The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Analysis of MRI patterns aids prediction of progression in X-linked adrenoleukodystrophy
Abstract
BACKGROUND: X-linked adrenoleukodystrophy (X-ALD) has variants with widely different outcomes, hampering clinical counseling and evaluation of therapies. OBJECTIVE: To evaluate the degree to which MRI patterns can predict lesion progression. METHODS: Two hundred six boys and men with cerebral X-ALD (median age 12.2 years, mean age 18.5 years, age range 1.7 to 73.8 years) were studied. In 140 individuals, follow-up MRI were available. Data after bone marrow transplantation (BMT) were excluded. The patterns of MRI abnormalities were subdivided into five groups based on the anatomic location of the initial T2 signal hyperintensity (pattern 1: parieto-occipital white matter, pattern 2: frontal white matter, pattern 3: corticospinal tract, pattern 4: cerebellar white matter, pattern 5: concomitant parieto-occipital and frontal white matter). The X-ALD MRI Severity Scale, a 34-point scale previously described, was used in the analysis. RESULTS: Pattern 1 patients had rapid progression if contrast enhancement was present and if the MRI abnormality manifested at an early age. The latter was also true for pattern 2 patients. Based on these variables, predictive formulas were constructed for these two patterns using multiple regressions. MRI progression was much slower in pattern 3 and 4 patients, whereas in the few pattern 5 patients, it was more rapid than in any other of the patterns. Patterns 1 and 5 occurred mainly in childhood, patterns 2 and 4 in adolescence, and pattern 3 in adults. CONCLUSIONS: MRI progression in X-ALD depends on patient age, initial MRI Severity Scale score, and anatomic location of the lesion. When used in combination, these data aid the prediction of disease course and the selection of patients for BMT.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“At more advanced stages, typical confluent and symmetrical areas of T2 hyperintensity reflect demyelination in the splenium of the corpus callosum, parieto-occipital or frontal white matter, or pyramidal tracts within the internal capsules, pons, and brainstem.”
From Revisiting the Pathogenesis of X-Linked Adrenoleukodystrophy (2025) · cites this paper as [94]
In the citing paper
“Gadolinium extravasation, a hallmark of neuroinflammation and blood–brain barrier (BBB) breach, can occur early when demyelinating lesions are still restricted to the corpus callosum or pyramidal tracts but is often seen later, once the demyelinating lesions have extended [31,93,94].”
From Revisiting the Pathogenesis of X-Linked Adrenoleukodystrophy (2025) · cites this paper as [94]
Citations
Cites
The Metabolic Basis of Inherited Disease.
(1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-108-3-503_7 · Cited by 7,807
Moser, H. W., Mahmood, A., & Raymond, G. V. (2007) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0421 · Cited by 663
Self-citationShapiro, E., Krivit, W., Lockman, L., Jambaqué, I., Peters, C., Cowan, M., Harris, R., Blanche, S., Bordigoni, P., Loes, D., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(00)02629-5 · Cited by 329
Self-citationAdrenoleukodystrophy: a scoring method for brain MR observations.
(1994) · PubMed Central · Cited by 321
Self-citationKemp, S., Pujol, A., Waterham, H. R., van Geel, B. M., Boehm, C. D., Raymond, G. V., Cutting, G. R., Wanders, R. J. A., & Moser, H. W. (2001) · Human Mutation · doi:10.1002/humu.1227 · Cited by 321
Self-citationThe gene responsible for adrenoleukodystrophy encodes a peroxisomal membrane protein
Mosser, J., Lutz, Y., Stoeckel, M. E., Sarde, C. O., Kretz, C., Douar, A. M., Lopez, J., Aubourg, P., & Mandel, J. L. (1994) · Human Molecular Genetics · doi:10.1093/hmg/3.2.265 · Cited by 281
POWERS, J. M., LIU, Y., MOSER, A. B., & MOSER, H. W. (1992) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199211000-00007 · Cited by 265
Self-citationLombard-Platet, G., Savary, S., Sarde, C. O., Mandel, J. L., & Chimini, G. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.3.1265 · Cited by 222
Moser, H. W., Loes, D. J., Melhem, E. R., Raymond, G. V., Bezman, L., Cox, C. S., & Lu, S.-E. (2000) · Neuropediatrics · doi:10.1055/s-2000-9236 · Cited by 210
Self-citationAdrenomyeloneuropathy: A Neuropathologic Review Featuring Its Noninflammatory Myelopathy
Powers, J. M., DeCiero, D. P., Ito, M., Moser, A. B., & Moser, H. W. (2000) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/59.2.89 · Cited by 204
Self-citation
Research works printed but not linked: 1
- Aubourg P. X-linked adrenoleukodystrophy. In: Moser HW ed. Handbook of clinical neurology. New York: Elsevier Science 1996: 447–472.
