Analysis of FKBP51/FKBP52 Chimeras and Mutants for Hsp90 Binding and Association with Progesterone Receptor Complexes

Barent, Richard L., Nair, Satish C., Carr, Damon C., Ruan, Ying, Rimerman, Ronald A., Fulton, Jennifer, Zhang, Yan, Smith, David F.·1998·Molecular Endocrinology
DOI 10.1210/mend.12.3.0075

Cited by (165)

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  3. Primate-specific Melanoma Antigen-A11 Regulates Isoform-specific Human Progesterone Receptor-B Transactivation
    Shifeng Su, Amanda J. Blackwelder, Gail Grossman, John T. Minges, Lingwen Yuan, Steven L. Young, Elizabeth M. Wilson · 2012 · Journal of Biological Chemistry
  4. Molecular dynamics simulations of site point mutations in the TPR domain of cyclophilin 40 identify conformational states with distinct dynamic and enzymatic properties
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    Lie-Wei Wang, V. Yee, R. Weinshilboum · 2004 · Biochemical and Biophysical Research Communications - BBRC
  9. FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder
    Cruz, Bryan, Vozella, Valentina, Carper, Benjamin A., Xu, Joy C., Kirson, Dean, Hirsch, Shawn, Nolen, Tracy, Bradley, Lauren, Fain, Katie, Crawford, Meg et al. · 2023 · Neuropsychopharmacology
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    Rein, Theo · 2020 · BioEssays
  11. Progesterone receptor requires a co-chaperone for signalling in uterine biology and implantation
    Susanne L. Tranguch, David F. Smith, Sudhansu K. Dey · 2006 · Reproductive BioMedicine Online
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    D. Dilworth, Geoff Gudavicius, A. Leung, Christopher J. Nelson · 2012 · Biochemistry and cell biology = Biochimie et biologie cellulaire
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    Andrew J. Bredemeyer, P. Carrigan, T. Fehniger, David F. Smith, T. Ley · 2006 · Journal of Biological Chemistry
  14. Glucocorticoid receptor complexes form cooperatively with the Hsp90 co-chaperones Pp5 and FKBPs
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  18. Nucleocytoplasmic shuttling of the glucocorticoid receptor is influenced by tetratricopeptide repeat-containing proteins
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  20. Subdomain structure of the co-chaperone SGTA and activity of its androgen receptor client
    Andrew Paul Trotta, Eleanor F. Need, Lisa M. Butler, Luke A. Selth, Melissa A. O'Loughlin, Gerhard A. Coetzee, Wayne D. Tilley, Grant Buchanan · 2012 · Journal of Molecular Endocrinology
  21. Steroid Receptor-Associated Immunophilins: Candidates for Diverse Drug-Targeting Approaches in Disease
    Thomas Ratajczak · 2015 · Current Molecular Pharmacology
  22. Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co‐chaperone STI1
    Rachel E. Lackie, Abdul R. Razzaq, Sali M.K. Farhan, Lily R. Qiu, Gilli Moshitzky, Flávio H. Beraldo, Marilene Hohmuth Lopes, Andrzej Maciejewski, Robert Gros, Jue Fan et al. · 2019 · Journal of Neurochemistry
  23. Coupling of Conformational Transitions in the N-terminal Domain of the 51-kDa FK506-binding Protein (FKBP51) Near Its Site of Interaction with the Steroid Receptor Proteins*
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  25. Regulation of the Hsp90-binding immunophilin, cyclophilin 40, is mediated by multiple sites for GA-binding protein (GABP)
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  26. Co-chaperones of Hsp90 inPlasmodium falciparumand their concerted roles in cellular regulation
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  27. The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein
    J. Pearson, Z. Mohammed, J. Bacani, R. Lai, R. Ingham · 2012 · BMC Cancer
  28. Biological relevance of Hsp90‐binding immunophilins in cancer development and treatment
    Gisela I. Mazaira, María F. Camisay, Sonia A. De Leo, Alejandra G. Erlejman, Mario D. Galigniana · 2015 · International Journal of Cancer
  29. Cloning, expression and characterisation of FKB-6, the sole large TPR-containing immunophilin from C. elegans.
    J. Richardson, J. Dornan, Monluedee Opamawutthikul, S. Bruce, A. P. Page, M. Walkinshaw · 2007 · Biochemical and Biophysical Research Communications - BBRC
  30. Interaction of Heat Shock Protein 90 and the Co-chaperone Cpr6 with Ura2, a Bifunctional Enzyme Required for Pyrimidine Biosynthesis*
    A. Zuehlke, Nicholas S. Wren, Victoria R. Tenge, Jill L. Johnson · 2013 · Journal of Biological Chemistry
  31. The evolution and diversification of the Hsp90 co-chaperone system
    Sonja Engler, Johannes Büchner · 2025 · Biological Chemistry
  32. Inhibition of the FKBP family of peptidyl prolyl isomerases induces abortive translocation and degradation of the cellular prion protein
