Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord

Delile, Julien, Rayon, Teresa, Melchionda, Manuela, Edwards, Amelia, Briscoe, James, Sagner, Andreas·2019·Development

Cited by (356)

Items 301–356 of 356

  1. Sox14 is essential for initiation of interneuron differentiation in the chick spinal cord
    Taiki Katsuyama, Minori Kadoya, Manabu Shirai, Noriaki Sasai · 2021 · Research Square
  2. Modeling Human Spine-Spinal Cord Organogenesis by hPSC-Derived Neuromesodermal Progenitors
    Dairui Li, Yuanchen Ma, Weijun Huang, Xiaoping Li, Huanyao Liu, Chuanfeng Xiong, Qi Zhao, Bin Wang, Xingqiang Lai, Shanshan Huang et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  3. A molecular atlas of adult C. elegans motor neurons reveals ancient diversity delineated by conserved transcription factor codes
    Jayson J. Smith, Seth R. Taylor, Jacob A. Blum, Aaron D. Gitler, David M. Miller, Paschalis Kratsios · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  4. Spatial transcriptomics and single-nucleus RNA sequencing reveal a transcriptomic atlas of adult human spinal cord
    Donghang Zhang, Yali Chen, Yiyong Wei, Hongjun Chen, Yujie Wu, Lin Wu, Jin Li, Qiyang Ren, Changhong Miao, Tao Zhu et al. · 2023 · eLife
  5. The contribution of de novo coding mutations to meningomyelocele
    Yoo-Jin Jiny Ha, Isaac Tang, Ashna Nisal, Ishani Jhamb, Cassidy Wallace, Sarah Schroeder, Chanjae Lee, Keng loi Vong, Naomi Meave Ojeda, Fiza Jiwani et al. · 2024 · medRxiv
  6. Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons, and heterogeneity
    Andrew E. Worthy, JoAnna T. Anderson, Alicia R. Lane, Laura J Gomez-Perez, Anthony A. Wang, Ronald W Griffith, Andre F. Rivard, Jay B. Bikoff, Francisco J. Álvarez · 2024 · eLife
  7. A single-cell atlas of spatial and temporal gene expression in the mouse cranial neural plate
    Eric Brooks, Andrew R Moorman, Bhaswati Bhattacharya, Ian S Prudhomme, Max Land, Heather L. Alcorn, Roshan Sharma, Dana Pe’er, Jennifer A. Zallen · 2025 · eLife
  8. Dual PAX3/7 transcriptional activities spatially encode spinal cell fates through distinct gene networks
    Robin Rondon, Théaud Hezez, Julien Richard Albert, Bernadette Drayton‐Libotte, Gloria González Curto, Frédéric Relaix, Claire Dugast‐Darzacq, Pascale Gilardi‐Hebenstreit, Vanessa Ribes · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  9. Tumor Microenvironment in Ovarian Cancer through Spatial Transcriptomics and Identification of Key Gene Expression Profiles
    Kevser Kübra Kırboğa, Ecir Uğur Küçüksille, Mithun Rudrapal, Emre Aktaş, Raghu Ram Achar, Gouri Deshpande, Victor Aleksandrovich Stupin, Ekaterina Vladimirovna Silina · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  10. A single cell ATAC-seq atlas uncovers dynamic changes in chromatin accessibility during cell fate specification at the neural plate border
    Eva Hamrud, Jacob Leese, Alexandre P Thiery, Ailin Leticia Buzzi, Alessandra Vigilante, James Briscoe, Andrea Streit · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  11. Dynamic Functional Pathway Development in Type 1 Spinal Interneurons: Stage-specific roles of retinoic acid activity
    Dina Rekler, Sarah A. Kagan, Noa Rachel Krutous, Susanna Ventriglia, Gilgi Friedlander, Chaya Kalcheim · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  12. Lineage origin of spinal cord cell type diversity
    Sophie Gobeil, Francisco Da Silveira Neto, Giulia Silvestrelli, Matthijs Smits, Carmen Streicher, Giselle Cheung, Simon Hippenmeyer, Lora B. Sweeney · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  13. A dynamic and spatially periodic micro-pattern of HES5 expression underlies the probability of neuronal differentiation in the mouse spinal cord