Cited by
Sorted by citations
Moser, H. W., Mahmood, A., & Raymond, G. V. (2007) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0421 · Cited by 663
Self-citationHematopoietic stem-cell gene therapy for cerebral adrenoleukodystrophy
Eichler, F., Duncan, C., Musolino, P. L., Orchard, P. J., De Oliveira, S., Thrasher, A. J., Armant, M., Dansereau, C., Lund, T. C., Miller, W. P., et al. (2017) · New England Journal of Medicine · doi:10.1056/nejmoa1700554 · Cited by 604
Self-citationPeters, C., Charnas, L. R., Tan, Y., Ziegler, R. S., Shapiro, E. G., DeFor, T., Grewal, S. S., Orchard, P. J., Abel, S. L., Goldman, A. I., et al. (2004) · Blood · doi:10.1182/blood-2003-10-3402 · Cited by 374
Self-citationAxonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes
Kassmann, C. M., Lappe-Siefke, C., Baes, M., Brügger, B., Mildner, A., Werner, H. B., Natt, O., Michaelis, T., Prinz, M., Frahm, J., et al. (2007) · Nature Genetics · doi:10.1038/ng2070 · Cited by 357
Adrenoleukodystrophy—Neuroendocrine pathogenesis and redefinition of natural history
Kemp, S., Huffnagel, I. C., Linthorst, G. E., Wanders, R. J., & Engelen, M. (2016) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.90 · Cited by 275
Turk, B. R., Theda, C., Fatemi, A. S., & Moser, A. B. (2020) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.10003 · Cited by 212
Self-citationNiemann–Pick C disease in Spain: Clinical spectrum and development of a disability scale
Iturriaga, C., Pineda, M., Fernández-Valero, E. M., Vanier, M. T., & Coll, M. J. (2006) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2006.05.054 · Cited by 147
Adrenoleukodystrophy: New Approaches to a Neurodegenerative Disease
Moser, H. W., Raymond, G. V., & Dubey, P. (2005) · JAMA · doi:10.1001/jama.294.24.3131 · Cited by 142
Self-citationLynch, D. S., Wade, C., de Paiva, A. R. B., John, N. A., Kinsella, J. A., Merwick, Á., Ahmed, R. M., Warren, J. D., Mummery, C. J., Schott, J. M., et al. (2018) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2018-319481 · Cited by 146
Vogel, B. H., Bradley, S. E., Adams, D. J., D'Aco, K., Erbe, R. W., Fong, C., Iglesias, A., Kronn, D., Levy, P., Morrissey, M., et al. (2015) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2015.02.002 · Cited by 123
Self-citationBoelens, J. J., Prasad, V. K., Tolar, J., Wynn, R. F., & Peters, C. (2010) · Pediatric Clinics of North America · doi:10.1016/j.pcl.2009.11.004 · Cited by 121
Childhood leukodystrophies: a clinical perspective
Kohlschütter, A., & Eichler, F. (2011) · Expert Review of Neurotherapeutics · doi:10.1586/ern.11.135 · Cited by 109
Hematopoietic Stem Cell Transplantation in Inborn Errors of Metabolism
Tan, E. Y., Boelens, J. J., Jones, S. A., & Wynn, R. F. (2019) · Frontiers in Pediatrics · doi:10.3389/fped.2019.00433 · Cited by 104
Fine, A. S., Nemeth, C. L., Kaufman, M. L., & Fatemi, A. S. (2019) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-019-9292-y · Cited by 104
Self-citationOutcomes of Unrelated Umbilical Cord Blood Transplantation for X-Linked Adrenoleukodystrophy
Beam, D., Poe, M. D., Provenzale, J. M., Szabolcs, P., Martin, P., Prasad, V. K., Parikh, S. H., Driscoll, T., Mukundan, S. V., Kurtzberg, J., et al. (2007) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2007.01.082 · Cited by 98
Kuruppu, D. K., & Matthews, B. R. (2013) · Seminars in Neurology · doi:10.1055/s-0033-1359320 · Cited by 106
The latest on leukodystrophies
Schiffmann, R., & van der Knaap, M. S. (2004) · Current Opinion in Neurology · doi:10.1097/00019052-200404000-00017 · Cited by 95
Bergner, C. G., van der Meer, F., Winkler, A., Wrzos, C., Türkmen, M., Valizada, E., Fitzner, D., Hametner, S., Hartmann, C., Pfeifenbring, S., et al. (2019) · Glia · doi:10.1002/glia.23598 · Cited by 94
“…correlation with data from prior autopsy and longitudinal MRI studies with regard to the typical evolution and spread of lesions (Eichler et al., 2009; Loes et al., 1994; Loes et al., 2003; Musolino et al., 2012; Schaumburg, Powers, Raine, Suzuki, & Richardson, 1975; van der Knaap & Valk, 2005).”
