α Melanocyte stimulating hormone (αmsh) stimulates normal human melanocyte growth by binding to high-affinity receptors

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

Munson, P. J., & Rodbard, D. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90515-1 · Cited by 8,494 · see citing works

Growth of cultured human epidermal cells into multiple epithelia suitable for grafting.

Green, H., Kehinde, O., & Thomas, J. M. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.11.5665 · Cited by 1,251 · see citing works

Permanent coverage of large burn wounds with autologous cultured human epithelium

Gallico, G. G. (1985) · Plastic & Reconstructive Surgery · doi:10.1097/00006534-198511000-00093 · Cited by 1,033 · see citing works

Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.

Halaban, R., Langdon, R. C., Birchall, N. M., Cuono, C. B., Baird, A., Scott, G., Moellmann, G. E., & McGuire, J. (1988) · The Journal of Cell Biology · doi:10.1083/jcb.107.4.1611 · Cited by 493 · see citing works

Skin regenerated from cultured epithelial autografts on full-thickness burn wounds from 6 days to 5 years after grafting. A light, electron microscopic and immunohistochemical study.

Compton, C. C., Gill, J. M., Bradford, D. A., Regauer, S., Gallico, G. G., & O'Connor, N. E. (1989) · PubMed · Cited by 420 · see citing works

Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes

Imokawa, G., Yada, Y., & Miyagishi, M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)35817-4 · Cited by 385 · see citing works

Effects of endothelins on signal transduction and proliferation in human melanocytes.

Yada, Y., Higuchi, K., & Imokawa, G. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)55277-7 · Cited by 270 · see citing works

Interleukins 1α and 6 and Tumor Necrosis Factor-α Are Paracrine Inhibitors of Human Melanocyte Proliferation and Melanogenesis

Swope, V. B., ABDEL‐MALEK, Z. A., Kassem, L. M., & Nordlund, J. J. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12460991 · Cited by 269 · see citing works

The keratinocyte as differentiated cell type.

Green, H. (1980) · PubMed · Cited by 264 · see citing works

Multicentre experience in the treatment of burns with autologous and allogenic cultured epithelium, fresh or preserved in a frozen state

Luca, M. D., Albanese, E., Bondanza, S., Megna, M., Ugozzoli, L. A., Molina, F., Cancedda, R., Santi, P. L., Bormioli, M., Stella, M., et al. (1989) · Burns · doi:10.1016/0305-4179(89)90007-7 · Cited by 263 · see citing works

The Keratinocyte handbook

Leigh, I. M. (1994) · Cited by 227 · see citing works

Characterization of receptors for alpha-melanocyte-stimulating hormone on human melanoma cells.

Siegrist, W., Solca, F., Stutz, S., Giuffrè, L., Carrel, S., Girard, J., & Eberlé, A. N. (1989) · PubMed · Cited by 220 · see citing works

Polarized integrin mediates human keratinocyte adhesion to basal lamina.

Luca, M. D., Tamura, R. N., Kajiji, S. M., Bondanza, S., Rossino, P., Cancedda, R., Marchisio, P. C., & Quaranta, V. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.17.6888 · Cited by 210 · see citing works

Evidence for nerve growth factor-mediated paracrine effects in human epidermis.

Yaar, M., Grossman, K., Eller, M. S., & Gilchrest, B. A. (1991) · The Journal of Cell Biology · doi:10.1083/jcb.115.3.821 · Cited by 200 · see citing works

Growth-regulated synthesis and secretion of biologically active nerve growth factor by human keratinocytes.

Marco, E. D., Marchisio, P. C., Bondanza, S., Franzi, A. T., Cancedda, R., & Luca, M. D. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)54695-0 · Cited by 172 · see citing works

Human epithelial cells induce human melanocyte growth in vitro but only skin keratinocytes regulate its proper differentiation in the absence of dermis.

Luca, M. D., D'Anna, F., Bondanza, S., Franzi, A. T., & Cancedda, R. (1988) · The Journal of Cell Biology · doi:10.1083/jcb.107.5.1919 · Cited by 157 · see citing works

Human Melanocytes as a Target Tissue for Hormones: In Vitro Studies with 1α-25, dihydroxyvitamin D3, α-melanocyte Stimulating Hormone, and Beta-estradiol

Ranson, M., Posen, S., & Mason, R. S. (1988) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12477126 · Cited by 144 · see citing works

Mammalian tyrosinase: Biosynthesis, processing, and modulation by melanocyte-stimulating hormone

Jiménez, M., Kameyama, K., Maloy, W. L., Tomita, Y., & Hearing, V. J. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.11.3830 · Cited by 136 · see citing works

Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin.

