HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells

DeLaForest, Ann, Nagaoka, Masato, Si-Tayeb, Karim, Noto, Fallon K., Konopka, Genevieve, Battle, Michele A., Duncan, Stephen A.·2011·Development
DOI 10.1242/dev.062547

Cited by (219)

Items 101–200 of 219

  1. Profiling of Embryonic Stem Cell Differentiation
    Nobuaki Shiraki, Soichiro Ogaki, Shoen Kume · 2014 · The Review of Diabetic Studies
  2. EpiCompare: an online tool to define and explore genomic regions with tissue or cell type-specific epigenomic features
    Yu He, Ting Wang · 2017 · Bioinformatics
  3. LINC00483 Has a Potential Tumor-Suppressor Role in Colorectal Cancer Through Multiple Molecular Axes
    Duilia Brex, Cristina Barbagallo, Federica Mirabella, Angela Caponnetto, Rosalia Battaglia, Davide Barbagallo, Rosario Caltabiano, Giuseppe Broggi, Lorenzo Memeo, Cinzia Di Pietro et al. · 2021 · Frontiers in Oncology
  4. Hepatocyte Nuclear Factor 4 Alpha Promotes Definitive Endoderm Differentiation from Human Induced Pluripotent Stem Cells
    Morifumi Hanawa, Kazuo Takayama, Fuminori Sakurai, Masashi Tachibana, Hiroyuki Mizuguchi · 2016 · Stem Cell Reviews and Reports
  5. In Vitro Pluripotent Stem Cell Differentiation to Hepatocyte Ceases Further Maturation at an Equivalent Stage of E15 in Mouse Embryonic Liver Development
    Ravali Raju, David Chau, Tineke Notelaers, Chad L. Myers, Catherine M. Verfaillie, Wei‐Shou Hu · 2018 · Stem Cells and Development
  6. HNF4α is possibly the missing link between epithelial–mesenchymal transition and Warburg effect during hepatocarcinogenesis
    Bahareh Shokouhian, Babak Negahdari, Zahra Heydari, Mehdi Totonchi, Hamidreza Aboulkheyr Es, Abbas Piryaei, Ebrahim Mostafavi, Massoud Vosough · 2022 · Cancer Science
  7. Deconvolving sequence features that discriminate between overlapping regulatory annotations
    A. Kakumanu, Silvia Velasco, E. Mazzoni, Shaun Mahony · 2017 · bioRxiv
  8. Hepatic population derived from human pluripotent stem cells is effectively increased by selective removal of undifferentiated stem cells using YM155
    Seok Jin Kang, Young-Il Park, So‐Ryeon Hwang, Hee Yi, Nga Thi Thu Tham, Hyun‐Ok Ku, Jae‐Young Song, Hwan‐Goo Kang · 2017 · Stem Cell Research & Therapy
  9. Aneuploidy is permissive for hepatocyte-like cell differentiation from human induced pluripotent stem cells
    Fallon K. Noto, Megan R. Determan, Jun Cai, Max A. Cayo, Sunil K. Mallanna, Stephen A. Duncan · 2014 · BMC Research Notes
  10. Hepatocyte-like cells differentiated from human induced pluripotent stem cells (iHLCs) are permissive to hepatitis C virus (HCV) infection: HCV study gets personal
    Karim Si‐Tayeb, Jean‐Charles Duclos‐Vallée, Marie-Anne Petit · 2012 · Journal of Hepatology
  11. Inhibition of hepatocyte nuclear factor 1 and 4 alpha (HNF1α and HNF4α) as a mechanism of arsenic carcinogenesis
    Anna Pastoret, Ricard Marcos, Adriana Sampayo‐Reyes, Odila Saucedo Cárdenas, Gerardo Lozano-Garza, Alba Hernández · 2012 · Archives of Toxicology
  12. CXCR7 correlates with the differentiation of hepatocellular carcinoma and suppresses HNF4α expression through the ERK pathway
    Tong‐Chun Xue, Qingan Jia, Yang Bu, Rongxin Chen, Jiefeng Cui, Zhao–You Tang, Sheng‐Long Ye · 2014 · Oncology Reports
  13. New Tools in Experimental Cellular Therapy for the Treatment of Liver Diseases
    Jennifer R. Ferrer, Attasit Chokechanachaisakul, Jason A. Wertheim · 2015 · Current Transplantation Reports
  14. Multiomics Analyses of HNF4α Protein Domain Function during Human Pluripotent Stem Cell Differentiation
