Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates

Means, Anna L., Meszoely, Ingrid M., Suzuki, Kazufumi, Miyamoto, Yoshiharu, Rustgi, Anil K., Coffey, Robert J., Wright, Christopher V. E., Stoffers, Doris A. +1 more·2005·Development

DOI 10.1242/dev.01925

Cited by (346)

Items 201–300 of 346

c-Jun/AP-1 is required for CCK-induced pancreatic acinar cell dedifferentiation and DNA synthesis in vitro
Lili Guo, Maria Dolors Sans, Yanan Hou, Stephen A. Ernst, John A. Williams · 2012 · American Journal of Physiology-Gastrointestinal and Liver Physiology
What are the macrophages and stellate cells doing in pancreatic adenocarcinoma?
Stephen Jacob Pandol, Mouad Edderkaoui · 2015 · Frontiers in Physiology
Context-Dependent Roles of Hes1 in the Adult Pancreas and Pancreatic Tumor Formation
Saiko Marui, Yoshihiro Nishikawa, Masahiro Shiokawa, Masataka Yokode, Shimpei Matsumoto, Yuya Muramoto, Sakiko Ota, Takeharu Nakamura, Hiroyuki K. Yoshida, Hirokazu Okada et al. · 2022 · Gastroenterology
Cell plasticity in Caenorhabditis elegans: From induced to natural cell reprogramming
Martina Hajdůšková, Arnaud Ahier, Thomas Daniele, Sophie Jarriault · 2011 · genesis
Protein Kinase C Iota Regulates Pancreatic Acinar-to-Ductal Metaplasia
Michele L. Scotti, Kristin E. Smith, Amanda Saravia-Butler, Shelly R. Calcagno, Howard C. Crawford, Michael Leitges, Alan P. Fields, Nicole R. Murray · 2012 · PLoS ONE
Acting on Hormone Receptors with Minimal Side Effect on Cell Proliferation: A Timely Challenge Illustrated with GLP-1R and GPER
Véronique Gigoux, Daniel Fourmy · 2013 · Frontiers in Endocrinology
PRDM3 attenuates pancreatitis and pancreatic tumorigenesis by regulating inflammatory response
Jie Ye, Anpei Huang, Haitao Wang, Anni M. Y. Zhang, Xiaojun Huang, Qingping Lan, Tomohiko Sato, Susumu Goyama, Mineo Kurokawa, Chu‐Xia Deng et al. · 2020 · Cell Death and Disease
Development of the Endocrine and Exocrine Pancreas
L. Murtaugh, Jared Cassiano, O. Jean-PaulDeLa · 2008 · Springer eBooks
Differentiation of Pancreatic Acinar Cells to Hepatocytes Requires an Intermediate Cell Type
Sung–Yu Wu, Chi–Che Hsieh, Ruei–Ren Wu, Jimmy Susanto, Tsung–Ta Liu, Chia‐Rui Shen, Yu Chen, Chien–Chang Su, Fang‐Pei Chang, Hsiao–Min Chang et al. · 2010 · Gastroenterology
The Quest for Tissue Stem Cells in the Pancreas and Other Organs, and their Application in Beta-Cell Replacement
Isabelle Houbracken, Luc Bouwens · 2010 · The Review of Diabetic Studies
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia
Jinmai Jiang, Hesamedin Hakimjavadi, Julie K. Bray, Corey Melissa Perkins, Alyssa Gosling, Lais daSilva, Gamze Betul Bulut, Jamel Ali, Veronica Wendy Setiawan, Martha Campbell‐Thompson et al. · 2023 · Gastro Hep Advances
