Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions

Zeng, Xin, Huang, He, Tamai, Keiko, Zhang, Xinjun, Harada, Yuko, Yokota, Chika, Almeida, Karla, Wang, Jianbo +5 more·2008·Development

DOI 10.1242/dev.013540

Cited by (492)

Items 101–200 of 492

Piperine suppresses the Wnt/β-catenin pathway and has anti-cancer effects on colorectal cancer cells
Gracielle C. de Almeida, Luiz Fernando Silva Oliveira, Danilo Predes, Harold Hilarion Fokoue, Ricardo Machado Kuster, Felipe Leite de Oliveira, Fábio A. Mendes, José G. Abreu · 2020 · Scientific Reports
Role of Wnt5a in the Pathogenesis of Inflammatory Diseases
Mehran Pashirzad, Mojtaba Shafiee, Farzad Rahmani, Reihane Behnam‐Rassouli, Fatemeh Hoseinkhani, Mikhail Ryzhikov, Maryam Moradi Binabaj, Mohammad Reza Parizadeh, Amir Avan, Seyed Mahdi Hassanian · 2016 · Journal of Cellular Physiology
Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC
Ranjan Preet, Purusottam Mohapatra, Dipon Das, Shakti Ranjan Satapathy, Tathagata Choudhuri, Michael D. Wyatt, Chanakya Nath Kundu · 2012 · Carcinogenesis
Wnt–β-catenin signaling
Ken M. Cadigan · 2008 · Current Biology
Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay
Melissa V. R. Gammons, Trevor J. Rutherford, Zachary Steinhart, Stéphane Angers, Mariann Bienz · 2016 · Journal of Cell Science
The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility
Maki Takagishi, Atsushi Enomoto, Naoya Asai, Kaori Ushida, Takashi Watanabe, Takahiko Hashimoto, Takuya Kato, Liang Weng, Shinji Matsumoto, Masato Asai et al. · 2012 · Nature Communications
Diverse roles of GSK-3: tumor promoter-tumor suppressor, target in cancer therapy.
J. McCubrey, Nicole M. Davis, S. Abrams, G. Montalto, M. Cervello, J. Bäsecke, M. Libra, F. Nicoletti, L. Cocco, A. Martelli et al. · 2014 · Advances in Biological Regulation
Wnt signaling in hematopoiesis: Crucial factors for self‐renewal, proliferation, and cell fate decisions
Frank J. T. Staal, Tiago Cunha Luis · 2010 · Journal of Cellular Biochemistry
Sodium selenate activated Wnt/β-catenin signaling and repressed amyloid-β formation in a triple transgenic mouse model of Alzheimer's disease
Na Jin, Huazhang Zhu, Xiao Liang, Wei Huang, Qingguo Xie, Peng Xiao, Jiazuan Ni, Qiong Liu · 2017 · Experimental Neurology
Roles of Non-Canonical Wnt Signalling Pathways in Bone Biology
Jasna Lojk, Janja Marc · 2021 · International Journal of Molecular Sciences
Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family
Bin Zhang, José G. Abreu, Kelu Zhou, Ying Chen, Yang Hu, Ti Zhou, Xi He, Jian‐xing Ma · 2010 · Proceedings of the National Academy of Sciences
Methylation by protein arginine methyltransferase 1 increases stability of Axin, a negative regulator of Wnt signaling
Boksik Cha, W. Kim, YoungHa Kim, Byul Nim Hwang, So Yeon Park, Juyong Yoon, W S Park, J. W. Cho, Mark T. Bedford, Eek‐hoon Jho · 2011 · Oncogene
Microglia Polarization, Gene-Environment Interactions and Wnt/β-Catenin Signaling: Emerging Roles of Glia-Neuron and Glia-Stem/Neuroprogenitor Crosstalk for Dopaminergic Neurorestoration in Aged Parkinsonian Brain
Francesca L’Episcopo, Cataldo Tirolo, Maria Francesca Serapide, Salvatore Caniglia, Nunzio Testa, Loredana Leggio, Silvia Vivarelli, Nunzio Iraci, Stefano Pluchino, Bianca Marchetti · 2018 · Frontiers in Aging Neuroscience
The dark sides of capillary morphogenesis gene 2
Julie Deuquet, Ekkehart U. Lausch, Andrea Superti‐Furga, F Gisou van der Goot · 2011 · The EMBO Journal
Coordinated Action of CK1 Isoforms in Canonical Wnt Signaling
