HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy

Beharry, Adam W., Sandesara, Pooja B., Roberts, Brandon M., Ferreira, Leonardo F., Senf, Sarah M., Judge, Andrew R.·2014·Journal of Cell Science

Cited by (128)

Items 101–128 of 128

  1. Time-dependent modulation of FoxO activity by HDAC inhibitor in oncogene-transformed E1A+Ras cells
    Alisa V. Morshneva, Olga O. Gnedina, Svetlana B. Svetlikova, Valery A. Pospelov, Maria V. Igotti · 2018 · Global Medical Genetics
  2. RNA signaling in skeletal muscle: the central role of microRNAs and exosomal microRNAs
    Shunshun Liu, Huan Dong · 2025 · Frontiers in Cell and Developmental Biology
  3. Characterization and Functional Analysis of Polyadenylation Sites in Fast and Slow Muscles
    Lulu Deng, Long Li, Cheng Zou, Chengchi Fang, Changchun Li · 2020 · BioMed Research International
  4. Oral glutamine supplementation relieves muscle loss in immobilized rats, altering p38MAPK and FOXO3a signaling pathways
    Éder Ricardo Petry, Diego de Freitas Dresch, Clarice Carvalho, Patricia Calçada Medeiros, Tatiana Gomes Rosa, Cleverson Moraes de Oliveira, Léo Anderson Meira Martins, Fátima Theresinha Costa Rodrigues Guma, Norma Possas Marroni, Clóvis Milton Duval Wannmacher · 2023 · Nutrition
  5. Therapeutic targeting of GDF11 in muscle atrophy: Insights and strategies
    Chuanzhi Wang, Xiaocao Liu, Xilong Hu, Tao Wu, Rui Duan · 2024 · International Journal of Biological Macromolecules
  6. HDAC8 regulates protein kinase D phosphorylation in skeletal myoblasts in response to stress signaling
    Justine S. Habibian, Matthew J. Bolino, Bradley S. Ferguson · 2023 · Biochemical and Biophysical Research Communications
  7. A systems approach using Diversity Outbred mice distinguishes the cardiovascular effects and genetics of circulating GDF11 from those of its homolog, myostatin
    Abigail E Starcher, Kristen B. Peissig, James B. Stanton, Gary A. Churchill, Dunpeng Cai, Joshua T. Maxwell, Arthur Grider, Kim Love, Shi‐You Chen, Amanda Erickson Coleman et al. · 2021 · G3 Genes Genomes Genetics
  8. Class I HDAC inhibitors attenuate dexamethasone-induced muscle atrophy via increased protein kinase C (PKC) delta phosphorylation
    Justine S. Habibian, Matthew J. Bolino, Anthony Qian, Rebekah J. Woolsey, David R. Quilici, Juli Petereit, Bradley S. Ferguson · 2023 · Cellular Signalling
  9. Exogenous ketone esters as a potential therapeutic for treatment of sarcopenic obesity
    Sarah E. Deemer, Brandon M. Roberts, Daniel L. Smith, Eric P. Plaisance, Andrew Philp · 2024 · American Journal of Physiology-Cell Physiology
  10. Inhibition of Histone Deacetylase 1 Prevents the Decrease in Titin (Connectin) Content and Development of Atrophy in Rat m. soleus after 3-Day Hindlimb Unloading
    Anna D. Ulanova, Yu. V. Gritsyna, A. G. Bobylev, Elmira I. Yakupova, Vitaly K. Zhalimov, Svetlana P. Belova, Ekaterina P. Mochalova, Tatiana L. Nemirovskaya, Elizabeth A. Shenkman, Ivan M. Vikhlyantsev · 2020 · Bulletin of Experimental Biology and Medicine
  11. Foxo1 nucleo-cytoplasmic distribution and unidirectional nuclear influx are the same in nuclei in a single skeletal muscle fiber but vary between fibers
    Yewei Liu, Sarah J. Russell, Martin F. Schneider · 2017 · American Journal of Physiology-Cell Physiology
  12. G9a promotes muscular atrophy in chronic aging and acute denervation