    Yu Wang, Michael H. Tatham, Wolfgang Schmidt‐Heck, Carolyn J. Swann, Karamjit Singh Dolt, Jose Meseguer-Ripolles, Baltasar Lucendo‐Villarin, Tilo Kunath, Timothy Robert Rudd, Andrew J.H. Smith et al. · 2019 · iScience
  15. Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model
    Myung Rae Park, Man Sze Wong, Marcos Jesus Araúzo-Bravo, Hyun-Ah Lee, Donggyu Nam, Soo Yong Park, Hong Dae Seo, Sang Min Lee, Hans Florian Zeilhofer, Holm Zaehres et al. · 2019 · PLoS ONE
  16. FOXA1 /2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell‐derived hepatic progenitor cells
    Iyan Warren, Michael M. Moeller, Daniel Guiggey, Alexander Chiang, Mitchell H. Maloy, Ogechi Ogoke, Theodore Groth, Tala Mon, Saber Meamardoost, Xiaojun Liu et al. · 2022 · The FASEB Journal
  17. Single-step protocol for the differentiation of human-induced pluripotent stem cells into hepatic progenitor-like cells
    M. Tomizawa, Fuminobu Shinozaki, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi, Takanobu Yoshida · 2012 · Biomedical Reports
  18. Effect of sex-specific differences on function of induced hepatocyte-like cells generated from male and female mouse embryonic fibroblasts
    Imran Ullah, Yurianna Shin, Yeongji Kim, Keon Bong Oh, Seongsoo Hwang, Young-Im Kim, Jeong-Woong Lee, Tai‐Young Hur, Seunghoon Lee, Kangmin Seo et al. · 2021 · Stem Cell Research & Therapy
  19. Induced Endothelial Cell-Integrated Liver Assembloids Promote Hepatic Maturation and Therapeutic Effect on Cholestatic Liver Fibrosis
    Donggyu Nam, Myung Rae Park, Hyun-Ah Lee, Sung Chul Bae, Daniela Gerovska D, Marcos Jesus Araúzo-Bravo, Holm Zaehres, Hans Robert Schöler, Jeong Beom Kim · 2022 · Cells
  20. A genome-wide interactome of DNA-associated proteins in the human liver
    Ryne C. Ramaker, Daniel Savic, Andrew A. Hardigan, Kimberly M. Newberry, Gregory M. Cooper, R Myers, Sara J. Cooper · 2017 · Genome Research
  21. C9ORF135 encodes a membrane protein whose expression is related to pluripotency in human embryonic stem cells
    Shixin Zhou, Yinan Liu, Yumin Ma, Xiaoyan Zhang, Yang Li, Jinhua Wen · 2017 · Scientific Reports
  22. Validating Well-Functioning Hepatic Organoids for Toxicity Evaluation
    Seo Yoon Choi, Tae Hee Kim, Min Jeong Kim, Seon Ju Mun, Taesung Kim, Ki Kyung Jung, Il Ung Oh, Jae Ho Oh, Myung Jin Son, Jin Hee Lee · 2024 · Toxics
  23. Identification of Hepatic-like EPO as a Cause of Polycythemia
    Laurent Martin, Darko Maric, Salam Idriss, Marine Delamare, Amandine Le Roy, Nada Maaziz, Amandine Caillaud, Karim Si‐Tayeb, Florence Robriquet, Marion Lenglet et al. · 2025 · New England Journal of Medicine
  24. Pluripotent Stem Cell-Derived Hepatocytes Inhibit T Cell Proliferation In Vitro through Tryptophan Starvation
    Marco Romano, Raúl Elgueta, Daniel McCluskey, Ana Maria Ortega‐Prieto, Émilie Stolarczyk, Francesco Dazzi, Baltasar Lucendo‐Villarin, Jose Meseguer-Ripolles, James H. Williams, Giorgia Fanelli et al. · 2021 · Cells
  25. Controversial roles of hepatocyte nuclear receptor 4 α on tumorigenesis (Review)
    Zhu Wang, Ying Zhang, Jianwen Zhang, Qiong Deng, Hui Liang · 2021 · Oncology Letters
  26. Human induced pluripotent stem cell derived hepatocytes provide insights on parenteral nutrition associated cholestasis in the immature liver
    T. Hang Nghiem‐Rao, Courtney Pfeifer, Michelle Asuncion, Joshua A. Nord, Daniel Schill, Kirthi Pulakanti, Shailendra B. Patel, Lisa Ann Cirillo, Sridhar Rao · 2021 · Scientific Reports
  27. Transcription regulatory codes of eukaryotic genomes
    Tatiana I. Merkulova, Elena A. Ananko, Elena V. Ignatieva, Nikolay Alexandrovich Kolchanov · 2013 · Russian Journal of Genetics
