Cited by 172Statistical Methods in Clinical TrialsStatistical Methods and InferenceStatistical Methods and Bayesian Inference

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E-values: Calibration, combination and applications

Open access
Vovk, Vladimir, Wang, Ruodu·2021·The Annals of Statistics

Abstract

Multiple testing of a single hypothesis and testing multiple hypotheses are usually done in terms of p-values. In this paper, we replace p-values with their natural competitor, e-values, which are closely related to betting, Bayes factors and likelihood ratios. We demonstrate that e-values are often mathematically more tractable; in particular, in multiple testing of a single hypothesis, e-values can be merged simply by averaging them. This allows us to develop efficient procedures using e-values for testing multiple hypotheses.

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  • The paper's sequential tools are conformal test martingales.

    “our sequential tools are conformal test martingales (Vovk, 2021)”

    From The Limits of Query Monitoring against Distributed Model Extraction (2026) · cites this paper as Vovk, 2021

    The “Testing with martingales” section explains how sequential e-values yield test supermartingales and, under an equality condition, test martingales. Our copy does not identify these as conformal test martingales, so it supports the martingale connection but not the conformal qualification. No page number is available in the indexed passages. (LLM, conf=0.82)

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Research works printed but not linked: 21

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  9. Fisher, R. A. (1932). Statistical Methods for Research Workers, 4th ed. Oliver and Boyd, Edinburgh. Section 21.1 on combining independent p-values first appears in this edition and is present in all subsequent editions.
  10. Grünwald, P., de Heide, R. and Koolen, W. M. (2020). Safe testing. Technical report. Available at arXiv:1906.07801 [math.ST]. · arXiv
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  15. Shafer, G. (2019). The language of betting as a strategy for statistical and scientific communication. Technical report. Available at arXiv:1903.06991 [math.ST]. J. R. Stat. Soc., A. To appear. · arXiv
  16. Shafer, G. and Vovk, V. (2019). Game-Theoretic Foundations for Probability and Finance. Wiley, Hoboken, NJ. · DOI
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  18. Vovk, V. and Wang, R. (2020). Combining p-values via averaging. Technical report. Available at arXiv:1212.4966 [math.ST]. Biometrika. To appear. https://doi.org/10.1093/biomet/asaa027. · DOI
  19. Vovk, V. and Wang, R. (2021). Supplement to “E-values: Calibration, combination, and applications.” https://doi.org/10.1214/20-AOS2020SUPP · DOI
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Metadata

Authors
Vovk, V., & Wang, R.
Affiliations
  • University of London (GB)
  • University of Waterloo (CA)
Venue
The Annals of Statistics
Published
2021-06-01
Volume
49
Issue
3
Pages
1736-1754
ISSN
  • 0090-5364 (ISSN-L)
  • 2168-8966
OpenAlex
W3087003407
Cited by
172
References
1
Citations by year
2026: 44 · 2025: 35 · 2024: 27 · 2023: 28 · 2022: 19 · 2021: 14
FWCI
15.95
Type
journal article
Language
en
Open access
Locations
  • The Annals of Statistics (publishedVersion)
  • arXiv (Cornell University) (submittedVersion)
  • arXiv (Cornell University)
Funders
Natural Sciences and Engineering Research Council of Canada (rgpin-2018-03823, RGPAS‐2018‐522590, RGPAS-2018, RGPIN 2018)
Topics
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Inference
  • Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods and Bayesian Inference
Keywords
E-value, multiple comparisons, p-values, calibration, betting, Bayes factor, likelihood ratios

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