Control of mitochondrial morphology by a human mitofusin
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- MFF-dependent mitochondrial fission regulates presynaptic release and axon branching by limiting axonal mitochondria sizeLewis, Tommy L., Kwon, Seok-Kyu, Lee, Annie, Shaw, Reuben, Polleux, Franck · 2018 · Nature Communications
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- Abnormalities in Mitochondrial Structure in Cells from Patients with Bipolar DisorderAnne M. Cataldo, Donna L. McPhie, Nicholas T. Lange, Steven Punzell, Sarah Elmiligy, Nancy Ye, Michael P. Froimowitz, Linda C. Hassinger, Emily B. Menesale, Laura W. Sargent et al. · 2010 · American Journal Of Pathology
- The SUMO protease SENP5 is required to maintain mitochondrial morphology and functionRodolfo Zunino, Astrid C Schauss, Peter U. Rippstein, Miguel Angel Andrade-Navarro, Heidi May McBride · 2007 · Journal of Cell Science
- Regulation of mitochondrial fusion and divisionKara L. Cerveny, Yasushi Tamura, Zhongyan Zhang, Robert E. Jensen, Hiromi Sesaki · 2007 · Trends in Cell Biology
- Mitochondrial dysfunction in inflammatory bowel diseaseElizabeth A. Novak, Kevin Patrick Mollen · 2015 · Frontiers in Cell and Developmental Biology
- Regulation of mitochondrial morphology by membrane potential, and DRP1-dependent division and FZO1-dependent fusion reaction in mammalian cellsNaotada Ishihara, Akihiro Jofuku, Yuka Eura, Katsuyoshi Mihara · 2003 · Biochemical and Biophysical Research Communications
- Dynamic actin cycling through mitochondrial subpopulations locally regulates the fission–fusion balance within mitochondrial networksAndrew S. Moore, Yvette C. Wong, Cory L. Simpson, Erika L.F. Holzbaur · 2016 · Nature Communications
- The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusionEdith D. Wong, Jennifer A. Wagner, Sidney V. Scott, Voytek Okreglak, Timothy J. Holewinske, Ann Cassidy-Stone, Jodi M. Nunnari · 2003 · The Journal of Cell Biology
- Molecular mechanisms and physiologic functions of mitochondrial dynamicsHidenori Otera, K. Mihara · 2011 · The Journal of Biochemistry
- Mitochondrial morphology in mitophagy and macroautophagyLígia C. Gomes, Luca Scorrano · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Mitochondrial GTPase mitofusin 2 mutation in Charcot?Marie?Tooth neuropathy type 2AKazuki Kijima, Chikahiko Numakura, Hiroko Izumino, Kazuo Umetsu, Atsuo Nezu, Toshihide Shiiki, Masafumi Ogawa, Yoshito Ishizaki, Takeshi Kitamura, Yasunobu Shozawa et al. · 2004 · Human Genetics
- Abnormalities of Mitochondrial Dynamics in Neurodegenerative DiseasesGao, Ju, Wang, Luwen, Liu, Jingyi, Xie, Fei, Su, Bo, Wang, Xinglong · 2017 · Antioxidants
- Structure, function, and regulation of mitofusin‐2 in health and diseaseGursimran Chandhok, Michael Lazarou, Brent Neumann · 2017 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
- Listeria monocytogenes transiently alters mitochondrial dynamics during infectionFabrizia Stavru, Frédéric Bouillaud, Anna Sartori-Rupp, Daniel Ricquier, Pascale Cossart · 2011 · Proceedings of the National Academy of Sciences
- Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1Park, Yong-Yea, Lee, Seungmin, Karbowski, Mariusz, Neutzner, Albert, Youle, Richard J., Cho, Hyeseong · 2010 · Journal of Cell Science