Pellegrini, G., Luca, M. D., Orecchia, G. E., Balzac, F., Cremona, O., Savoia, P., Cancedda, R., & Marchisio, P. C. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115782 · Cited by 131 · see citing works

Alpha-melanocyte-stimulating hormone regulation of tyrosinase in Cloudman S-91 mouse melanoma cell cultures.

Fuller, B. B., Lunsford, J. B., & Iman, D. S. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)61306-7 · Cited by 124 · see citing works

Human Melanocyte Growth and Differentiation: A Decade of New Data

Yaar, M., & Gilchrest, B. A. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12482985 · Cited by 120 · see citing works

Treatment of Posterior Hypospadias by the Autologous Graft of Cultured Urethral Epithelium

Romagnoli, G., Luca, M. D., Faranda, F., Bandelloni, R., Franzi, A. T., Cataliotti, F., & Cancedda, R. (1990) · New England Journal of Medicine · doi:10.1056/nejm199008233230806 · Cited by 114 · see citing works

The expression of functional MSH receptors on cultured human melanocytes

DONATIEN, P. D., Hunt, G., Pieron, C. A., Lunec, J., Ta�eb, A., & Thody, A. J. (1992) · Archives of Dermatological Research · doi:10.1007/bf00372074 · Cited by 98 · see citing works

Regulatory factors that determine growth and phenotype of normal human melanocytes*1

Herlyn, M. (1988) · Experimental Cell Research · doi:10.1016/0014-4827(88)90271-6 · Cited by 97 · see citing works

Control of Melanocyte Proliferation and Differentiation in the Mouse Epidermis

Hirobe, T. (1992) · Pigment Cell Research · doi:10.1111/j.1600-0749.1992.tb00776.x · Cited by 78 · see citing works

Coculture of human keratinocytes and melanocytes: differentiated melanocytes are physiologically organized in the basal layer of the cultured epithelium.

Luca, M. D., Franzi, A. T., D'Anna, F., Zicca, A., Albanese, E. A., Bondanza, S., & Cancedda, R. (1988) · PubMed · Cited by 76 · see citing works

Radioreceptor Assay for α;-Msh Using Mouse B16 Melanoma Cells

Siegrist, W., Oestreicher, M., Stutz, S., Girard, J., & Eberlé, A. N. (1988) · Journal of Receptor Research · doi:10.3109/10799898809048996 · Cited by 71 · see citing works

The Receptor for α-Melanotropin of Mouse and Human Melanoma Cells

Solca, F., Siegrist, W., Drożdż, R., Girard, J., & Eberlé, A. N. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71674-8 · Cited by 64 · see citing works

Growth factors and tyrosine protein kinases in normal and malignant melanocytes

Halaban, R. (1991) · Cancer and Metastasis Reviews · doi:10.1007/bf00049410 · Cited by 59 · see citing works

α-MSH causes a small rise in cAMP but has no effect on basal or ultraviolet-stimulated melanogenesis in human melanocytes

Friedmann, P. S., Wren, F. E., BUFFEY, J. A., & MacNeil, S. (1990) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1990.tb01841.x · Cited by 56 · see citing works

Alpha-Melanocyte-Stimulating Hormone Immunoreactivity in Melanoma Cells

Lunec, J., Pieron, C., Sherbet, G. V., & Thody, A. J. (2008) · Pathobiology · doi:10.1159/000163583 · Cited by 56 · see citing works

Responses of Cultured Melanocytes to Defined Growth Factors

Halaban, R. (1988) · Pigment Cell Research · doi:10.1111/j.1600-0749.1988.tb00790.x · Cited by 39 · see citing works

Effects of Oxygen Tension on the Growth and Pigmentation of Normal Human Melanocytes

Horikoshi, T., Balin, A. K., & Carter, D. M. (1990) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12474550 · Cited by 26 · see citing works

Keratinocyte-melanocyte interactions in in vitro reconstituted normal human epidermis

Luca, M. D. (1994) · IRIS UNIMORE (University of Modena and Reggio Emilia) · Cited by 10 · see citing works

Genetics of hair and skin color

Rees, J. L. (2003) · Annual Review of Genetics · doi:10.1146/annurev.genet.37.110801.143233 · Cited by 485 · see citing works

Melanocortin 1 Receptor (MC1R) Gene Variants are Associated with an Increased Risk for Cutaneous Melanoma Which is Largely Independent of Skin Type and Hair Color

Kennedy, C., ter Huurne, J., Berkhout, M., Gruis, N. A., Bastiaens, M. T., Bergman, W., Willemze, R., & Bavinck, J. N. B. (2001) · Journal of Investigative Dermatology · doi:10.1046/j.0022-202x.2001.01421.x · Cited by 406 · see citing works

Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides

Abdel-Malek, Z., Swope, V. B., Suzuki, I., Akcali, C., Harriger, M. D., Boyce, S. T., Urabe, K., & Hearing, V. J. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.5.1789 · Cited by 377 · see citing works

Mechanisms of Ultraviolet Light‐Induced Pigmentation

Gilchrest, B. A., Park, H., Eller, M. S., & Yaar, M. (1996) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1996.tb02988.x · Cited by 364 · see citing works

The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma

Valverde, P. (1996) · Human Molecular Genetics · doi:10.1093/hmg/5.10.1663 · Cited by 302 · see citing works

Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways

Dumaz, N., & Marais, R. (2005) · FEBS Journal · doi:10.1111/j.1742-4658.2005.04763.x · Cited by 294 · see citing works

DNA damage enhances melanogenesis.

