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Environmental risk factors in Parkinson's disease

Koller, W., Vetere-Overfield, B., Gray, C., Alexander, C., Chin, T., Dolezal, J., Hassanein, R., Tanner, C.·1990·Neurology

Abstract

To investigate possible risk factors for Parkinson's disease (PD) we conducted a case-control study of 150 PD patients and 150 age- and sex-matched controls. We interviewed and examined all 300 subjects. We collected demographic data including lifetime histories of places of residence, source of drinking water, and occupations such as farming. Subjects completed a detailed questionnaire regarding herbicide/pesticide exposure. Rural living and drinking well water were significantly increased in the PD patients. This was observed regardless of age at disease onset. Drinking well water was dependent on rural living. There were no significant differences between cases and controls for farming or any measure of exposure to herbicides or pesticides. These data provide further evidence that an environmental toxin could be involved in the etiology of PD.

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Metadata

Authors
Koller, W., Vetere-Overfield, B., Gray, C., Alexander, C., Chin, T., Dolezal, J., Hassanein, R., & Tanner, C.
Venue
Neurology
Published
1990-08
Volume
40
Issue
8
Pages
1218-1218
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2034067256
Cited by
260
References
0
FWCI
7.80
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Environmental risk factors in Parkinson's disease. https://app.cochat.ai/papers/10.1212/wnl.40.8.1218
The paper
Koller, W., Vetere-Overfield, B., Gray, C., Alexander, C., Chin, T., Dolezal, J., Hassanein, R., & Tanner, C. (1990). Environmental risk factors in Parkinson's disease. Neurology. https://doi.org/10.1212/wnl.40.8.1218

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.