The DOI matches its Crossref record, with a small difference in title or year; 13 of the 14 references it cites were found in a registry or an index.
Estimating risk for developing epilepsy: A population-based study in Rochester, Minnesota
Open accessAbstract
OBJECTIVES: Previous studies that have assessed the risk of developing epilepsy have failed to account for the competing risk of death, significant in the elderly where epilepsy incidence is highest. We report the lifetime risk for epilepsy, accounting for the competing risk of mortality. METHODS: Lifetime risk and cumulative incidence of epilepsy were examined among Rochester, MN, residents between 1960 and 1979. Age-, gender-, and calendar year-specific deaths were obtained for Rochester, MN. Lifetime risk was calculated as the conditional probability of developing epilepsy by a specific age for a person reaching that age who had not yet developed epilepsy. Lifetime risk and cumulative incidence were compared for age and time period. RESULTS: We identified 412 individuals with incident epilepsy diagnosed between January 1, 1960, and December 31, 1979. Lifetime risk was 1.6% to age 50 and 3.0% to age 80; cumulative incidence was 1.7% to age 50 and 3.4% to age 80. Similar differences were seen across epilepsy etiologies. Lifetime risk through 87 years of age increased over time from 3.5% in 1960-1969 to 4.2% in 1970-1979. CONCLUSIONS: One in 26 people will develop epilepsy during their lifetime. Lifetime risk provides an estimate of an individual's risk for epilepsy over his or her remaining lifetime, translates into the number of people who are expected to develop epilepsy, and assists health care planners as they estimate service needs for epilepsy.
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“It is a common comorbidity after TBI, and TBI is known as a leading cause of adulthood epilepsy [6,7].”
From Impact of a Prison-Based Religious Program on Mental Health State and Aggression Level Among Female Inmates (2019) · cites this paper as [6]
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Metadata
- Authors
- Hesdorffer, D. C., Logroscino, G., Benn, E. K. T., Katri, N., Cascino, G., & Hauser, W. A.
- Affiliations
- Mayo Clinic (US)
- Venue
- Neurology
- Published
- 2011-01-04
- Volume
- 76
- Issue
- 1
- Pages
- 23-27
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- PMC
- PMC3032191
- OpenAlex
- W2064064788
- Cited by
- 324
- References
- 14
- Citations by year
- 2026: 18 · 2025: 18 · 2024: 20 · 2023: 25 · 2022: 22 · 2021: 34 · 2020: 24 · 2019: 20 · 2018: 22 · 2017: 23 · 2016: 26 · 2015: 19 · 2014: 17 · 2013: 9 · 2012: 17
- FWCI
- 7.74
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Neurology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Pfizer
- Association of American Medical Colleges
- University of Minnesota
- NeuroPace
- Ministero della Salute
- H. Lundbeck A/S
- National Institutes of Health (NS043209)
- Centers for Disease Control and Prevention (DP002209)
- National Institute of Neurological Disorders and Stroke (NS043209, T32NS007153, NS07153, P50NS016308)
- National Center for Research Resources (MO1 RR00645, M01RR000645)
- Maternal and Child Health Bureau
- Topics
- Health Sciences › Medicine › Clinical Neurology › Epilepsy research and treatment
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Epidemiology
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmacological Effects and Toxicity Studies
- Keywords
- epilepsy, lifetime risk, cumulative incidence, competing risk of death, older adults, Rochester, Minnesota, epilepsy etiology, health planning
- MeSH terms
- Age Factors, Aged, Aged, 80 and over, Epilepsy, Female, Humans, Male, Middle Aged, Minnesota, Predictive Value of Tests, Probability, Retrospective Studies, Risk Factors, Sex Factors, Incidence, Community Health Planning
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