Eller, M. S., Ostrom, K., & Gilchrest, B. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.3.1087 · Cited by 278 · see citing works

Melanocortin 1 Receptor: Structure, Function, and Regulation

Horrell, E. M. W., Boulanger, M. C., & D'Orazio, J. A. (2016) · Frontiers in Genetics · doi:10.3389/fgene.2016.00095 · Cited by 272 · see citing works

Melanocortin-1 Receptor Gene Variants Determine the Risk of Nonmelanoma Skin Cancer Independently of Fair Skin and Red Hair

Bastiaens, M. T., ter Huurne, J. A. C., Kielich, C. J., Gruis, N. A., Westendorp, R. G. J., Vermeer, B. J., & Bavinck, J. N. B. (2001) · The American Journal of Human Genetics · doi:10.1086/319500 · Cited by 248 · see citing works

The melanocortin-1-receptor gene is the major freckle gene

Bastiaens, M. T. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.16.1701 · Cited by 232 · see citing works

Agouti Signaling Protein Inhibits Melanogenesis and the Response of Human Melanocytes to α-Melanotropin

Suzuki, I., Tada, A., Ollmann, M. M., Barsh, G. S., Im, S., Lamoreux, M. L., Hearing, V. J., Nordlund, J. J., & ABDEL‐MALEK, Z. A. (1997) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12292572 · Cited by 183 · see citing works

Characterisation of ACTH Peptides in Human Skin and Their Activation of the Melanocortin‐1 Receptor

Wakamatsu, K., GRAHAM, A., Cook, D. J., & Thody, A. J. (1997) · Pigment Cell Research · doi:10.1111/j.1600-0749.1997.tb00688.x · Cited by 175 · see citing works

Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles

Beaumont, K. A., Shekar, S. N., Newton, R. A., James, M. R., Stow, J. L., Duffy, D. L., & Sturm, R. A. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddm177 · Cited by 171 · see citing works

Proopiomelanocortin Gene Product Regulation in Keratinocytes

Wintzen, M., Yaar, M., Burbach, J. P. H., & Gilchrest, B. A. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12345496 · Cited by 146 · see citing works

Significance of the Melanocortin 1 Receptor in Regulating Human Melanocyte Pigmentation, Proliferation, and Survival

Kadekaro, A. L., Kanto, H., Kavanagh, R. J., & ABDEL‐MALEK, Z. A. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb03200.x · Cited by 140 · see citing works

Binding of α-melanocyte-stimulating hormone to its G-protein-coupled receptor on B-lymphocytes activates the Jak/STAT pathway

Buggy, J. J. (1998) · Biochemical Journal · doi:10.1042/bj3310211 · Cited by 136 · see citing works

The Role of α-Melanocyte-Stimulating Hormone in Cutaneous Biology

Luger, T. A., Scholzen, T. E., & Grabbe, S. (1997) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1038/jidsymp.1997.17 · Cited by 132 · see citing works

Genetic Association and Cellular Function of MC1R Variant Alleles in Human Pigmentation

Sturm, R. A., Duffy, D. L., Box, N. F., Newton, R. A., SHEPHERD, A. G., CHEN, W., Marks, L. H., Leonard, J. H., & Martin, N. G. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb03199.x · Cited by 128 · see citing works

Proopiomelanocortin, Its Derived Peptides, and the Skin

Wintzen, M., & Gilchrest, B. A. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12326950 · Cited by 127 · see citing works

Nle4DPhe7α-Melanocyte-Stimulating Hormone Increases the Eumelanin:Phaeomelanin Ratio in Cultured Human Melanocytes

Hunt, G., Kyne, S., Wakamatsu, K., Ito, S., & Thody, A. J. (1995) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12613565 · Cited by 118 · see citing works

Basic fibroblast growth factor induces a transformed phenotype in normal human melanocytes

Nesbit, M., Nesbit, H. K., Bennett, J., Andl, T., Hsu, M., Dejesus, E., McBrian, M., Gupta, A. R., Eck, S. L., & Herlyn, M. (1999) · Oncogene · doi:10.1038/sj.onc.1203066 · Cited by 117 · see citing works

Does α‐MSH Have a Role in Regulating Skin Pigmentation in Humans?