BackgroundResultInfluentialAdult Leukodystrophies: A Step-by-Step Diagnostic Approach
Resende, L. L., de Paiva, A. R. B., Kok, F., Leite, C. D. C., & Lucato, L. T. (2019) · Radiographics · doi:10.1148/rg.2019180081 · Cited by 94
Brain endothelial dysfunction in cerebral adrenoleukodystrophy
Musolino, P. L., Gong, Y., Snyder, J. M. T., Jimenez, S., Lok, J., Lo, E. H., Moser, A. B., Grabowski, E. F., Frosch, M. P., & Eichler, F. S. (2015) · Brain · doi:10.1093/brain/awv250 · Cited by 92
Hematopoietic Cell Therapy for Metabolic Disease
Orchard, P. J., Blazar, B. R., Wagner, J. E., Charnas, L. R., Krivit, W. A., & Tolar, J. (2007) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2007.04.054 · Cited by 90
Mallack, E. J., Turk, B. R., Yan, H., Price, C., Demetres, M., Moser, A. B., Becker, C., Hollandsworth, K., Adang, L., Vanderver, A., et al. (2021) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.12356 · Cited by 79
Self-citationKühl, J.-S., Suarez, F., Gillett, G. T., Hemmati, P. G., Snowden, J. A., Stadler, M., Vuong, G. L., Aubourg, P., Köhler, W., & Arnold, R. (2017) · Brain · doi:10.1093/brain/awx016 · Cited by 78
The changing face of adrenoleukodystrophy
Zhu, J., Eichler, F., Biffi, A., Duncan, C. N., Williams, D. A., & Majzoub, J. A. (2020) · Endocrine Reviews · doi:10.1210/endrev/bnaa013 · Cited by 78
Kim, J. H., & Kim, H. J. (2005) · Radiographics · doi:10.1148/rg.253045118 · Cited by 72
MRI brain lesions in asymptomatic boys with X-linked adrenoleukodystrophy
Liberato, A. P., Mallack, E. J., Aziz-Bose, R., Hayden, D., Lauer, A., Caruso, P. A., Musolino, P. L., & Eichler, F. S. (2019) · Neurology · doi:10.1212/wnl.0000000000007294 · Cited by 69
Treatment of cerebral adrenoleukodystrophy: allogeneic transplantation and lentiviral gene therapy
Gupta, A. O., Raymond, G., Pierpont, E. I., Kemp, S., McIvor, R. S., Rayannavar, A., Miller, B., Lund, T. C., & Orchard, P. J. (2022) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2022.2124857 · Cited by 67
Self-citationEvaluation of X-Linked Adrenoleukodystrophy Newborn Screening in North Carolina
Lee, S., Clinard, K., Young, S. P., Rehder, C. W., Fan, Z., Calikoglu, A. S., Bali, D. S., Bailey, D. B., Gehtland, L. M., Millington, D. S., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.20356 · Cited by 67
Transplantation in inborn errors of metabolism: current considerations and future perspectives
Boelens, J. J., Orchard, P. J., & Wynn, R. F. (2014) · British Journal of Haematology · doi:10.1111/bjh.13059 · Cited by 66
Magnetization transfer MRI demonstrates spinal cord abnormalities in adrenomyeloneuropathy
Fatemi, A., Smith, S. A., Dubey, P., Zackowski, K. M., Bastian, A. J., van Zijl, P. C., Moser, H. W., Raymond, G. V., & Golay, X. (2005) · Neurology · doi:10.1212/01.wnl.0000164458.02141.06 · Cited by 64
Self-citationEichler, F., Mahmood, A., Loes, D. J., Bezman, L., Lin, D., Moser, H. W., & Raymond, G. V. (2007) · Archives of Neurology · doi:10.1001/archneur.64.5.659 · Cited by 60
Self-citationWeisfeld‐Adams, J. D., Sand, I. K., Honce, J. M., & LUBLIN, F. D. (2015) · Brain · doi:10.1093/brain/awu397 · Cited by 59
Therapy of X-linked adrenoleukodystrophy
Moser, H. W. (2006) · NeuroRx · doi:10.1016/j.nurx.2006.01.004 · Cited by 59
