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Effect of serotonin in migraine patients

Open access
Kimball, Robert W., Friedman, Arnold P., Vallejo, Edward·1960·Neurology

Abstract

EFFECT OF SEROTONIN IN MIGRAINE PATIENTS Robert W. Kimball, Arnold P. Friedman, and Edward Vallejo Neurology 1960;10:107–111 Little is known of the factors that predispose to migraine or the biochemical events that initiate the disturbances characteristic of this condition. Earlier studies by Marcussen and Wolff have shown that an initial phase of vasoconstriction is responsible for the prodromal symptoms, while the pain follows a marked distention of cranial vessels that are temporarily hypotonic. They also have presented certain evidence which presumably indicates that a pain threshold-lowering substance renders the distention of the large arteries painful. However, alteration in tone, lumen, and pain threshold of the arteries alone cannot explain the complex symptomatology of the migraine attack.

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Metadata

Authors
Kimball, R. W., Friedman, A. P., & Vallejo, E.
Venue
Neurology
Published
1960-02
Volume
10
Issue
2
Pages
107-107
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2078596134
Cited by
247
References
0
FWCI
8.33
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Effect of serotonin in migraine patients. https://app.cochat.ai/papers/10.1212/wnl.10.2.107
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Kimball, R. W., Friedman, A. P., & Vallejo, E. (1960). Effect of serotonin in migraine patients. Neurology. https://doi.org/10.1212/wnl.10.2.107

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.