Thody, A. J., & GRAHAM, A. (1998) · Pigment Cell Research · doi:10.1111/j.1600-0749.1998.tb00735.x · Cited by 116 · see citing works

The Role of Melanocortin‐1 Receptor Polymorphism in Skin Cancer Risk Phenotypes

Sturm, R. A., Duffy, D. L., Box, N. F., Chen, W., Smit, D. J., Brown, D. L., Stow, J. L., Leonard, J. H., & Martin, N. G. (2003) · Pigment Cell Research · doi:10.1034/j.1600-0749.2003.00041.x · Cited by 116 · see citing works

Cutaneous Immunomodulation and Coordination of Skin Stress Responses by α‐Melanocyte‐Stimulating Hormonea

Luger, T. A., Scholzen, T. E., Brzoska, T., Becher, E., Slominski, A. T., & Paus, R. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09577.x · Cited by 108 · see citing works

The Melanocortin‐1 Receptor and Human Pigmentation

ABDEL‐MALEK, Z. A., Suzuki, I., Tada, A., Im, S., & Akçalı, K. C. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb08669.x · Cited by 106 · see citing works

α‐MSH and the Regulation of Melanocyte Function

Thody, A. J. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb08679.x · Cited by 101 · see citing works

α-Melanocyte stimulating hormone, inflammation and human melanoma

Eves, P. C., MacNeil, S., & Haycock, J. W. (2005) · Peptides · doi:10.1016/j.peptides.2005.01.027 · Cited by 99 · see citing works

Multiple Facets of the Modulation of Growth by cAMP

Roger, P. P., Reuse, S., Maenhaut, C., & Dumont, J. E. (1995) · Vitamins and hormones · doi:10.1016/s0083-6729(08)61038-9 · Cited by 92 · see citing works

Quantitative analysis of MC1R gene expression in human skin cell cultures

Roberts, D. W., Newton, R. A., Beaumont, K. A., Leonard, J. H., & Sturm, R. A. (2005) · Pigment Cell Research · doi:10.1111/j.1600-0749.2005.00286.x · Cited by 90 · see citing works

Quantitative analysis of melanin content in a three-dimensional melanoma cell culture

Chung, S., Lim, G. J., & Lee, J. Y. (2019) · Scientific Reports · doi:10.1038/s41598-018-37055-y · Cited by 87 · see citing works

Cultured Human Melanocytes Respond to MSH Peptides and ACTH

HUNT, G., DONATIEN, P. D., Lunec, J., Todd, C., KYNE, S., & Thody, A. J. (1994) · Pigment Cell Research · doi:10.1111/j.1600-0749.1994.tb00052.x · Cited by 87 · see citing works

Interactions of α-Melanotropin and Agouti on B16 Melanoma Cells: Evidence for Inverse Agonism of Agouti

Siegrist, W., Drozdz, R., Cotti, R., Willard, D. H., Wilkison, W. O., & Eberlé, A. N. (1997) · Journal of Receptors and Signal Transduction · doi:10.3109/10799899709036595 · Cited by 85 · see citing works

The neuro‐immuno‐cutaneous‐endocrine network: relationship between mind and skin

Brazzini, B., Ghersetich, I., Hercogova, J., & Lotti, T. (2003) · Dermatologic Therapy · doi:10.1046/j.1529-8019.2003.01621.x · Cited by 70 · see citing works

Modulation of melanocyte-stimulating hormone receptor expression on normal human melanocytes: evidence for a regulatory role of ultraviolet B, interleukin-1α, interleukin-1β, endothelin-1 and tumour necrosis factor-α

Funasaka, Chakraborty, Hayashi, K., Komoto, Ohashi, Nagahama, Inoue, Pawelek, & Ichihashi (1998) · British Journal of Dermatology · doi:10.1046/j.1365-2133.1998.02357.x · Cited by 81 · see citing works

Reprogramming of three-dimensional microenvironments for in vitro hair follicle induction

Kageyama, T., Shimizu, A., Anakama, R., Nakajima, R., Suzuki, K., Okubo, Y., & Fukuda, J. (2022) · Science Advances · doi:10.1126/sciadv.add4603 · Cited by 73 · see citing works

Proopiomelanocortin production by epidermal cells: evidence for an immune neuroendocrine network in the epidermis

Bhardwaj, R. S., & Luger, T. A. (1994) · Archives of Dermatological Research · doi:10.1007/bf00370724 · Cited by 69 · see citing works

Anti-inflammatory and anti-invasive effects of α-melanocyte-stimulating hormone in human melanoma cells

Eves, P. C., Haycock, J. W., Layton, C., Wagner, M., Kemp, E. H., Szabo, M., Morandini, R., Ghanem, G., García-Borrón, J. C., Jiménez‐Cervantes, C., et al. (2003) · British Journal of Cancer · doi:10.1038/sj.bjc.6601349 · Cited by 66 · see citing works

