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Cited by 395

The DOI matches its Crossref record; 161 of the 161 references it cites were found in a registry or an index.

Barriers built on claudins

Turksen, Kursad, Troy, Tammy-Claire·2004·Journal of Cell Science

Abstract

The fundamental functions of epithelia and endothelia in multicellular organisms are to separate compositionally distinct compartments and regulate the exchange of small solutes and other substances between them. Tight junctions (TJs) between adjacent cells constitute the barrier to the passage of ions and molecules through the paracellular pathway and function as a `fence' within the plasma membrane to create and maintain apical and basolateral membrane domains. How TJs achieve this is only beginning to be understood. Recently identified components of TJs include the claudins, a family of four-transmembrane-span proteins that are prime candidates for molecules that function in TJ permeability. Their identification and characterization have provided new insight into the diversity of different TJs and heterogeneity of barrier functions in different epithelia and endothelia.

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Metadata

Authors
Turksen, K., & Troy, T.-C.
Venue
Journal of Cell Science
Published
2004-05-15
Volume
117
Issue
12
Pages
2435-2447
ISSN
  • 0021-9533 (ISSN-L)
  • 1477-9137
OpenAlex
W2047866696
Cited by
395
References
161
FWCI
17.27
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Barriers built on claudins. https://app.cochat.ai/papers/10.1242/jcs.01235
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Turksen, K., & Troy, T.-C. (2004). Barriers built on claudins. Journal of Cell Science. https://doi.org/10.1242/jcs.01235

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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