Gene delivery to pancreatic exocrine cells in vivo and in vitro
Isabelle Houbracken, Luc Baeyens, Philippe Ravassard, Harry Heimberg, Luc Bouwens · 2012 · BMC Biotechnology
Organotypic Culture of Acinar Cells for the Study of Pancreatic Cancer Initiation
Alessandro Carrer, Carlotta Paoli · 2020 · Cancers
The secret origins and surprising fates of pancreas tumors
Jennifer M. Bailey, Kathleen E. DelGiorno, Howard C. Crawford · 2014 · Carcinogenesis
Dicer Is Required for Maintenance of Adult Pancreatic Acinar Cell Identity and Plays a Role in Kras-Driven Pancreatic Neoplasia
Yue Julia Wang, Florencia M. McAllister, Jennifer M. Bailey, Sherri-Gae Scott, Audrey M. Hendley, Steven D. Leach, Bidyut Ghosh · 2014 · PLoS ONE
DLG1/SAP97 modulates transforming growth factor α bioavailability
Anne-Laure Suréna, Giselle Pinto de Faria, Jeanne‐Marie Studler, Franck Peiretti, Morgane Pidoux, Jacques Camonis, Hervé Chneiweiss, Étienne Formstecher, Marie‐Pierre Junier · 2008 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Assessing the role of the EGF receptor in the development and progression of pancreatic cancer
Malcolm J. Moore, Natalie Cook, Kristopher K. Frese · 2014 · Gastrointestinal Cancer Targets and Therapy
Conversion of Human Pancreatic Acinar Cells Toward a Ductal-Mesenchymal Phenotype and the Role of Transforming Growth Factor β and Activin Signaling
Evelien De Waele, Elke Wauters, Zhidong Ling, Luc Bouwens · 2014 · Pancreas
Stem cell marker nestin is expressed in plasma cells of multiple myeloma patients
Hana Šváchová, Luděk Pour, Jiří Šáňa, L. Kovarova, Karthick Raja Muthu Raja, Roman Hájek · 2011 · Leukemia Research
Ciliogenesis and Hedgehog signalling are suppressed downstream of KRAS during acinar-ductal metaplasia in mouse
Fiona K. Bangs, Paul F. Miller, Eric E. O’Neill · 2020 · Disease Models & Mechanisms
Generation of Hydrogen Peroxide and Downstream Protein Kinase D1 Signaling Is a Common Feature of Inducers of Pancreatic Acinar-to-Ductal Metaplasia
Heike R. Döppler, Geou‐Yarh Liou, Peter Störz · 2022 · Antioxidants
Isolation and in vitro cultivation turns cells from exocrine human pancreas into multipotent stem-cells
Daniel H. Rapoport, Simone Schicktanz, Emel Gürleyik, Christine Zühlke, Charli Kruse · 2009 · Annals of Anatomy - Anatomischer Anzeiger
Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar-to-ductal metaplasia through PI3K/Akt/IKK
Xin S. Huang, Xuqi Li, Qingyong Ma, Qinhong Xu, Wanxing Duan, Jianjun Lei, Lun Zhang, Zheng Wu · 2014 · International Journal of Molecular Medicine · Retracted
β-Cell Generation: Can Rodent Studies Be Translated to Humans?
