Micturitional disturbance in pure autonomic failure
Abstract
We obtained micturitional histories and performed urodynamic studies in six patients with pure autonomic failure. All patients had urinary symptoms. Urodynamic studies showed postmicturition residuals in two, small bladder capacities in two, detrusor hyperreflexia in four, low bladder compliance in two, detrusor-external sphincter dyssynergia in one, neurogenic sphincter electromyography in three, and denervation supersensitivity of the bladder in two. Micturitional disturbance is a common feature in pure autonomic failure because of peripheral and central types of abnormalities.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Pure autonomic failure is a chronic neurogenic autonomic disorder in which gastrointestinal involvement may include constipation and other manifestations of dysmotility.
“Pure autonomic failure (PAF) is a chronic neurogenic autonomic disorder in which gastrointestinal involvement may include constipation and other manifestations of dysmotility (Sakakibara et al., 2000; Thatcher et al., 1987; Yamanaka et al., 2006).”
From Autonomic nervous system and gastrointestinal manifestations with an emphasis on gastric dysfunction (2026) · cites this paper as Sakakibara et al., 2000
Cites
The Consensus Committee of the American Autonomic Society and the American Academy of Neurology (1996) · Neurology · doi:10.1212/wnl.46.5.1470 · Cited by 1,238 · see citing works
A PET study on brain control of micturition in humans
Blok, B. F. M. (1997) · Brain · doi:10.1093/brain/120.1.111 · Cited by 507 · see citing works
Hague, K., Lento, P., Morgello, S., Caro, S., & Kaufmann, H. (1997) · Acta Neuropathologica · doi:10.1007/s004010050693 · Cited by 209 · see citing works
AUTONOMIC FAILURE WITH ORTHOSTATIC HYPOTENSION DUE TO INTERMEDIOLATERAL COLUMN DEGENERATION
JOHNSON, R. H., Lee, G. D. J., Oppenheimer, D. R., & Spalding, J. M. K. (1966) · QJM · doi:10.1093/oxfordjournals.qjmed.a067077 · Cited by 126 · see citing works
Voiding and MRI Analysis of the Brain
Sakakibara, R., Fowler, C. J., & Hattori, T. (1999) · International Urogynecology Journal · doi:10.1007/s001920050044 · Cited by 53 · see citing works
Self-citationMicturitional Disturbance in Multiple System Atrophy
Sakakibara, R., Hattori, T., Tojo, M., Yamanishi, T., Yasuda, K., & Hirayama, K. (1993) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.1993.tb01804.x · Cited by 32 · see citing works
Self-citationPure Progressive Autonomic Failure: A Clinicopathological Study
Terao, Y., Takeda, K., Sakuta, M., Nemoto, T., Takemura, T., & Kawai, M. (2008) · European Neurology · doi:10.1159/000116985 · Cited by 21 · see citing works
(1995) · Elsevier eBooks · doi:10.1016/b978-0-7506-1183-1.50017-6 · Cited by 8 · see citing works
Multisystem evaluation in one case of pure autonomic failure.
Santangelo, L., Mandarino, G., Biase, L. D., Pesce, F., & Giacomini, P. (1991) · PubMed · Cited by 3 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Gastrointestinal motility disorders in neurologic disease
Camilleri, M. (2021) · Journal of Clinical Investigation · doi:10.1172/jci143771 · Cited by 211 · see citing works
MIBG myocardial scintigraphy in pre-motor Parkinson's disease: A review
Sakakibara, R., Tateno, F., Kishi, M., Tsuyusaki, Y., Terada, H., & Inaoka, T. (2013) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2013.11.001 · Cited by 108 · see citing works
