pulsatile Luteinizing Hormone Secretion by a Selective Gonadotropin-Releasing Hormone (GnRH)-Receptor Antagonist in Healthy Men: Evidence That Age Attenuates Hypothalamic GnRH Outflow

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Anabolic steroids after total knee arthroplasty. A double blinded prospective pilot study

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DHEA and Testosterone in the Elderly

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Effects of androgen replacement on metabolism and physical performances in male hypogonadism

Zitzmann, M., & Nieschlag, E. (2003) · Journal of Endocrinological Investigation · doi:10.1007/bf03345240 · Cited by 24

Testosterone replacement therapy in male hypogonadism

Byrne, M. M., & Nieschlag, E. (2003) · Journal of Endocrinological Investigation · doi:10.1007/bf03345206 · Cited by 22

The impact of traumatic brain injury on pituitary function

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Cardiovascular safety of testosterone replacement therapy in men: an updated systematic review and meta-analysis

Corona, G., Rastrelli, G., Sparano, C., Carinci, V., Casella, G., Vignozzi, L., Sforza, A., & Maggi, M. (2024) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2024.2337741 · Cited by 26

Androgen receptor gene polymorphism and the metabolic syndrome in 60–80 years old Norwegian men

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Testosterone replacement therapy and the risk of stroke in men: A systematic review

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New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men

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PTOV1 : a novel testosterone‐induced atherogenic gene in human aorta

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Elderly people with hypothalamic–pituitary disease and growth hormone deficiency: lipid profiles, body composition and quality of life compared with control subjects

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Centenarian longevity had inverse relationships with nutritional status and abdominal obesity and positive relationships with sex hormones and bone turnover in the oldest females

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Selective androgen receptor modulators for the treatment of late onset male hypogonadism

Dalton, J. T., Coss, C. C., Jones, A., Hancock, M., & Steiner, M. (2014) · Asian Journal of Andrology · doi:10.4103/1008-682x.122339 · Cited by 22

Effects of growth hormone and/or sex steroid administration on whole-body protein turnover in healthy aged women and men

Huang, X., Blackman, M. R., Herreman, K., Pabst, K. M., Harman, S. M., & Caballero, B. H. (2005) · Metabolism · doi:10.1016/j.metabol.2005.03.023 · Cited by 21

The Need for a Men's Health Initiative

Morley, J. E. (2003) · The Journals of Gerontology Series A · doi:10.1093/gerona/58.7.m614 · Cited by 21

Testosterone as a marker of coronary artery disease severity in middle aged males

Gururani, K., Jose, J., & George, P. V. (2016) · Indian Heart Journal · doi:10.1016/j.ihj.2016.07.002 · Cited by 20

Andropause: Is the Emperor Wearing Any Clothes?

Tariq, S. H., Haren, M. T., Kim, M. J., & Morley, J. E. (2005) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-005-6719-4 · Cited by 19

MANAGEMENT OF NUTRITIONAL PROBLEMS IN SUBACUTE CARE

Morley, J. E. (2000) · Clinics in Geriatric Medicine · doi:10.1016/s0749-0690(05)70046-x · Cited by 20

Hormonal fountains of youth

Horani, M. H., & Morley, J. E. (2004) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2004.02.002 · Cited by 20

Effects of Skeletal Muscle Hypertrophy on Fat Mass and Glucose Homeostasis in Humans and Animals: A Narrative Review with Systematic Literature Search

Havers, T., Held, S., Schönfelder, M., Geisler, S., & Wackerhage, H. (2025) · Sports Medicine · doi:10.1007/s40279-025-02263-w · Cited by 19

Sex-Specific Differences in the Effect of Free Testosterone on Sarcopenia Components in Older Adults

Shin, H. E., Walston, J. D., Kim, M., & Won, C. W. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.695614 · Cited by 20

Testosterone, Diabetes Risk, and Diabetes Prevention in Men

Yeap, B. B., & Wittert, G. (2022) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2021.11.004 · Cited by 19

Androgen and estrogen actions on male physical activity: a story beyond muscle

Jardí, F., Laurent, M. R., Dubois, V., Kim, N., Khalil, R., Decallonne, B., Vanderschueren, D., & Claessens, F. (2018) · Journal of Endocrinology · doi:10.1530/joe-18-0125 · Cited by 20

Understanding the development of sarcopenic obesity

Gross, D. C., Cheever, C. R., & Batsis, J. A. (2023) · Expert Review of Endocrinology & Metabolism · doi:10.1080/17446651.2023.2267672 · Cited by 19

Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate‐sparing anabolic therapy

Jasuja, R., Costello, J. C., Singh, R., Gupta, V., Spina, C. S., Toraldo, G., Jang, H., Hu, L., Serra, C., Guo, W., et al. (2013) · Aging Cell · doi:10.1111/acel.12174 · Cited by 20

Testosterone Replacement Therapy in Reversing “Andropause”: What Is the Proof-of-Principle?