α-Melanocyte-Stimulating Hormone Modulates Nitric Oxide Production in Melanocytes1

Graham, A., Manning, P., McNeil, C. J., Szatkowski, D., Tsatmali, M., Ancāns, J., Graham, A. M., & Thody, A. J. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00879.x · Cited by 59 · see citing works

Molecular Basis of the α‐MSH/IL‐1 Antagonism

Brzoska, T., Kalden, D.-H., Scholzen, T. E., & Luger, T. A. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb08680.x · Cited by 52 · see citing works

Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing

Sun, Q., Rabbani, P. S., Takeo, M., Lee, S.-H., Lim, C. H., Noel, E.-N. S., Taketo, M. M., Myung, P. S., Millar, S. E., & Ito, M. (2018) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2018.01.030 · Cited by 49 · see citing works

Participation of the Melanocortin-1 Receptor in the UV Control of Pigmentation

Suzuki, I., Im, S., Tada, A., Barsh, G. S., Hearing, V., Scott, C., Akçalı, K. C., Davis, M. B., & ABDEL‐MALEK, Z. A. (1999) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1038/sj.jidsp.5640177 · Cited by 49 · see citing works

The role and mechanism of Asian medicinal plants in treating skin pigmentary disorders

Li, Y., Huang, J., Lu, J., Ding, Y., Jiang, L., Hu, S., Chen, J., & Zeng, Q. (2019) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2019.112173 · Cited by 44 · see citing works

Uveal Melanocytes Do Not Respond To or Express Receptors for α-Melanocyte-Stimulating Hormone

Li, L., Hu, D., Zhao, H., McCormick, S. A., Nordlund, J. J., & Boissy, R. E. (2006) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.06-0391 · Cited by 44 · see citing works

α‐MSH and Melanogenesis in Normal Human Adult Melanocytes

Hedley, S. J., Gawkrodger, D. J., Weetman, A. P., & MacNeil, S. (1998) · Pigment Cell Research · doi:10.1111/j.1600-0749.1998.tb00710.x · Cited by 42 · see citing works

Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: pigmentation marker, ultrastructural and UV-survival studies

Leonard, J. H., Marks, L. H., Chen, W., Cook, A. L., Boyle, G. M., Smit, D. J., Brown, D. L., Stow, J. L., Parsons, P. G., & Sturm, R. A. (2003) · Pigment Cell Research · doi:10.1034/j.1600-0749.2003.00033.x · Cited by 39 · see citing works

Melanocortin 1 Receptor Regulates Melanoma Cell Migration by Controlling Syndecan-2 Expression

Chung, H., Lee, J., Jeong, D., Han, I., & Oh, E. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.334730 · Cited by 39 · see citing works

MC1R and cAMP signaling inhibit cdc25B activity and delay cell cycle progression in melanoma cells

Lyons, J., Bastian, B. C., & McCormick, F. P. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1201917110 · Cited by 37 · see citing works

α‐melanocyte stimulating hormone inhibits tumour necrosis factor‐α stimulated intercellular adhesion molecule‐1 expression in normal cutaneous human melanocytes and in melanoma cell lines

Hedley, Gawkrodger, Weetman, Morandini, Boeynaems, Ghanem, & Neil, M. W. (1998) · British Journal of Dermatology · doi:10.1046/j.1365-2133.1998.02209.x · Cited by 38 · see citing works

Skin as a living coloring book: how epithelial cells create patterns of pigmentation

Weiner, L., Fu, W.-Y., Chirico, W. J., & Brissette, J. L. (2014) · Pigment Cell & Melanoma Research · doi:10.1111/pcmr.12301 · Cited by 37 · see citing works

Activation of cAMP-Dependent Protein Kinase Is Required for Optimal α-Melanocyte-Stimulating Hormone-Induced Pigmentation

Ao, Y., Park, H., Olaizola‐Horn, S., & Gilchrest, B. A. (1998) · Experimental Cell Research · doi:10.1006/excr.1998.4086 · Cited by 37 · see citing works

sAPP as a regulator of dendrite motility and melanin release in epidermal melanocytes and melanoma cells

Quast, T., Wehner, S., Kirfel, G., Jaeger, K., Luca, M. D., & Herzog, V. (2003) · The FASEB Journal · doi:10.1096/fj.02-1059fje · Cited by 37 · see citing works

α-Melanocyte-Stimulating Hormone and Endothelin-1 Have Opposing Effects on Melanocyte Adhesion, Migration, and pp125FAKPhosphorylation

Scott, G., Cassidy, L., & ABDEL‐MALEK, Z. A. (1997) · Experimental Cell Research · doi:10.1006/excr.1997.3765 · Cited by 37 · see citing works