- Fine-Tuning of Drp1/Fis1 Availability by AKAP121/Siah2 Regulates Mitochondrial Adaptation to HypoxiaHyungsoo Kim, Maria Cecilia Scimia, Deepti Wilkinson, Ramón Dı́az-Trelles, Malcolm R. Wood, David D.L. Bowtell, Andrew G. Dillin, Mark A. Mercola, Ze’ev A. Ronai · 2011 · Molecular Cell
- High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagyLígia C. Gomes, Luca Scorrano · 2008 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
- Mitochondrial fission/fusion dynamics and apoptosisClare Sheridan, Séamus J. Martin · 2010 · Mitochondrion
- Ultrastructure of the Mitochondrion and Its Bearing on Function and BioenergeticsGiovanni Bénard, Rodrigue Rossignol · 2008 · Antioxidants and Redox Signaling
- The mitochondrial protein MTP18 contributes to mitochondrial fission in mammalian cellsDaniel Tondera, Frank Czauderna, Katharina Paulick, Rolf Schwarzer, Jörg Kaufmann, Ansgar Santel · 2005 · Journal of Cell Science
- Mitochondrial dynamics and disease, OPA1Aurélien Olichon, Emmanuelle Guillou, Cécile Delettre, Thomas Landes, Laetitia Pelloquin, Laurent Jean Emorine, Valérie Mils, Marlène Daloyau, Christian Hamel, Patrizia Amati‐Bonneau et al. · 2006 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Mitochondrial dynamics in the adult cardiomyocytes: which roles for a highly specialized cell?Jérôme Piquereau, Fanny Caffin, Marta Novotová, Christophe Lemaire, Vladimir Veksler, Anne Garnier, Renée Ventura‐Clapier, Frédéric Joubert · 2013 · Frontiers in Physiology
- The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradationKoji Yamano, Noriyuki Matsuda, Keiji Tanaka · 2016 · EMBO Reports
- Staying in Touch: The Molecular Era of Organelle Contact SitesElbaz, Yael, Schuldiner, Maya · 2011 · Trends in Biochemical Sciences
- Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural StudyPierre Cosson, Anna Marchetti, Mariella Ravazzola, Lelio Orci · 2012 · PLoS ONE
- OPA1 alternate splicing uncouples an evolutionary conserved function in mitochondrial fusion from a vertebrate restricted function in apoptosisAurélien Olichon, Ghizlane Elachouri, Laurent Baricault, Cécile Delettre, Pascale Belenguer, Guy Lenaers · 2006 · Cell Death and Differentiation
- Mitochondrial dynamics and their potential as a therapeutic targetB. N. Whitley, E.A. Engelhart, Suzanne C. Hoppins · 2019 · Mitochondrion
- mTORC1 as a Regulator of Mitochondrial Functions and a Therapeutic Target in CancerKaren Griselda de la Cruz-López, Mariel E. Toledo-Guzmán, Elizabeth Ortiz Sánchez, Alejandro García Carrancá · 2019 · Frontiers in Oncology
- A bacterial dynamin-like proteinHarry H. Low, Jan Löwe · 2006 · Nature
- Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutationYu-Chin Su, Xin Qi · 2013 · Human Molecular Genetics
- Critical dependence of neurons on mitochondrial dynamicsHsiuchen Chen, David C. Chan · 2006 · Current Opinion in Cell Biology
- Mitochondrial Dynamics in DiabetesYisang Yoon, Chad A. Galloway, Bong Sook Jhun, Tianzheng Yu · 2010 · Antioxidants and Redox Signaling
- The WD repeat protein, Mdv1p, functions as a molecular adaptor by interacting with Dnm1p and Fis1p during mitochondrial fissionQuinton Tieu, Voytek Okreglak, Kari Naylor, Jodi M. Nunnari · 2002 · The Journal of Cell Biology