  28. Downregulation of the NF-κB protein p65 is a shared phenotype among most anti-aging interventions
    Ahmed M. Elmansi, Abraham Kassem, Rafael M. Castilla, Richard A. Miller · 2024 · GeroScience
  29. Expression of Putative Stem Cell Marker, Hepatocyte Nuclear Factor 4 Alpha, in Mammary Gland of Water Buffalo
    Ratan K. Choudhary, Shanti Choudhary, Harmanjot Kaur, Devendra Pathak · 2016 · Animal Biotechnology
  30. Hepatogenic Supported Differentiation of Mesenchymal Stem Cells in a Lactobionic Acid-Conjugated Thermogel
    Hyo Jung Moon, Hyun Jung Lee, Madhumita Patel, Sohee Park, Seo Hee Chang, Byeongmoon Jeong · 2017 · ACS Macro Letters
  31. Development of Bifunctional Three-Dimensional Cysts from Chemically Induced Liver Progenitors
    Yu Guang Huang, Yusuke Sakai, Takanobu Hara, Takeshi Katsuda, Takahiro Ochiya, Tomohiko Adachi, Masaaki Hidaka, Weili Gu, Susumu Eguchi · 2019 · Stem Cells International
  32. Nuclear receptor gene alteration in human induced pluripotent stem cells with hepatic differentiation propensity
    Noriko Itaba, Peninah M. Wairagu, Natsumi Aramaki, Toshihiro Yasui, Yoshiaki Matsumi, Yohei Kono, Ai N. H. Phan, Makoto Otsu, Takahiro Kunisada, Yukio Nakamura et al. · 2014 · Hepatology Research
  33. Hepatocyte differentiation from mouse liver ductal organoids by transducing 4 liver-specific transcription factors
    Katsuhiro Tomofuji, Jumpei Kondo, Kunishige Onuma, Roberto Coppo, Hiroshi Horie, Koki Oyama, Eiji Miyoshi, Ken Fukumitsu, Takamichi Ishii, Etsuro Hatano et al. · 2023 · Hepatology Communications
  34. Signaling molecules orchestrating liver regenerative medicine
    Nima Zakeri, Elnaz Sadat Mirdamadi, Dianoosh Kalhori, Mehran Solati‐Hashjin · 2020 · Journal of Tissue Engineering and Regenerative Medicine
  35. How transient becomes stable: An epigenetic switch linking liver inflammation and tumorigenesis
    Stefano Cairo, Marie Annick Buendia · 2012 · Journal of Hepatology
  36. Differentiation of human foreskin fibroblast‐derived induced pluripotent stem cells into hepatocyte‐like cells
    Jianjun Wang, Ping Zhao, Zhihong Wan, Xueyuan Jin, Yongqian Cheng, Tao Yan, Song Qing, Ning Ding, Shaojie Xin · 2016 · Cell Biochemistry and Function
  37. Signaling and Gene Regulatory Networks Governing Definitive Endoderm Derivation From Pluripotent Stem Cells
    Abdulshakour Mohammadnia, Moein Yaqubi, Farzaneh Pourasgari, Eric J. Neely, Hossein Fallahi, Mohammad Massumi · 2016 · Journal of Cellular Physiology
  38. Functional Blood Progenitor Markers in Developing Human Liver Progenitors
    Orit Goldman, Idan Cohen, Valerie Gouon–Evans · 2016 · Stem Cell Reports
  39. Generation of carbamoyl phosphate synthetase 1 reporter cell lines for the assessment of ammonia metabolism
    Yi Wang, Le Chang, Jiahui Zhai, Qiao Wu, Donggen Wang, Yunfang Wang · 2017 · Journal of Cellular and Molecular Medicine
  40. Differentiation of human pluripotent stem cells toward pharyngeal endoderm derivatives: Current status and potential
    Margaret E. Magaletta, Richard Siller, René Maehr · 2020 · Current topics in developmental biology/Current Topics in Developmental Biology
  41. LOC100996425 acts as a promoter in prostate cancer by mediating hepatocyte nuclear factor 4A and the AMPK/mTOR pathway
    Xiuyan Wang, Bin Song, Mingcui Zang, He Ji, Yang He, Shuang Jiang, Xiao Yang · 2021 · Journal of Cellular and Molecular Medicine
  42. The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics
    Bani Mukhopadhyay, Kellie Holovac, Kornel E. Schuebel, Partha Mukhopadhyay, Reşat Çınar, Sindhu Iyer, Cheryl A. Marietta, David A Goldman, George Kunos · 2023 · Cell Death Discovery
  43. Dual Gene Expression in Embryoid Bodies Derived from Human Induced Pluripotent Stem Cells Using Episomal Vectors
    M. Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi · 2014 · Tissue Engineering Part A
  44. Embryonic Development of the Liver
    Roque Bort, Kenneth S. Zaret · 2009 · Wiley eBooks
  45. LncRNAs are involved in regulating ageing and age-related disease through the adenosine monophosphate-activated protein kinase signalling pathway
    Jiamei Li, Feng Xiao, Siqi Wang, Xiaolan Fan, Zhi He, Taiming Yan, Jia Zhang, Mingyao Yang, Deying Yang · 2023 · Genes & Diseases
  46. Role of Hepatic-Specific Transcription Factors and Polycomb Repressive Complex 2 during Induction of Fibroblasts to Hepatic Fate
    Shima Rastegar‐Pouyani, Niusha Khazaei, Ping Wee, Abdulshakour Mohammadnia, Moein Yaqubi · 2016 · PLoS ONE
  47. Molecular subtyping and characterization of clear cell renal cell carcinoma by tumor differentiation trajectories
    Xiuwu Pan, Wenjin Chen, Da Xu, Wenbin Guan, Lin Li, Jiaxin Chen, Weijie Chen, Keqin Dong, Jianqing Ye, Sishun Gan et al. · 2023 · iScience
  48. Modeling population size independent tissue epigenomes by ChIL‐seq with single thin sections
    Kazumitsu Maehara, Kosuke Tomimatsu, Akihito Harada, Kaori Y. Tanaka, Shoko Sato, Megumi FUKUOKA, Seiji Okada, Tetsuya Handa, Hitoshi Kurumizaka, Noriko Saitoh et al. · 2021 · Molecular Systems Biology
  49. Hepatocyte selection medium eliminating induced pluripotent stem cells among primary human hepatocytes
    M. Tomizawa · 2015 · World Journal of Methodology
  50. Tumor supernatant derived from hepatocellular carcinoma cells treated with vincristine sulfate have therapeutic activity
    Yan Zhong, Huanli Qi, Xuejiao Li, Mengyang An, Qing‐Wen Shi, Jinsheng Qi · 2020 · European Journal of Pharmaceutical Sciences
  51. Generation of Hepatocyte-Like Cells from Human Pluripotent Stem Cells
    Fallon K. Noto, Stephen A. Duncan · 2013 · Springer eBooks
  52. Transposable element exaptation is the primary source of novelty in the primate gene regulatory landscape
    Marco Trizzino, YoSon Park, Márcia Holsbach Beltrame, Katherine A Aracena, Katelyn M. Mika, Minal Çalışkan, George H. Perry, Vincent J. Lynch, Christopher D. Brown · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
  53. Hepatocyte nuclear factor 4-Alpha: a key regulator in liver carcinogenesis
    Hayam Hamdy, Chang Shen, Jiashun Xu, Die Fan, Yiwen Zhang, Hui Li, Yonglong Wei, Jianwei Sun · 2025 · Cellular Oncology
  54. Bioinformatics analysis to screen key genes implicated in the differentiation of induced pluripotent stem cells to hepatocytes
    Rui Lin, Yufeng Wang, Kun Ji, Zhongyan Liu, Shuai Xiao, Dehua Zhou, Quanning Chen, Baomin Shi · 2018 · Molecular Medicine Reports
  55. Liver gene regulatory networks: Contributing factors to nonalcoholic fatty liver disease
    Inês Cebola · 2020 · WIREs Systems Biology and Medicine
  56. Improved Survival and Initiation of Differentiation of Human Induced Pluripotent Stem Cells to Hepatocyte-Like Cells upon Culture in William’s E Medium followed by Hepatocyte Differentiation Inducer Treatment
    M. Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige · 2016 · PLoS ONE
  57. HNF4A is essential for specification of hepatic progenitors from human pluripotent stem cells
    Ann DeLaForest, Masato Nagaoka, Karim Si‐Tayeb, Fallon K. Noto, Geneviève Konopka, Michele A. Battle, Stephen A. Duncan · 2011 · Journal of Cell Science