Effect of MELANOTAN®, [Nle4, D-Phe7]-α-MSH, on melanin synthesis in humans with MC1R variant alleles

FitzGerald, L. M., Fryer, J. L., Dwyer, T., & Humphrey, S. M. (2006) · Peptides · doi:10.1016/j.peptides.2004.12.038 · Cited by 35 · see citing works

Chapter 4 The Melanocortin‐1 Receptor Gene Polymorphism and Association with Human Skin Cancer

Beaumont, K. A., Liu, Y. Y., & Sturm, R. A. (2009) · Progress in molecular biology and translational science · doi:10.1016/s1877-1173(09)88004-6 · Cited by 35 · see citing works

Pigmented human skin equivalent—as a model of the mechanisms of control of cell-cell and cell-matrix interactions

Nakazawa, K., Kalassy, M., Sahuc, F., COLLOMBEL, C., & Damour, O. (1998) · Medical & Biological Engineering & Computing · doi:10.1007/bf02518888 · Cited by 35 · see citing works

Melanocortin Signalling Mechanisms

Eves, P. C., & Haycock, J. W. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-6354-3_2 · Cited by 35 · see citing works

Nitric oxide enhances the sensitivity of alpaca melanocytes to respond to α-melanocyte-stimulating hormone by up-regulating melanocortin-1 receptor

Dong, Y., Cao, J., Wang, H., Zhang, J., Zhu, Z., Bai, R., Hao, H., He, X.-Y., Fan, R., & Dong, C. (2010) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2010.05.001 · Cited by 33 · see citing works

Melanocortins and their implication in melanoma

Siegrist, W., & Eberlé, A. N. (1995) · Trends in Endocrinology and Metabolism · doi:10.1016/1043-2760(95)00017-c · Cited by 33 · see citing works

Immunoreactive α‐Melanotropin as an Autocrine Effector in Human Melanoma Cells

Loir, B., Bouchard, B., Morandini, R., Marmol, V. D., Deraemaecker, R., García-Borrón, J. C., & Ghanem, G. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00923.x · Cited by 32 · see citing works

p53 regulates ERK 1/2/ CREB cascade via a novel SASH 1/ MAP 2K2 crosstalk to induce hyperpigmentation

Zhou, D., Kuang, Z., Zeng, X., Wang, K., Ma, J., Luo, H., Chen, M., Li, Y., Zeng, J., Li, S., et al. (2017) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.13168 · Cited by 29 · see citing works

Nitric oxide enhances melanogenesis of alpaca skin melanocytes in vitro by activating the MITF phosphorylation

Dong, Y., Wang, H., Cao, J., Ren, J., Fan, R., He, X.-Y., Smith, G. W., & Dong, C. (2011) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-011-0761-1 · Cited by 29 · see citing works

Induction of constitutive melanogenesis in amelanotic mouse melanoma cells by transfection of the human melanocortin-1 receptor gene

Chluba, J., Bagutt, C., Cotti, R., & Eberlé, A. N. (1996) · Journal of Cell Science · doi:10.1242/jcs.109.8.2023 · Cited by 29 · see citing works

Single‐nucleotide polymorphisms in pigment genes and nonmelanoma skin cancer predisposition: a systematic review

Binstock, M., Hafeez, F., Metchnikoff, C., & Arron, S. T. (2014) · British Journal of Dermatology · doi:10.1111/bjd.13283 · Cited by 28 · see citing works

Photoprotective and antioxidant effects of Rhubarb: inhibitory action on tyrosinase and tyrosine kinase activities and TNF-α, IL-1α and α-MSH production in human melanocytes

Silveira, J. P., Seito, L. N., Eberlin, S., Dieamant, G., Nogueira, C., Pereda, M. C., & Stasi, L. C. D. (2013) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-13-49 · Cited by 27 · see citing works

Melanocytes expressing MC1R polymorphisms associated with red hair color have altered MSH‐ligand activated pigmentary responses in coculture with keratinocytes

Roberts, D. W., Newton, R. A., Leonard, J. H., & Sturm, R. A. (2007) · Journal of Cellular Physiology · doi:10.1002/jcp.21318 · Cited by 24 · see citing works

The Effect of Ultraviolet B Induced Adult T Cell Leukemia‐Derived Factor/Thioredoxin (ADF/TRX) on Survival and Growth of Human Melanocytes

Funasaka, Y., & Ichihashi, M. (1997) · Pigment Cell Research · doi:10.1111/j.1600-0749.1997.tb00469.x · Cited by 23 · see citing works

The potential role of vitamin D in the progression of benign and malignant melanocytic neoplasms

Pinczewski, J., & Slominski, A. T. (2010) · Experimental Dermatology · doi:10.1111/j.1600-0625.2010.01169.x · Cited by 21 · see citing works