- A Salmonella protein causes macrophage cell death by inducing autophagyLorraine D. Hernandez, Marc Pypaert, Richard Anthony Flavell, Jorge E. Galán · 2003 · The Journal of Cell Biology
- The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neuronsWendou Yu, Yaping Sun, Su Guo, Bingwei Lu · 2011 · Human Molecular Genetics
- A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30Wen Yue, Ziheng Chen, Hai‐Yang Liu, Yan Chen, Ming Chen, Du Feng, Chaojun Yan, Hao Wu, Lei Du, Yueying Wang et al. · 2014 · Cell Research
- Exploring the molecular interface between hypoxia-inducible factor signalling and mitochondriaLuke W. Thomas, Margaret A. Ashcroft · 2019 · Cellular and Molecular Life Sciences
- Trafficking of Heme and Porphyrins in MetazoaScott Severance, Iqbal Hamza · 2009 · Chemical Reviews
- Role of mitochondrial dynamics proteins in the pathophysiology of obesity and type 2 diabetesZorzano, Antonio, Liesa, Marc, Palacín, Manuel · 2009 · The International Journal of Biochemistry & Cell Biology
- Mitochondrial Dynamics in Cardiovascular Health and DiseaseSang‐Bing Ong, Andrew R. Hall, Derek John Hausenloy · 2012 · Antioxidants and Redox Signaling
- Mitochondrial division and fusion in metabolismMadhuparna Roy, P. Hemachandra Reddy, Miho Iijima, Hiromi Sesaki · 2015 · Current Opinion in Cell Biology
- Mitochondrial Dynamics in Stem Cells and DifferentiationBong Jong Seo, Sang Hoon Yoon, Jeong Tae · 2018 · International Journal of Molecular Sciences
- Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease?Aviva M. Tolkovsky, Luzheng Xue, Graham C. Fletcher, Vilma Borutaite · 2002 · Biochimie
- Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell deathKyriakos N. Papanicolaou, Gladys Afor Ngoh, Erinne Rose Dabkowski, Kelly A. O’Connell, Rogério Faustino Ribeiro Júnior, William C. Stanley, Kenneth X. Walsh · 2011 · American Journal of Physiology-Heart and Circulatory Physiology
- Mitofusin 2 Triggers Vascular Smooth Muscle Cell Apoptosis via Mitochondrial Death PathwayXiaomei Guo, Kuang‐Hueih Chen, Yanhong Guo, Hua Liao, Jian Tang, Rui‐Ping Xiao · 2007 · Circulation Research
- Ugo1p Links the Fzo1p and Mgm1p GTPases for Mitochondrial FusionHiromi Sesaki, Robert E. Jensen · 2004 · Journal of Biological Chemistry
- Mitophagy, Mitochondrial Dynamics, and Homeostasis in Cardiovascular AgingNe Natalie Wu, Yingmei Zhang, Jun Tao Ren · 2019 · Oxidative Medicine and Cellular Longevity
- Mitochondrial fusion proteins: Dual regulators of morphology and metabolismAntonio Zorzano A, Marc Liesa, David Sebastián, Jessica Segalés, Manuel Palacı́n · 2010 · Seminars in Cell and Developmental Biology
- Mitochondrial dynamics and viral infections: A close nexusMohsin Ahmad Khan, Gulam Hussain Syed, Seong‐Jun Kim, Aleem Siddiqui · 2015 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- OPA1 (Kjer Type) Dominant Optic Atrophy: A Novel Mitochondrial DiseaseCécile Delettre, Guy Lenaers, Laetitia Pelloquin, Pascale Belenguer, Christian Hamel · 2002 · Molecular Genetics and Metabolism
- Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarctionAndrew R. Hall, Niall Burke, Rachel K Dongworth, Siavash Beikoghli Kalkhoran, Alex Dyson, J M Vicencio, Gerald W. Dorn, Derek M. Yellon, Derek John Hausenloy · 2016 · Cell Death and Disease