Beatriz del Valle‐Pérez, Oriol Arqués, Meritxell Vinyoles, Antonio Garcı́a de Herreros, Mireia Duñach · 2011 · Molecular and Cellular Biology
NLK positively regulates Wnt/β‐catenin signalling by phosphorylating LEF1 in neural progenitor cells
Ota, Satoshi, Ishitani, Shizuka, Shimizu, Nobuyuki, Matsumoto, Kunihiro, Itoh, Motoyuki, Ishitani, Tohru · 2012 · The EMBO Journal
Therapeutic Potential of a Monoclonal Antibody Blocking the Wnt Pathway in Diabetic Retinopathy
Kyungwon Lee, Yang Hu, Lexi Ding, Ying Chen, Yusuke Takahashi, Robert Mott, Jian‐xing Ma · 2012 · Diabetes
Presenilin Deficiency or Lysosomal Inhibition Enhances Wnt Signaling through Relocalization of GSK3 to the Late-Endosomal Compartment
Radek Dobrowolski, Philipp Vick, Diego Ploper, Iwona Gumper, Harriet Snitkin, David D. Sabatini, Edward M. De Robertis · 2012 · Cell Reports
Wnt/β-catenin pathway in bone cancers
Jian Tian, Hongbo He, Guanghua Lei · 2014 · Tumor Biology
Inhibition of Connective Tissue Growth Factor Overexpression in Diabetic Retinopathy by SERPINA3K via Blocking the WNT/β-Catenin Pathway
Bin Zhang, Kelu Zhou, Jian‐xing Ma · 2010 · Diabetes
The Dishevelled Protein Family
Marek Mlodzik · 2016 · Current topics in developmental biology/Current Topics in Developmental Biology
The roles of Wnt/β-catenin signaling pathway related lncRNAs in cancer
Xiao-Yi Hu, Pingfu Hou, Teng-Teng Li, Hao-Yu Quan, Min-Le Li, Tian Lin, Jin-Jin Liu, Jin Bai, Junnian Zheng · 2018 · International Journal of Biological Sciences
Wnt/β‐catenin signaling: Structure, assembly and endocytosis of the signalosome
Gabriele Colozza, Bon‐Kyoung Koo · 2021 · Development Growth & Differentiation
Low Density Lipoprotein (LDL) Receptor-related Protein 6 (LRP6) Regulates Body Fat and Glucose Homeostasis by Modulating Nutrient Sensing Pathways and Mitochondrial Energy Expenditure
Wenzhong Liu, Rajvir Singh, Cheol Soo Choi, Hui‐Young Lee, Ali Reza Keramati, Varman T. Samuel, Richard P. Lifton, Gerald I. Shulman, Arya Mani · 2012 · Journal of Biological Chemistry
Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway
Hua, Yue, Yang, Yilin, Li, Qian, He, Xinyu, Zhu, Wei, Wang, Jiyong, Gan, Xiaoqing · 2018 · Journal of Biological Chemistry
A p120-catenin–CK1ε complex regulates Wnt signaling
David Casagolda, Beatriz del Valle‐Pérez, Gabriela Valls, Ero Lugilde, Meritxell Vinyoles, Juan Casado‐Vela, Guiomar Solanas, Eduard Batlle, Albert B. Reynolds, José Ignacio Casal et al. · 2010 · Journal of Cell Science
PTK7 modulates Wnt signaling activity via LRP6
Naama Bin-Nun, Hava Lichtig, Anastasia Malyarova, Michal Levy, Sarah Elias, Dale Frank · 2013 · Development
Both LRP5 and LRP6 Receptors Are Required to Respond to Physiological Wnt Ligands in Mammary Epithelial Cells and Fibroblasts
Shruti Goel, Emily N. Chin, Saja A. Fakhraldeen, Scott Michael Berry, David J. Beebe, Caroline M. Alexander · 2012 · Journal of Biological Chemistry
mTOR complex 1 controls the nuclear localization and function of glycogen synthase kinase 3β
Stephen James Bautista, Ivan Boras, Adriano Vissa, Noa Mecica, Christopher M. Yip, Peter Kijun Kim, Costin N. Antonescu · 2018 · Journal of Biological Chemistry
Curcumin suppresses proliferation and induces apoptosis of human hepatocellular carcinoma cells via the wnt signaling pathway
Marvin Xuejun Xu, Linlin Zhao, Chaoyang Deng, Lu Yang, Yang Wang, TAO GUO, Lifang Li, Jianping Lin, Lirong Zhang · 2013 · International Journal of Oncology
Vascular Endothelial Growth Factor Receptor-1 Is Synthetic Lethal to Aberrant β-Catenin Activation in Colon Cancer
