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Unexpected, unexplained death in epileptic patients
Abstract
Thirty-seven cases of unexpected, unexplained death in epileptic patients were recorded by the Allegheny County Coroner's Office during the years 1969 through 1973. In no case was there anatomic or chemical evidence at autopsy sufficient to explain death. All patients had a duration of epilepsy greater than a year. All but two had less than one seizure per month. Blood levels of anticonvulsants at autopsy revealed only three patients with therapeutic levels of the drugs. Almost 50 percent of the cases studied had no demonstrable anticonvulsant. It is suggested that inadequate levels of anticonvulsant drugs are a significant factor associated with unexpected, unexplained death in epileptic patients.
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Cited by
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BENARROCH, E. E. (1993) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(12)62272-1 · Cited by 1,534
Cardiovascular effects of human insular cortex stimulation
Oppenheimer, S. M., Gelb, A., Girvin, J. P., & Hachinski, V. C. (1992) · Neurology · doi:10.1212/wnl.42.9.1727 · Cited by 1,272
Unifying the definitions of sudden unexpected death in epilepsy
Nashef, L., So, E. L., Ryvlin, P., & Tomson, T. (2012) · Epilepsia · doi:10.1111/j.1528-1167.2011.03358.x · Cited by 632
Risk factors for sudden unexpected death in epilepsy: a case control study
Nilsson, L., Farahmand, B., Persson, P.-G., Thiblin, I., & Tomson, T. (1999) · The Lancet · doi:10.1016/s0140-6736(98)05114-9 · Cited by 522
Sudden Unexpected Death in Epilepsy: A Review of Incidence and Risk Factors
Tomson, T., Walczak, T., Sillanpaa, M., & Sander, J. W. A. S. (2005) · Epilepsia · doi:10.1111/j.1528-1167.2005.00411.x · Cited by 355
Metadata
- Authors
- TERRENCE, C. F., WISOTZKEY, H. M., & PERPER, J. A.
- Venue
- Neurology
- Published
- 1975-06
- Volume
- 25
- Issue
- 6
- Pages
- 594-594
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2057928102
- Cited by
- 185
- References
- 0
- FWCI
- 1.46
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Unexpected, unexplained death in epileptic patients. https://app.cochat.ai/papers/10.1212/wnl.25.6.594
- The paper
- TERRENCE, C. F., WISOTZKEY, H. M., & PERPER, J. A. (1975). Unexpected, unexplained death in epileptic patients. Neurology. https://doi.org/10.1212/wnl.25.6.594
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