Self-citationTheda, C., Gibbons, K., DeFor, T. E., Donohue, P. K., Golden, W. C., Kline, A. D., Gulamali-Majid, F., Panny, S. R., Hubbard, W. C., Jones, R. O., et al. (2014) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2013.10.019 · Cited by 56
Self-citationEndocrine Dysfunction in X-Linked Adrenoleukodystrophy
Burtman, E., & Regelmann, M. O. (2016) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2016.01.003 · Cited by 52
ABCD1 dysfunction alters white matter microvascular perfusion
Lauer, A., Da, X., Hansen, M. B., Boulouis, G., Ou, Y., Cai, X., Liberato Celso Pedrotti, A., Kalpathy-Cramer, J., Caruso, P., Hayden, D. L., et al. (2017) · Brain · doi:10.1093/brain/awx262 · Cited by 48
Köhler, W., Engelen, M., Eichler, F., Lachmann, R., Fatemi, A., Sampson, J., Salsano, E., Gamez, J., Molnar, M. J., Pascual, S., et al. (2023) · The Lancet Neurology · doi:10.1016/s1474-4422(22)00495-1 · Cited by 48
Self-citationAshrafi, M. R., & Tavasoli, A. R. (2017) · Brain and Development · doi:10.1016/j.braindev.2017.01.001 · Cited by 48
Page, K. M., Stenger, E. O., Connelly, J. A., Shyr, D. C., West, T., Wood, S. J., Case, L. E., Kester, M., Shim, S., Hammond, L., et al. (2019) · Transplantation and Cellular Therapy · doi:10.1016/j.bbmt.2019.09.003 · Cited by 49
Self-citationMiller, W. P., Mantovani, L. F. A. L., Muzic, J. G., Rykken, J., Gawande, R. S., Lund, T. C., Shanley, R., Raymond, G. V., Orchard, P. J., & Nascene, D. R. (2015) · American Journal of Neuroradiology · doi:10.3174/ajnr.a4500 · Cited by 45
Self-citationKühl, J., Kupper, J., Baqué, H., Ebell, W., Gärtner, J., Korenke, G. C., Spors, B., Steffen, I. G., Strauß, G., Voigt, S., et al. (2018) · JAMA Network Open · doi:10.1001/jamanetworkopen.2018.0769 · Cited by 44
Spectroscopic evidence of cerebral axonopathy in patients with “pure” adrenomyeloneuropathy
Dubey, P., Fatemi, A. S., Barker, P. B., Degaonkar, M. N., Tröger, M., Zackowski, K. M., Bastian, A. J., Smith, S. A., Pomper, M. G., Moser, H. W., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000149514.13580.84 · Cited by 45
Self-citationPeroxisomal Disorders: A Review on Cerebellar Pathologies
Munter, S. D., Verheijden, S., Régal, L., & Baes, M. I. (2015) · Brain Pathology · doi:10.1111/bpa.12290 · Cited by 46
Motor neuron involvement in anti-Ma2-associated paraneoplastic neurological syndrome
Vogrig, A., Joubert, B., Maureille, A., Thomas, L., Bernard, E., Streichenberger, N., Cotton, F., Ducray, F., & Honnorat, J. (2018) · Journal of Neurology · doi:10.1007/s00415-018-9143-x · Cited by 43
Perlman, S. J., & Mar, S. (2012) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-0653-2_13 · Cited by 43
MRI evaluation of pathologies affecting the corpus callosum: A pictorial essay
Kazi, A., Joshi, P., Kelkar, A., Mahajan, M., & Ghawate, A. S. (2013) · Indian journal of radiology and imaging - new series/Indian journal of radiology and imaging/Indian Journal of Radiology & Imaging · doi:10.4103/0971-3026.125604 · Cited by 42
Chiesa, R., Boelens, J. J., Duncan, C., Kühl, J., Sevin, C., Kapoor, N., Prasad, V. K., Lindemans, C. A., Jones, S. A., Amartino, H. M., et al. (2021) · Blood Advances · doi:10.1182/bloodadvances.2021005294 · Cited by 41
Self-citationDiffusion tensor–based imaging reveals occult abnormalities in adrenomyeloneuropathy
