Notch signaling: simplicity in design, versatility in function

Cites (333)

Items 201–333 of 333

1. Fbxw7-dependent Degradation of Notch Is Required for Control of “Stemness” and Neuronal-Glial Differentiation in Neural Stem Cells
   Akinobu Matsumoto, Ichiro Onoyama, Takehiko Sunabori, Ryoichiro Kageyama, Hideyuki Okano, Keiichi I. Nakayama · 2011 · Journal of Biological Chemistry
2. Hairy-Related Transcription Factors Inhibit Notch-Induced Smooth Muscle α-Actin Expression by Interfering With Notch Intracellular Domain/CBF-1 Complex Interaction With the CBF-1–Binding Site
   Yuefeng Tang, Sumithra Urs, Lucy Liaw · 2008 · Circulation Research
3. Hedgehog Signaling Regulates Sensory Cell Formation and Auditory Function in Mice and Humans
   Elizabeth Carroll Driver, Shannon Penick Pryor, Patrick Hill, Joyce Tannenbaum Turner, Ulrich Rüther, Leslie G. Biesecker, Andrew J. Griffith, Matthew W. Kelley · 2008 · Journal of Neuroscience
4. Processing of Notch and amyloid precursor protein by γ-secretase is spatially distinct
   Leonid Tarassishin, Ye Ingrid Yin, Bhramdeo Bassit, Yue‐Ming Li · 2004 · Proceedings of the National Academy of Sciences
5. ADAM10 is essential for proteolytic activation of Notch during thymocyte development
   L. Tian, X. Wu, Congwu Chi, Mei Han, Tian Xu, Yuan Zhuang · 2008 · International Immunology
6. Transforming Growth Factor-β (TGF-β1) Down-regulates Notch3 in Fibroblasts to Promote Smooth Muscle Gene Expression
   Simone Kennard, Hua Liu, Brenda Lilly · 2007 · Journal of Biological Chemistry
7. The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors
   A. Rajan, A. Tien, Claire M. Haueter, K. Schulze, Hugo J. Bellen · 2009 · Nature Cell Biology
8. Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling
   Kenji Matsuno, Mikiko Ito, Kazuya Hori, Fumiyasu Miyashita, Satoshi Suzuki, Noriyuki Kishi, Spyros Artavanis‐Tsakonas, Hideyuki Okano · 2002 · Development
9. Lethal Giant Discs, a Novel C2-Domain Protein, Restricts Notch Activation during Endocytosis
   Jennifer Childress, Melih Acar, Chunyao Tao, Georg A. Halder · 2006 · Current Biology
10. The Multiple Facets of Ubiquitination in the Regulation of Notch Signaling Pathway
    Stéphanie Le Bras, Nicolas Loyer, Roland Le Borgne · 2010 · Traffic
11. Loss of CHSY1, a Secreted FRINGE Enzyme, Causes Syndromic Brachydactyly in Humans via Increased NOTCH Signaling
    Jing Tian, Ling Ling, Mohammad Shboul, Hane Lee, Brian D. O’Connor, Barry Merriman, Stanley F. Nelson, Simon McKenzie Cool, Osama H. Ababneh, Azmy M. Al-Hadidy et al. · 2010 · The American Journal of Human Genetics
12. Pax9 and Jagged1 act downstream of Gli3 in vertebrate limb development
    Edwina McGlinn, Kelly Lammerts van Bueren, Salvatore Fiorenza, Rong Mo, Alisa M. Poh, Alistair R. R. Forrest, Marcelo B. Soares, Maria F. Bonaldo, Sean Michael Grimmond, Chi‐chung Hui et al. · 2005 · Mechanisms of Development
13. A DNA Transcription Code for Cell-Specific Gene Activation by Notch Signaling
    John W. Cave, Felix Loh, Joseph W. Surpris · 2005 · Current Biology
14. Activated Notch1 Target Genes during Embryonic Cell Differentiation Depend on the Cellular Context and Include Lineage Determinants and Inhibitors
    Franziska Meier-Stiegen, Ralf Schwanbeck, Kristina Bernoth, Simone Martini, Thomas Hieronymus, David Ruau, Martin Zenke, Ursula Just · 2010 · PLoS ONE
15. RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex
    David R. Friedmann, Jeffrey J. Wilson, Rhett A. Kovall · 2008 · Journal of Biological Chemistry
16. SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis
    Pilar Esteve, África Sandonís, Marcos Julian Cardozo, Jordi Malapeira, Carmen Ibáñez, Inmaculada Crespo, Séverine Marcos, Sara González-García, Marı́a L. Toribio, Joaquı́n Arribas et al. · 2011 · Nature Neuroscience
17. Notch1-expressing Cells Are Indispensable for Prostatic Branching Morphogenesis during Development and Re-growth Following Castration and Androgen Replacement
    Xi-De Wang, Jianyong Shou, Peter Wong · 2004 · Journal of Biological Chemistry
18. Mastermind-like 1 Is a Specific Coactivator of β-Catenin Transcription Activation and Is Essential for Colon Carcinoma Cell Survival
    Marie‐Clotilde Alves‐Guerra, Chiara Ronchini, Anthony J. Capobianco · 2007 · Cancer Research
19. Notch Signaling in Cardiac Development and Disease
    Donal MacGrogan, Meritxell Nus, José Luís de la Pompa · 2010 · Current topics in developmental biology/Current Topics in Developmental Biology
20. Hair cell fate decisions in cochlear development and regeneration
    Douglas Allen Cotanche, Christina L. Kaiser · 2010 · Hearing Research
21. Dual Roles of Notch in Regulation of Apically Restricted Mitosis and Apicobasal Polarity of Neuroepithelial Cells
    Shinya Ohata, Ryo Aoki, Shigeharu Kinoshita, Masahiro Yamaguchi, Sachiko Tsuruoka-Kinoshita, Hideomi Tanaka, Hironori Wada, Shugo Watabe, Takashi Tsuboi, Ichiro Masai et al. · 2011 · Neuron
22. Inhibition of myogenesis by Notch: Evidence for multiple pathways
    Matthew F. Buas, Shara Kabak, Tom R. Kadesch · 2008 · Journal of Cellular Physiology
23. Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-β signaling
    Youping Sun, William J. Lowther, Katsuaki Kato et al. · 2005 · Oncogene
24. Hes1 is required for pituitary growth and melanotrope specification
    Lori Therese Raetzman, Jennifer X. Cai, Sally Ann Camper · 2006 · Developmental Biology
25. The Translation Initiation Factor 3f (eIF3f) Exhibits a Deubiquitinase Activity Regulating Notch Activation
    Julien Moretti, Patricia Chastagner, Stefano Gastaldello, Sara Farrah Heuss, Annette M.G. Dirac, René Bernards, Maria Grazia Masucci, Alain Israël, Christel Brou · 2010 · PLoS Biology
26. Nrarp functions to modulate neural-crest-cell differentiation by regulating LEF1 protein stability
    Tohru Ishitani, Kunihiro Matsumoto, Ajay B. Chitnis, Motoyuki Itoh · 2005 · Nature Cell Biology
27. γ-Secretase Composed of PS1/Pen2/Aph1a Can Cleave Notch and Amyloid Precursor Protein in the Absence of Nicastrin
    Guojun Zhao, Zhenyi Liu, Ma. Xenia G. Ilagan, Raphael Kopan · 2010 · Journal of Neuroscience
28. Molecular separation of two signaling pathways for the receptor, Notch
    Maude Le Gall, Cordell De Mattei, Edward Giniger · 2007 · Developmental Biology
29. Fetal Leydig Cells: Progenitor Cell Maintenance and Differentiation
    Ivraym B. Barsoum, Humphrey Hung‐Chang Yao · 2010 · Journal of Andrology
30. Control of Notch-ligand endocytosis by ligand-receptor interaction
    Emil M. Hansson, Fredrik Lanner, Debashish Das, Anders Peter Mutvei, Ulrika Marklund, Johan Ericson, Filip A. Farnebo, Gabriele Stumm, Harald Stenmark, Emma Rachel Andersson et al. · 2010 · Journal of Cell Science
31. The Notch Target GeneHes1Regulates Cell Cycle Inhibitor Expression in the Developing Pituitary
    Pamela Monahan, Sabina Rybak, Lori Therese Raetzman · 2009 · Endocrinology
32. High levels of Notch signaling down-regulate Numb and Numblike
    Gavin Chapman, Lining Liu, Cecilia Sahlgren, Camilla Dahlqvist, Urban Lendahl · 2006 · The Journal of Cell Biology
