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Cited by 188

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Genes involved in forebrain development in the zebrafish, Danio rerio

Heisenberg, Carl-Philipp, Brand, Michael, Jiang, Yun-Jin, Warga, Rachel M., Beuchle, Dirk, Eeden, Fredericus J. M. van, Furutani-Seiki, Makoto, Granato, Michael, Haffter, Pascal, Hammerschmidt, Matthias, Kane, Donald A., Kelsh, Robert N., Mullins, Mary C., Odenthal, Jörg, Nüsslein-Volhard, Christiane·1996·Development

Abstract

We identified four zebrafish mutants with defects in forebrain induction and patterning during embryogenesis. The four mutants define three genes: masterblind (mbl), silberblick (slb), and knollnase (kas). In mbl embryos, the anterior forebrain acquires posterior forebrain characteristics: anterior structures such as the eyes, olfactory placodes and the telencephalon are missing, whereas the epiphysis located in the posterior forebrain is expanded. In slb embryos, the extension of the embryonic axis is initially delayed and eventually followed by a partial fusion of the eyes. Finally, in kas embryos, separation of the telencephalic primordia is incomplete and dorsal midline cells fail to form a differentiated roof plate. Analysis of the mutant phenotypes indicates that we have identified genes essential for the specification of the anterior forebrain (mbl), positioning of the eyes (slb) and differentiation of the roof plate (kas). In an appendix to this study we list mutants showing alterations in the size of the eyes and abnormal differentiation of the lenses.

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Metadata

Authors
Heisenberg, C.-P., Brand, M., Jiang, Y.-J., Warga, R. M., Beuchle, D., Eeden, F. J. M. V., Furutani-Seiki, M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D. A., Kelsh, R. N., Mullins, M. C., Odenthal, J., & Nüsslein-Volhard, C.
Venue
Development
Published
1996-12-01
Volume
123
Issue
1
Pages
191-203
ISSN
  • 0950-1991 (ISSN-L)
  • 1477-9129
OpenAlex
W1751159137
Cited by
188
References
3
FWCI
5.69
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Genes involved in forebrain development in the zebrafish, Danio rerio. https://app.cochat.ai/papers/10.1242/dev.123.1.191
The paper
Heisenberg, C.-P., Brand, M., Jiang, Y.-J., Warga, R. M., Beuchle, D., Eeden, F. J. M. V., Furutani-Seiki, M., Granato, M., Haffter, P., Hammerschmidt, M., Kane, D. A., Kelsh, R. N., Mullins, M. C., Odenthal, J., & Nüsslein-Volhard, C. (1996). Genes involved in forebrain development in the zebrafish, Danio rerio. Development. https://doi.org/10.1242/dev.123.1.191

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.