Lang, P. O., Samaras, D., & Samaras, N. (2012) · Rejuvenation Research · doi:10.1089/rej.2012.1316 · Cited by 18

Identifying effective and feasible interventions to accelerate functional recovery from hospitalization in older adults: A randomized controlled pilot trial

Deer, R., Dickinson, J. M., Fisher, S. R., Ju, H., & Volpi, E. (2016) · Contemporary Clinical Trials · doi:10.1016/j.cct.2016.05.001 · Cited by 21

Serum levels of enclomiphene and zuclomiphene in men with hypogonadism on long‐term clomiphene citrate treatment

Helo, S., Mahon, J., Ellen, J. H., Wiehle, R. D., Fontenot, G. K., Hsu, K., Feustel, P. J., Welliver, C., & McCullough, A. (2016) · British Journal of Urology · doi:10.1111/bju.13625 · Cited by 19

What Do Hormones Have to Do with Aging? What Does Aging Have to Do with Hormones?

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Generation and analysis of an androgen-responsive myoblast cell line indicates that androgens regulate myotube protein accretion

Chen, Y., Lee, N. K. L., Zajac, J. D., & MacLean, H. E. (2008) · Journal of Endocrinological Investigation · doi:10.1007/bf03346441 · Cited by 18

Guidelines for diagnosing, prevention and treatment of osteoporosis in Asia

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Testosterone Treatment As a Function-Promoting Therapy in Sarcopenia Associated with Aging and Chronic Disease

dos Santos, M. R., & Storer, T. W. (2022) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2021.11.012 · Cited by 17

Lost in translation: challenges of current pharmacotherapy for sarcopenia

Tsai, S. (2024) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2024.05.016 · Cited by 19

Gender‐specific aspects of treatment of cardiovascular risk factors in primary and secondary prevention

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Effects of Testosterone on Serum Concentrations, Fat-free Mass, and Physical Performance by Population: A Meta-analysis

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Baseline Testosterone Predicts Body Composition and Metabolic Response to Testosterone Therapy

Deepika, F., Ballato, E., Colleluori, G., Aguirre, L. E., Chen, R., Qualls, C., Villareal, D. T., & Armamento‐Villareal, R. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.915309 · Cited by 19

Analysis of Testosterone Effects on Sonic Hedgehog Signaling in Juvenile, Adolescent and Adult Sprague Dawley Rat Penis

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The role of the urologist in the prevention and early detection of cardiovascular disease

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Testosterone Therapy and Cardiovascular Risk: A Critical Analysis of Studies Reporting Increased Risk

Khera, M., Miner, M. M., Jaffe, J. S., & Pastuszak, A. W. (2020) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2020.10.019 · Cited by 16

Battle of the sex steroids in the male skeleton: and the winner is…

Weber, T. J. (2016) · Journal of Clinical Investigation · doi:10.1172/jci85006 · Cited by 15

Preliminary development of a new individualised questionnaire measuring quality of life in older men with age-related hormonal decline: the A-RHDQoL.

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A Double-Blind, Placebo-Controlled, Randomized Clinical Trial of Recombinant Human Chorionic Gonadotropin on Muscle Strength and Physical Function and Activity in Older Men with Partial Age-Related Androgen Deficiency

Liu, P. Y., Wishart, S. M., & Handelsman, D. J. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.7.8630 · Cited by 112

The aging male – diagnosis and therapy of late‐onset hypogonadism

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Change in Thigh Muscle Cross-Sectional Area Through Administration of an Anabolic Steroid During Routine Stroke Rehabilitation in Hemiplegic Patients

Okamoto, S., Sonoda, S., Tanino, G., Tomida, K., Okazaki, H., & Kondo, I. (2010) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/phm.0b013e31820172bf · Cited by 15

Testosterone Treatment in Older Men: Effects on the Prostate

Morley, J. E. (2000) · Endocrine Practice · doi:10.4158/ep.6.2.218 · Cited by 15

Is There Room for SERMs or SARMs as Alternative Therapies for Adult Male Hypogonadism?

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Sarcopenia in Immune-Mediated Rheumatic Diseases—Review

Santo, R. C. D. E., Baker, J. F., dos Santos, L. P., da Silva, M. M. M., & Xavier, R. M. (2022) · JCR Journal of Clinical Rheumatology · doi:10.1097/rhu.0000000000001913 · Cited by 14

Might Testosterone Actually Reduce Mortality?

Snyder, P. J. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-2506 · Cited by 14

Assessment of possible effects for testosterone replacement therapy in men with symptomatic late-onset hypogonadism

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Male hypogonadism in the primary care clinic

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Pharmacological treatment of frailty in the elderly

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Hypotestosteronaemia in the aging male: should we treat it?

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Sarcopenia en ancianos

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Therapeutic Interventions for Age-related Muscle Wasting

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Reproductive Complications and Sexual Dysfunction in Cancer Survivors

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IGF-I improved bone mineral density and body composition of weaver mutant mice

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