Snehal U. Naik, Robin S. Dothager, Jayne C. Marasa, Cory L. Lewis, David R Piwnica-Worms · 2009 · Clinical Cancer Research
MiR-126 promotes coxsackievirus replication by mediating cross-talk of ERK1/2 and Wnt/β-catenin signal pathways
Xin Ye, Maged Gomaa Hemida, Ye Qiu, Paul Hanson, Huifang Mary Zhang, Decheng Yang · 2013 · Cellular and Molecular Life Sciences
WNT10A missense mutation associated with a complete Odonto-Onycho-Dermal Dysplasia syndrome
Sadia Nawaz, Joakim Klar, Muhammad Wajid, Muhammad Qasim Aslam, Muhammad Tariq, Jens Schuster, Shahid Mahmood Baig, Niklas Dahl · 2009 · European Journal of Human Genetics
Amer1/WTX couples Wnt‐induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation
Kristina Tanneberger, Astrid S. Pfister, Katharina Brauburger, Jean Schneikert, Michel V. Hadjihannas, Vı́tězslav Křı́ž, Gunnar Schulte, Vı́tězslav Bryja, Jürgen Behrens · 2011 · The EMBO Journal
Wnt-Induced Stabilization of KDM4C Is Required for Wnt/β-Catenin Target Gene Expression and Glioblastoma Tumorigenesis
Yaohui Chen, Runping Fang, Chen Yue, Guoqiang Chang, Peng Li, Qing Guo, Jing Wang, Aidong Zhou, Sicong Zhang, Gregory N. Fuller et al. · 2019 · Cancer Research
Dissecting Molecular Differences between Wnt Coreceptors LRP5 and LRP6
Bryan T. MacDonald, Mikhail V. Semënov, He Huang, Xi He · 2011 · PLoS ONE
Updating the Wnt pathways
Jia Yu, D. Virshup · 2014 · Bioscience Reports
Wnt/β-catenin Signaling Inhibitors
Xun Zhang, Nazhen Dong, Xiaoyan Hu · 2023 · Current Topics in Medicinal Chemistry
Dickkopf-1: a suitable target for the management of myeloma bone disease
Maria Gavriatopoulou, Meletios Athanasios Dimopoulos, Dimitrios Christoulas, Magdalini Migkou, Marina Iakovaki, Maria Aslani Gkotzamanidou, Evangelos Terpos · 2009 · Expert Opinion on Therapeutic Targets
Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches
Emenike K. Onyido, Eloise Sweeney, Abdolrahman Shams Nateri · 2016 · Molecular Cancer
The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic?
Vı́tězslav Bryja, Igor Červenka, Lukáš Čajánek · 2017 · Critical Reviews in Biochemistry and Molecular Biology
Wnt pathway activation by ADP-ribosylation
Eungi Yang, Ofelia Tacchelly‐Benites, Zhenghan Wang, Michael P. Randall, Ai Tian, Hassina Benchabane, Sarah J. Freemantle, Claudio W. Pikielny, Nicholas S. Tolwinski, Ethan N. Lee et al. · 2016 · Nature Communications
G Protein-coupled Receptor Kinases Phosphorylate LRP6 in the Wnt Pathway
Minyong Chen, Melanie Philipp, Jiangbo Wang, Richard T. Premont, Tiffany Runyan Garrison, Marc G. Caron, Robert J. Lefkowitz, Wei Chen · 2009 · Journal of Biological Chemistry
β-catenin promotes the type I IFN synthesis and the IFN-dependent signaling response but is suppressed by influenza A virus-induced RIG-I/NF-κB signaling
Andrea Hillesheim, Carolin Nordhoff, Yvonne Boergeling, Stephan Ludwig, Viktor Wixler · 2014 · Cell Communication and Signaling
Spatio-temporal Model of Endogenous ROS and Raft-Dependent WNT/Beta-Catenin Signaling Driving Cell Fate Commitment in Human Neural Progenitor Cells
Haack, Fiete, Lemcke, Heiko, Ewald, Roland, Rharass, Tareck, Uhrmacher, Adelinde M. · 2015 · PLOS Computational Biology
Wnt/β-Catenin Pathway Is Regulated by PITX2 Homeodomain Protein and Thus Contributes to the Proliferation of Human Ovarian Adenocarcinoma Cell, SKOV-3
Moitri Basu, Sib Sankar Roy · 2012 · Journal of Biological Chemistry
Daam2 Is Required for Dorsal Patterning via Modulation of Canonical Wnt Signaling in the Developing Spinal Cord