    Veronica Biga, Joshua Hawley, Emma Johns, Daniel Han, Jochen Kursawe, Paul Glendinning, Cerys S Manning, Nancy Papalopulu · 2020 · Research Explorer (The University of Manchester)
  14. Timing of neurogenesis through sequential accumulation of miR-9 due to additive expression of multiple alleles
    Ximena Soto, Joshua Burton, Cerys S Manning, Thomas George Minchington, R. Lea, J. Lee, Jochen Kursawe, Magnus Rattray, Nancy Papalopulu · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  15. Characterization of a novel Lbx1 mouse loss of function strain
    Lyvianne Decourtye, Jeremy A. McCallum-Loudeac, Sylvia Zellhuber-McMillan, Emma Young, Kathleen J. Sircombe, Megan J. Wilson · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  16. Barreras y facilitadores de la gestión del dolor posoperatorio en la enfermería iraní:: un estudio de investigación cualitativo
    Fazlollah Ahmadi · 2008 · International nursing review en español: revista oficial del Consejo Internacional de Enfermeras
  17. Regulação pré- e pós-transcricional do gene Scratch2 durante a neurogênese no tubo neural posterior.
    Carolina Purcell Goes · 2019
  18. Efeito dos fatores de transcrição NEUROD4 e SCRATCH2 no controle da proliferação, migração e transcrição em progenitores neurais embrionários.
    Shirley Mirna de La Cruz Anticona · 2021
  19. Single cell RNA-seq analysis of spinal locomotor circuitry in larval zebrafish
    Jimmy J. Kelly, Hua Wen, Paul Brehm · 2023 · eLife
  20. A spinal synergy of excitatory and inhibitory neurons coordinates ipsilateral body movements
    Marito Hayashi, Miriam Gullo, Gokhan Senturk, Stefania Di Costanzo, Shinji C. Nagasaki, Ryoichiro Kageyama, Itaru Imayoshi, Martyn Goulding, Samuel L. Pfaff, Graziana Gatto · 2023
  21. Single cell RNA-seq analysis of spinal locomotor circuitry in larval zebrafish
    Jimmy J. Kelly, Hua Wen, Paul Brehm · 2023 · eLife
  22. Regulação pré- e pós-transcricional do gene Scratch2 durante a neurogênese no tubo neural posterior.
    Carolina Purcell Goes · 2019
  23. PCL-seq: enhanced high-resolution transcriptomic profiling of region of interest in fresh frozen and FFPE tissues
    Xue Dong, Xiaonan Cui, Mengzhu Hu, Wenjian Zhou, Weiyang Shi · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  24. Homeodomain Involvement in Nuclear HOX Protein Homo- and Heterodimerization
    Damien Marchese, Laetitia Evrard, Isabelle Bergiers, Ludovic Boas, Justine Duphénieux, Maryse Hermant, Tamara Pringels, Fisnik Zeqiri, Marc Pirson, Jean‐Claude Twizere et al. · 2025 · International Journal of Molecular Sciences
  25. Oscillatory Co-expression of HES1 and HES5 Enables a Hybrid State in a Bistable Transcription Factor Regulatory Motif
    Veronica Biga, Anzy Miller, Anoushka Kamath, Ying Q P Mak, Antony D. Adamson, Elli Marinopoulou, Paul François, Nancy Papalopulu, Cerys S Manning · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  26. Evidence for chronological diversification of spinal neuron subtypes by a shared sequence of transcription factors
    Laia Caudet-Segarra, Kevin T. Sangster, Julia Sagner, Artur Kania, Andreas Sagner · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  27. Spatial joint profiling of DNA methylome and transcriptome in mammalian tissues
    Chin Nien Lee, Hongxiang Fu, Angelysia Cardilla, Wanding Zhou, Yanxiang Deng · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  28. A modular enhancer mediates SCRT2 repression of ISLET1 in the spinal cord