33. Two opposing roles of RBP-J in Notch signaling.
    Kenji Tanigaki, T. Honjo · 2010 · Current Topics in Developmental Biology
34. The Notch Signaling Pathway Controls the Size of the Ocular Lens by Directly Suppressing p57Kip2 Expression
    Junling Jia, Min Lin, Lingna Zhang, Jean Philippe York, Pumin Zhang · 2007 · Molecular and Cellular Biology
35. Diagnostic Notch3 sequence analysis in CADASIL: Three new mutations in Dutch patients
    Saskia A.J. Lesnik Oberstein, Michel Dominique Ferrari, Egbert Bakker, J. van Gestel, Alexander L.J. Kneppers, Rune R. Frants, Martijn H. Breuning, J. Haan · 1999 · Neurology
36. The Notch pathway in the developing hematopoietic system
    Anna Bigas, Alexandre Robert‐Moreno, Lluı́s Espinosa · 2010 · The International Journal of Developmental Biology
37. Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes.
    Tetsuo Hayashi, Yukio Kageyama, Kazuhiro Ishizaka, Guangbin Xia, Kazunori Kihara, Hiroyuki Oshima · 2001 · Journal of Andrology
38. Alagille syndrome associated with a paracentric inversion 20p12.2p13 disrupting theJAG1 gene
    Pawe Stankiewicz, J Rujner, Christiane L�ffler · 2001 · American Journal of Medical Genetics
39. Rbpj regulates development of prosensory cells in the mammalian inner ear
    Norio Yamamoto, Weise Chang, Matthew W. Kelley · 2011 · Developmental Biology
40. SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural progenitor differentiation
    Johan Holmberg, Emil M. Hansson, Michal Malewicz, Magnus Sandberg, Thomas Perlmann, Urban Lendahl, Jonas Muhr · 2008 · Development
41. Sonic Hedgehog Induces Notch Target Gene Expression in Vascular Smooth Muscle Cells via VEGF-A
    David John Morrow, John P. Cullen, Weimin Liu · 2009 · Arteriosclerosis Thrombosis and Vascular Biology
42. Biodiversity and Noncanonical Notch Signaling
    Pascal Heitzler · 2010 · Current topics in developmental biology/Current Topics in Developmental Biology
43. The Notch Signalling Pathway in the Development of the Mouse Placenta
    Malgorzata Gasperowicz, F Otto · 2008 · Placenta
44. Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis
    Susan K. Tsivitse · 2010 · International Journal of Biological Sciences
45. γ-Secretase-Dependent Cleavage Initiates Notch Signaling from the Plasma Membrane
    Erika B. Sorensen, S. D. Conner · 2010 · Traffic
46. Two cases of maternal uniparental disomy 14 with a phenotype overlapping with the Prader-Willi phenotype
    Maran J.W. Berends, Roel Hordijk, Hans Scheffer, Jan C. Oosterwijk, Dicky J.J. Halley, N. Sorgedrager · 1999 · American Journal of Medical Genetics
47. JAG2 Induction in Hypoxic Tumor Cells Alters Notch Signaling and Enhances Endothelial Cell Tube Formation
    Alexander Pietras, Kristoffer von Stedingk, David Lindgren, Sven Påhlman, Håkan Axelson · 2011 · Molecular Cancer Research
48. Persistent Expression of Notch2 Delays Gonadotrope Differentiation
    Lori Therese Raetzman, Bayly S. Wheeler, Shelley A. Ross, Paul Q. Thomas, Sally Ann Camper · 2006 · Molecular Endocrinology
49. Role of the Notch signalling pathway in tooth morphogenesis
    Thimios A. Mitsiadis, Laure Regaudiat, Thomas Gridley · 2004 · Archives of Oral Biology
50. RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP‐J
    S. Wacker, Cristóbal Alvarado, Götz von Wichert, Uwe Knippschild, Jörg Wiedenmann, Karen Clauß, Gerd Ulrich Nienhaus, Horst Hameister, Bernd Baumann, Tilman Borggrefe et al. · 2010 · The EMBO Journal
51. Specificity of Notch pathway activation: Twist controls the transcriptional output in adult muscle progenitors
    Fred Bernard, Alena Krejčı́, Benjamin E. Housden, Boris Adryan, Sarah J. Bray · 2010 · Development
52. Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis
    Yonghua Pan, Zhenyi Liu, Jie Shen, Raphael Kopan · 2005 · Developmental Biology
53. Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms
    Lorenz Poellinger, Urban Lendahl · 2008 · Current Opinion in Genetics & Development
54. A Role of Receptor Notch in Ligand cis-Inhibition in Drosophila
    Isabelle Bécam, Ulla-Maj Fiúza, Alfonso Martínez Arias · 2010 · Current Biology
55. Influence of Dll4 via HIF-1α-VEGF Signaling on the Angiogenesis of Choroidal Neovascularization under Hypoxic Conditions
    Xiao Dong, Yusheng Wang, Guo‐Rui Dou, Huiyuan Hou, Yuanyuan Shi, Rui Zhang, Ke Ma, Lin Wu, Li-Bo Yao, Yan Cai et al. · 2011 · PLoS ONE
56. The Notch-2 Gene Is Regulated by Wnt Signaling in Cultured Colorectal Cancer Cells
    Jonas Ungerbäck, Nils Elander, John R. Grünberg, Mikael Sigvardsson, Peter Söderkvist · 2011 · PLoS ONE
57. Neuralized Promotes Basal to Apical Transcytosis of Delta in Epithelial Cells
    Najate Benhra, Françoise Vignaux, Aurore Dussert · 2010 · Molecular Biology of the Cell
58. Ligand-Independent Traffic of Notch Buffers Activated Armadillo in Drosophila
    Phil Sanders, Silvia Muñoz Descalzo, Tina Balayo, Frederik Wirtz‐Peitz, Penelope C. Hayward, Alfonso Martínez Arias · 2009 · PLoS Biology
59. Identification of 36 novel Jagged1 (JAG1) mutations in patients with Alagille syndrome
    Albrecht Röpke, Annegret Kujat, Mechthild Gräber · 2002 · Human Mutation
60. Identification of Notch target genes in uncommitted T-cell progenitors: no direct induction of a T-cell specific gene program
    Floor Weerkamp, Tiago Cunha Luis, Brigitta A. E. Naber, Esther E. L. Koster, Lucie Jeannotte, Jacques J. M. van Dongen, Frank J. T. Staal · 2006 · Leukemia
61. Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls
    Pamela Sklar, Sibylle G. Schwab, Nigel M. Williams et al. · 2001 · Nature Genetics
62. Domain-specific control of neurogenesis achieved through patterned regulation of Notch ligand expression
    Ulrika Marklund, Emil M. Hansson, Erik Sundström, Martin Hrabě de Angelis, Gerhard K. H. Przemeck, Urban Lendahl, Jonas Muhr, Johan Ericson · 2010 · Development
63. Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase
    Jung‐Soon Mo, Eun‐Jung Ann, Ji-Hye Yoon, Jane Jung, Yun‐Hee Choi, Hwa-Young Kim, Ji‐Seon Ahn, Su‐Man Kim, Mi‐Yeon Kim, Ji-Ae Hong et al. · 2010 · Journal of Cell Science
64. Ultradian Oscillations in Notch Signaling Regulate Dynamic Biological Events
    Ryoichiro Kageyama, Yasutaka Niwa, Hiromi Shimojo, Taeko Kobayashi, Toshiyuki Ohtsuka · 2010 · Current topics in developmental biology/Current Topics in Developmental Biology
65. Notch induces cyclin-D1-dependent proliferation during a specific temporal window of neural differentiation in ES cells