Hyun Kyoung Lee, Benjamin Deneen · 2012 · Developmental Cell
Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members
Ji Yeon Hong, Jae‐Il Park, Kyucheol Cho, Dongmin Gu, Hong Long Ji, Steven E. Artandi, Pierre D. McCrea · 2010 · Journal of Cell Science
The Wnt/β-catenin pathway in human fibrotic-like diseases and its eligibility as a therapeutic target
Maria Vittoria Enzo, Marco Rastrelli, Carlo Riccardo Rossi, Uroš Hladnik, Daniela Segat · 2015 · Molecular and Cellular Therapies
Wnt Signaling in Mammary Glands: Plastic Cell Fates and Combinatorial Signaling
Caroline M. Alexander, S. Goel, Saja A. Fakhraldeen, Sanguk Kim · 2012 · Cold Spring Harbor Perspectives in Biology
The dark sides of amyloid in Alzheimer's disease pathogenesis
Pierpaolo Sorrentino, Antonietta Iuliano, Arianna Polverino, Francesca Jacini, Giuseppe Sorrentino · 2014 · FEBS Letters
Structural and Functional Characterization of the Wnt Inhibitor APC Membrane Recruitment 1 (Amer1)
Tanneberger, Kristina, Pfister, Astrid S., Kriz, Vitezslav, Bryja, Vitezslav, Schambony, Alexandra, Behrens, Jürgen · 2011 · Journal of Biological Chemistry
Caprin-2 enhances canonical Wnt signaling through regulating LRP5/6 phosphorylation
Yu‐Qiang Ding, Ying Xi, Ting Chen, Jiyong Wang, Dong-lei Tao, Zhili Wu, Yiping Li, Chen Li, Rong Zeng, Li Lin · 2008 · The Journal of Cell Biology
Negative feedback regulation of the Wnt pathway by conductin/axin2 involves insensitivity to upstream signalling
Dominic B. Bernkopf, Michel V. Hadjihannas, Jürgen Behrens · 2014 · Journal of Cell Science
Lysophosphatidic Acid Initiates Epithelial to Mesenchymal Transition and Induces β-Catenin-mediated Transcription in Epithelial Ovarian Carcinoma
Rebecca J. Burkhalter, Suzanne D. Westfall, Yueying Liu, Mary Sharon Stack · 2015 · Journal of Biological Chemistry
Normal morphogenesis of epithelial tissues and progression of epithelial tumors
Chun‐Chao Wang, Leen Jamal, Kevin A. Janes · 2011 · WIREs Systems Biology and Medicine
The RNA-binding protein RBM47 inhibits non-small cell lung carcinoma metastasis through modulation of AXIN1 mRNA stability and Wnt/β-catentin signaling
Di-jian Shen, You-hua Jiang, Jian-qiang Li, Liwei Xu, Kai-yi Tao · 2020 · Surgical Oncology
Tissue-specific roles of Axin2 in the inhibition and activation of Wnt signaling in the mouse embryo
Lihui Qian, James P. Mahaffey, Heather L. Alcorn, Kathryn V. Anderson · 2011 · Proceedings of the National Academy of Sciences
14‐3‐3 and β‐catenin are secreted on extracellular vesicles to activate the oncogenic Wnt pathway
Shiri Dovrat, M. Caspi, A. Zilberberg, Lital Lahav, Anastasia Firsow, H. Gur, R. Rosin-Arbesfeld · 2014 · Molecular Oncology
The Role of Fluoxetine in Activating Wnt/β-Catenin Signaling and Repressing β-Amyloid Production in an Alzheimer Mouse Model
Min Huang, Yubin Liang, Hongda Chen, Binchu Xu, Cuicui Chai, Pengfei Xing · 2018 · Frontiers in Aging Neuroscience
Regulation of Osteoblast Metabolism by Wnt Signaling
Megan C. Moorer, Ryan C. Riddle · 2018 · Endocrinology and Metabolism
Keeping Wnt Signalosome in Check by Vesicular Traffic
Qiang Feng, Nan Gao · 2014 · Journal of Cellular Physiology
Colon cancer stem cells – From basic to clinical application
Galina I. Botchkina · 2012 · Cancer Letters
Wnt signaling: the good and the bad
Xi Chen, Jun Yang, Paul M. Evans, Chunming Liu · 2008 · Acta Biochimica et Biophysica Sinica
Gβγ Activates GSK3 to Promote LRP6-Mediated β-Catenin Transcriptional Activity