    Vitória Samartin Botezelli, Tatiane Yumi Nakamura Kanno, Ee Shan Liau, Carolina Purcell Goes, Shirley Mirna de La Cruz Anticona, Ana Paula Azambujá, Marcos Simões-Costa, Chao Yun Irene Yan · 2025 · Developmental Biology
  29. The neuronal fate determinants SOX4/11 control mitotic fidelity of adult hippocampal precursor cells
    Sneha Adhikarla, Iris Schäffner, Angelica Luna Leal, Shailendra Kumar Singh, Benjamin Martin Häberle, Sören Turan, Elisabeth Sock, Andreas Sagner, Dieter Chichung Lie · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  30. Diverse Transcriptional Alterations in V2a Propriospinal Neurons Following Spinal Cord Injury
    Christina Thapa, Ian Thomas Walling, Praneet Chaturvedi, Sarah Baumgartner, Matthew Fleming, Jacek Biesiada, Nathan Salomonis, Steven A. Crone · 2025 · Journal of Neuroscience
  31. A dual genetic constraint underlies the conservation of early brains in vertebrates
    Rodrigo Senovilla-Ganzo, Christina Bekiari, Eneritz Rueda-Alaña, Tetsuya Yamada, Bastienne Zaremba, Ana María Aransay, Laura Escobar, Mats F. Nilsson, Marco Grillo, Henrik Kaessmann et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Stem cell-based approach to identify regulatory TFs during mammalian cell differentiation
    Yingzhen Pei, Siyi Li, Görkem Garipler, Kenji Kamimoto, Esteban O. Mazzoni · 2025 · Stem Cell Reports
  33. Temporal control of axonal floor plate crossing through a combination of incoherent feedforward and feedback loops of gene regulatory network regulating Robo3 expression
    Reut Sudakevitz-Merzbach, Madhuri Majumder, Gerard Elberg, Marah Bakhtan, Dina Rekler, Sophie Khazanov, Benjamin Joel Wheaton, Nissim Ben‐Arie, Gilgi Friedlander, Chaya Kalcheim et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  34. Capturing gene–cell duality in a cat’s cradle
    Anna Laddach, Fränze Progatzky, Vassilis Pachnis, Michael Shapiro · 2026 · Bioinformatics
  35. Independent control of neurogenesis and dorsoventral patterning by NKX2-2
    Sumin Jang, Elena V Abarinov, Julie A. Dobkin, Erica C. Hurley, Michael Closser, Lori Sussel, H. Wichterle · 2026 · Genes & Development
  36. Single-cell differential abundance detection: A new angle on dissecting tumor heterogeneity
    Ying-Xue Xiao, Jing Sun, Lingling Xie, Yue Zou, Tong Li, Youjin Hao, Bo Li · 2026 · World Journal of Clinical Oncology
  37. Entropy Sorting Feature Selection: information-theoretic gene set identification improves single-cell RNA sequencing data interpretability
    Arthur Radley, Giulia L. M. Boezio, Cameron Shand, Rubén Perez‐Carrasco, James Briscoe · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  38. The Regenerative Stage‐Defined Neurogenic Properties in the Spinal Cord of Xenopus laevis : Correlation Between Neurogenic Potential and Functional Repair of the Spinal Cord
    Ryohei Seki, Yousuke Nakano, Shinichi Hayashi, Hikaru Iwashita, Hitoshi Yokoyama, Taro Koike, Yuki Sato, Souichi Oe, Yukie Hirahara, Haruki Ochi et al. · 2026 · The Journal of Comparative Neurology
  39. Development of the spinocerebellar system within the precerebellar network
    Helen C. Lai · 2026 · Current topics in developmental biology/Current Topics in Developmental Biology
  40. Comparative analyses of regional and temporal transcriptomics of early human and mouse central nervous systems
    Zhe Wei, Xiaojie Zhou, Boyu Li, Junjie Gu, Laixiang Ge, Fan Tang, Mingyan Lin, Ying Jin · 2026 · iScience
  41. Distinct signaling center and progenitor identity dynamics initiate human forebrain patterning