Dubey, P., Fatemi, A., Huang, H., Nagae‐Poetscher, L., Wakana, S., Barker, P. B., van Zijl, P., Moser, H. W., Mori, S., & Raymond, G. V. (2005) · Annals of Neurology · doi:10.1002/ana.20643 · Cited by 40
Self-citationvan Hasselt, P. M., & Boelens, J. J. (2016) · Neuropediatrics · doi:10.1055/s-0036-1584602 · Cited by 40
Chitotriosidase as a biomarker of cerebral adrenoleukodystrophy
Orchard, P. J., Lund, T. C., Miller, W., Rothman, S. M., Raymond, G. V., Nascene, D. R., Basso, L. M., Cloyd, J. C., & Tolar, J. (2011) · Journal of Neuroinflammation · doi:10.1186/1742-2094-8-144 · Cited by 39
Self-citationClinical and radiographic course of arrested cerebral adrenoleukodystrophy
Mallack, E. J., van de Stadt, S. I. W., Caruso, P. A., Musolino, P. L., Sadjadi, R., Engelen, M., & Eichler, F. (2020) · Neurology · doi:10.1212/wnl.0000000000009626 · Cited by 39
Hypoperfusion predicts lesion progression in cerebral X-linked adrenoleukodystrophy
Musolino, P. L., Rapalino, O., Caruso, P., Caviness, V. S., & Eichler, F. S. (2012) · Brain · doi:10.1093/brain/aws206 · Cited by 37
Imaging Manifestations of the Leukodystrophies, Inherited Disorders of White Matter
Yang, E., & Prabhu, S. P. (2014) · Radiologic Clinics of North America · doi:10.1016/j.rcl.2013.11.008 · Cited by 35
Newborn Screening for X-Linked Adrenoleukodystrophy: Review of Data and Outcomes in Pennsylvania
Priestley, J. R. C., Adang, L. A., Drewes Williams, S., Lichter-Konecki, U., Menello, C., Engelhardt, N. M., DiPerna, J. C., DiBoscio, B., Ahrens-Nicklas, R. C., Edmondson, A. C., et al. (2022) · International Journal of Neonatal Screening · doi:10.3390/ijns8020024 · Cited by 35
Inborn Errors of Metabolism: Combining Clinical and Radiologic Clues to Solve the Mystery
Ibrahim, M., Parmar, H. A., Hoefling, N., & Srinivasan, A. (2014) · American Journal of Roentgenology · doi:10.2214/ajr.13.11154 · Cited by 34
Stromillo, M. L., Dotti, M. T., Battaglini, M., Mortilla, M., Bianchi, S., Plewnia, K., Pantoni, L., Inzitari, D., Federico, A., & Stefano, N. D. (2008) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2008.155853 · Cited by 33
Phenotypic spectrum of mutations in IBA57 , a candidate gene for cavitating leukoencephalopathy
Liu, M., Zhang, J., Zhang, Z., Zhou, L., Jiang, Y. Z., Wang, J., Xiao, J., & Wu, Y. (2017) · Clinical Genetics · doi:10.1111/cge.13090 · Cited by 33
Bone marrow transplantation in patients with storage diseases: a developing country experience
Lange, M. C., Teive, H. A. G., Troiano, A. R., Bitencourt, M. A., Funke, V. A. M., Setubal, D. C., Neto, J. Z., de Medeiros, C. R., Werneck, L. C., Pasqüini, R., et al. (2006) · Arquivos de Neuro-Psiquiatria · doi:10.1590/s0004-282x2006000100001 · Cited by 33
Cell therapy for diverse central nervous system disorders: inherited metabolic diseases and autism
Sun, J. M., & Kurtzberg, J. (2017) · Pediatric Research · doi:10.1038/pr.2017.254 · Cited by 31
Adrénoleucodystrophie liée à l'X
Aubourg, P. R. (2007) · Annales d Endocrinologie · doi:10.1016/j.ando.2007.04.002 · Cited by 33
Topical Review: Neuroimaging in Leukodystrophies
Barker, P. B., & Horská, A. (2004) · Journal of Child Neurology · doi:10.1177/088307380401900801 · Cited by 30
Krishna, S. H., McKinney, A. M., & Lucato, L. T. (2013) · Seminars in Ultrasound CT and MRI · doi:10.1053/j.sult.2013.10.008 · Cited by 29