    Debashish Das, Fredrik Lanner, Heather Main, Emma Rachel Andersson, Olaf Bergmann, Cecilia Sahlgren, Nina Heldring, Ola Hermanson, Emil M. Hansson, Urban Lendahl · 2010 · Developmental Biology
66. Notch and cardiac outflow tract development
    Rajan Jain, Stacey Rentschler, Jonathan A. Epstein · 2010 · Annals of the New York Academy of Sciences
67. Roles of Drosophila Deltex in Notch receptor endocytic trafficking and activation
    Kenta Yamada, Takashi J. Fuwa, Tomonori Ayukawa, Tsubasa Tanaka, Akira Nakamura, Marian B. Wilkin, Martín Baron, Kenji Matsuno · 2011 · Genes to Cells
68. Differences in hydroxylation and binding of Notch and HIF-1α demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1)
    Sarah E. Wilkins, Jaana Hyvärinen, Johana Chicher, Jeffrey John Gorman, Daniel J. Peet, Rebecca L. Bilton, Peppi Koivunen · 2009 · The International Journal of Biochemistry & Cell Biology
69. Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue
    Miho Matsuda, Ajay B. Chitnis · 2008 · Development
70. Notch signaling in pancreatic endocrine cell and diabetes
    Wook Kim, Yu‐Kyong Shin, Byung-Joon Kim · 2009 · Biochemical and Biophysical Research Communications
71. Fringe: defining borders by regulating the Notch pathway
    Jane Y. Wu, Yi Rao · 1999 · Current Opinion in Neurobiology
72. γ-Secretase and the Intramembrane Proteolysis of Notch
    Ellen Jorissen, Bart De Strooper · 2010 · Current topics in developmental biology/Current Topics in Developmental Biology
73. Notch-GATA synergy promotes endoderm-specific expression of ref-1 in C. elegans
    Alexandre Neves, Kathryn A. English, James R Priess · 2007 · Development
74. Identification of novel Notch target genes in T cell leukaemia
    Nicholas Chadwick, Leo A. H. Zeef, Virginia Portillo · 2009 · Molecular Cancer
75. Failure to confirm NOTCH4 association with schizophrenia in a large population-based sample from Scotland
    Ralph E. McGinnis, Helen C Fox, Phil Yates, Lee-Ann Cameron, Michael R. Barnes, Ian C. Gray, Nigel K. Spurr, Orest Hurko, David St Clair · 2001 · Nature Genetics
76. The Notch pathway: hair graying and pigment cell homeostasis.
    Karine Schouwey, Friedrich Beermann · 2008 · PubMed
77. The first deltex null mutant indicates tissue-specific deltex-dependent Notch signaling in Drosophila
    Takashi J. Fuwa, Kazuya Hori, Takeshi Sasamura, Jenny E. Higgs, Martín Baron, Kenji Matsuno · 2006 · Molecular Genetics and Genomics
78. Jagged 1 is necessary for normal mouse lens formation
    Tien T. Le, Kevin W. Conley, Nadean L. Brown · 2009 · Developmental Biology
79. Thermodynamic and structural insights into CSL‐DNA complexes
    David R. Friedmann, Rhett A. Kovall · 2009 · Protein Science
80. Transcriptional Networks and Signaling Pathways that Govern Vertebrate Intestinal Development
    Joan K. Heath · 2010 · Current topics in developmental biology/Current Topics in Developmental Biology
81. Dll3 and Notch1 genetic interactions model axial segmental and craniofacial malformations of human birth defects
    Kathleen M. Loomes, Stacey A. Stevens, Megan L. O’Brien et al. · 2007 · Developmental Dynamics