  58. Tumour development following internal exposures to radionuclides during the perinatal period.
    M.R. Sikov · 1989 · PubMed
  59. Multi-dimensional profiling of hepatoblastomas and patient-derived tumor organoids uncovers tumor subpopulations with divergent WNT activation profiles and identifies pan-hepatoblastoma drug sensitivities
    Thomas A. Kluiver, Yuyan Lu, Stephanie A. Schubert, Lianne J. Kraaier, Femke C. A. S. Ringnalda, Philip Lijnzaad, Jeff DeMartino, Wout Megchelenbrink, Vicky Amo-Addae, Selma Eising et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  60. A single-cell chromatin accessibility dataset of human primed and naïve pluripotent stem cell-derived teratoma
    Jin-Xiu Li, Li-Xin Fu, Yun-Pan Li, Wei Sun, Yao Yi, Wen-Qi Jia, Hai-Wei Li, Hao Liu, Peng-Cheng Guo, Yang Wang et al. · 2024 · Scientific Data
  61. Single-cell multi-omics delineates the dynamics of distinct epigenetic codes coordinating mouse gastrulation
    Mingzhu Fu, Long Pang, Zhenwei Wu, Mei Wang, Jin Jin, Shanshan Ai, Xin Li · 2025 · BMC Genomics
  62. Human Liver Organoids as an Experimental Tool to Investigate Lipocalin-2 in Hepatic Inflammation
    Katja Hardt, Robert F. Pohlberger, Diandra T. Keller, Eva Miriam Buhl, Florian W. R. Vondran, Anjali A. Roeth, Ralf Weiskirchen, Sarah K. Schröder · 2026 · Cells
  63. PCK1 attenuates tumor stemness via activating the Hippo signaling pathway in hepatocellular carcinoma
    Rui R Liu, Liu Yi, Wenlu Zhang, Guiji Zhang, Zhirong Zhang, Luyi Huang, Ni Tang, Kai Wang · 2023 · Genes & Diseases
  64. Therapeutic potential of stem cell‐derived somatic cells to treat metabolic dysfunction‐associated steatotic liver disease and diabetes
    Eduardo Hideo Gilglioni, Mayank Bansal, Wadsen St‐Pierre‐Wijckmans, Stephanie Talamantes, Alvile Kasarinaite, David C. Hay, Esteban N. Gurzov · 2025 · Obesity Reviews
  65. Differential Control of Growth and Identity by HNF4α Isoforms in Pancreatic Ductal Adenocarcinoma
    Pengshu Fang, Emily R. Wilson, Sydney N. Larsen, Walter A. Orellana, Margaret A Hall, Chris Stubben, Acramul Haque Kabir, Kajsa E. Affolter, Richard A. Moffitt, Xiaoyang Zhang et al. · 2025 · Molecular Cancer Research
  66. Generation of Hepatic Progenitor Cells from the Primary Hepatocytes of Nonhuman Primates Using Small Molecules
    Da Hee Hong, Changhee Lee, Yohan Kim, Seung Bum Lee, Su-Cheol Han, Sung Joo Kim, Heung‐Mo Yang, Dongho Choi, Jaemin Jeong, Ki‐Young Ryu · 2021 · Tissue Engineering and Regenerative Medicine
  67. Targeting the hepatic circadian clock concomitant with tyrosine kinase inhibition reverses late-stage hepatocellular carcinoma
    Baharan Fekry, Savera Aggarwal, Rachel Van Drunen, Rafael Bravo, Andy Escalante, Constance Lynn Atkins, Sheng Pan, Zheng Chen, Kai Sun, David R. Hall et al. · 2025 · Cell Reports
  68. Abundant repressor binding sites in human enhancers are associated with the fine-tuning of gene regulation
    Wei Song, Ivan Ovcharenko · 2024 · iScience
  69. Research progress on cancer-related epigenetic switches
    Chunyu Yu, Jie Sun, Jinlong Tong, Ziqing Xu, Qijia Zhang · 2025 · Investigational New Drugs
  70. Differentiation of human induced pluripotent stem cells in William's E initiation medium supplemented with 3-bromopyruvate and 2-deoxy-d-glucose
    M. Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige · 2017 · Molecular Medicine Reports
  71. Genetic and Epigenetic Modification of Rat Liver Progenitor Cells via HNF4α Transduction and 5’ Azacytidine Treatment: An Integrated miRNA and mRNA Expression Profile Analysis