Imaging in X-Linked Adrenoleukodystrophy
van de Stadt, S. I. W., Huffnagel, I. C., Turk, B. R., van der Knaap, M. S., & Engelen, M. (2021) · Neuropediatrics · doi:10.1055/s-0041-1730937 · Cited by 30
Neurometabolic diseases of childhood
Patay, Z. J., Blasér, S., Poretti, A., & Huisman, T. A. G. M. (2015) · Pediatric Radiology · doi:10.1007/s00247-015-3279-y · Cited by 28
Bonaventura, E., Alberti, L., Lucchi, S., Cappelletti, L., Fazzone, S., Cattaneo, E., Bellini, M., Izzo, G., Parazzini, C., Bosetti, A., et al. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2022.1072256 · Cited by 27
Spinal cord involvement in adult-onset metabolic and genetic diseases
Marelli, C., Salsano, E., Politi, L. S., & Labauge, P. M. (2018) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2018-318666 · Cited by 27
A neuroimaging approach to inborn errors of metabolism
Blasér, S., & Feigenbaum, A. J. (2004) · Neuroimaging Clinics of North America · doi:10.1016/j.nic.2004.03.013 · Cited by 27
Antioxidant Capacity and Superoxide Dismutase Activity in Adrenoleukodystrophy
Turk, B. R., Theisen, B. E., Nemeth, C. L., Marx, J. S., Shi, X., Rosen, M. H., Jones, R. O., Moser, A. B., Watkins, P. A., Raymond, G. V., et al. (2017) · JAMA Neurology · doi:10.1001/jamaneurol.2016.5715 · Cited by 27
Self-citationDiagnostic approach in adult-onset neurometabolic diseases
Fernández‐Eulate, G., Carreau, C., Benoist, J., Lamari, F., Rucheton, B., Shor, N., & Nadjar, Y. (2022) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2021-328045 · Cited by 28
Ayrignac, X., Dalliere, C. C., Marelli, C., Taïeb, G., & Labauge, P. M. (2022) · JAMA Neurology · doi:10.1001/jamaneurol.2022.2141 · Cited by 25
van den Dorpel, J. J. A., Mackenbach, M. J., Dremmen, M. H. G., van der Vlugt, W. M. C., Rizopoulos, D., van Doorn, P. A., van der Ploeg, A. T., Muetzel, R. L., van der Beek, N. A. M. E., & van den Hout, J. M. P. (2024) · Journal of Inherited Metabolic Disease · doi:10.1002/jimd.12736 · Cited by 24
Therapeutic strategies in adrenoleukodystrophy
Turk, B. R., Moser, A. B., & Fatemi, A. S. (2017) · Wiener Medizinische Wochenschrift · doi:10.1007/s10354-016-0534-2 · Cited by 24
Self-citationNewborn Screening and Emerging Therapies for X-Linked Adrenoleukodystrophy
Moser, A. B., & Fatemi, A. (2018) · JAMA Neurology · doi:10.1001/jamaneurol.2018.1585 · Cited by 22
Self-citationNeurocognitive benchmarks following transplant for emerging cerebral adrenoleukodystrophy
Pierpont, E. I., Nascene, D. R., Shanley, R., Kenney-Jung, D. L., Ziegler, R. S., Miller, W. P., Gupta, A. O., Lund, T. C., Orchard, P. J., & Eisengart, J. B. (2020) · Neurology · doi:10.1212/wnl.0000000000009929 · Cited by 21
The effect of bone marrow transplantation on oxidative stress in X-linked adrenoleukodystrophy
Rockenbach, F. J., Deon, M., Marchese, D. P., Manfredini, V., Mescka, C. P., Ribas, G. S., Habekost, C. T., de Castro, C. G., Jardim, L. B., & Vargas, C. R. (2012) · Molecular Genetics and Metabolism · doi:10.1016/j.ymgme.2012.03.019 · Cited by 21
(2006) · Springer eBooks · doi:10.1007/3-540-29623-9_9160 · Cited by 21
X‐linked adrenoleukodystrophy with olivopontocerebellar atrophy
Vianello, M., Manara, R., Betterle, C., Tavolato, B. F., Mariniello, B., & Giometto, B. (2005) · European Journal of Neurology · doi:10.1111/j.1468-1331.2005.01134.x · Cited by 21
