Cited by 95Cardiovascular Syncope and Autonomic DisordersCerebrovascular and Carotid Artery DiseasesAcute Ischemic Stroke Management

Orthostatic hypotension as a risk factor for symptomatic occlusive cerebrovascular disease

Dobkin, Bruce H.·1989·Neurology

Abstract

Thirteen patients presented with brief, repetitive, stereotyped transient ischemic attacks, large artery atherostenoses or occlusions with impaired collateral flow to a cortical perfusion borderzone, and orthostatic hypotension (OH). OH was caused by diabetes mellitus, aging, and treatments for ischemic heart disease and hypertension. Medical management of OH often eliminated the need for stroke prevention measures such as surgery or anticoagulation. Focal cerebral hypoperfusion from the combination of occlusive vascular disease and OH may be an underreported, treatable cause of TIA and stroke.

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Crossref · 10.1212/wnl.39.1.30

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  • Orthostatic TIAs concern a combination of multiple stenoses of cerebral arteries and OH, and may rarely result in repetitive, orthostatic, short-lasting, and stereotyped TIAs.

    “An exception concerns orthostatic TIAs , concerning a combination of multiple stenoses of cerebral arteries and OH. This may rarely result in repetitive, orthostatic, short-lasting, and stereotyped TIAs.”

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Authors
Dobkin, B. H.
Affiliations
University of California, Los Angeles (US)
Corresponding author
Dobkin, Bruce H.
Venue
Neurology
Published
1989-01
Volume
39
Issue
1
Pages
30-30
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2075153221
Cited by
95
References
0
Citations by year
2024: 2 · 2023: 1 · 2022: 1 · 2020: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 5 · 2013: 3 · 2012: 1
FWCI
6.36
Type
journal article
Language
en
Open access
closed
Locations
  • Neurology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cerebrovascular and Carotid Artery Diseases
  • Health Sciences › Medicine › Epidemiology › Acute Ischemic Stroke Management
Keywords
orthostatic hypotension, transient ischemic attack, stroke, cerebral ischemia, large artery atherosclerosis, collateral circulation, diabetes mellitus, stroke prevention, antihypertensive drugs
MeSH terms
Arterial Occlusive Diseases, Carotid Artery Diseases, Cerebral Angiography, Ischemic Attack, Transient, Cerebrovascular Disorders, Constriction, Pathologic, Female, Humans, Hypotension, Orthostatic, Middle Aged, Risk Factors, Tomography, X-Ray Computed, Diabetes Complications

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