Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases

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Items 101–200 of 344

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2. Neuronal cholesterol metabolism increases dendritic outgrowth and synaptic markers via a concerted action of GGTase-I and Trk
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3. DHCR24 reverses Alzheimer’s disease-related pathology and cognitive impairment via increasing hippocampal cholesterol levels in 5xFAD mice
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5. Embryonic exposure to 10 μg L−1lead results in female-specific expression changes in genes associated with nervous system development and function and Alzheimer's disease in aged adult zebrafish brain
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6. Relationship between Concentrations of Lutein and StARD3 among Pediatric and Geriatric Human Brain Tissue
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7. 1H NMR-based metabolomics study on a goldfish model of Parkinson’s disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
   Zhaoguang Lu, Junsong Wang, Minghui Li, Qingwang Liu, Dandan Wei, Ming‐Hua Yang, Lingyi Kong · 2014 · Chemico-Biological Interactions
8. Targeting Cholesterol Homeostasis to Fight Hearing Loss: A New Perspective
   Brigitte Malgrange, Isabel Varela‐Nieto, Philippe de Médina, Michaël R. Paillasse · 2015 · Frontiers in Aging Neuroscience
9. Cholesterol Balance in Prion Diseases and Alzheimer’s Disease
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10. Oxysterols and the NeuroVascular Unit (NVU): A far true love with bright and dark sides
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11. Haptoglobin increases with age in rat hippocampus and modulates Apolipoprotein E mediated cholesterol trafficking in neuroblastoma cell lines
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12. Membrane lipid domains in the nervous system
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13. Olesoxime in neurodegenerative diseases: Scrutinising a promising drug candidate
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14. Examination of the FDA Warning for Statins and Cognitive Dysfunction
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15. Cocaine and HIV‐1 Tat disrupt cholesterol homeostasis in astrocytes: Implications for HIV‐associated neurocognitive disorders in cocaine user patients
    Cotto, Bianca, Natarajaseenivasan, Kalimuthusamy, Ferrero, Kimberly, Wesley, Leroy, Sayre, Matthew, Langford, Dianne · 2018 · Glia
16. Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import
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17. Role of LDL Cholesterol and Endolysosomes in Amyloidogenesis and Alzheimer’s Disease
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19. LRRK2 and Lipid Pathways: Implications for Parkinson’s Disease
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20. Possible Existence of the Hypothalamic-Pituitary-Hippocampal (HPH) Axis: A Reciprocal Relationship Between Hippocampal Specific Neuroestradiol Synthesis and Neuroblastosis in Ageing Brains with Special Reference to Menopause and Neurocognitive Disorders
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21. Anti-annexin antibodies, cholesterol levels and disability in multiple sclerosis
    Chiara Mandoj, Rosaria Renna, Domenico Plantone, Isabella Sperduti, Giovanni Cigliana, Laura Conti, Tatiana Koudriavtseva · 2015 · Neuroscience Letters
22. The ATP-binding cassette transporter-2 (ABCA2) regulates esterification of plasma membrane cholesterol by modulation of sphingolipid metabolism
    Warren Davis · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
23. Amides of non-steroidal anti-inflammatory drugs with thiomorpholine can yield hypolipidemic agents with improved anti-inflammatory activity
    Panagiotis Theodosis‐Nobelos, Malamati Kourti, Antonios M. Gavalas, Eleni A. Rekka · 2015 · Bioorganic & Medicinal Chemistry Letters
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    B. Zeng, Gang Zhao, H.L. Liu · 2020 · Neuroscience
25. Brain Cytochrome P450: Navigating Neurological Health and Metabolic Regulation
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27. 27-Hydroxycholesterol Promotes the Transfer of Astrocyte-Derived Cholesterol to Neurons in Co-cultured SH-SY5Y Cells and C6 Cells
    Yushan Wang, Xiaona Zhang, Tao Wang, Wen Liu, Lijing Wang, Ling Hao, Mengwei Ju, Rong Xiao · 2020 · Frontiers in Cell and Developmental Biology
28. Lecithin-cholesterol acyltransferase in brain: Does oxidative stress influence the 24-hydroxycholesterol esterification?