82. Cell-autonomous integrin control of Wnt and Notch signalling during somitogenesis
    Charalampos Rallis, Sheena M. Pinchin, David Ish‐Horowicz · 2010 · Development
83. Regulation of expression of Vg and establishment of the dorsoventral compartment boundary in the wing imaginal disc by Suppressor of Hairless
    Stefan Koelzer, Thomas Klein · 2005 · Developmental Biology
84. Hes1 Is Required for Appropriate Morphogenesis and Differentiation during Mouse Thyroid Gland Development
    Aurore Carré, Latif Rachdi, Elodie Tron, Bénédicte Richard, Mireille Castanet, Martin Jean Schlumberger, Jean‐Michel Bidart, Gabor Szinnai, Michel Polak · 2011 · PLoS ONE
85. The intracellular domain of Notch ligand Delta1 induces cell growth arrest
    Vihren N. Kolev, Doreen Kacer, Radiana T. Trifonova et al. · 2005 · FEBS Letters
86. T Cells Develop Normally in the Absence of both Deltex1 and Deltex2
    Sophie M. Lehar, Michael J. Bevan · 2006 · Molecular and Cellular Biology
87. Two novel human NUMB isoforms provide a potential link between development and cancer
    Aldona A. Karaczyn, Mahmud Bani‐Yaghoub, Roger G. Tremblay, Chris J. Kubu, Rebecca A. Cowling, Tamara L. Adams, Igor A. Prudovsky, Douglas B. Spicer, Robert E. Friesel, Calvin Vary et al. · 2010 · Neural Development
88. Sanpodo: a context-dependent activator and inhibitor of Notch signaling during asymmetric divisions
    A. Burcu Babaoğlan, Kate M. O’Connor-Giles, Hemlata Mistry, Adam B. Schickedanz, Beth A. Wilson, James B. Skeath · 2009 · Development
89. Mechanisms of ligand‐mediated inhibition in Notch signaling activity in Drosophila
    Ulla-Maj Fiúza, Thomas Klein, Alfonso Martínez Arias · 2010 · Developmental Dynamics
90. Numb Independently Antagonizes Sanpodo Membrane Targeting and Notch Signaling in Drosophila Sensory Organ Precursor Cells
    Xin Tong, Diana Zitserman, Ilya G. Serebriiskii, Mark Andrake, Roland L. Dunbrack, Fabrice Roegiers · 2010 · Molecular Biology of the Cell
91. Correction: Estrogen Modulates Notch Activity
    2008 · Cancer Research
92. A cluster of autosomal recessive spondylocostal dysostosis caused by three newly identified DLL3 mutations segregating in a small village
    Luisa Bonafé, Cecilia Giunta, Markus Gassner · 2003 · Clinical Genetics
93. Notch ligand-dependent gene expression in human endometrial stromal cells
    Anatoly Mikhailik, James Mazella, Sharon X. Liang, Linda Tseng · 2009 · Biochemical and Biophysical Research Communications
94. Notch synergizes with axin to regulate the activity of armadillo in Drosophila
    Penelope C. Hayward, Tina Balayo, Alfonso Martínez Arias · 2006 · Developmental Dynamics
95. Role of the Drosophila Non-Visual ß-Arrestin Kurtz in Hedgehog Signalling
    Cristina Molnar, Ana Ruiz‐Gómez, Mercedes Martín, Susana Rojo Berciano, Federico Mayor, José Félix de Celis · 2011 · PLoS Genetics
96. Numb regulates Notch1, but not Notch3, during myogenesis
    Brian J. Beres, Rajani M. George, Eric J. Lougher · 2011 · Mechanisms of Development
97. Lunatic fringe potentiates Notch signaling in the developing brain
    Tomoaki Kato, Ayano Kawaguchi, Yoichi Kosodo, Hitoshi Niwa, Fumio Matsuzaki · 2010 · Molecular and Cellular Neuroscience