Sąsiadek, M. J. (2015) · Polish Journal of Radiology · doi:10.12659/pjr.893285 · Cited by 20
Spinocerebellar variant of adrenoleukodystrophy with a novel ABCD1 gene mutation
Li, J.-Y., Hsu, C., & Tsai, C. (2009) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2009.12.002 · Cited by 22
Brain fluorodeoxyglucose PET in adrenoleukodystrophy
Salsano, E., Marotta, G., Manfredi, V., Gıovagnolı, A. R., Farina, L., Savoiardo, M., Pareyson, D., Benti, R., & Uziel, G. (2014) · Neurology · doi:10.1212/wnl.0000000000000770 · Cited by 18
Capecitabine-induced leukoencephalopathy involving the bilateral corticospinal tracts
Tan, M. B., & McAdory, L. E. (2016) · Journal of Radiology Case Reports · doi:10.3941/jrcr.v10i3.2686 · Cited by 18
“Barbell Sign”: A Diagnostic Imaging Finding in Progressive Multifocal Leukoencephalopathy
Bezuidenhout, A. F., Andronikou, S., Ackermann, C., du Plessis, A., Basson, D. J., & Bhadelia, R. A. (2018) · Journal of Computer Assisted Tomography · doi:10.1097/rct.0000000000000719 · Cited by 18
Correlation of Neurodevelopmental Features and MRI Findings in Infantile Krabbe's Disease
Provenzale, J. M., Peddi, S., Kurtzberg, J., Poe, M. D., Mukundan, S., & Escolar, M. L. (2008) · American Journal of Roentgenology · doi:10.2214/ajr.07.3885 · Cited by 18
Unmasking adrenoleukodystrophy in a cohort of cerebellar ataxia
Chen, Y., Lee, Y., Tsai, Y., Guo, Y., Hsiao, C.-T., Tsai, P., Huang, J., Liao, Y., & Soong, B. (2017) · PLoS ONE · doi:10.1371/journal.pone.0177296 · Cited by 18
Presymptomatic Lesion in Childhood Cerebral Adrenoleukodystrophy
Mallack, E. J., van Haren, K. P., Torrey, A. C., van de Stadt, S. I. W., Engelen, M., Raymond, G. V., Fatemi, A. S., & Eichler, F. (2022) · Neurology · doi:10.1212/wnl.0000000000200571 · Cited by 17
Self-citationDing, X. Q., Wittkugel, O., Goebell, E., Förster, A., Grzyska, U., Zeumer, H., & Fiehler, J. (2007) · European Journal of Paediatric Neurology · doi:10.1016/j.ejpn.2007.08.012 · Cited by 17
Evaluation of Therapy of X-Linked Adrenoleukodystrophy
Moser, H. W., Fatemi, A. S., Zackowski, K. M., Smith, S., Golay, X., Muenz, L. R., & Raymond, G. V. (2004) · Neurochemical Research · doi:10.1023/b:nere.0000021245.12181.90 · Cited by 17
Self-citationAccuracy of Conventional MRI in ALS
Gupta, A., Nguyen, T., Chakraborty, S., & Bourque, P. R. (2014) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100016267 · Cited by 17
Post‐transplant adaptive function in childhood cerebral adrenoleukodystrophy
Pierpont, E. I., McCoy, E., King, K. E., Ziegler, R. S., Shanley, R., Nascene, D. R., Raymond, G. V., Phelan, R., Lund, T. C., Orchard, P. J., et al. (2018) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.526 · Cited by 16
Self-citationClinical and Neuroimaging Spectrum of Peroxisomal Disorders
Tan, A. P., Gonçalves, F. G., Almehdar, A., & Soares, B. P. (2018) · Topics in Magnetic Resonance Imaging · doi:10.1097/rmr.0000000000000172 · Cited by 16
Cognitive Functions in Adult‐Onset Phenotypes of X‐Linked Adrenoleukodystrophy
Schäfer, L., Roicke, H., Fischer, M., Sühnel, A., & Köhler, W. (2021) · Annals of Neurology · doi:10.1002/ana.26141 · Cited by 16
