The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Systematic Review of the Diagnosis and Management of Malignant Extradural Spinal Cord Compression: The Cancer Care Ontario Practice Guidelines Initiative‘s Neuro-Oncology Disease Site Group
Abstract
Purpose: This systematic review describes the diagnosis and management of adult patients with a suspected or confirmed diagnosis of extradural malignant spinal cord compression (MSCC). Methods: MEDLINE, CANCERLIT, and the Cochrane Library databases were searched to January 2004 using the following terms: spinal cord compression, nerve compression syndromes, spinal cord neoplasms, clinical trial, meta-analysis, and systematic review. Results: Symptoms for MSCC include sensory changes, autonomic dysfunction, and back pain; however, back pain was not predictive of MSCC. The sensitivity and specificity for magnetic resonance imaging (MRI) range from 0.44 to 0.93 and 0.90 to 0.98, respectively, in the diagnosis of MSCC. The sensitivity and specificity for myelography range from 0.71 to 0.97 and 0.88 to 1.00, respectively. A randomized study detected higher ambulation rates in patients with MSCC who received high-dose dexamethasone before radiotherapy (RT) compared with patients who did not receive corticosteroids before RT (81% v 63% at 3 months, respectively; P = .046). There is no direct evidence that supports or refutes the type of surgery patients should have for the treatment of MSCC, whether surgical salvage should be attempted if patient is progressing on or shortly after RT, and whether patients with spinal instability should be treated with surgery. Conclusion: Patients with symptoms of MSCC should be managed to minimize treatment delay. MRI is the preferred imaging technique. Treatment for patients with MSCC should consider pretreatment ambulatory status, comorbidities, technical surgical factors, the presence of bony compression and spinal instability, potential surgical complications, potential RT reactions, and patient preferences.
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Cites
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Emergency treatment of malignant extradural spinal cord compression: an evidence-based guideline.
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Cited by
Chou, R., Qaseem, A., Snow, V., Casey, D., Cross, J. T., Shekelle, P., Owens, D. K., & for the Clinical Efficacy Assessment Subcommittee of the American College of Physicians and the American College of Physicians/American Pain Society Low Back Pain Guidelines Panel* (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-147-7-200710020-00006 · Cited by 2,718
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Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
Parker, C., Castro, E., Fizazi, K., Heidenreich, A., Ost, P., Procopio, G., Tombal, B., & Gillessen, S. (2020) · Annals of Oncology · doi:10.1016/j.annonc.2020.06.011 · Cited by 977
Wassenaar, M., van Rijn, R. M., van Tulder, M. W., Verhagen, A. P., van der Windt, D. A. W. M., Koes, B. W., de Boer, M. R., Ginai, A. Z., & Ostelo, R. W. J. G. (2012) · European Spine Journal · doi:10.1007/s00586-011-2019-8 · Cited by 161
Hoskin, P. J., Hopkins, K., Misra, V., Holt, T., McMenemin, R., Dubois, D., McKinna, F., Foran, B., Madhavan, K., MacGregor, C., et al. (2019) · JAMA · doi:10.1001/jama.2019.17913 · Cited by 120
Metadata
- Authors
- Loblaw, D. A., Perry, J., Chambers, A., & Laperriere, N. J.
- Venue
- Journal of Clinical Oncology
- Published
- 2005-03-20
- Volume
- 23
- Issue
- 9
- Pages
- 2028-2037
- ISSN
- 0732-183X (ISSN-L)
- 1527-7755
- OpenAlex
- W4236195741
- Cited by
- 325
- References
- 10
- FWCI
- 2.10
- Type
- journal article
- Language
- en
- Open access
- closed
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