    Paweł Stocki, Maxime Sawicki, Charles E. Mays, Seo Jung Hong, Daniel C. Chapman, David A. Westaway, David B. Williams · 2016 · Molecular Biology of the Cell
  33. Signal-transduction pathways involved in the hypertrophic effect of hsp56 in neonatal cardiomyocytes.
    Y. Jamshidi, A. Zourlidou, C. Carroll, J. Sinclair, D. Latchman · 2004 · Journal of Molecular and Cellular Cardiology
  34. FKBP4 regulates 5-fluorouracil sensitivity in colon cancer by controlling mitochondrial respiration
    Zhenyu Zhu, Qing-Sheng Hou, Bi-Shi Wang, Changhao Li, Lu-Guang Liu, Wei-Peng Gong, J. Chai, Hong-Liang Guo, Yan-Han Jia · 2022 · Life Science Alliance
  35. Immunosuppression with tacrolimus improved implantation and rescued expression of uterine progesterone receptor and its co-regulators FKBP52 and PIASy at nidation in the obese and diabetic mice: Comparative studies with metformin
    Ahmad J. H. Albaghdadi, Frederick W. K. Kan · 2017 · Molecular and Cellular Endocrinology
  36. The Emerging Role of TPR-Domain Immunophilins in the Mechanism of Action of Steroid Receptors
    Gisela I. Mazaira, Mariana Lagadari, Alejandra G. Erlejman, Mario D. Galigniana · 2014 · Nuclear Receptor Research
  37. Prenatal alcohol exposure alters mRNA expression for stress peptides, glucocorticoid receptor function and immune factors in acutely stressed neonatal brain
    Chaselyn D. Ruffaner‐Hanson, Annette K. Fernandez-Oropeza, Melody S. Sun, Kevin K. Caldwell, Andrea M. Allan, Daniel D. Savage, Carlos Fernando Valenzuela, Shahani Noor, Erin D. Milligan · 2023 · Frontiers in Neuroscience
  38. Chenodeoxycholic acid fortified diet drives ovarian steroidogenesis to improve embryo implantation through enhancing uterine receptivity via progesterone receptor signaling pathway in rats
    Meixia Chen, Xiaoyi Zhao, Zhuo Chang, Hui Liu, Longlong Zhu, Sixin Wang, Dongyang Zhang, Jing Wang · 2024 · The Journal of Nutritional Biochemistry
  39. Rapamycin inhibits AR signaling pathway in prostate cancer by interacting with the FK1 domain of FKBP51
    Jing Zhang, Dan Wu, Yong‐Xing He, Lanlan Li, Shanhui Liu, Jianzhong Lu, Huiming Gui, Yuhan Wang, Yan Tao, Hanzhang Wang et al. · 2020 · Biochemistry and Biophysics Reports
  40. Expression of FK506-binding protein 52 (FKBP52) in chorionic villi with early recurrent spontaneous abortion
    Hongyan Chen, Ou-Yang Li, Lihong Pang, Hong Xu, Xiao-Jing Fan, Haifeng Liang, Xianfeng Chen, Jun-Zhen Qing, Ru-Dian Huang, Bi-Ye Deng · 2014 · The Journal of Maternal-Fetal & Neonatal Medicine
  41. FKBP51 and FKBP12.6—Novel and tight interactors of Glomulin
    Andreas Hähle, T. Geiger, S. Merz, C. Meyners, Tian-Qi Mao, J. Kolos, F. Hausch · 2019 · PLoS ONE
  42. FKBP51 decreases cell proliferation and increases progestin sensitivity of human endometrial adenocarcinomas by inhibiting Akt
    Jing Dong, Yulian Jiao, Wenli Mu, Bingru Lu, Muyun Wei, Linying Sun, Shengnan Hu, Bin Cui, Xiaowen Liu, Zi‐Jiang Chen et al. · 2017 · Oncotarget
  43. Crystallization and preliminary crystallographic studies of the C-terminal domain of human FKBP52.
    Bei-Li Wu, Peng-Yun Li, C. Shu, B. Shen, Z. Rao · 2003 · Acta Crystallographica Section D: Biological Crystallography
  44. FKBP Co-Chaperones in Steroid Receptor Complexes
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  45. Functions of the Hsp90-Binding FKBP Immunophilins
    Marc B. Cox, David F. Smith · 2007 · Springer eBooks
  46. Differential Dynamics and Roles of FKBP51 Isoforms and Their Implications for Targeted Therapies
    Silvia Martinelli, Kathrin Hafner, Maik Ködel, Janine Arloth, Nils C. Gassen, Elisabeth B. Binder · 2024 · International Journal of Molecular Sciences
  47. Transgenic mice applications in the study of endometriosis pathogenesis
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  48. Regulation of tau by peptidyl-prolyl isomerases.
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  49. Low-Dose Tacrolimus Promotes the Migration and Invasion and Nitric Oxide Production in the Human-Derived First Trimester Extravillous Trophoblast Cells In Vitro
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  50. Functional Comparison of Human and Zebra Fish FKBP52 Confirms the Importance of the Proline-Rich Loop for Regulation of Steroid Hormone Receptor Activity
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  53. FKBP25 regulates myoblast viability and migration and is differentially expressed in in vivo models of muscle adaptation
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  60. Involvement of FKBP5, but not of stress, in alcohol memory reconsolidation
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