The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Dental mesenchymal stem cells
Abstract
Mammalian teeth harbour mesenchymal stem cells (MSCs), which contribute to tooth growth and repair. These dental MSCs possess many in vitro features of bone marrow-derived MSCs, including clonogenicity, expression of certain markers, and following stimulation, differentiation into cells that have the characteristics of osteoblasts, chondrocytes and adipocytes. Teeth and their support tissues provide not only an easily accessible source of MSCs but also a tractable model system to study their function and properties in vivo. In addition, the accessibility of teeth together with their clinical relevance provides a valuable opportunity to test stem cell-based treatments for dental disorders. This Review outlines some recent discoveries in dental MSC function and behaviour and discusses how these and other advances are paving the way for the development of new biologically based dental therapies.
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Németh, K., Leelahavanichkul, A., Yuen, P. S. T., Mayer, B., Parmelee, A., Doi, K., Robey, P. G., Leelahavanichkul, K., Koller, B. H., Brown, J. M., et al. (2009) · Nature Medicine · doi:10.1038/nm.1905 · Cited by 2,364
Zhou, B. O., Yue, R., Murphy, M. M., Peyer, J. G., & Morrison, S. J. (2014) · Cell Stem Cell · doi:10.1016/j.stem.2014.06.008 · Cited by 1,381 · cited 1×
“Other genetic lineage-tracing experiments have identified populations of leptin receptor (LepR)- and gremlin 1-positive cells that give rise to a range of skeletal cell types in vivo (Worthley et al., 2015; Zhou et al., 2014).”
BackgroundSmith, A. J., Cassidy, N., Perry, H., Begue-Kirn, C., Ruch, J. V., & Lesot, H. (1995) · The International Journal of Developmental Biology · doi:10.1387/ijdb.7626417 · Cited by 337
Cited by
Molecular and cellular mechanisms of tooth development, homeostasis and repair
Yu, T., & Klein, O. D. (2020) · Development · doi:10.1242/dev.184754 · Cited by 267
Cellular and molecular mechanisms of tooth root development
Li, J., Parada, C., & Chai, Y. (2017) · Development · doi:10.1242/dev.137216 · Cited by 265
Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
Krivanek, J., Soldatov, R. A., Kastriti, M. E., Chontorotzea, T., Herdina, A. N., Petersen, J., Szarowska, B., Landova, M., Matejova, V. K., Holla, L. I., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-18512-7 · Cited by 265
Self-citationYang, H., Liang, Y., Cao, Y., Cao, Y., & Fan, Z. (2020) · Journal of Cellular Physiology · doi:10.1002/jcp.29687 · Cited by 30
Metadata
- Authors
- Sharpe, P. T.
- Venue
- Development
- Publisher
- The Company of Biologists
- Published
- 2016-07-01
- Volume
- 143
- Issue
- 13
- Pages
- 2273-2280
- ISSN
- 0950-1991 (ISSN-L)
- 1477-9129
- OpenAlex
- W2471224732
- Cited by
- 310
- References
- 3
- FWCI
- 15.25
- Type
- journal article
- Language
- en
- Open access
- closed
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