- Dysregulated Mitochondrial Dynamics and Metabolism in Obesity, Diabetes, and CancerWenting Dai, Lei Jiang · 2019 · Frontiers in Endocrinology
- Mitofusin-2 Is a Major Determinant of Oxidative Stress-mediated Heart Muscle Cell ApoptosisTao Shen, Ming Zheng, Chunmei Cao, Chunlei Chen, Jian Tang, Wanrui Zhang, Heping Cheng, Kuang‐Hueih Chen, Rui‐Ping Xiao · 2007 · Journal of Biological Chemistry
- Mitochondrial fusion and division: Regulation and role in cell viabilityGiovanni Bénard, Mariusz Karbowski · 2009 · Seminars in Cell and Developmental Biology
- The ever-growing complexity of the mitochondrial fission machineryAlessandro Pagliuso, Pascale Cossart, Fabrizia Stavru · 2017 · Cellular and Molecular Life Sciences
- Loss of Mitofusin 2 Promotes Endoplasmic Reticulum StressNgoh, Gladys A., Papanicolaou, Kyriakos N., Walsh, Kenneth · 2012 · Journal of Biological Chemistry
- Clinical and electrophysiologic features of CMT2A with mutations in the mitofusin 2 geneVictoria H. Lawson, Brad V. Graham, Kevin M. Flanigan · 2005 · Neurology
- Pathomechanisms of Mutant Proteins in Charcot-Marie-Tooth DiseaseAxel Niemann, Philipp Berger, Ueli Suter · 2006 · NeuroMolecular Medicine
- Neurodegeneration as a consequence of failed mitochondrial maintenanceMariusz Karbowski, Albert Neutzner · 2011 · Acta Neuropathologica
- Mitochondrial Dynamics in MammalsHsiuchen Chen, David C. Chan · 2004 · Current topics in developmental biology/Current Topics in Developmental Biology
- Morphological dynamics of mitochondria — A special emphasis on cardiac muscle cellsJennifer Hom, Shey‐Shing Sheu · 2009 · Journal of Molecular and Cellular Cardiology
- The role of mitochondria in inherited neurodegenerative diseasesKwong, Jennifer Q., Beal, M. Flint, Manfredi, Giovanni · 2006 · Journal of Neurochemistry
- Regulation of Mitochondrial Morphology by USP30, a Deubiquitinating Enzyme Present in the Mitochondrial Outer MembraneNobuhiro Nakamura, Shigehisa Hirose · 2008 · Molecular Biology of the Cell
- Structures of human mitofusin 1 provide insight into mitochondrial tetheringYuanbo Qi, Liming Yan, Caiting Yu, Xiangyang Guo, Xin Zhou, Xiaoyu Hu, Xiaofang Huang, Zihe Rao, Zhiyong Lou, Junjie Hu · 2016 · The Journal of Cell Biology
- Emerging role of mitophagy in cardiovascular physiology and pathologyPablo Esteban Morales, Carla Arias-Durán, Yáreni Ávalos-Guajardo, Geraldine Aedo, Hugo Verdejo, Valentina Parra, Sergio Lavandero · 2019 · Molecular Aspects of Medicine
- Is Mitochondrial Dysfunction a Common Root of Noncommunicable Chronic Diseases?Alexis Díaz‐Vegas, Pablo Sánchez-Aguilera, James Robert Krycer, Pablo Esteban Morales, Matías Monsalves‐Álvarez, Mariana Cifuentes, Beverly A. Rothermel, Sergio Lavandero · 2020 · Endocrine Reviews
- Regulation of Mammalian Mitochondrial Dynamics: Opportunities and ChallengesRong Yu, Urban Lendahl, Monica Nistér, Jian Zhao · 2020 · Frontiers in Endocrinology
- Exercise-induced hormesis and skeletal muscle healthLi Li Ji, Chounghun Kang, Yong Zhang · 2016 · Free Radical Biology and Medicine
- Metabolic implications of organelle–mitochondria communicationIsabel Gordaliza‐Alaguero, Carles Cantó, Antonio Zorzano A · 2019 · EMBO Reports
