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Cited by 225

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Cytokine mRNA levels in mononuclear blood cells from patients with multiple sclerosis

Rieckmann, P., Albrecht, M., Kitze, B., Weber, T., Tumani, H., Broocks, A., Lüer, W., Poser, S.·1994·Neurology

Abstract

We determined the cytokine messenger RNA (mRNA) expression pattern of blood mononuclear cells in 45 patients with the relapsing-remitting form of MS and 32 patients with other neurologic diseases. Using a semiquantitative polymerase chain reaction method, we detected significantly higher levels of tumor necrosis factor-alpha and lymphotoxin mRNA in patients with relapsing compared to those with stable disease (p < 0.001), but transforming growth factor-beta and interleukin-10 mRNA expressions were higher in patients with stable disease.

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Metadata

Authors
Rieckmann, P., Albrecht, M., Kitze, B., Weber, T., Tumani, H., Broocks, A., Lüer, W., & Poser, S.
Venue
Neurology
Published
1994-08
Volume
44
Issue
8
Pages
1523-1523
ISSN
  • 0028-3878 (ISSN-L)
  • 1526-632X
OpenAlex
W2007703142
Cited by
225
References
0
FWCI
12.16
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Cytokine mRNA levels in mononuclear blood cells from patients with multiple sclerosis. https://app.cochat.ai/papers/10.1212/wnl.44.8.1523
The paper
Rieckmann, P., Albrecht, M., Kitze, B., Weber, T., Tumani, H., Broocks, A., Lüer, W., & Poser, S. (1994). Cytokine mRNA levels in mononuclear blood cells from patients with multiple sclerosis. Neurology. https://doi.org/10.1212/wnl.44.8.1523

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.