Françoise Carlotti, Arnaud Zaldumbide, Johanne H. Ellenbroek, H. Siebe Spijker, Rob C. Hoeben, Eelco J.P. de Koning · 2011 · Journal of Transplantation
Paracrine Secretion of Transforming Growth Factor β by Ductal Cells Promotes Acinar-to-Ductal Metaplasia in Cultured Human Exocrine Pancreas Tissues
Naoki Akanuma, Jun Liu, Geou‐Yarh Liou, Xue Yin, Kaitlyn Bejar, Chengyang Liu, Lu‐Zhe Sun, Peter Störz, Pei Wang · 2017 · Pancreas
Id3 modulates cellular localization of bHLH Ptf1‐p48 protein
Marlène Dufresne, Pascal Clerc, Madieng Dieng, Anissa Edir, Anne Couvelard, Marie‐Bernadette Delisle, Daniel Fourmy, Véronique Gigoux · 2010 · International Journal of Cancer
Oncogenic KRas-induced Increase in Fluid-phase Endocytosis is Dependent on N-WASP and is Required for the Formation of Pancreatic Preneoplastic Lesions
Clara Lubeseder–Martellato, Katharina Alexandrow, Ana Hidalgo‐Sastre, Irina Heid, Sophie Luise Boos, Thomas von Briel, Roland Michael Schmid, Jens Thomas Siveke · 2016 · EBioMedicine
Rat pancreatic islet is formed by unification of multiple endocrine cell clusters
Akemi Hara, Yuichi Kadoya, Itaru Kojima, Shohei Yamashina · 2007 · Developmental Dynamics
Reg genes are CCK2 receptor targets in ElasCCK2 mice pancreas
Véronique Gigoux, Pascal Clerc, Didier Sanchez, M. Coll, Helena Corominola, Stéphane Leung–Theung–Long, Luc Pénicaud, Ramón Gomis, Catherine Seva, Daniel Fourmy et al. · 2007 · Regulatory Peptides
Purified Human Pancreatic Duct Cell Culture Conditions Defined by Serum-Free High-Content Growth Factor Screening
Corinne A. Hoesli, James D. Johnson, James M. Piret · 2012 · PLoS ONE
Using CRISPR/Cas9 to Knock out Amylase in Acinar Cells Decreases Pancreatitis-Induced Autophagy
Kohei Yasunaga, Tetsuhide Ito, Masami Miki, Keijiro Ueda, Takashi Fujiyama, Yuichi Tachibana, Nao Fujimori, Ken Kawabe, Yoshihiro Ogawa · 2018 · BioMed Research International
Integrated one- and two-photon imaging platform reveals clonal expansion as a major driver of mutation load
Dominika M. Wiktor‐Brown, Hyuk-Sang Kwon, Yoon Sung Nam, Peter T. C. So, Bevin P. Engelward · 2008 · Proceedings of the National Academy of Sciences
Transmembrane and Soluble Isoforms of Heparin-Binding Epidermal Growth Factor–Like Growth Factor Regulate Distinct Processes in the Pancreas
Kevin C. Ray, Stacy A. Blaine, M. Kay Washington, Ada Braun, Amar B. Singh, Raymond Clement Harris, Paul A. Harding, Robert J. Coffey, Anna L. Means · 2009 · Gastroenterology
Identification and analysis of pancreatic intraepithelial neoplasia: opportunities and challenges
Ling-ling Pian, Mei-hui Song, Tengfei Wang, Ling Qi, Tie-li Peng, Ke-ping Xie · 2025 · Frontiers in Endocrinology
Current status of regeneration of pancreatic β‐cells
Kohtaro Minami, Susumu Seino · 2013 · Journal of Diabetes Investigation
β‐Cell replacement as a treatment for type 1 diabetes: an overview of possible cell sources and current axes of research
Andhira Vieira, Monica L. Courtney, Noémie Druelle, Fabio Avolio, Tiziana Napolitano, Biljana Hadzic, Sergi Navarro Sanz, Nouha Ben-Othman, Patrick Collombat · 2016 · Diabetes Obesity and Metabolism
Investigation and Characterization of the Duct Cell-Enriching Process During Serum-Free Suspension and Monolayer Culture Using the Human Exocrine Pancreas Fraction
Tino Klein, Yves Heremans, Harry Heimberg, DANIEL G. PIPELEERS, Ole D. Madsen, Palle Serup, R. Scott Heller · 2008 · Pancreas
Pre-neoplastic pancreas cells enter a partially mesenchymal state following transient TGF-β exposure
Jesse Stone Handler, Jane E. Cullis, Antonina Avanzi, Emily Vucic, Dafna Bar‐Sagi · 2018 · Oncogene
Encapsulation of Primary Salivary Gland Acinar Cell Clusters and Intercalated Ducts (AIDUCs) within Matrix Metalloproteinase (MMP)‐Degradable Hydrogels to Maintain Tissue Structure and Function
Yuanhui Song, Azmeer Sharipol, Hitoshi Uchida, Matthew H. Ingalls, Lindsay R. Piraino, Jared A. Mereness, Tracey Moyston, Lisa A. DeLouise, Catherine E. Ovitt, Danielle S. W. Benoit · 2022 · Advanced Healthcare Materials
NestinnegCD24low/??? Population From Fetal Nestin-EGFP Transgenic Mice Enriches the Pancreatic Endocrine Progenitor Cells
Xiaojing Wang, Jianjun Hu, Dongxin Zhao, Guangwen Wang, Lei Tan, Liying Du, Jie Yang, Lingling Hou, Hong Zhang, Yuansong Yu et al. · 2005 · Pancreas
[Reprogramming pancreatic cells to β cells].
