HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy
Beharry, Adam W., Sandesara, Pooja B., Roberts, Brandon M., Ferreira, Leonardo F., Senf, Sarah M., Judge, Andrew R.·2014·Journal of Cell Science
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- Time-dependent modulation of FoxO activity by HDAC inhibitor in oncogene-transformed E1A+Ras cellsAlisa V. Morshneva, Olga O. Gnedina, Svetlana B. Svetlikova, Valery A. Pospelov, Maria V. Igotti · 2018 · Global Medical Genetics
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- HDAC8 regulates protein kinase D phosphorylation in skeletal myoblasts in response to stress signalingJustine S. Habibian, Matthew J. Bolino, Bradley S. Ferguson · 2023 · Biochemical and Biophysical Research Communications
- A systems approach using Diversity Outbred mice distinguishes the cardiovascular effects and genetics of circulating GDF11 from those of its homolog, myostatinAbigail E Starcher, Kristen B. Peissig, James B. Stanton, Gary A. Churchill, Dunpeng Cai, Joshua T. Maxwell, Arthur Grider, Kim Love, Shi‐You Chen, Amanda Erickson Coleman et al. · 2021 · G3 Genes Genomes Genetics
- Class I HDAC inhibitors attenuate dexamethasone-induced muscle atrophy via increased protein kinase C (PKC) delta phosphorylationJustine S. Habibian, Matthew J. Bolino, Anthony Qian, Rebekah J. Woolsey, David R. Quilici, Juli Petereit, Bradley S. Ferguson · 2023 · Cellular Signalling
- Exogenous ketone esters as a potential therapeutic for treatment of sarcopenic obesitySarah E. Deemer, Brandon M. Roberts, Daniel L. Smith, Eric P. Plaisance, Andrew Philp · 2024 · American Journal of Physiology-Cell Physiology
- Inhibition of Histone Deacetylase 1 Prevents the Decrease in Titin (Connectin) Content and Development of Atrophy in Rat m. soleus after 3-Day Hindlimb UnloadingAnna D. Ulanova, Yu. V. Gritsyna, A. G. Bobylev, Elmira I. Yakupova, Vitaly K. Zhalimov, Svetlana P. Belova, Ekaterina P. Mochalova, Tatiana L. Nemirovskaya, Elizabeth A. Shenkman, Ivan M. Vikhlyantsev · 2020 · Bulletin of Experimental Biology and Medicine
- Foxo1 nucleo-cytoplasmic distribution and unidirectional nuclear influx are the same in nuclei in a single skeletal muscle fiber but vary between fibersYewei Liu, Sarah J. Russell, Martin F. Schneider · 2017 · American Journal of Physiology-Cell Physiology
- G9a promotes muscular atrophy in chronic aging and acute denervationYing Jin, Wei Kang, Xiaolong Ji, Yihao Zhou, Ling Zheng · 2024 · Animal Diseases
- Muscle Disuse AtrophyDongwook Yeo · 2025 · Advances in experimental medicine and biology
- Cancer CachexiaMelissa Puppa, James A. Carson · 2025 · Advances in experimental medicine and biology
- Epigenetic Signatures of Human Myocardium and Brown Adipose Tissue Revealed with Simultaneous Positron Emission Tomography and Magnetic Resonance of Class I Histone DeacetylasesDavid Izquierdo‐Garcia, Jacob M. Hooker, Frederick A. Schroeder, Choukri Mekkaoui, Tonya M. Gilbert, Marcello Panagia, Cheryl Cero, Lindsey Rogers, Anisha Bhanot, Changning Wang et al. · 2020 · medRxiv
- Effects of 4-aminopyridine as an Adjuvant Therapy Following Peripheral Nerve Repair in an Animal Model of Nerve Transection InjuryJung Il Lee, Dong Whan Kim, Jong Woong Park, Duk Hee Lee · 2025 · Journal of Reconstructive Microsurgery
- Epigenetics of Cisplatin ResistanceSteven G. Gray · 2015 · Elsevier eBooks
- Background and Management of Muscular AtrophyJulianna Cseri · 2020 · IntechOpen eBooks
- Modulation of the Myostatin/Follistatin Axis by Deacetylase Inhibitors: Improvement of TNFα-Induced Myotube Atrophy But Not of Experimental Cancer Cachexia2014 · BENTHAM SCIENCE PUBLISHERS eBooks
- WITHDRAWN: Relationship between the regulation of muscle atrophy and mitochondrial turnover during chronic disuseLiam D. Tryon, Anna Vainshtein, Jonathan Matthew Memme, Matthew J. Crilly, David Albert Hood · 2016 · Integrative Medicine Research
- Resistance Training Alleviates Skeletal Muscle Atrophy in Rats Exposed to Hypoxia by inhibiting Autophagy Mediated by Acetyl-FoxO1Pengyu Fu, KONG Zhaowei, GONG Lijing, Hans‐Christer Holmberg, Yanchun Li, Jiabei Yu, ZHU Rongxin, Jie Jia, Yang Hu · 2020
- The Role of Histone Deacetylases I and IIa (HDAC1, HDAC4/5) and the MAPK38 Signaling Pathway in the Regulation of Atrophic Processes under Skeletal Muscle UnloadingTatiana L. Nemirovskaya · 2021 · Journal of Evolutionary Biochemistry and Physiology
- A Combination of Formoterol and the Histone Deacetylase Inhibitor AR42 has No Effects on Muscle Mass in Tumor-Bearing RatsSı́lvia Busquets, Marta Castillejo, Queralt Jové, Alina Noguera, Francisco Javier López-Soriano, Josep María Adell Argilés, Sı́lvia Busquets · 2021
- The Molecular Mechanisms and Treatment of Cancer-Related CachexiaYongfei YOU, Yong WANG, Guohua Zhang, Yong Li · 2025 · Journal of Nutritional Science and Vitaminology
- Histone Acetylation/Deacetylation and Exercise: Epigenetic Mechanisms Underlying Skeletal Muscle Health and AgingShuang Hao, Yumeng Hu, Lining Zhang, Jia Li · 2025 · Epigenetics and human health
- The role and mechanism of histone deacetylase in COPDHuifang Tang, Qian Gao, Xie Shu · 2026 · Molecular and Cellular Biochemistry
- Advances in epigenetic factors in cancer cachexia associated-muscle atrophyLi Li, Junaid Wazir, Fei Wang, Xiaolu Jin, Ranran Wang, Kai Lin, Zhiqiang Huang, Shiyu Song, Zhenghong Yu, Hongwei Wang · 2026 · Genes & Diseases
- Intramyocellular lipid droplet–mitochondria uncoupling drives muscle atrophy via metabolite-directed epigenetic reprogramming: a reviewLingfeng Wu, Ye Wang, Kailian Ma, Yang Liu · 2026 · Frontiers in Endocrinology