    Jennifer Bolleyn, Matthias Rombaut, Nisha Nair, Steven Branson, Anja Heymans, Marinee Chuah, Thierry VandenDriessche, Vera Rogiers, Joery De Kock, Tamara Vanhaecke · 2020 · Genes
  72. In Vivo Tumorigenicity of the 20q11.21 Amplicon in an Engraftment Model of hPSCs and Differentiated Liver Cells
    Chris S. Pridgeon, Shiva S. Forootan, Fang Zhang, Nicholas Harper, Daniel H. Palmer, Richard Weightman, Siân Gregory, Zoë Hewitt, Duncan Baker, Jason Alexander Halliwell et al. · 2023 · Journal of Stem Cells and Regenerative Medicine
  73. Gene set based systematic analysis of prostate cancer and its subtypes
    Senlin Ye, Haohui Wang, Kancheng He, Hongwei Shen, Mou Peng, Yeqi Nian, Rongrong Cui, Yi Lu · 2019 · Future Oncology
  74. Relationships between the expression of hepatocyte nuclear factors and factors essential for lipoprotein production in a human mesenchymal stem cell line, UE7T-13
    Akira Sasaki, Kazuyuki Hiwatashi, Masanori Kumagai, Keishi Hata, Masayuki Kobayashi · 2016 · Bioscience Biotechnology and Biochemistry
  75. Transcriptional Control: A Directional Sign at the Crossroads of Adult Hepatic Progenitor Cells' Fates
    Chenhao Xu, Xixi Fang, Yisu Song, Ze Xiang, Xiao Xu, Xuyong Wei · 2024 · International Journal of Biological Sciences
  76. Solute carrier family 2 member 2 (glucose transporter 2): a common factor of hepatocyte and hepatocellular carcinoma differentiation
    Yejin Kim, Yeuni Yu, Hye Jin Heo, Eun Sun Kim, Kyungjae Myung, Ninib Baryawno, Yun Hak Kim, Chang‐Kyu Oh · 2025 · PLoS ONE
  77. Genome-wide selection signal analysis reveals copy number variation associated with litter size in Guizhou Black goat
    Yanpin Zhao, Yong Han, Chao Yuan, Yang Yang, Yong Long, Wen Xiao · 2025 · Frontiers in Veterinary Science
  78. Generation and transplantation of hepatocytes‐like cells using human origin hepatogenic serum for acute liver injury treatment
    Santosh Gupta, Akriti Sharma, Sugan Paneerselvan, Sangeetha Kandoi, Bamadeb Patra, Dillip Kumar Bishi, Rama Shanker Verma · 2022 · Xenotransplantation
  79. Induction of Hepatocyte Differentiation in Human Pluripotent Stem Cells
    M. Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige · 2015 · Journal of Gastroenterology and Hepatology Research
  80. From Human-Induced Pluripotent Stem Cells to Liver Disease Modeling: A Focus on Dyslipidemia
    Salam Idriss, K. Zibara, B. Cariou, K. Si-Tayeb · 2015 · Current Pathobiology Reports
  81. Hepatic Progenitor Specification from Pluripotent Stem Cells using a Defined Differentiation System
    Jose Meseguer-Ripolles, Yu Wang, Agnes Sorteberg, Aishwariya Sharma, Nan-Linda Ding, Baltasar Lucendo‐Villarin, Philipp Krämer, Charis‐Patricia Segeritz, David C. Hay · 2020 · Journal of Visualized Experiments
  82. Hepatic Progenitor Specification from Pluripotent Stem Cells using a Defined Differentiation System
    Jose Meseguer-Ripolles, Yu Wang, Agnes Sorteberg, Aishwariya Sharma, Nan-Linda Ding, Baltasar Lucendo‐Villarin, Philipp Krämer, Charis‐Patricia Segeritz, David C. Hay · 2020 · Journal of Visualized Experiments
  83. 2-Deoxy-D-glucose initiates hepatocyte differentiation in human induced pluripotent stem cells
    M. Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige · 2017 · Molecular Medicine Reports
  84. Embryonic Development of the Liver
    Kenneth S. Zaret, Roque Bort, Stephen A. Duncan · 2020 · Wiley eBooks
  85. Limited oxygen availability in standard cell culture alters metabolism and function in terminally-differentiated cells
