The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Ena/VASP: towards resolving a pointed controversy at the barbed end
Open accessAbstract
Ena/VASP proteins are conserved regulators of actin dynamics that have important roles in several physiological processes such as morphogenesis, axon guidance, endothelial barrier function, and cancer cell invasion and metastasis. Although considerable evidence points towards an anti-capping mechanism for Ena/VASP function, some controversy remains. Here, we evaluate the evidence for and against the anti-capping hypothesis, including results from some recent structural and biochemical studies that shed new light on this issue. In addition, we describe several alternate mechanisms that Ena/VASP proteins may utilize to regulate actin dynamics in vivo, including inhibition of branching, bundling and profilin-actin recruitment.
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Cites
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Cited by
Ridley, A. J. (2011) · Cell · doi:10.1016/j.cell.2011.06.010 · Cited by 956
Phagocytosis: Receptors, signal integration, and the cytoskeleton
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Signaling Networks that Regulate Cell Migration
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Metadata
- Authors
- Bear, J. E., & Gertler, F. B.
- Venue
- Journal of Cell Science
- Publisher
- The Company of Biologists
- Published
- 2009-06-15
- Volume
- 122
- Issue
- 12
- Pages
- 1947-1953
- ISSN
- 0021-9533 (ISSN-L)
- 1477-9137
- OpenAlex
- W2047757962
- Cited by
- 275
- References
- 52
- FWCI
- 8.57
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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