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Cited by 174Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments

The DOI matches its Crossref record.

Periventricular white matter lucencies in senile dementia of the Alzheimer type and in normal aging

Rezek, Donald L., Morris, John C., Fulling, Keith H., Gado, Mokhtar H.·1987·Neurology
DOI 10.1212/wnl.37.8.1365
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Abstract

The significance of periventricular lucencies in the white matter on CT in demented patients is not understood. We studied the relationship of these changes to mental status of subjects with senile dementia of the Alzheimer type. A semiquantitative method showed more numerous and extensive lucencies in demented than in healthy elderly. Neuropathologic examination of five subjects with these changes and confirmed Alzheimer's disease revealed diffuse white matter pallor without infarction. There were no hypertensive vascular changes, although limited hyaline thickening was present.

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Metadata

Authors
Rezek, D. L., Morris, J. C., Fulling, K. H., & Gado, M. H.
Affiliations
Washington University in St. Louis (US)
ORCID
Morris, John C.
Venue
Neurology
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
1987-08
Volume
37
Issue
8
Pages
1365-1365
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
DOI
10.1212/wnl.37.8.1365
OpenAlex
W2136432656
Cited by
173
References
0
Citations by year
2025: 1 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 1 · 2016: 1 · 2015: 4 · 2014: 1 · 2013: 1
FWCI
14.04
Type
journal article
Language
en
Open access
closed
Locations
  • Neurology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5t32ns007205-32)
  • National Institute on Aging (P01 AG0 3991, P01AG003991)
  • National Institute of Neurological Disorders and Stroke (5 T32 NS07205-04)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
  • Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
Keywords
senile dementia of the Alzheimer type, Alzheimer's disease, normal aging, mental status, head CT, neuropathology
MeSH terms
Aged, Aging, Alzheimer Disease, Brain, Cerebral Ventricles, Female, Humans, Longitudinal Studies, Male, Tomography, X-Ray Computed

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