A. Vieira, Noémie Druelle, M. Courtney, Fabio Avolio, Nouha Ben-Othman, Anja Pfeifer, Elisabet Gjernes, Biljana Faurite, P. Collombat · 2013 · Medecine sciences : M/S
On the origins and conceptual frameworks of natural plasticity—Lessons from single-cell models in C. elegans
Julien Lambert, Carla Lloret-Fernández, Lucie Laplane, Richard J. Poole, Sophie Jarriault · 2021 · Current topics in developmental biology/Current Topics in Developmental Biology
Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth
Geou‐Yarh Liou, Alicia K. Fleming Martinez, Heike R. Döppler, Ligia I. Bastea, Peter Störz · 2023 · iScience
Targeting of extracellular proteases required for the progression of pancreatic cancer
Christine Ardito-Abraham, Courtney D Briggs, Howard C. Crawford · 2008 · Expert Opinion on Therapeutic Targets
Cellular plasticity of the pancreas
Luc Baeyens, Luc Bouwens · 2009 · Biological Chemistry
Prox1-Heterozygosis Sensitizes the Pancreas to Oncogenic Kras-Induced Neoplastic Transformation
Y. Drosos, G. Neale, Jianming Ye, Leena Paul, Emin Kuliyev, A. Maitra, A. Means, M. Washington, J. Rehg, David B. Finkelstein et al. · 2016 · Neoplasia
Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression
Maria Petropavlovskaia, Julia Makhlin, John S. Sampalis, Lawrence C. Rosenberg · 2006 · Journal of Endocrinology
Subtype Transdifferentiation in Human Cancer: The Power of Tissue Plasticity in Tumor Progression
Monica Fedele, Laura Cerchia, Sabrina Battista · 2024 · Cells
Plasticity and Tumor Microenvironment in Pancreatic Cancer: Genetic, Metabolic, and Immune Perspectives
Ari Hashimoto, Shigeru Hashimoto · 2024 · Cancers
Local hyperthyroidism promotes pancreatic acinar cell proliferation during acute pancreatitis
Ermanno Malagola, Rong Chen, Marta Bombardo, Enrica Saponara, Monica Dentice, Domenico Salvatore, Theresia Reding, Stephen Myers, Andrew Peter Hills, Rolf Graf et al. · 2019 · The Journal of Pathology
Oreocnide integrifoliaFlavonoids Augment Reprogramming for Islet Neogenesis andβ-Cell Regeneration in Pancreatectomized BALB/c Mice
Md Ansarullah, Bhavna Bharucha, Malati Umarani, Mitesh Dwivedi, Naresh C. Laddha, Rasheedunnisa Begum, Anandwardhan A. Hardikar, A. V. Ramachandran · 2012 · Evidence-based Complementary and Alternative Medicine
Deciphering cellular plasticity in pancreatic cancer for effective treatments
Md. Hafiz Uddin, Dingqiang Zhang, Irfana Muqbil, Bassel F. El‐Rayes, Herbert Chen, Philip A. Philip, Asfar Sohail Azmi · 2024 · Cancer and Metastasis Reviews
NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming
Zhe Zhang, Xin Wang, Feda H. Hamdan, Anna Likhobabina, Shilpa Patil, Lena Aperdannier, Madhobi Sen, Jacobe Traub, Albrecht Neeße, André Fischer et al. · 2023 · Cellular and Molecular Gastroenterology and Hepatology
Loss of Wasl improves pancreatic cancer outcome
