The DOI matches its Crossref record.
Cerebral blood flow and cerebrovascular CO 2 reactivity in stroke‐age normal controls
Abstract
We used the noninvasive 133-xenon inhalation technique to determine cerebral hemodynamics in 55 normal volunteers aged 18 to 88. Values for cerebral blood flow and cerebrovascular CO2 reactivity in fast-clearing tissue (flow gray) and slow-clearing tissue (flow white) were examined as functions of age and in relation to hematocrit, blood pressure, and evidence of extracranial vascular disease. Flow gray declined linearly with age, but no corresponding change was found in flow white or in CO2 reactivity. The data suggest that the progressive fall in flow gray is due to a physiologic aging process.
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Citations
Cited by
Adverse Cerebral Outcomes after Coronary Bypass Surgery
Roach, G. W., Kanchuger, M., Mangano, C. M., Newman, M., Nussmeier, N., Wolman, R., Aggarwal, A., Marschall, K., Graham, S. H., Ley, C., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612193352501 · Cited by 1,860
Estrogen as a Neuroprotectant in Stroke
Hurn, P. D., & Macrae, I. M. (2000) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200004000-00001 · Cited by 401
Regional cerebral blood flow and oxygen consumption in human aging
Pantano, P., Baron, J. C., Lebrun-Grandié, P., Duquesnoy, N., Bousser, M. G., & Comar, D. (1984) · Stroke · doi:10.1161/01.str.15.4.635 · Cited by 341
Schöning, M., Walter, J., & Scheel, P. (1994) · Stroke · doi:10.1161/01.str.25.1.17 · Cited by 299
Murrell, C. J., Cotter, J. D., Thomas, K. N., Lucas, S. J. E., Williams, M. J. A., & Ainslie, P. N. (2013) · AGE · doi:10.1007/s11357-012-9414-x · Cited by 207
Metadata
- Authors
- Davis, S. M., Ackerman, R. H., Correia, J. A., Alpert, N. M., Chang, J., Buonanno, F., Kelley, R. E., Rosner, B., & Taveras, J. M.
- Venue
- Neurology
- Published
- 1983-04
- Volume
- 33
- Issue
- 4
- Pages
- 391-391
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W1973051454
- Cited by
- 161
- References
- 0
- FWCI
- 5.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Cerebral blood flow and cerebrovascular CO 2 reactivity in stroke‐age normal controls. https://app.cochat.ai/papers/10.1212/wnl.33.4.391
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- Davis, S. M., Ackerman, R. H., Correia, J. A., Alpert, N. M., Chang, J., Buonanno, F., Kelley, R. E., Rosner, B., & Taveras, J. M. (1983). Cerebral blood flow and cerebrovascular CO 2 reactivity in stroke‐age normal controls. Neurology. https://doi.org/10.1212/wnl.33.4.391
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
