The DOI matches its Crossref record.
Decreased cerebral blood flow precedes multi‐infarct dementia, but follows senile dementia of Alzheimer type
Abstract
A 7-year prospective study among 181 neurologically normal elderly volunteers (mean age, 70.6 years) revealed an incidence of 3.3%, or 0.47% new cases per year, for Alzheimer's disease (SDAT) and 5.5%, or 0.78% new cases per year, for multi-infarct dementia (MID). The unusually high incidence of MID is considered to reflect preselection of a large percentage of volunteers (48.6%) with risk factors for (but without symptoms of) atherothrombotic stroke. Of 88 volunteers at risk of stroke, 11.4% developed MID within 7 years. In MID patients, cerebral blood flow (CBF) values began to decline around 2 years before onset of symptoms, while in SDAT patients, CBF levels remained normal until symptoms of dementia appeared; thereafter, CBF declined rapidly.
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Cited by
Forette, F., Seux, M.-L., Staessen, J. A., Thijs, L., Birkenhäger, W. H., Babarskiene, M.-R., Babeanu, S., Bossini, A., Gil-Extremera, B., Girerd, X., et al. (1998) · The Lancet · doi:10.1016/s0140-6736(98)03086-4 · Cited by 1,441
Young, B. G., Jordan, K. G., & Doig, G. S. (1996) · Neurology · doi:10.1212/wnl.47.1.83 · Cited by 668
The occult aftermath of boxing.
Roberts, G. W., Allsop, D., & Bruton, C. (1990) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.53.5.373 · Cited by 518
Senile Dementia of the Binswanger Type: A Vascular Form of Dementia in the Elderly
Román, G. C. (1987) · JAMA · doi:10.1001/jama.1987.03400130096040 · Cited by 372
Zesiewicz, T. A., Elble, R., Louis, E. D., Hauser, R. A., Sullivan, K. L., Dewey, R. B., Ondo, W. G., Gronseth, G. S., & Weiner, W. J. (2005) · Neurology · doi:10.1212/01.wnl.0000163769.28552.cd · Cited by 371
Metadata
- Authors
- Rogers, R. L., Meyer, J. S., Mortel, K. F., Mahurin, R. K., & Judd, B. W.
- Venue
- Neurology
- Published
- 1986-01
- Volume
- 36
- Issue
- 1
- Pages
- 1-1
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2088856242
- Cited by
- 218
- References
- 0
- FWCI
- 10.93
- Type
- journal article
- Language
- en
- Open access
- closed
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- Rogers, R. L., Meyer, J. S., Mortel, K. F., Mahurin, R. K., & Judd, B. W. (1986). Decreased cerebral blood flow precedes multi‐infarct dementia, but follows senile dementia of Alzheimer type. Neurology. https://doi.org/10.1212/wnl.36.1.1
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