    Valeria La Marca, Bernardetta Maresca, Maria Stefania Spagnuolo, Luisa Cigliano, Fabrizio Dal Piaz, Giuseppe Di Iorio, Paolo Abrescia · 2015 · Neuroscience Research
29. Importance of Apolipoprotein A-I in Multiple Sclerosis
    Lidia A. Gardner, Michael C. Levin · 2015 · Frontiers in Pharmacology
30. Interplay of Dietary Fatty Acids and Cholesterol Impacts Brain Mitochondria and Insulin Action
    Mareike Schell, Chantal Chudoba, Antoine Leboucher, Eugenia Alfine, Tanina Flore, Katrin Ritter, Katharina Weiper, Andreas Wernitz, J Henkel, André Kleinridders · 2020 · Nutrients
31. Brain metabolism as a modulator of autophagy in neurodegeneration.
    Yun Lim, Hanchae Cho, Eun-Kyoung Kim · 2016 · Brain Research
32. Acidifying Endolysosomes Prevented Low-Density Lipoprotein-Induced Amyloidogenesis
    Hui Liang, Mahmoud L. Soliman, Nicholas H. Geiger, Nicole Miller, Zahra Afghah, Koffi L. Lakpa, Xuesong Chen, Jonathan D. Geiger · 2018 · Journal of Alzheimer s Disease
33. A systematic review and meta-analysis: The effects of probiotic supplementation on metabolic profile in patients with neurological disorders
    Omid Reza Tamtaji, Alireza Milajerdi, Željko Reiner, Zatollah Asemi, Ehsan Dadgostar, Reza Heidari‐Soureshjani, Peyman Mamsharifi, Elaheh Amirani, Hamed Mirzaei, Jamal Hallajzadeh et al. · 2020 · Complementary Therapies in Medicine
34. Vitamin E supplementation modulates the biological effects of omega-3 fatty acids in naturally aged rats
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35. Dementia Prevention in Clinical Practice
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36. Mass Spectrometry Imaging of Cholesterol
    Stephanie M. Cologna · 2019 · Advances in experimental medicine and biology
37. Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis
    Lopez, Adam M., Chuang, Jen-Chieh, Posey, Kenneth S., Turley, Stephen D. · 2017 · Brain Research
38. Mutations in Niemann Pick type C gene are risk factor for Alzheimer’s disease
    Nikola D. Kresojević, Valerija Dobričić, Marina V. Svetel, Vladimir Kostić · 2014 · Medical Hypotheses
39. The effect of electronic-cigarettes aerosol on rat brain lipid profile
    Vladimiro Cardenia, Fabio Vivarelli, Silvia Cirillo, Moreno Paolini, Donatella Canistro, María Teresa Rodríguez‐Estrada · 2018 · Biochimie
40. Lipid Extraction by α-Synuclein Generates Semi-Transmembrane Defects and Lipoprotein Nanoparticles
    Jianjun Pan, Annalisa Dalzini, Nawal K. Khadka, Chinta M. Aryal, Likai Song · 2018 · ACS Omega
41. The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain
    Felix Oestereich, Noosha Yousefpour, Ethan Yang, Jasmine Phénix, Zari Saadati Nezhad, Albert Nitu, Antonio Vázquez Cobá, Alfredo Ribeiro‐da‐Silva, Pierre Chaurand, Lisa Marie Munter · 2022 · Journal of Lipid Research
42. Simvastatin Treatment Preserves Synaptic Plasticity in AβPPswe/PS1dE9 Mice
    Charles Métais, Kathryn Brennan, Alexandra J. Mably, Michael Scott, Dominic M. Walsh, Caroline E. Herron · 2014 · Journal of Alzheimer s Disease
43. Retinal axonal degeneration in Niemann–Pick type C disease
    Joachim B. Havla, M. Moser, Clara Sztatecsny, Amelie Sophia Lotz-Havla, Esther M. Maier, Baccara Hizli, Regina Schinner, Tania Kümpfel, Michael Leo Strupp, Tatiana Brémovà-Ertl et al. · 2020 · Journal of Neurology
44. Association of Cognitive Impairment in Patients on 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Inhibitors
    Satyajeet Roy, Joshua Louis Weinstock, Allyse Sachiko Ishino, Jefferson Benites, Samantha R. Pop, Christopher Perez, Edvard Adrian Gumbs, Jennifer Ann Rosenbaum, Mary Kate Roccato, Hely Shah et al. · 2017 · Journal of Clinical Medicine Research