    Afnan Azizi, Dana Fakhreddine, Fursham Hamid, Zeno Messi, Stephanie Strohbuecker, François Guillemot, Corinne Houart · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  42. Molecular mechanisms orchestrating commissural axon guidance
    Sergi Roig‐Puiggros · 2019
  43. Fonction d'un régulateur du cycle cellulaire, la phosphatase CDC25B, au cours de la neurogenèse chez les Mammifères
    Mélanie Roussat · 2020
  44. Douleurs chroniques : implication et potentiel thérapeutique des membres de la famille FXYD
    Alexandre Derré · 2022
  45. Étude des bases moléculaires et cellulaires de la vulnérabilité des neurones moteurs dans l'amyotrophie spinale distale des membres inférieurs
    Maëliss Calon · 2024
  46. Deciphering the nature and mode of action of the mechanisms involved in temporal patterning in Drosophila wing disc epithelial progenitors
    Fanny Chazal · 2023
  47. Maturation of spinal motor control through developmental changes in ion currents
    Stephanie F. Gaudreau, Tuan Vu Bui · 2026 · The Journal of Physiology
  48. Developing mouse inhibitory neuron single-cell transcriptomes reveal distinct modes of cell-type diversification
    Minhui Liu, Facundo Ferrero Restelli, Elia Micoli, Giulia Barbiera, Rani Moors, Evelien Nouboers, Malou Reverendo, Jessica X Du, Hannah Bertels, Dimitris Konstantopoulos et al. · 2026 · Nature Neuroscience
  49. Molecular address codes delineate circuit-specific motor neuron-muscle matchmaking in the developing tetrapod limb
    Fabio Sacher, Bianka Berki, Maëva Luxey, Antoine Fages, Patrick Tschopp · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  50. Transcriptomic analysis of spinal V1 interneurons informs their multifunctional role in motor output
    Alexandra J. Trevisan, Katie Han, Phillip Chapman, Anand S. Kulkarni, Jennifer M. Hinton, Ines Klein, Cody Ramirez, Alfonso Lavado, Graziana Gatto, Mariano I. Gabitto et al. · 2026 · Nature Communications
  51. PTPσ mediates the integration of grafted neuronal tissueoids with host neural pathways after complete spinal cord injury
    Rui Mao, Yuan-huan Ma, Jin-Yuan Xiao, Qing-shuai Wei, Yin-Chun Zhao, Qi-xing Hu, Hou-Ge Li, Ke-jun Zhang, Laijian Wang, Huijuan Shi et al. · 2026 · Science China Life Sciences
  52. Loss of Sall3 eliminates presynaptic inhibition of sensory motor circuits and impairs adaptive motor behavior
    Jennifer L. Shadrach, Amr A. Mahrous, Róbert Pálovics, Zinnia Saha, Richard H. Roth, Atharv Panditrao, Vanessa W. Y. Kan, Mark A. Gradwell, Victoria E. Abraira, Irene Lorenzo Llorente et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  53. Single-cell mapping of homocysteine-induced perturbations in avian embryogenesis using LMO and BD rhapsody transcriptomics
    Stéphanie Maupetit‐Mehouas, Felipe Maurelia, Pouria HosseinNia, Nicolas Allègre, Yoan Renaud, Jonas Cruzel, Claire Chazaud, Charlène Guillot · 2026 · iScience
  54. Gene expression programs underlying spinal commissural neuron differentiation and axon growth across the midline
    Jane Rachel Abolafia, Hanna Hameedy, Lakshmi Prakash, Ziqi Wang, Elze Amileviciute, Srikar Dudipala, A. Jaworski · 2026 · Proceedings of the National Academy of Sciences
  55. Collapse of embryonic identities and emergence of functional diversity during motor neuron maturation
    Yijia Chen, Hsuan-Ming Chi, Aileen Tian, Courtney M Stains, Alison R. Miller, Tulsi Patel · 2026 · Cell Reports
  56. microRNAs control temporal patterning of the vertebrate nervous system
    Estelle Renaux, Laia Caudet-Segarra, Archi Shailesh Mistry, Manish Pandey, Julia Sagner, Hans‐Martin Jäck, Jürgen Wittmann, Michael Wegner, Andreas Sagner · 2026 · bioRxiv (Cold Spring Harbor Laboratory)