Structure and dynamics of ?-MSH using DRISM integral equation theory and stochastic dynamics

Prabhu, N. V., Perkyns, J. S., Pettitt, B. M., & Hruby, V. J. (1999) · Biopolymers · doi:10.1002/(sici)1097-0282(199909)50:3 · Cited by 20 · see citing works

Can the brain inhibit inflammation generated in the skin? The lesson of α‐melanocyte‐stimulating hormone

Lotti, T., Bianchi, B., Ghersetich, I., Brazzini, B., & Hercogova, J. (2002) · International Journal of Dermatology · doi:10.1111/j.1365-4632.2002.01408.x · Cited by 23 · see citing works

Neprilysin, a Novel Target for Ultraviolet B Regulation of Melanogenesis Via Melanocortins

Aberdam, É., Auberger, P., Ortonne, J. P., & Ballotti, R. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00075.x · Cited by 17 · see citing works

Human Pigmentation: Its Regulation by Ultraviolet Light and by Endocrine, Paracrine, and Autocrine Factors

ABDEL‐MALEK, Z. A., & Kadekaro, A. L. (2006) · Wiley eBooks · doi:10.1002/9780470987100.ch20 · Cited by 16 · see citing works

MSH Radiopeptides for Targeting Melanoma Metastases

Eberlé, A. N., Bapst, J.-P., Calame‐Christe, M., Tanner, H., & Froidevaux, S. (2010) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-6354-3_11 · Cited by 15 · see citing works

Dimeric DOTA-α-Melanocyte-Stimulating Hormone Analogs: Synthesis and In Vivo Characteristics of Radiopeptides with High In Vitro Activity

Bapst, J.-P., Froidevaux, S., Calame‐Christe, M., Tanner, H., & Eberlé, A. N. (2007) · Journal of Receptors and Signal Transduction · doi:10.1080/10799890701723528 · Cited by 14 · see citing works

A modified method for purifying amelanotic melanocytes from human hair follicles

Ma, H., Xue-zhuang, Y., Wang, D., Li, C., & Zhu, W. (2006) · The Journal of Dermatology · doi:10.1111/j.1346-8138.2006.00059.x · Cited by 14 · see citing works

Melanocytic Tumors

Gross, T. L., VMD, P. J. I., VMD, E. J. W., & DrMedVet, V. K. A. (2005) · doi:10.1002/9780470752487.ch34 · Cited by 14 · see citing works

Effect of UV Light on the Production of Proopiomelanocortin- Derived Peptides and Melanocortin Receptors in the Skin

Brzoska, T., Scholzen, T. E., Becher, E., & Luger, T. A. (1997) · Springer eBooks · doi:10.1007/978-3-642-60771-4_27 · Cited by 13 · see citing works

UV Exposure, Genetic Targets in Melanocytic Tumors and Transgenic Mouse Models¶

de Gruijl, F. R., van Kranen, H. J., & van Schanke, A. (2004) · Photochemistry and Photobiology · doi:10.1562/2004-09-26-ir-328.1 · Cited by 12 · see citing works

Synthesis and characterization of gold nanoparticles biosynthesised from Aspalathus linearis (Burm.f.) R.Dahlgren For progressive macular hypomelanosis

van Staden, A. B., Kovacs, D., Cardinali, G., Picardo, M., Lebeko, M., Khumalo, N. P., Ray, S. S., & Lall, N. (2021) · Journal of Herbal Medicine · doi:10.1016/j.hermed.2021.100481 · Cited by 11 · see citing works

Melanins and Melanocytes

Ortonne, J. P. (1995) · Clinical Drug Investigation · doi:10.2165/00044011-199500102-00003 · Cited by 9 · see citing works

Keratinocytes and dermal factors activate CRABP‐I in melanocytes

Sanquer, S., Reenstra, W. R., Eller, M. S., & Gilchrest, B. A. (1998) · Experimental Dermatology · doi:10.1111/j.1600-0625.1998.tb00337.x · Cited by 8 · see citing works

Red hair and pain sensitivity: insights into genomics of pain?

Williams, H., & Pandit, J. J. (2023) · Anesthesiology and Perioperative Science · doi:10.1007/s44254-023-00017-3 · Cited by 7 · see citing works

A Selective Protein Kinase C Inhibitor (CGP 41251) Positively and Negatively Modulates Melanoma Cell MSH Receptors

Siegrist, W., Sauter, P., & Eberlé, A. N. (1995) · Journal of Receptors and Signal Transduction · doi:10.3109/10799899509045221 · Cited by 6 · see citing works

Citrus‐Gene interaction and melanoma risk in the UK Biobank

Marley, A. R., Li, M., Champion, V. L., Song, Y., Han, J., & Li, X. (2021) · International Journal of Cancer · doi:10.1002/ijc.33862 · Cited by 2 · see citing works

Melanoma Development and Pigment Cell Transformation

Wellbrock, C. (2007) · Humana Press eBooks · doi:10.1007/978-1-59259-994-3_14 · Cited by 2 · see citing works

Melanocortins and Melanoma

Eberlé, A. N., Froidevaux, S., & Siegrist, W. (2000) · Humana Press eBooks · doi:10.1007/978-1-59259-031-5_17 · Cited by 2 · see citing works

Is Melanoma a Hormone-Dependent Cancer or a Hormone-Responsive Cancer?