Ana Hidalgo‐Sastre, Judit Desztics, Zahra Dantes, Katharina Schulte, Hilal Kabadayı, Blessing Iquo Bassey-Archibong, Rupert Öllinger, Thomas Engleiter, Lyndsay G. A. Rayner, Henrik Einwächter et al. · 2020 · JCI Insight
Current Stem Cell Technology: Limitations and Realistic Expectations
Charli Kruse, Sandra Danner, Daniel H. Rapoport · 2008 · Engineering in Life Sciences
Clinical significance of pancreatic ductal metaplasia
Tingting Jiang, Wei Fang, Keping Xie · 2022 · The Journal of Pathology
Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis
Andrea Costamagna, Dora Natalini, Maria del Pilar Camacho Leal, Matilde Simoni, Luca Gozzelino, Paola Cappello, Francesco Novelli, Chiara Ambrogio, Paola Defilippi, Emilia Turco et al. · 2021 · Gastroenterology
p53 inhibitor iASPP is an unexpected suppressor of KRAS and inflammation-driven pancreatic cancer
Paul Miller, Elliot H. Akama‐Garren, Richard Peter Owen, Constantinos Demetriou, Thomas M. Carroll, Elizabeth A. Slee, Khatoun Al Moussawi, Michael Ellis, Robert David Goldin, Eric E. O’Neill et al. · 2023 · Cell Death and Differentiation
How can we get more beta cells?
Akari Inada, Susan Bonner‐Weir, Elena Toschi · 2006 · Current Diabetes Reports
Differentiation of CD24− pancreatic ductal cell‐derived cells into insulin‐secreting cells
Chunyou Wang, Shanmiao Gou, Tao Liu, Heshui Wu, Jiongxin Xiong, Feng Zhou, Jing Tao · 2008 · Development Growth & Differentiation
Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice
Kozo Ikuta, A. Fukuda, Satoshi Ogawa, K. Masuo, N. Goto, Y. Hiramatsu, Motoyuki Tsuda, Y. Kimura, Y. Matsumoto, Yuto Kimura et al. · 2018 · Gut
Present Accomplishments and Future Prospects of Cell-Based Therapies for Type 1 Diabetes Mellitus
Preeti Chhabra, Daniel L Clark, Daniel J., L. Bost Kenneth · 2011 · InTech eBooks
Reversal of Diabetes in Rats Using GLP-1-Expressing Adult Pancreatic Duct-Like Precursor Cells Transformed From Acinar to Ductal Cells
Jieun Lee, Jing Wen, Jeong Youp Park, Sun A Kim, Eun Jig Lee, Si Young Song · 2009 · Stem Cells and Development
Sca-1 is a marker for cell plasticity in murine pancreatic epithelial cells and induced by IFN-β in vitro
Georg Leinenkugel, Bo Kong, Susanne Raulefs, Katharina Miller, Susanne Roth, Hongdie Jiang, Rouzanna Istvánffy, Hanna Heikenwälder, Nadja Maeritz, Ivonne Regel et al. · 2022 · Pancreatology
NADPH-producing enzymes restrict the formation of pancreatic precancerous lesions
Megan D. Radyk, Barbara Scott Nelson, Mariana T. Ruckert, Christopher J. Halbrook, Mengrou Shan, Jonathan M. Alektiar, Brooke L. Lavoie, Lucie Salvatore, Wei Yan, Matthew D. Perricone et al. · 2026 · Nature Metabolism
Molecular signaling in pancreatic ductal metaplasia: emerging biomarkers for detection and intervention of early pancreatic cancer
Xiaojia Li, Jie He, Keping Xie · 2022 · Cellular Oncology
Pancreatic cells and their progenitors.
