The DOI matches its Crossref record.
Initial bolus of conventional versus high‐dose dexamethasone in metastatic spinal cord compression
Abstract
We randomly assigned dexamethasone in an initial bolus of 10 mg IV or 100 mg IV followed by 16 mg daily orally to 37 patients with metastatic spinal cord compression. The average pain score before the start of treatment was 5.2 (SD = 2.8) and decreased significantly (p less than 0.001) to 3.8 at 3 hrs, 2.8 at 24 hrs, and 1.4 after 1 week. There were no differences between the conventional and high-dose group on pain, ambulation, or bladder function.
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Citations
Cited by
Loblaw, D. A., Perry, J., Chambers, A., & Laperriere, N. J. (2005) · Journal of Clinical Oncology · doi:10.1200/jco.2005.00.067 · Cited by 325
Heimdal, K., Hirschberg, H., Sletteb�, H., Watne, K., & Nome, O. (1992) · Journal of Neuro-Oncology · doi:10.1007/bf00172664 · Cited by 173
Metadata
- Authors
- Vecht, C. J., Haaxma-Reiche, H., J. van Putten, W. L., Visser, M. D., Vries, E. P., & Twijnstra, A.
- Venue
- Neurology
- Published
- 1989-09
- Volume
- 39
- Issue
- 9
- Pages
- 1255-1255
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2029139723
- Cited by
- 266
- References
- 0
- FWCI
- 4.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Initial bolus of conventional versus high‐dose dexamethasone in metastatic spinal cord compression. https://app.cochat.ai/papers/10.1212/wnl.39.9.1255
- The paper
- Vecht, C. J., Haaxma-Reiche, H., J. van Putten, W. L., Visser, M. D., Vries, E. P., & Twijnstra, A. (1989). Initial bolus of conventional versus high‐dose dexamethasone in metastatic spinal cord compression. Neurology. https://doi.org/10.1212/wnl.39.9.1255
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.