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Cited by 140Insect Resistance and GeneticsEntomopathogenic Microorganisms in Pest ControlInsect symbiosis and bacterial influences

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

Recombinant bacteria for mosquito control

Federici, B. A., Park, H.-W., Bideshi, D. K., Wirth, M. C., Johnson, J. J.·2003·Journal of Experimental Biology
DOI 10.1242/jeb.00643
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Abstract

SUMMARY: Bacterial insecticides have been used for the control of nuisance and vector mosquitoes for more than two decades. Nevertheless, due primarily to their high cost and often only moderate efficacy, these insecticides remain of limited use in tropical countries where mosquito-borne diseases are prevalent. Recently, however, recombinant DNA techniques have been used to improve bacterial insecticide efficacy by markedly increasing the synthesis of mosquitocidal proteins and by enabling new endotoxin combinations from different bacteria to be produced within single strains. These new strains combine mosquitocidal Cry and Cyt proteins of Bacillus thuringiensiswith the binary toxin of Bacillus sphaericus, improving efficacy against Culex species by 10-fold and greatly reducing the potential for resistance through the presence of Cyt1A. Moreover, although intensive use of B. sphaericus against Culex populations in the field can result in high levels of resistance, most of this can be suppressed by combining this bacterial species with Cyt1A; the latter enables the binary toxin of this species to enter midgut epithelial cells via the microvillar membrane in the absence of a midgut receptor. The availability of these novel strains and newly discovered mosquitocidal proteins, such as the Mtx toxins of B. sphaericus, offers the potential for constructing a range of recombinant bacterial insecticides for more effective control of the mosquito vectors of filariasis, Dengue fever and malaria.

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Registry

Crossref · 10.1242/jeb.00643

Cites

42 of 42 references verified0 citation errors · 0 not checkable

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Claims other papers make about this one

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  • There are several biological agents that have been shown to cause mortality in mosquitoes including algae, oomycetes, bacteria, microsporidian and gregarine parasites, pathogenic viruses, nematodes, predatory insects, copepods, fish and others.

    “There are several biological agents that have been shown to cause mortality in mosquitoes including algae [141,142], oomycetes [143,144], bacteria (Bti, Ls, and recombinant bacteria) [145,146], microsporidian and gregarine parasites [147,148], pathogenic viruses [145], nematodes [149], predatory insects [150,151] including other mosquitoes [152,153], copepods [154,155], fish [156,157] and others.”

    From North American Wetlands and Mosquito Control (2012) · cites this paper as [146]

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Research works printed but not linked: 1

  1. Becker, N. and Margalit, J. (1993). Use of Bacillus thuringiensis israelensis against mosquitoes and blackflies. In Bacillus thuringiensis, An Environmental Biopesticide: Theory and Practice (ed. P. F. Entwistle, J. S. Cory, M. J. Bailey and B. J. Higgs), pp. 147-170. New York: John Wiley &Sons.

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Metadata

Authors
Federici, B. A., Park, H.-W., Bideshi, D. K., Wirth, M. C., & Johnson, J. J.
Affiliations
University of California, Riverside (US)
ORCID
Venue
Journal of Experimental Biology
Publisher
The Company of Biologists
Published
2003-11-01
Volume
206
Issue
21
Pages
3877-3885
ISSN
  • 0022-0949 (ISSN-L)
  • 1477-9145
DOI
10.1242/jeb.00643
OpenAlex
W2119983100
Cited by
140
References
42
Citations by year
2025: 2 · 2024: 3 · 2023: 6 · 2021: 5 · 2020: 10 · 2019: 3 · 2018: 5 · 2017: 7 · 2016: 6 · 2015: 13 · 2014: 6 · 2013: 8 · 2012: 7
FWCI
0.47
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Experimental Biology (publishedVersion)
  • PubMed (publishedVersion)
  • HighWire Press Open Archive (submittedVersion)
Funders
National Institute of Allergy and Infectious Diseases (AI 45817, R01AI045817)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Insect Resistance and Genetics
  • Life Sciences › Agricultural and Biological Sciences › Insect Science › Entomopathogenic Microorganisms in Pest Control
  • Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect symbiosis and bacterial influences
Keywords
mosquito control, Bacillus thuringiensis, Bacillus sphaericus, Cry proteins, binary toxin, Culex, insecticide resistance, midgut epithelium, mosquito-borne diseases, filariasis, dengue, malaria
MeSH terms
Bacillus thuringiensis Toxins, Animals, Bacillus, Bacterial Proteins, Bacterial Toxins, Culex, Endotoxins, Hemolysin Proteins, Mosquito Control, Recombinant Proteins

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