The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Correlation of magnetic resonance imaging with neuropsychological testing in multiple sclerosis
Open accessAbstract
Previous research has suggested that cerebral lesions observed on magnetic resonance imaging (MRI) of MS patients are clinically "silent." We examined the validity of this assertion by correlating neuropsychological test performance with MRI findings in 53 MS patients. We used a semiautomated quantitation system to measure three MRI variables: total lesion area (TLA), ventricular-brain ratio (VBR), and size of the corpus callosum (SCC). Stepwise multiple regression analyses indicated that TLA was a robust predictor of cognitive dysfunction, particularly for measures of recent memory, abstract/conceptual reasoning, language, and visuospatial problem solving. SCC predicted test performance on measures on mental processing speed and rapid problem solving, while VBR did not independently predict cognitive test findings. These findings suggest that cerebral lesions in MS produce cognitive dysfunction and that MRI may be a useful predictor of cognitive dysfunction.
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Cited by
Cognitive impairment in multiple sclerosis
Chiaravalloti, N. D., & DeLuca, J. (2008) · The Lancet Neurology · doi:10.1016/s1474-4422(08)70259-x · Cited by 2,088
White Matter Changes in Schizophrenia: Evidence for Myelin-Related Dysfunction
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Learmonth, Y. C., Motl, R. W., Sandroff, B. M., Pula, J. H., & Cadavid, D. (2013) · BMC Neurology · doi:10.1186/1471-2377-13-37 · Cited by 773
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Metadata
- Authors
- Rao, S. M., Leo, G. J., Haughton, V. M., Aubin-Faubert, P. S., & Bernardin, L.
- Venue
- Neurology
- Published
- 1989-02
- Volume
- 39
- Issue
- 2
- Pages
- 161-161
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2017381757
- Cited by
- 516
- References
- 5
- FWCI
- 12.63
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Rao, S. M., Leo, G. J., Haughton, V. M., Aubin-Faubert, P. S., & Bernardin, L. (1989). Correlation of magnetic resonance imaging with neuropsychological testing in multiple sclerosis. Neurology. https://doi.org/10.1212/wnl.39.2.161
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