The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Regulation of early lung morphogenesis: questions, facts and controversies
Open accessAbstract
During early respiratory system development, the foregut endoderm gives rise to the tracheal and lung cell progenitors. Through branching morphogenesis, and in coordination with vascular development, a tree-like structure of epithelial tubules forms and differentiates to produce the airways and alveoli. Recent studies have implicated the fibroblast growth factor, sonic hedgehog, bone morphogenetic protein, retinoic acid and Wnt signaling pathways, and various transcription factors in regulating the initial stages of lung development. However, the precise roles of these molecules and how they interact in the developing lung is subject to debate. Here, we review early stages in lung development and highlight questions and controversies regarding their molecular regulation.
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Citations
Cites
Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas
Bort, R., Martinez-Barbera, J. P., Beddington, R. S. P., & Zaret, K. S. (2004) · Development · doi:10.1242/dev.00965 · Cited by 267 · cited 1×
“Exposure of the endoderm to diffusible signals from these structures at crucial developmental windows is essential for endodermal cell fate specification (Kumar and Melton, 2003; Bort et al., 2004).”
Background
Cited by
Preparing for the First Breath: Genetic and Cellular Mechanisms in Lung Development
Morrisey, E. E., & Hogan, B. L. M. (2010) · Developmental Cell · doi:10.1016/j.devcel.2009.12.010 · Cited by 964
Vertebrate Endoderm Development and Organ Formation
Zorn, A. M., & Wells, J. M. (2009) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.042308.113344 · Cited by 812
Lung development: orchestrating the generation and regeneration of a complex organ
Herriges, M., & Morrisey, E. E. (2014) · Development · doi:10.1242/dev.098186 · Cited by 613
Somers, A., Jean, J.-C., Sommer, C. A., Omari, A., Ford, C. C., Mills, J. A., Ying, L., Sommer, A. G., Jean, J. M., Smith, B. W., et al. (2010) · Stem Cells · doi:10.1002/stem.495 · Cited by 423
Efficient Derivation of Purified Lung and Thyroid Progenitors from Embryonic Stem Cells
Longmire, T. A., Ikonomou, L., Hawkins, F., Christodoulou, C., Cao, Y., Jean, J. C., Kwok, L. W., Mou, H., Rajagopal, J., Shen, S. S., et al. (2012) · Cell Stem Cell · doi:10.1016/j.stem.2012.01.019 · Cited by 384
Metadata
- Authors
- Cardoso, W. V., & Lü, J.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2006-05-01
- Volume
- 133
- Issue
- 9
- Pages
- 1611-1624
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2001508112
- Cited by
- 585
- References
- 1
- FWCI
- 36.49
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Cardoso, W. V., & Lü, J. (2006). Regulation of early lung morphogenesis: questions, facts and controversies. Development. https://doi.org/10.1242/dev.02310
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