Ramaraj, P. (2018) · IntechOpen eBooks · doi:10.5772/intechopen.76499 · Cited by 1 · see citing works

Tumor Microenvironment for Melanoma Cells

Wu, L. W., Herlyn, M., & Zhang, G. (2017) · Springer eBooks · doi:10.1007/978-3-319-41319-8_14 · Cited by 1 · see citing works

Tumor Microenvironment for Melanoma Cells

Zhang, G., & Herlyn, M. (2011) · Springer eBooks · doi:10.1007/978-3-7091-0371-5_14

Untersuchungen der Fremdstoffbindung in permanenten Keratinozyten- und Melanozyten-Zelllinien sowie die Eignung von Primärkulturen aus humanen Haarfollikeln zur In-vitro-Messung der Fremdstoffaufnahme im Haar

Magnani, D. (2006) · Carl von Ossiezky University of Oldenburg

Regulation of the Mouse and Human Melanocortin-1 Receptor

ABDEL‐MALEK, Z. A. (2000) · Humana Press eBooks · doi:10.1007/978-1-59259-031-5_18

Mathematical model of cAMP-dependent signaling pathway in constitutive and UV-induced melanogenesis

Stolnitz, M. M., & Peshkova, A. Y. (2002) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.475600

Modulação da expressão dos genes para melanopsina, clock, per1, per2 e bmal1 por melatonina em melanóforos dérmicos do anfíbio Xenopus laevis

Bluhm, A. P. C. (2008) · doi:10.11606/t.41.2008.tde-26022009-142002

Melanocytes: a new potential tool to study and monitoring Duchenne muscular dystrophy

Pellegrini, C. (2013) · AMS Dottorato Institutional Doctoral Theses Repository (University of Bologna) · doi:10.6092/unibo/amsdottorato/5149

The role of melanocortin pathways in the mesocorticolimbic system in the regulation of energy Homeostasis

Banks, K. (2015) · doi:10.25560/43937

Récepteurs cutanés à la mélanocortine de type 1 (MC1R) et réponses oxydatives aux UVA dans des kératinocytes humains HaCaT

Henri, P. (2010) · theses.fr (ABES) · doi:10.70675/3d9b68e3z3ff2z4f0czae15z1e7b3d7b9f58

Xeroderma pigmentosum : understanding pigmentation in addition to the initiation and progression of skin cancer

Kasraian, Z. (2018) · doi:10.70675/a1868dd1z7486z4a30z9abbz9078cd2b51e3

The expression of functional MSH receptors on cultured human melanocytes

DONATIEN, P. D., Hunt, G., Pieron, C. A., Lunec, J., Ta�eb, A., & Thody, A. J. (1992) · Archives of Dermatological Research · doi:10.1007/bf00372074 · Cited by 98 · see citing works

Fixation of α-Melanocyte Stimulating Hormone (α-MSH) to Human Metastatic Melanoma Cells in Vitro and in Vivo

Legros, F. J., Verhest, A. P., Coel, J., Hanson, P., Legros, S., Liteanu, A., Nuchowicz, A., Tieghem, N. V., & Lejeune, F. J. (1980) · Springer eBooks · doi:10.1007/978-94-009-8925-2_49 · Cited by 2 · see citing works

Binding of melanotropic hormones to the melanocortin receptor MC1R on human melanocytes stimulates proliferation and melanogenesis

Suzuki, I., Cone, R. D., Im, S., Nordlund, J. J., & ABDEL‐MALEK, Z. A. (1996) · Endocrinology · doi:10.1210/endo.137.5.8612494 · Cited by 332 · see citing works

a Melanocyte stimulating hormone (aMSH) stimulates normal human melanocyte growth by binding to high affinity receptors

de Luca, M., Siegrist, W., Bondanza, S., Mathor, M., Eberlé, A. N., & Cancedda, R. (1993) · CINECA IRIS Institutial Research Information System (University of Genoa)

Control of Phenotypic Expresssion of Cultured Melanoma Cells by Melanocyte Stimulating Hormones

Wong, G. L., & Pawelek, J. M. (1973) · Nature New Biology · doi:10.1038/newbio241213a0 · Cited by 156 · see citing works