- Mitochondrial fusion is required for regulation of mitochondrial DNA replicationEduardo Silva Ramos, Elisa Motori, Christian Brüser, Inge Kühl, Assa Yeroslaviz, Benedetta Ruzzenente, Johanna H.K. Kauppila, Jakob D. Busch, Kjell R. Hultenby, Bianca Hermine Habermann et al. · 2019 · PLoS Genetics
- Mitochondrial quality control: from molecule to organelleAlba Roca-Portoles, Stephen W. G. Tait · 2021 · Cellular and Molecular Life Sciences
- Axonal Transport and Mitochondrial Function in NeuronsAmrita Mandal, Catherine M. Drerup · 2019 · Frontiers in Cellular Neuroscience
- Old players in a new role: mitochondria-associated membranes, VDAC, and ryanodine receptors as contributors to calcium signal propagation from endoplasmic reticulum to the mitochondriaGyörgy Hajnóczky, György Csordás, Muqing Yi · 2002 · Cell Calcium
- The Role of Reactive Oxygen Species in the Life Cycle of the MitochondrionPaola Venditti, Sergio Di Meo · 2020 · International Journal of Molecular Sciences
- Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2Riccardo Filadi, Elisa Greotti, Gabriele Turacchio, Alberto Luini, Tullio Pozzan, Paola Pizzo · 2016 · Cell Reports
- Mitochondria and cancer: is there a morphological connection?Emilie Alirol, Jean‐Claude Martinou · 2006 · Oncogene
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- The C. elegans Opa1 Homologue EAT-3 Is Essential for Resistance to Free RadicalsTakayuki Kanazawa, Mauro Zappaterra, Ayako Hasegawa, Ashley P. Wright, Erin D Newman-Smith, KAROLYN F. BUTTLE, Kent L. McDonald, Carmen A. Mannella, Alexander M. van der Bliek · 2008 · PLoS Genetics
- Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onsetYu-Jie Li, Yu-Lu Cao, Jian-Xiong Feng, Yuanbo Qi, Shuxia Meng, Jiefeng Yang, Ya-Ting Zhong, Sisi Kang, Xiaoxue Chen, Lan Lan et al. · 2019 · Nature Communications
- Mitochondrial Dynamics: Fission and Fusion in Fate Determination of Mesenchymal Stem CellsLin Ren, Xiaodan Chen, Xiaobing Chen, Jiayan Li, Bin Cheng, Juan Xia · 2020 · Frontiers in Cell and Developmental Biology
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- Fis1 acts as a mitochondrial recruitment factor for TBC1D15 that is involved in regulation of mitochondrial morphologyKenta Onoue, Akihiro Jofuku, Reiko Ban-Ishihara, Takaya Ishihara, Maki Maeda, Takumi Koshiba, Takashi Itoh, Mitsunori Fukuda, Hidenori Otera, Toshihiko Oka et al. · 2012 · Journal of Cell Science
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- Brain region-specific altered expression and association of mitochondria-related genes in autismAyyappan Anitha, Kazuhiko Nakamura, Ismail Thanseem, Kazuo Yamada, Yoshimi Iwayama, Tomoko Toyota, Hideo Matsuzaki, Taishi Miyachi, Satoru Yamada, Masatsugu Tsujii et al. · 2012 · Molecular Autism
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- Knockdown of MTP18, a Novel Phosphatidylinositol 3-Kinase-dependent Protein, Affects Mitochondrial Morphology and Induces ApoptosisDaniel Tondera, Ansgar Santel, Rolf Schwarzer, Sybille Dames, Klaus Giese, Anke Klippel, Jörg Kaufmann · 2004 · Journal of Biological Chemistry
- A cut short to death: Parl and Opa1 in the regulation of mitochondrial morphology and apoptosisLuca Pellegrini, Luca Scorrano · 2007 · Cell Death and Differentiation
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