    Joycelyn Tan, Sam Virtue, Dougall M. Norris, Olivia J. Conway, Ming Hui Yang, Christopher Gribben, Fatima Lugtu, Ioannis Kamzolas, James Robert Krycer, Richard J. Mills et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  86. TBX3 advances the developmental chromatin landscape toward the hepatic fate
    Stephan, Tabea L., Cullum, Rebecca, Drissler, Sibyl, Thomas, Ashleigh, Fuglerud, Bettina M., Clement-Ranney, Makenna, Lotto, Jeremy, Krentz, Nicole A.J., Duncan, Stephen A., Hoodless, Pamela A. · 2025 · Developmental Cell
  87. Oxidative stress and GPX2 control pancreatic vs. non-pancreatic cell fate in human endoderm
    Joanna Szpotkowska, Wojciech J. Szlachcic, Katarzyna Błaszczyk, Maja Baginska, Magdalena Socha, Malgorzata Borowiak · 2026 · Nature Communications
  88. Liver Stem Cells
    Tohru Itoh, Minoru TanakaTanaka, Atsushi Miyajima · 2010 · Springer eBooks
  89. Induced Pluripotent Stem Cells as a Source of Hepatocytes
    M. Tomizawa, Fuminobu Shinozaki, Takao Sugiyama, Shigenori Yamamoto, Makoto Sueishi, Takanobu Yoshi · 2013 · InTech eBooks
  90. Le Foie
    Dominique Franco, Karim Si‐Tayeb · 2011 · Bulletin de l Académie Nationale de Médecine
  91. Regulatory transcription factors can control the process of transcription at the stage of pre-mRNA elongation
    Vasily M. Merkulov, Tatiana I. Merkulova · 2014 · Russian Journal of Genetics Applied Research
  92. A novel agonist for the HGF receptor MET promotes differentiation of human pluripotent stem cells into hepatocyte‐like cells
    Yannick Tauran, Myriam Lereau, Bertrand-David Ségard, Mathieu Danoy, Keiichi Kimura, Marie Shinohara, Arnaud Brioude, Yasuyuki Sakai, Hugo de Jonge, Oleg Melnyk et al. · 2022 · Development Growth & Differentiation
  93. Deconvolving sequence features that discriminate between overlapping regulatory annotations
    Akshay Kakumanu, Silvia Velasco, Esteban Mazzoni, Shaun Mahony · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  94. Regulation of cellular LDL uptake by PROX1 and CHD7
    Candilianne Serrano-Zayas, Matthew L. Holding, Taslima Gani Khan, Vi T. Tang, Jennifer M. Skidmore, Donna M. Martin, David Ginsburg, Brian T. Emmer · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  95. Modeling the personalized variations in liver disease due to α1-antitrypsin deficiency using induced pluripotent stem cell-derived hepatocyte-like cells
    Edgar N. Tafaleng · 2015 · D-Scholarship@Pitt (University of Pittsburgh)
  96. Liver cell types derived from pluripotent stem cells
    Sean Philip Harrison · 2014 · Research Explorer (The University of Manchester)
  97. Transcriptional and Epigenetic Dynamics Observed During Lineage Specification of Human Embryonic Stem Cells
    Casey A. Gifford · 2014 · Digital Access to Scholarship at Harvard (DASH) (Harvard University)
  98. Adhesion and modulation of mouse embryonic stem cells hepatocyte progeny on mouse placental extracellular matrix
    Patrícia Romagnolli · 2018
  99. Direct reprogramming of adult hepatocytes to generate LGR5+ endodermal progenitor
    Diana Chaker, Christophe Desterke, Nicolas Moniaux, Tony Ernault, Noufϊssa Oudrhiri, Jamila Faivre, Ali G. Turhan, Annelise Bennaceur Griscelli, Frank Griscelli · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  100. reader's response to the webcast video editorial entitled "the international code of medical ethics of the World Medical Association".
    Stephen S. Lefrak · 2005 · PubMed Central