98. Drosophila Notch receptor activity suppresses Hairless function during adult external sensory organ development.
    D F Lyman, Barry Yedvobnick · 1995 · Genetics
99. Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development
    Yoshimasa Matsuda, Yoshio Wakamatsu, Jun Kohyama, Hideyuki Okano, Kimiko Fukuda, Sadao Yasugi · 2005 · Development
100. Notch3 Activation Promotes Invasive Glioma Formation in a Tissue Site-Specific Manner
     Tarran J. Pierfelice, Karisa C. Schreck, Louis T. Dang · 2011 · Cancer Research
101. 3? polymorphisms of ETS1 are associated with different clinical phenotypes in SLE
     Kathleen E. Sullivan, Lisa M. Piliero, Tushar Dharia, DANIEL W. GOLDMAN, Michelle Petri · 2000 · Human Mutation
102. Heterozygosity for Hypoxia Inducible Factor 1α Decreases the Incidence of Thymic Lymphomas in a p53 Mutant Mouse Model
     Jessica A. Bertout, Shetal Arvind Patel, Benjamin H. Fryer, Amy C. Durham, Kelly L. Covello, Kenneth P. Olive, Michael H. Goldschmidt, Marie Celeste Simon · 2009 · Cancer Research
103. Assembly of a Notch Transcriptional Activation Complex Requires Multimerization
     Rodrigo Vasquez‐Del Carpio, Fred M. Kaplan, Kelly Lynn Weaver, Jeffrey VanWye, Marie‐Clotilde Alves‐Guerra, David J. Robbins, Anthony J. Capobianco · 2011 · Molecular and Cellular Biology
104. The Intracellular Form of Notch Blocks Transforming Growth Factor β-Mediated Growth Arrest in Mv1Lu Epithelial Cells
     Prakash K. Rao, Tom R. Kadesch · 2003 · Molecular and Cellular Biology
105. A role for hairy1 in regulating chick limb bud growth
     Daniel Vasiliauskas, Ed Laufer, Claudio D. Stern · 2003 · Developmental Biology
106. Jagged1 gene mutation for abdominal coarctation of the aorta in Alagille syndrome
     Annick Raas‐Rothschild, Eyal Shteyer, Israela Lerer · 2002 · American Journal of Medical Genetics
107. Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud
     Jeffrey C. Francis, Freddy Radtke, Malcolm P. O. Logan · 2005 · Developmental Dynamics
108. Modest evidence for linkage and possible confirmation of association between NOTCH4 and schizophrenia in a large veterans affairs cooperative study sample
     Andrew D. Skol, Keith A. Young, Debby W. Tsuang et al. · 2002 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
109. Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells
     Heather Main, Kian Leong Lee, Henry He Yang, Saija M. Haapa-Paananen, Henrik Edgren, Shaobo Jin, Cecilia Sahlgren, Olli Kallioniemi, Lorenz Poellinger, Bing Lim et al. · 2009 · Experimental Cell Research
110. Drosophila neural progenitor polarity and asymmetric division
     Hongyan Wang, William N. Chia · 2005 · Biology of the Cell
111. Phosphorylation of Ser2078 Modulates the Notch2 Function in 32D Cell Differentiation
     Julia Inglés‐Esteve, Lluı́s Espinosa, Laurie A. Milner · 2001 · Journal of Biological Chemistry
112. Modulation of the ligand-independent traffic of Notch by Axin and Apc contributes to the activation of Armadillo in Drosophila
     Silvia Muñoz Descalzo, Katarzyna Tkocz, Tina Balayo, Alfonso Martínez Arias · 2011 · Development