45. Membrane cholesterol depletion in cortical neurons highlights altered NMDA receptor functionality in a mouse model of amyotrophic lateral sclerosis
    Alessia Antonini, Silvia Caioli, Luana Saba, Giulia Vindigni, Silvia Biocca, Nadia Canu, Cristina Zona · 2017 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
46. Reduced Right Frontal Fractional Anisotropy Correlated with Early Elevated Plasma LDL Levels in Obese Young Adults
    Baohui Lou, Min Chen, Xiaojie Luo, Yongming Dai · 2014 · PLoS ONE
47. Apolipoprotein D Overexpression Protects Against Kainate-Induced Neurotoxicity in Mice
    Ouafa Najyb, Sonia Do Carmo, Azadeh Alikashani, Éric Rassart · 2016 · Molecular Neurobiology
48. Screening ToxCast™ for Chemicals That Affect Cholesterol Biosynthesis: Studies in Cell Culture and Human Induced Pluripotent Stem Cell–Derived Neuroprogenitors
    Phillip A. Wages, Piyush Joshi, Keri A. Tallman, Hye‐Young Kim, Aaron B. Bowman, Ned A. Porter · 2020 · Environmental Health Perspectives
49. Chronic exposure to environmentally relevant levels of simvastatin disrupts zebrafish brain gene signaling involved in energy metabolism
    Susana Barros, Ana Maria Coimbra, Nélson Alves, Marlene Pinheiro, José Benito Quintana, Miguel Machado Santos, Teresa Neuparth · 2020 · Journal of Toxicology and Environmental Health
50. Associations between apolipoprotein E genotypes and serum levels of glucose, cholesterol, and triglycerides in a cognitively normal aging Han Chinese population
    Zhi‐Ying Wu, Qing‐Qing Tao, Yan Chen, Zhijun Liu, Yi‐Min Sun, Ping Yang, Shen-Ji Lu, Miao Xu, Jiajun Yang, Qin‐Yun Dong · 2014 · Clinical Interventions in Aging
51. Possible anti-depressant effect of efavirenz and pro-depressive-like effect of voriconazole in specified doses in various experimental models of depression in mice
    Tejal K. Patel, Vandana B. Patel, Digvijaysinh G. Rana · 2017 · Pharmacological Reports
52. A Short‐Term Western Diet Impairs Cholesterol Homeostasis and Key Players of Beta Amyloid Metabolism in Brain of Middle Aged Rats
    Maria Stefania Spagnuolo, Valentina Pallottini, Arianna Mazzoli, Lucia Iannotta, Claudia Tonini, Barbara Morone, Marcus Ståhlman, Raffaella Crescenzo, Maria Strazzullo, Susanna Iossa et al. · 2020 · Molecular Nutrition & Food Research
53. Quinovic Acid Impedes Cholesterol Dyshomeostasis, Oxidative Stress, and Neurodegeneration in an Amyloid-β-Induced Mouse Model
    Kamran Muddasar Saeed, Shahid Ali Shah, Rahat Ullah, Sayed Ibrar Alam, Jun Sung Park, Samreen Saleem, Myeung Hoon Jo, Min Woo Kim, Jong Ryeal Hahm, Myeong Ok Kim · 2020 · Oxidative Medicine and Cellular Longevity · Retracted
54. Mevalonate Cascade and Neurodevelopmental and Neurodegenerative Diseases: Future Targets for Therapeutic Application
    Hassan Marzban, Jiming Kong, Shahram E. Mehr, Jerry P. Vriend, Jiasi Li, Teng Guan, Seung‐Hyuk Chung, Nima Mirzaei, Adel Marzban, Shahla Shojaei et al. · 2016 · Current Molecular Pharmacology
55. Abnormal Cholesterol Metabolism and Lysosomal Dysfunction Induce Age-Related Hearing Loss by Inhibiting mTORC1-TFEB-Dependent Autophagy
    Yun Yeong Lee, Jungho Ha, Young Sun Kim, Sivasubramanian Ramani, Siung Sung, Eun Sol Gil, Oak‐Sung Choo, Jeong Hun Jang, Yun‐Hoon Choung · 2023 · International Journal of Molecular Sciences
56. Cortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model
    Sean Miller, Jenna C. Glatzer, Yi-chun Hsieh, Jeffrey D. Rothstein · 2018 · Journal of Neurogenetics
57. APOE ε4 Carriers Have a Greater Propensity to Glycation and sRAGE Which Is Further Influenced by RAGE G82S Polymorphism
    Permal Deo, Varinderpal Singh Dhillon, Ann Chua, Philip Thomas, Michael Felix Fenech · 2019 · The Journals of Gerontology Series A
58. Physiological role of cholesterol in human body