Kristin K. Jernigan, Christopher S. Cselenyi, Curtis A. Thorne, Alison J. Hanson, Emilios Tahinci, Nicole Hajicek, William M. Oldham, Laura Anne Lee, Heidi E. Hamm, John R. Hepler et al. · 2010 · Science Signaling
Targeting the Wnt Pathway in Cancer: A Review of Novel Therapeutics
Roya Tabatabai, Yuliya P. L. Linhares, David Bolos, Monica M Mita, Alain C. Mita · 2017 · Targeted Oncology
Dickkopfs and Wnt/β-catenin signalling in liver cancer
Sarwat Fatima · 2011 · World Journal of Clinical Oncology
Molecular pathways and therapeutic targets linked to triple-negative breast cancer (TNBC)
Mohd Mustafa, Kashif Abbas, Mudassir Alam, Waleem Ahmad, Moinuddin Moinuddin, Nazura Usmani, Shahid Ali Siddiqui, Safia Habib · 2023 · Molecular and Cellular Biochemistry
Selenium in the Redox Regulation of the Nrf2 and the Wnt Pathway
Regina Brigelius‐Flohé, Anna Patricia Kipp · 2013 · Methods in enzymology on CD-ROM/Methods in enzymology
Canonical Wnt/β-Catenin Signalling Is Essential for Optic Cup Formation
Anna‐Carin Hägglund, Anna Berghard, Leif Carlsson · 2013 · PLoS ONE
Wnt to build a tube: Contributions of Wnt signaling to epithelial tubulogenesis
Rachel K. Miller, Pierre D. McCrea · 2009 · Developmental Dynamics
Dvl2 Promotes Intestinal Length and Neoplasia in the Apc Min Mouse Model for Colorectal Cancer
Ciara Metcalfe, Ashraf E.K. Ibrahim, Michael Graeb, Marc de la Roche, Thomas Schwarz, Marc Fiedler, Douglas J. Winton, Anthony P. Corfield, Mariann Bienz · 2010 · Cancer Research
Differential requirements for β-catenin during mouse development
Stefan Rudloff, Rolf Kemler · 2012 · Development
Helicobacter pylori-induced activation of β-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled
Thorsten Gnad, Maria Feoktistova, Martin Leverkus, Uwe Lendeckel, Michael Naumann · 2010 · Molecular Cancer
CK1 in Developmental Signaling
Jin Jiang · 2016 · Current topics in developmental biology/Current Topics in Developmental Biology
EPH receptor A2 governs a feedback loop that activates Wnt/β-catenin signaling in gastric cancer
Peng Qiu, Ling Chen, Wei Wu, Jia Wang, Xiang Zheng, Zihua Chen, Qin Jiang, Jiaqi Han, Lingyu Wei, Lujuan Wang et al. · 2018 · Cell Death and Disease
Cyclin G2 suppresses Wnt/β-catenin signaling and inhibits gastric cancer cell growth and migration through Dapper1
Jinlan Gao, Chenyang Zhao, Qi Liu, Xiaoyu Hou, Sen Li, Xuesha Xing, Chunhua Yang, Yang Luo · 2018 · Journal of Experimental & Clinical Cancer Research
Regulation of the Low-Density Lipoprotein Receptor-Related Protein LRP6 and Its Association With Disease: Wnt/β-Catenin Signaling and Beyond
Wonyoung Jeong, Eek‐hoon Jho · 2021 · Frontiers in Cell and Developmental Biology
Modulation of post-translational modifications in β-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer
Bharti Garg, Bhuwan Giri, Kaustav Majumder, Vikas Dudeja, Sulagna Banerjee, Ashok Kumar Saluja · 2016 · Cancer Letters
Development of Small Molecules Targeting the Wnt Signaling Pathway in Cancer Stem Cells for the Treatment of Colorectal Cancer
Lele Song, Yuemin Li, Baoming He, Yuan Gong · 2015 · Clinical Colorectal Cancer
Fluorinated N,N-Dialkylaminostilbenes for Wnt Pathway Inhibition and Colon Cancer Repression
Wen Zhang, Vitaliy M. Sviripa, Liliia M. Kril, Xi Chen, Tianxin Yu, Jiandang Shi, Piotr G. Rychahou, Bernard Mark Evers, David S. Watt, Chunming Liu · 2011 · Journal of Medicinal Chemistry
Rough surface topography enhances the activation of Wnt/β‐catenin signaling in mesenchymal cells