    Ying Jin, Wei Kang, Xiaolong Ji, Yihao Zhou, Ling Zheng · 2024 · Animal Diseases
  13. Muscle Disuse Atrophy
    Dongwook Yeo · 2025 · Advances in experimental medicine and biology
  14. Cancer Cachexia
    Melissa Puppa, James A. Carson · 2025 · Advances in experimental medicine and biology
  15. Epigenetic Signatures of Human Myocardium and Brown Adipose Tissue Revealed with Simultaneous Positron Emission Tomography and Magnetic Resonance of Class I Histone Deacetylases
    David Izquierdo‐Garcia, Jacob M. Hooker, Frederick A. Schroeder, Choukri Mekkaoui, Tonya M. Gilbert, Marcello Panagia, Cheryl Cero, Lindsey Rogers, Anisha Bhanot, Changning Wang et al. · 2020 · medRxiv
  16. Effects of 4-aminopyridine as an Adjuvant Therapy Following Peripheral Nerve Repair in an Animal Model of Nerve Transection Injury
    Jung Il Lee, Dong Whan Kim, Jong Woong Park, Duk Hee Lee · 2025 · Journal of Reconstructive Microsurgery
  17. Epigenetics of Cisplatin Resistance
    Steven G. Gray · 2015 · Elsevier eBooks
  18. Background and Management of Muscular Atrophy
    Julianna Cseri · 2020 · IntechOpen eBooks
  19. Modulation of the Myostatin/Follistatin Axis by Deacetylase Inhibitors: Improvement of TNFα-Induced Myotube Atrophy But Not of Experimental Cancer Cachexia
    2014 · BENTHAM SCIENCE PUBLISHERS eBooks
  20. WITHDRAWN: Relationship between the regulation of muscle atrophy and mitochondrial turnover during chronic disuse
    Liam D. Tryon, Anna Vainshtein, Jonathan Matthew Memme, Matthew J. Crilly, David Albert Hood · 2016 · Integrative Medicine Research
  21. Resistance Training Alleviates Skeletal Muscle Atrophy in Rats Exposed to Hypoxia by inhibiting Autophagy Mediated by Acetyl-FoxO1
    Pengyu Fu, KONG Zhaowei, GONG Lijing, Hans‐Christer Holmberg, Yanchun Li, Jiabei Yu, ZHU Rongxin, Jie Jia, Yang Hu · 2020
  22. The Role of Histone Deacetylases I and IIa (HDAC1, HDAC4/5) and the MAPK38 Signaling Pathway in the Regulation of Atrophic Processes under Skeletal Muscle Unloading
    Tatiana L. Nemirovskaya · 2021 · Journal of Evolutionary Biochemistry and Physiology
  23. A Combination of Formoterol and the Histone Deacetylase Inhibitor AR42 has No Effects on Muscle Mass in Tumor-Bearing Rats
    Sı́lvia Busquets, Marta Castillejo, Queralt Jové, Alina Noguera, Francisco Javier López-Soriano, Josep María Adell Argilés, Sı́lvia Busquets · 2021
  24. The Molecular Mechanisms and Treatment of Cancer-Related Cachexia
    Yongfei YOU, Yong WANG, Guohua Zhang, Yong Li · 2025 · Journal of Nutritional Science and Vitaminology
  25. Histone Acetylation/Deacetylation and Exercise: Epigenetic Mechanisms Underlying Skeletal Muscle Health and Aging
    Shuang Hao, Yumeng Hu, Lining Zhang, Jia Li · 2025 · Epigenetics and human health
  26. The role and mechanism of histone deacetylase in COPD
    Huifang Tang, Qian Gao, Xie Shu · 2026 · Molecular and Cellular Biochemistry
  27. Advances in epigenetic factors in cancer cachexia associated-muscle atrophy
    Li Li, Junaid Wazir, Fei Wang, Xiaolu Jin, Ranran Wang, Kai Lin, Zhiqiang Huang, Shiyu Song, Zhenghong Yu, Hongwei Wang · 2026 · Genes & Diseases
  28. Intramyocellular lipid droplet–mitochondria uncoupling drives muscle atrophy via metabolite-directed epigenetic reprogramming: a review
    Lingfeng Wu, Ye Wang, Kailian Ma, Yang Liu · 2026 · Frontiers in Endocrinology