    M Sonal Sekhar, Srujitha Marupuru, B Shrikar Reddy, Shilia Jacob Kurian, Mahadev Rao · 2020 · Elsevier eBooks
59. Targeting cytochrome P450 46A1 and brain cholesterol 24-hydroxylation to treat neurodegenerative diseases
    Irina A. Pikuleva · 2021 · Exploration of Neuroprotective Therapy
60. Parkinsonism in Inherited Metabolic Disorders: Key Considerations and Major Features
    Nattakarn Limphaibool, P. Iwanowski, M. Holstad, Katarzyna Perkowska · 2018 · Frontiers in Neurology
61. NPC1-dependent alterations in KV2.1–CaV1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease
    Maria Casas, Karl D. Murray, Keiko Hino, Nicholas C. Vierra, Sergi Simó, James S. Trimmer, Rose Ellen Dixon, Eamonn James Dickson · 2023 · Nature Communications
62. Huntington’s Disease: Pathogenic Mechanisms and Therapeutic Targets
    Dean J. Wright, Thibault Renoir, Laura J. Gray, Anthony John Hannan · 2017 · Advances in neurobiology
63. Endosomal-Lysosomal Cholesterol Sequestration by U18666A Differentially Regulates Amyloid Precursor Protein (APP) Metabolism in Normal and APP-Overexpressing Cells
    J. Chung, Geetika Phukan, David Vergote, A. Mohamed, Mahua Maulik, Miranda Stahn, Robert J. Andrew, Gopal Thinakaran, E Chaves, Satyabrata Kar · 2018 · Molecular and Cellular Biology
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67. Aerobic Exercise Facilitates the Nuclear Translocation of SREBP2 by Activating AKT/SEC24D to Contribute Cholesterol Homeostasis for Improving Cognition in APP/PS1 Mice
    Zelin Hu, Yang-Qi Yuan, Zhen Tong, Meiqing Liao, Shunling Yuan, Weijia Wu, Yingzhe Tang, Yirong Wang, Chenhao Tang, Wenfeng Liu · 2023 · International Journal of Molecular Sciences
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    Edy Kornelius, Hsin‐Hua Li, Chiung‐Huei Peng, Hui‐Wen Hsiao, Yi‐Sun Yang, Chien‐Ning Huang, Chih‐Li Lin · 2017 · Metabolic Brain Disease
69. Low Serum High-Density Lipoprotein Cholesterol Levels Associate with the C9orf72 Repeat Expansion in Frontotemporal Lobar Degeneration Patients
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70. PDZD8-deficient mice accumulate cholesteryl esters in the brain as a result of impaired lipophagy
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71. Nodal versus Total Axonal Strain and the Role of Cholesterol in Traumatic Brain Injury
    Feng Zhu, Domenico L. Gatti, King H. Yang · 2015 · Journal of Neurotrauma
72. Lipids as Nutraceuticals: A Shift in Paradigm
    Sandeep Kumar, Bhoomika Sharma, Priyanka Bhadwal, Prerna Sharma, Navneet Agnihotri · 2018 · Elsevier eBooks
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    Raas, Quentin, Tawbeh, Ali, Tahri-Joutey, Mounia, Gondcaille, Catherine, Keime, Céline, Kaiser, Romain, Trompier, Doriane, Nasser, Boubker, Leoni, Valerio, Bellanger, Emma et al. · 2023 · Frontiers in Molecular Neuroscience
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    Callie M. Weber, Bilal Moiz, Sophia M. Zic, Viviana Alpízar Vargas, Andrew Li, Alisa Morss Clyne · 2022 · Fluids and Barriers of the CNS
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    Alana C. Costa, Helena Passarelli Giroud Joaquim, Valeria Sutti Nunes, Daniel Shikanai Kerr, Guilherme S. Ferreira, Orestes Vicente Forlenza, Wagner F. Gattaz, Leda Leme Talib · 2017 · European Archives of Psychiatry and Clinical Neuroscience
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    Myuri T. Ruthirakuhan, Nathan Herrmann, Ana C. Andreazza, Nicolaas Paul L.G. Verhoeff, Damien Gallagher, Sandra E. Black, Alex Kiss, Krista L. Lanctôt · 2019 · Journal of Alzheimer s Disease
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    Valeria Rondelli, Alexandros G. Koutsioubas, Emanuela Di Cola, Giovanna Fragneto, Isabelle Grillo, Elena Del Favero, Laura Colombo, Laura Cantú, Paola Brocca, Mario Salmona · 2022 · International Journal of Biological Macromolecules
