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Cited by 175

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A Radio-ligand Binding Assay System for Estradiol Measurement in Human Plasma

KORENMAN, STANLEY G., PERRIN, LAURENCE E., McCALLUM, THERESA P.·1969·The Journal of Clinical Endocrinology & Metabolism

Abstract

A new, convenient, specific, sensitive, reproducible radio-ligand binding assay system for measurement of estradiol in human plasma has been developed. The procedure compares the ability of standards and unknowns to compete for binding sites on the specific estrogen binding protein of rabbit uterine cytosol. Blank values approached 0. The mean estradiol concentration was 15 pg/ml in post-menopausal women, 24.0 pg/ml in adult men, 65.6 pg/ml during days 1–10 of the menstrual cycle, 124.5 during days 11–20, and 137.2 during days 21–31.

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Metadata

Authors
KORENMAN, S. G., PERRIN, L. E., & McCALLUM, T. P.
Venue
The Journal of Clinical Endocrinology & Metabolism
Published
1969-07
Volume
29
Issue
7
Pages
879-883
ISSN
  • 0021-972X (ISSN-L)
  • 1945-7197
OpenAlex
W2083121834
Cited by
175
References
0
FWCI
21.14
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: A Radio-ligand Binding Assay System for Estradiol Measurement in Human Plasma. https://app.cochat.ai/papers/10.1210/jcem-29-7-879
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KORENMAN, S. G., PERRIN, L. E., & McCALLUM, T. P. (1969). A Radio-ligand Binding Assay System for Estradiol Measurement in Human Plasma. The Journal of Clinical Endocrinology & Metabolism. https://doi.org/10.1210/jcem-29-7-879

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.