Self-citationProgression and prognosis in pure autonomic failure (PAF): comparison with multiple system atrophy
Mabuchi, N. (2005) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2004.049023 · Cited by 69 · see citing works
Pupil Abnormalities in Selected Autonomic Neuropathies
Bremner, F., & Smith, S. (2006) · Journal of Neuro-Ophthalmology · doi:10.1097/01.wno.0000235564.50518.1b · Cited by 65 · see citing works
Sakakibara, R., Panicker, J. N., Simeoni, S., Uchiyama, T., Yamamoto, T., Tateno, F., Kishi, M., & Aiba, Y. (2018) · Clinical Autonomic Research · doi:10.1007/s10286-018-0550-y · Cited by 58 · see citing works
Self-citationLower urinary tract function in dementia with Lewy bodies (DLB)
Tateno, F., Sakakibara, R., Ogata, T., Kishi, M., Tsuyusaki, Y., Takahashi, O., Sugiyama, M., & Tateno, A. (2014) · Movement Disorders · doi:10.1002/mds.25985 · Cited by 56 · see citing works
Self-citationNeurogenic lower urinary tract dysfunction: evaluation and management
Tudor, K. I., Sakakibara, R., & Panicker, J. N. (2016) · Journal of Neurology · doi:10.1007/s00415-016-8212-2 · Cited by 56 · see citing works
Self-citationSphincter EMG as a diagnostic tool in autonomic disorders
Sakakibara, R., Uchiyama, T., Yamanishi, T., & Kishi, M. (2008) · Clinical Autonomic Research · doi:10.1007/s10286-008-0489-5 · Cited by 55 · see citing works
Self-citationRemission of chronic inflammatory demyelinating polyneuropathy after alemtuzumab (Campath 1H)
Hirst, C. L. (2006) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2005.076869 · Cited by 54 · see citing works
Lower urinary tract function in dementia of Lewy body type
Sakakibara, R. (2005) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2004.046243 · Cited by 53 · see citing works
Self-citationPanicker, J. N., Simeoni, S., Miki, Y., Batla, A., Iodice, V., Holton, J. L., Sakakibara, R., & Warner, T. T. (2019) · Journal of Neurology · doi:10.1007/s00415-019-09597-2 · Cited by 45 · see citing works
Self-citationPrimary Sjogren's syndrome presenting with generalized autonomic failure
Sakakibara, R., Hirano, S., Asahina, M., Sawai, S., Nemoto, Y., Hiraga, A., Uchiyama, T., & Hattori, T. (2004) · European Journal of Neurology · doi:10.1111/j.1468-1331.2004.00846.x · Cited by 37 · see citing works
Self-citationChelban, V., Catereniuc, D., Daniela, A., Gasnaș, D., Vichayanrat, E., Iodice, V., Groppa, S. A., & Houlden, H. (2020) · Journal of Neurology · doi:10.1007/s00415-020-09881-6 · Cited by 35 · see citing works
Autonomic dysfunction in genetic forms of synucleinopathies
Chelban, V., Vichayanrat, E., Schottlaende, L., Iodice, V., & Houlden, H. (2018) · Movement Disorders · doi:10.1002/mds.27343 · Cited by 28 · see citing works
Yamamoto, T., Sakakibara, R., Yamanaka, Y., Uchiyama, T., Asahina, M., Liu, Z., Ito, T. K., Koyama, Y., Awa, Y., Yamamoto, K., et al. (2006) · Clinical Autonomic Research · doi:10.1007/s10286-006-0358-z · Cited by 24 · see citing works
Self-citationChronic intestinal pseudo-obstruction as the initial feature of pure autonomic failure
Yamanaka, Y. (2006) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2005.079905 · Cited by 19 · see citing works
Thaisetthawatkul, P. (2016) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-016-0673-2 · Cited by 18 · see citing works
Autonomic dysfunction in cystic fibrosis.