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    Min Wang, Osamu Uchiumi, Hideo Ogiso, Yuan Shui, Jingyu Zou, Chieko Hashizume, Makoto Taniguchi, Toshiro Okazaki, Nobuo Kato · 2016 · Behavioural Brain Research
88. Prenylation Defects and Oxidative Stress Trigger the Main Consequences of Neuroinflammation Linked to Mevalonate Pathway Deregulation
    Simona Pisanti, Erika Rimondi, Elena Pozza, Elisabetta Melloni, Enrico Zauli, Maurizio Bifulco, Rosanna Martinelli, Annalisa Marcuzzi · 2022 · International Journal of Environmental Research and Public Health
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    Yuji Kurihara, Kotone Mitsunari, Nagi Mukae, Hirotaka Shoji, Tsuyoshi Miyakawa, Michiko Shirane · 2023 · Molecular Brain
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    Jacob T. Beckley, Teresa K. Aman, Michael A. Ackley, Tatiana M. Kazdoba, Michael Lewis, Anne C. Smith, Brandon J. Farley, Jing Dai, Wayne Deats, Ethan C. Hoffmann et al. · 2023 · British Journal of Pharmacology
91. Thermal Proteome Profiling Reveals Distinct Target Selectivity for Differentially Oxidized Oxysterols
    Cecilia Rossetti, Luca Laraia · 2022 · ACS Chemical Biology
92. The formation of giant plasma membrane vesicles enable new insights into the regulation of cholesterol efflux
    Alanna Sedgwick, Mary Olivia Balmert, Crislyn D’Souza‐Schorey · 2018 · Experimental Cell Research
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    Marie L. Mather, Angelina V. Evangelou, Jennifer N. Bourne, Wendy B. Macklin, Teresa L. Wood · 2025 · Glia
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    Mini Jose, Aiswarya Sivanand, Chaitra Channakeshava · 2021 · Frontiers in Molecular Neuroscience
95. Retinal cholesterol metabolism is perturbated in response to experimental glaucoma in the rat
    Elise Léger-Charnay, Ségolène Gambert, Lucy Martine, Élisabeth Dubus, Marie‐Annick Maire, Bénédicte Buteau, Tristan Morala, Vincent Gigot, Alain Marie Bron, Lionel Brétillon et al. · 2022 · PLoS ONE
96. Ischemic conditions and β-secretase activation: The impact of membrane cholesterol enrichment as triggering factor in rat brain endothelial cells
    Anna Brambilla, Elena Lonati, Chiara Milani, Angela Maria Rizzo, Francesca Farina, Laura Botto, Massimo Masserini, Paola Palestini, Alessandra Bulbarelli · 2015 · The International Journal of Biochemistry & Cell Biology
97. Cholesterol in midlife increases the risk of Alzheimer's disease during an up to 43-year follow-up
    K.K. Rantanen, Arto Y. Strandberg, Kaisu Hannele Pitkälä, Reijo S. Tilvis, Veikko V Salomaa, Timo E. Strandberg · 2014 · European Geriatric Medicine
98. Antioxidant effect of simvastatin throught oxidative imbalance caused by lisdexamfetamine dimesylate
    Eger, Guilherme A., Ferreira, Vinícius V., Batista, Camila R., Bonde, Henrique, Lima, Daniela D. de, Wyse, Angela T.S., Cruz, Júlia N. da, Rodrigues, André F., Magro, Débora D. Dal, Cruz, José G.P. da · 2016 · Anais da Academia Brasileira de Ciências
99. New insight into the role of altered brain cholesterol metabolism in the pathogenesis of AD: A unifying cholesterol hypothesis and new therapeutic approach for AD
    Xiaobo Yang, Kai Yao, Mengqi Zhang, Wenbin Zhang, Hengbing Zu · 2025 · Brain Research Bulletin
100. Bacopa monnieri confers neuroprotection by influencing signaling pathways associated with interleukin 4, 13 and extracellular matrix organization in Alzheimer's disease: A proteomics-based perspective
     Akhina Palollathil, Mohd Altaf Najar, S Amrutha, Ravishankar Pervaje, Prashant Kumar Modi, Thottethodi Subrahmanya Keshava Prasad · 2024 · Neurochemistry International