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The Harvard Cooperative Stroke Registry: A prospective registry

Open access
Mohr, J. P., Caplan, Louis R., Melski, John W., Goldstein, Robert J., Duncan, Gary W., Kistler, J. P., Pessin, Michael S., Bleich, Howard L.·1978·Neurology

Abstract

Data from 694 patients hospitalized with stroke were entered in a prospective, computer-based registry. Three hundred and sixty-four patients (53 percent) were diagnosed as having thrombosis, 215 (31 percent)as having cerebral embolism 70 (10 percent) as having intracerebral hematoma, and 45 (6 percent) as having subarachnoid hemorrhage from aneurysm or arteriovenous malformations. The 364 patients diagnosed as having thrombosis were divided into 233 (34 percent of all 694 patients) whose thrombosis was thought to involve a large artery and 131 (19 percent) with lacunar infarction. Many of the findings in this study were comparable to those in previous registries based on postmortem data. New observations include the high incidence of lacunes and cerebral emboli, the absence of an identifiable cardiac origin in 37 percent of all emboli, a nonsudden onset in 21 percent of emboli, and the occurrence of vomiting at onset in 51 percent and the absence of headache at onset in 67 percent of hematomas.

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Metadata

Authors
Mohr, J. P., Caplan, L. R., Melski, J. W., Goldstein, R. J., Duncan, G. W., Kistler, J. P., Pessin, M. S., & Bleich, H. L.
Venue
Neurology
Published
1978-08
Volume
28
Issue
8
Pages
754-754
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2129898996
Cited by
1,172
References
1
FWCI
11.69
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Harvard Cooperative Stroke Registry: A prospective registry. https://app.cochat.ai/papers/10.1212/wnl.28.8.754
The paper
Mohr, J. P., Caplan, L. R., Melski, J. W., Goldstein, R. J., Duncan, G. W., Kistler, J. P., Pessin, M. S., & Bleich, H. L. (1978). The Harvard Cooperative Stroke Registry: A prospective registry. Neurology. https://doi.org/10.1212/wnl.28.8.754

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