The DOI matches its Crossref record; 147 of the 147 references it cites were found in a registry or an index.
Practice parameter: Management of dementia (an evidence-based review)
Abstract
To the Editor: In the recently published “Practice parameter: Management of dementia (an evidence-based review),”1 the evidence for vitamin E was given significantly greater credibility than the comparable, if not greater, evidence for ginkgo biloba extract (GBE). The reviewers considered vitamin E a guideline but the single controlled trial2 was much less conclusive than the practice parameter suggests. The uncorrected, first-pass data analysis revealed no significant ( p < 0.05) beneficial effect of vitamin E. After correction for a slight baseline difference among the four groups in the Mini-Mental State Examination (MMSE) score ( p = 0.1), the selegeline, vitamin E, and combined groups had slightly better outcomes as defined by death, nursing home placement, conversion to Clinical Dementia Rating score three, or decrease in activities of daily living. Concerns about the analysis have already been raised.3 Additionally, there were no significant effects on cognitive measures in the study, certainly raising the possibility that any poorly defined effect of vitamin E on the outcome measure may have nothing specifically to do with AD. Whereas the combined outcome measure has public health implications, it is affected by types of behaviors and clinical events other than severity of AD that contribute to nursing home placement and death; e.g., aggressive behaviors, incontinence, and vascular disease. It could be argued that all these factors should have been covariates in the analysis. Another formal …
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A Controlled Trial of Selegiline, Alpha-Tocopherol, or Both as Treatment for Alzheimer's Disease
Sano, M., Ernesto, C., Thomas, R. G., Klauber, M. R., Schafer, K., Grundman, M., Woodbury, P., Growdon, J., Cotman, C. W., Pfeiffer, E., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199704243361704 · Cited by 2,380
Doody, R. S., Stevens, J. C., Beck, C., Dubinsky, R. M., Kaye, J. A., Gwyther, L., Mohs, R. C., Thal, L. J., Whitehouse, P. J., DeKosky, S. T., et al. (2001) · Neurology · doi:10.1212/wnl.56.9.1154 · Cited by 1,720
A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
Rogers, S. L., Farlow, M. R., Doody, R. S., Mohs, R., Friedhoff, L. T., & Donepezil Study Group* (1998) · Neurology · doi:10.1212/wnl.50.1.136 · Cited by 1,618
Knapp, M. J. (1994) · JAMA · doi:10.1001/jama.271.13.985 · Cited by 1,004
Clinical trial of indomethacin in Alzheimer's disease
Rogers, J., Kirby, L. C., Hempelman, S. R., Berry, D. L., McGeer, P. L., Kaszniak, A. W., Zalinski, J., Cofield, M., Mansukhani, L., Willson, P., et al. (1993) · Neurology · doi:10.1212/wnl.43.8.1609 · Cited by 999
Mulnard, R. A., Cotman, C. W., Kawas, C., van Dyck, C. H., Sano, M., Doody, R., Koss, E., Pfeiffer, E., Jin, S., Gamst, A., et al. (2000) · JAMA · doi:10.1001/jama.283.8.1007 · Cited by 991
A Placebo-Controlled, Double-blind, Randomized Trial of an Extract of Ginkgo Biloba for Dementia
Le Bars, P. L. (1997) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1997.03550160047037 · Cited by 966
Rosler, M., Anand, R., Cicin-Sain, A., Gauthier, S., Agid, Y., Dal-Bianco, P., Stahelin, H. B., Hartman, R., Gharabawi, M., & Bayer, T. (1999) · BMJ · doi:10.1136/bmj.318.7184.633 · Cited by 943
A 5-month, randomized, placebo-controlled trial of galantamine in AD
Tariot, P. N., Solomon, P. R., Morris, J. C., Kershaw, P., Lilienfeld, S., Ding, C., & the Galantamine USA- Study Group (2000) · Neurology · doi:10.1212/wnl.54.12.2269 · Cited by 921
Raskind (2000) · doi:10.1212/wnl.54.12.2261 · Cited by 870
Cited by
Meta-Analysis: High-Dosage Vitamin E Supplementation May Increase All-Cause Mortality
Miller, E. R., Pastor-Barriuso, R., Dalal, D., Riemersma, R. A., Appel, L. J., & Guallar, E. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-1-200501040-00110 · Cited by 2,577
NELSON, M. E., REJESKI, W. J., BLAIR, S. N., DUNCAN, P. W., JUDGE, J. O., KING, A. C., MACERA, C. A., & CASTANEDA-SCEPPA, C. (2007) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3180616aa2 · Cited by 2,089
Nonpharmacological therapies in Alzheimer’s disease: a systematic review of efficacy
Olazarán, J., Reisberg, B., Clare, L., Cruz, I., Peña-Casanova, J., del Ser, T., Woods, B., Beck, C., Auer, S., Lai, C., et al. (2010) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000316119 · Cited by 937
Mapping Scores Onto Stages: Mini-Mental State Examination and Clinical Dementia Rating
Perneczky, R., Wagenpfeil, S., Komossa, K., Grimmer, T., Diehl, J., & Kurz, A. (2006) · The American Journal of Geriatric Psychiatry · doi:10.1097/01.jgp.0000192478.82189.a8 · Cited by 768
Treatment of Alzheimer's disease; current status and new perspectives
scarpini, E., Schelterns, P., & Feldman, H. (2003) · The Lancet Neurology · doi:10.1016/s1474-4422(03)00502-7 · Cited by 721
Metadata
- Authors
- Oken, B. S.
- Venue
- Neurology
- Published
- 2001-12-26
- Volume
- 57
- Issue
- 12
- Pages
- 2323-2323
- ISSN
- 0028-3878 (ISSN-L)
- 1526-632X
- OpenAlex
- W2065254178
- Cited by
- 351
- References
- 147
- FWCI
- 17.02
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