113. Prognostic significance of NOTCH1 and FBXW7 mutations in pediatric T-ALL.
     Yücel Erbilgin, Müge Sayitoğlu, Ozden Hatirnaz, Ömer Doğru, Arzu Akçay, Gülen Tüysüz, Tiraje Tülin Celkan, Gönül Aydoğan, Zafer Şalcıoğlu, Çetin Timur et al. · 2010 · Europe PMC (PubMed Central)
114. GSK3 is a negative regulator of the transcriptional coactivator MAML1
     Mariana Saint Just Ribeiro, Magnus L. Hansson, Mikael J. Lindberg, Anita E. Popko-Ścibor, Annika E. Wallberg · 2009 · Nucleic Acids Research
115. The Lack of ADAM17 Activity during Embryonic Development Causes Hemorrhage and Impairs Vessel Formation
     Matthias Canault, Kaan Certel, Daphne Schatzberg, Denisa D. Wagner, Richard O. Hynes · 2010 · PLoS ONE
116. The role of Notch in patterning the human vertebral column
     Sally L. Dunwoodie · 2009 · Current Opinion in Genetics & Development
117. The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways
     Michael Bordonaro, Shruti Tewari, Wafa Atamna · 2011 · Experimental Cell Research
118. TAp73 isoforms antagonize Notch signalling in SH‐SY5Y neuroblastomas and in primary neurones
     Claudie Hooper, Mahvash Tavassoli, J. Paul Chapple, Dafe Uwanogho, Richard J. Goodyear, Gerry Melino, Simon Lovestone, Richard Killick · 2006 · Journal of Neurochemistry
119. Wingless modulates the ligand independent traffic of Notch through Dishevelled
     Silvia Muñoz Descalzo, Phil Sanders, Chrystelle Montagne, Ruth I. Johnson, Tina Balayo, Alfonso Martínez Arias · 2010 · Fly
120. A Role for Notch Signaling in Stromal Survival and Differentiation during Prostate Development
     Brigid Orr, O. Cathal Grace, Griet Vanpoucke · 2008 · Endocrinology
121. Aph‐1 interacts at the cell surface with proteins in the active γ‐secretase complex and membrane‐tethered Notch
     Emil M. Hansson, Kia Strömberg, Susanne Bergstedt · 2005 · Journal of Neurochemistry
122. DHPLC mutation analysis ofJagged1 (JAG1) reveals six novel mutations in Australian alagille syndrome patients
     Mandy L. Heritage, John MacMillan, Gregory Jon Anderson · 2002 · Human Mutation
123. Notch regulates numb: integration of conditional and autonomous cell fate specification
     Mark Rebeiz, Steven W. Miller, James W. Posakony · 2010 · Development
124. Prognostic Significance ofNOTCH1andFBXW7Mutations in Pediatric T-ALL
     Yücel Erbilgin, Müge Sayitoğlu, Özden Hatırnaz Ng, Ömer Doğru, Arzu Akçay, Gülen Tüysüz, Tiraje Tülin Celkan, Gönül Aydoğan, Zafer Şalcıoğlu, Çetin Timur et al. · 2010 · Disease Markers
125. A review and re‐evaluation of an association between the NOTCH4 locus and schizophrenia
     Zhenqi Wang, Jun Wei, Xuan Zhang, Yingjun Guo, Qi Xu, Shuzheng Liu, Jieping Shi, Yaqin Yu, Guizhi Ju, Yulin Li et al. · 2006 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
126. The Discovery and Role of CD147 as a Subunit of gamma-Secretase Complex
     Shuxia Zhou, Hua Zhou, Peter J. Walian · 2006 · Drug News & Perspectives
127. Pseudodominant inheritance of spondylocostal dysostosis type 1 caused by two familial delta‐like 3 mutations
     Neil Vincent Whittock, Sian Ellard, Jaine Duncan · 2004 · Clinical Genetics
128. Transforming acidic coiled-coil protein-3 (Tacc3) acts as a negative regulator of Notch signaling through binding to CDC10/Ankyrin repeats
     Sharon A. Bargo, Ahmed M. Raafat, David McCurdy, Idean Amirjazil, Youmin Shu, June L. Traicoff, Joshua Plant, Barbara K. Vonderhaar, Robert Callahan · 2010 · Biochemical and Biophysical Research Communications
129. Ligand-binding and signaling properties of the Ax[M1] form of Notch
     Lídia Pérez, Marco Milán, Sarah J. Bray, Stephen Michael Cohen · 2005 · Mechanisms of Development
130. Association of six polymorphisms of the NOTCH4 gene with schizophrenia in the Japanese population
     Mamoru Tochigi, Xuan Zhang, Tadashi Umekage et al. · 2004 · American Journal of Medical Genetics Part B Neuropsychiatric Genetics
131. Novel splicing and missense mutations in autosomal dominant polycystic kidney disease 1 (PKD1) gene: Expression of mutated genes
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132. No evidence for association between NOTCH4 and schizophrenia in a large family-based and case–control association analysis
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