Carlo Galli, Giovanni Passeri, Francesca Ravanetti, Erida Elezi, Mario Pedrazzoni, Guido Maria Macaluso · 2010 · Journal of Biomedical Materials Research Part A
PFTK1 interacts with cyclin Y to activate non-canonical Wnt signaling in hepatocellular carcinoma
Tingting Sun, Ngai Na Co, Nathalie Wong · 2014 · Biochemical and Biophysical Research Communications
The N-Terminal Part of the Dishevelled DEP Domain Is Required for Wnt/ β -Catenin Signaling in Mammalian Cells
Petra Paclíková, Ondřej Bernatík, Tomasz Witold Radaszkiewicz, Vı́tězslav Bryja · 2017 · Molecular and Cellular Biology
Pomegranate Bioactive Constituents Suppress Cell Proliferation and Induce Apoptosis in an Experimental Model of Hepatocellular Carcinoma: Role of Wnt/β-Catenin Signaling Pathway
Deepak Bhatia, Roslin J. Thoppil, Animesh Mandal, Karishma Samtani, Altaf S. Darvesh, Anupam Bishayee · 2013 · Evidence-based Complementary and Alternative Medicine
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Tina Hörbelt, Christopher Tacke, Mariya Markova, Daniella Herzfeld de Wiza, Frederique Van de Velde, Marlies Bekaert, Yves Van Nieuwenhove, Silke Hornemann, Maria Rödiger, Nicole Seebeck et al. · 2018 · Diabetologia
Trimeric G protein-dependent signaling by Frizzled receptors in animal development
Diane Egger‐Adam · 2008 · Frontiers in bioscience
Centrosomal localization of Diversin and its relevance to Wnt signaling
Keiji Itoh, Andreas Jenny, Marek Mlodzik, Sergei Y. Sokol · 2009 · Journal of Cell Science
Rare LRP6 Variants Identified in Spina Bifida Patients
Yunping Lei, Kristin Fathe, Danielle McCartney, Huiping Zhu, Wei Yang, Margaret Elizabeth Ross, Gary Michael Shaw, Richard H. Finnell · 2014 · Human Mutation
Carboxypeptidase E: a negative regulator of the canonical Wnt signaling pathway
Nir Skalka, Michal Caspi, E Caspi, Y. Peng Loh, Rina Rosin‐Arbesfeld · 2012 · Oncogene
Transmembrane Protein 198 Promotes LRP6 Phosphorylation and Wnt Signaling Activation
Juan Boo Liang, Yu Fu, Cristina‐Maria Cruciat, Shunji Jia, Ying Wang, Zhen Tong, Qinghua Tao, Dierk Ingelfinger, Michael Boutros, Anming Meng et al. · 2011 · Molecular and Cellular Biology
Targeting c-Met in melanoma
Deven Etnyre, Amanda L Stone, Jason Fong, Ryan J. Jacobs, Srijayaprakash Babu Uppada, Gregory M. Botting, Supriya Rajanna, David N. Moravec, Manohar Reddy Shambannagari, Zachary David Crees et al. · 2014 · Cancer Biology & Therapy
Identification of Transmembrane Protein 88 (TMEM88) as a Dishevelled-binding Protein
Ho‐Jin Lee, David Finkelstein, Xiaofeng Li, Dianqing Wu, De‐Li Shi, Jie Zheng · 2010 · Journal of Biological Chemistry
Cyclin-Dependent Kinase 14 Promotes Cell Proliferation, Migration and Invasion in Ovarian Cancer by Inhibiting Wnt Signaling Pathway
Jun Ou-Yang, Li-Hong Huang, Xiangxiu Sun · 2016 · Gynecologic and Obstetric Investigation
Kallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6
Jingmei Zhang, Zhirong Yang, Pengfei Li, Grant Bledsoe, Lee Chao, Julie Chao · 2013 · Molecular and Cellular Biochemistry
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Dustin James Flanagan, Elizabeth Vincan, Toby James Phesse · 2017 · British Journal of Pharmacology
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LRP6 dimerization through its LDLR domain is required for robust canonical Wnt pathway activation
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Degraded Iota-Carrageenan Can Induce Apoptosis in Human Osteosarcoma Cells Via the Wnt/β-Catenin Signaling Pathway
Zhe Jin, Ya-Xin Han, Xiao-Rui Han · 2013 · Nutrition and Cancer