S. Salpeter, Y. Dor · 2006 · Methods in Enzymology
Acinar Ductal Metaplasia: Yap Fills a Gap
Anna L. Means, Craig D. Logsdon · 2016 · Gastroenterology
Optimizing Soluble Cues for Salivary Gland Tissue Mimetics Using a Design of Experiments (DoE) Approach
Lindsay R. Piraino, Danielle S. W. Benoit, Lisa A. DeLouise · 2022 · Cells
Inflammation and Cancer Development in Pancreatic and Biliary Tract Cancer
Sang Hoon Lee, Seung Woo Park · 2015 · Korean Journal of Gastroenterology
Inactivation of Notch4 Attenuated Pancreatic Tumorigenesis in Mice
Kiyoshi Saeki, Wanglong Qiu, Richard A. Friedman, Samuel S. Pan, Jordan Lu, Shu Ichimiya, Iok In Christine Chio, Carrie J. Shawber, Jan Kitajewski, Jianhua Hu et al. · 2022 · Cancer Research Communications
Pharmacological Modulation of Apoptosis and Autophagy in Pancreatic Cancer Treatment
Johnson Stanslas, Mohammad Kaisarul Islam, Nityaa Selvarajoo, Sreenivasa Rao Sagineedu, Kok Lian Ho, Jonathan Chee Woei Lim · 2022 · Mini-Reviews in Medicinal Chemistry
De Novo Generation of Somatic Stem Cells by YAP/TAZ
Tito Panciera, Luca Azzolin, Daniele Di Biagio, Antonio Totaro, Michelangelo Cordenonsi, Stefano Piccolo · 2018 · Journal of Visualized Experiments
Macrophage-induced reactive oxygen species in the initiation of pancreatic cancer: a mini-review
Heike R. Döppler, Peter Störz · 2024 · Frontiers in Immunology
Isolation, Culture and Differentiation of Primary Acinar Epithelial Explants from Adult Murine Pancreas
Clara Lubeseder–Martellato · 2013 · BIO-PROTOCOL
Pancreatic β-Cell Mass as a Pharmacologic Target in Diabetes
Stephen C. Hanley · 2020 · McGill Journal of Medicine
Metaplastic Metamorphoses in the Mammalian Pancreas
Stephen F. Konieczny, Steven D. Leach · 2007 · Gastroenterology
Experimental acute pancreatitis: In vitro models
Olga A. Mareninova · 2015
Molecular dynamics driving phenotypic divergence among KRAS mutants in pancreatic tumorigenesis
A. Grimont, David Falvo, W. Sisso, Francisco Santos, Christopher W. Chan, P. Zumbo, William B. Fall, Katherine R. Ferrick, Grace Pan, M. Cleveland et al. · 2026 · Developmental Cell
Utility of Animal Models in Pancreatic Cancer Research
Asfar Sohail Azmi, Mussop Mohammad, Ahmed Omar Kaseb, Fazlul H. Sarkar, Ramzi M. Mohammad · 2008 · Springer eBooks
Prolactin Increases Expression of Cytoskeletal Proteins in SK-N-SH Cells
Tomáš Havránek, Zuzana Bačová, Vladimír Štrbák, Zuzana Lestanova, Ján Bakoš · 2014 · Folia Biologica
MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions
Elyne Backx, Elke Wauters, Jonathan Baldan, Mathias Van Bulck, Ellis Michiels, Yves Heremans, Diedert Luc De Paep, Mineo Kurokawa, Susumu Goyama, Luc Bouwens et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression
Asmi Chakraborty, Nikita Bhalerao, Michael P. Marciel, Jihye Hwang, Colleen M. Britain, Isam Eltoum, Robert B. Jones, Katie L. Alexander, Lesley E. Smythies, Phillip D. Smith et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
Lineage-Specific Transcription Factors in Carcinogenesis
Charles J. David, Sakari Vanharanta · 2024 · Annual Review of Cancer Biology
Allelic effects on KLHL17 expression underlie a pancreatic cancer genome-wide association signal at chr1p36.33
Katelyn E. Connelly, Katherine Hullin, Ehssan Abdolalizadeh, Jun Zhong, Daina Eiser, Aidan O’Brien, Irene J. Collins, Sudipto Das, Gerard Duncan, Demetrius Albanes et al. · 2025 · Nature Communications