Trompier, D., & Savary, S. (2013) · Colloquium Series on The Genetic Basis of Human Disease · doi:10.4199/c00075ed1v01y201303gbd004 · Cited by 17
Waldman, A. T. (2018) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000000560 · Cited by 16
Turk, B. R., Theda, C., Fatemi, A. S., & Moser, A. B. (2019) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2019.11.002 · Cited by 17
Self-citationWarren, D., Connolly, D. J. A., Wilkinson, I. D., Sharrard, M. J., & Griffiths, P. D. (2007) · Developmental Medicine & Child Neurology · doi:10.1111/j.1469-8749.2007.00135.x · Cited by 16
Efferent and afferent evoked potentials in patients with adrenomyeloneuropathy
Matsumoto, H., Hanajima, R., Terao, Y., Hamada, M., Yugeta, A., Shirota, Y., Yuasa, K., Satō, F., Matsukawa, T., Takahashi, Y., et al. (2009) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2009.11.005 · Cited by 15
Prominent brain axonal damage and functional reorganization in “pure” adrenomyeloneuropathy
Marino, S., Luca, M. D., Dotti, M., Stromillo, M., Formichi, P., Galluzzi, P., Mondelli, M., Bramanti, P., Federico, A., & de Stefano, N. (2007) · Neurology · doi:10.1212/01.wnl.0000276945.92950.69 · Cited by 13
Kang, J. W., Lee, S. M., Koo, K. Y., Lee, Y., Nam, H. S., Quan, Z., & Kang, H. (2014) · Yonsei Medical Journal · doi:10.3349/ymj.2014.55.4.1157 · Cited by 15
Leukodystrophy: Basic and Clinical
Raymond, G. V. (2017) · Advances in neurobiology · doi:10.1007/978-3-319-57193-5_14 · Cited by 15
Self-citationMR Imaging of Midbrain Pathologies
Hattingen, E., Blasel, S., Nichtweiß, M., Zanella, F., & Weidauer, S. (2010) · Clinical Neuroradiology · doi:10.1007/s00062-010-0009-6 · Cited by 15
Metadata
- Authors
- Loes, D. J., Fatemi, A., Melhem, E. R., Gupte, N., Bezman, L., Moser, H. W., & Raymond, G. V.
- Affiliations
- Kennedy Krieger Institute (US)
- Venue
- Neurology
- Published
- 2003-08-12
- Volume
- 61
- Issue
- 3
- Pages
- 369-374
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2151567647
- Cited by
- 268
- References
- 25
- Citations by year
- 2026: 11 · 2025: 16 · 2024: 12 · 2023: 13 · 2022: 17 · 2021: 15 · 2020: 14 · 2019: 13 · 2018: 15 · 2017: 17 · 2016: 14 · 2015: 9 · 2014: 13 · 2013: 9 · 2012: 13
- FWCI
- 4.51
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. National Library of Medicine (LM9-3537)
- National Center for Research Resources (M0RR11)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD-10981, P01HD010981)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Clinical Biochemistry › Metabolism and Genetic Disorders
- Health Sciences › Medicine › Genetics (clinical) › Lysosomal Storage Disorders Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Genetic Neurodegenerative Diseases
- Keywords
- X-linked adrenoleukodystrophy, cerebral adrenoleukodystrophy, disease progression prediction, T2 hyperintensity, white matter lesions, corticospinal tract, cerebellar white matter, patient age
- MeSH terms
- Adolescent, Adrenoleukodystrophy, Adult, Age Factors, Aged, Child, Child, Preschool, Drug Combinations, Erucic Acids, Follow-Up Studies, Humans, Image Processing, Computer-Assisted, Infant, Magnetic Resonance Imaging, Male, Middle Aged, Predictive Value of Tests, Prognosis, Severity of Illness Index, Triolein, Linear Models, Disease Progression
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