Mirakhur, A., & Walshaw, M. J. (2003) · Europe PMC (PubMed Central) · Cited by 16 · see citing works
Lower urinary tract dysfunction reported in autonomic disorders
Vichayanrat, E., Koay, S., Hentzen, C., Wright, S. L., Batla, A., Simeoni, S., Iodice, V., & Panicker, J. N. (2025) · Autonomic Neuroscience · doi:10.1016/j.autneu.2025.103341 · Cited by 7 · see citing works
Pure autonomic failure and the differential diagnosis of autonomic peripheral neuropathies
González‐Duarte, A., Varma-Doyle, A. V., & Freeman, R. L. (2021) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000985 · Cited by 7 · see citing works
Pelvic autonomic dysfunction is common in patients with pure autonomic failure
Vichayanrat, E., Hentzen, C., Simeoni, S., Pakzad, M. H., Iodice, V., & Panicker, J. N. (2024) · European Journal of Neurology · doi:10.1111/ene.16486 · Cited by 5 · see citing works
Kim, Y.-J., Lee, C., Kim, S., Jang, J., Lee, S., & Lee, S.-H. (2019) · Journal of Neurology · doi:10.1007/s00415-019-09617-1 · Cited by 5 · see citing works
Panicker, J. N., & Manji, H. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511762611.020 · Cited by 4 · see citing works
Haddad, R., Panicker, J. N., Verbakel, I., Dhondt, K., Ghijselings, L., Hervé, F., Petrović, M., Whishaw, M., Bliwise, D. L., & Everaert, K. (2023) · The French Journal of Urology · doi:10.1016/j.purol.2023.01.002 · Cited by 3 · see citing works
Lower urinary tract dysfunction in patients with dysautonomia
Aubin, M. S., Shridharani, A., Barboi, A. C., Guralnick, M. L., Jaradeh, S. S., Prieto, T. E., & O’Connor, R. C. (2015) · Clinical Autonomic Research · doi:10.1007/s10286-015-0320-z · Cited by 2 · see citing works
Averbeck, M. A., Cito, G., Drake, M. J., Khastgir, J., Silva, R. P. E., Fulford, S., & Reid, S. (2019) · Springer eBooks · doi:10.1007/978-3-030-27747-5_8 · Cited by 2 · see citing works
Fowler, C. J., Panicker, J. N., & Emmanuel, A. V. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511762611.013 · Cited by 2 · see citing works
Crosstalk between bladder-cardiovascular autonomic nervous system in synucleinopathies
Sakakibara, R., Uchiyama, T., & Yamamoto, T. (2025) · Autonomic Neuroscience · doi:10.1016/j.autneu.2025.103320 · Cited by 1 · see citing works
Self-citationSphincter EMG for Diagnosing Multiple System Atrophy and Related Disorders
Sakakibara, R., Uchiyama, T., Yamamoto, T., Tateno, F., Yamanishi, T., Kishi, M., & Tsuyusaki, Y. (2012) · InTech eBooks · doi:10.5772/45880 · Cited by 1 · see citing works
Self-citationPanicker, J. N., Fowler, C. J., & Dasgupta, R. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4377-0434-1.00048-7 · Cited by 1 · see citing works
Not all dysautonomias are created equal
Palma, J. (2015) · Clinical Autonomic Research · doi:10.1007/s10286-015-0329-3 · Cited by 1 · see citing works
Autonomic nervous system and gastrointestinal manifestations with an emphasis on gastric dysfunction
Shouman, K., Camilleri, M., & Singer, W. (2026) · Autonomic Neuroscience · doi:10.1016/j.autneu.2026.103474
Khurana, R. K. (2021) · Springer eBooks · doi:10.1007/978-3-030-62263-3_24
Drake, M. J., Nettleton, J., & Belal, M. (2021) · doi:10.1002/9781119245957.ch16
246 NOCTURNAL POLYURIA IS COMMON IN PATIENTS WITH PURE AUTONOMIC FAILURE
Vichayanrat, E., Hentzen, C., Simeoni, S., Pakzad, M. H., Iodice, V., & Panicker, J. N. (2022) · Continence · doi:10.1016/j.cont.2022.100335
Bhattacharjee, S., & Alsukhni, R. A. (2022) · Annals of Indian Academy of Neurology · doi:10.4103/aian.aian_1078_21
Yasmin, H., Aleksejeva, K., Johnston, L., Malladi, P., Simeoni, S., & Pakzad, M. H. (2026) · Autonomic Neuroscience · doi:10.1016/j.autneu.2026.103452
- Authors
- Sakakibara, R., Hattori, T., Uchiyama, T., Asahina, M., & Yamanishi, T.
- Affiliations
- Chiba University (JP)
- Venue
- Neurology
- Published
- 2000-01-25
- Volume
- 54
- Issue
- 2
- Pages
- 499-499
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2036494706
- Cited by
- 38
- References
- 9
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 1 · 2019: 3 · 2018: 2 · 2016: 2 · 2015: 2 · 2014: 2 · 2013: 1 · 2012: 2
- FWCI
- 0.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neurology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Rheumatology › Pelvic floor disorders treatments
- Keywords
- pure autonomic failure, micturition disorders, urinary symptoms, neurogenic detrusor overactivity, bladder compliance, detrusor-external sphincter dyssynergia, neurogenic bladder, denervation supersensitivity, urodynamic abnormalities
- MeSH terms
- Aged, Autonomic Nervous System Diseases, Urinary Bladder, Urinary Bladder Diseases, Electromyography, Female, Humans, Male, Middle Aged, Reflex, Abnormal, Urinary Incontinence, Urodynamics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review