Expression of the Stem Cell Marker Nestin in Response to Tissue Injuries of Parotid Acinar Cells
Megumi Yokoyama, Hiroaki Ogawa, Osamu Katsumata-Kato, Junko Fujita‐Yoshigaki · 2017 · International Journal of Oral-Medical Sciences
Protein kinase D1 — A targetable mediator of pancreatic cancer development
Alicia K. Fleming Martinez, Peter Störz · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
RACK1 attenuates pancreatic tumorigenesis by suppressing acinar-to-ductal metaplasia through inflammatory signaling modulation
Wei Zhang, Tingting Jiang, Huiqing Zhang, Wei Fang, Xiaojia Li, Keping Xie · 2025 · Cellular Oncology
Normal Pancreatic Development
K. D. Henley, M. Gannon · 2014 · Elsevier eBooks
Generation of Beta Cells from Acinar Cells
Luc Baeyens, Ilse Rooman, Luc Bouwens · 2009 · Humana Press eBooks
Insights into the Development of Preneoplastic Metaplasia: Spasmolytic Polypeptide-Expressing Metaplasia and Oxyntic Atrophy
James R. Goldenring, Sachiyo Nomura · 2009 · Springer eBooks
Hyaluronan in the Extracellular Matrix of Hematological and Solid Tumors. Its Biological Effects
Antonella Icardi, Silvina Laura Lompardía, Daniela Laura Papademetrio, Paolo Rosales, Mariángeles Díaz, Matías Arturo Pibuel, Laura Daniela Alaniz, Elida E. Alvarez · 2022 · Biology of extracellular matrix
Rosa26-GFP Direct Repeat (RaDR-GFP) Mice Reveal Tissue- and Age-Dependence of Homologous Recombination in Mammals In Vivo
Michelle R. Sukup-Jackson, Orsolya Kiraly, Jennifer E. Kay, Li Na, Elizabeth A. Rowland, Kelly E. Winther, Danielle N. Chow, Takafumi Kimoto, Tetsuya Matsuguchi, Vidya S. Jonnalagadda et al. · 2014 · PLoS Genetics
PRRX1 Has Functional Roles in Pancreatic Acinar to Ductal Metaplasia and Carcinogenesis
Noriyuki Nishiwaki, Kensuke Sugiura, Kensuke Suzuki, Alina L. Li, Constanza Tapia Contreras, Gizem Efe, Alice E. Shin, Dorsay Sadeghian, Jun Zhao, Anirban Maitra et al. · 2024 · Cellular and Molecular Gastroenterology and Hepatology
Infrared Imaging Combined with Machine Learning for Detection of the (Pre)Invasive Pancreatic Neoplasia
Danuta Liberda, Kinga B. Stopa, Daria Krzysztofik, Paweł E. Ferdek, Monika Joanna Jakubowska, Tomasz P. Wróbel · 2025 · ACS Pharmacology & Translational Science
A single-cell multi-omic atlas of the human pancreas reveals potential for cellular plasticity across development, health, and disease
Elisabetta Mereu, Diego Balboa, Johannes Liebig, Aitor Gonzalez, Anna Martinez Casals, Mariya Mardamshina, Fanny Mollandin, Felix Schicktanz, Alexander Sudy, Luca Tosti et al. · 2026 · Cell Metabolism
Heterogeneity and Plasticity of Multiple Myeloma
Hana Šváchová, Sabina Ševčı́ková, Roman Hájek · 2013 · InTech eBooks
Models of Regeneration of Beta Cells in Vivo
Ioana Rada Popa Ilie, Razvan Ilie · 2013
The oncofetal protein IMP1 regulates the transcriptomic landscape to drive early events in pancreatic cancer progression and growth
Orçun Haçarız, Julia Messina‐Pacheco, Elliot Goodfellow, Matthew Leibovitch, Andrew M. Lowy, Stéphanie Perrino, Bertrand J. Jean‐Claude, Zu‐Hua Gao, Alex Gregorieff, Pnina Brodt · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Pancreatic Progenitor Cells in Injury and Regeneration
Solomon Afelik, J. Jensen · 2008 · Springer eBooks