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Boundary lubrication in vivo

Hills, B A·2000·Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
DOI 10.1243/0954411001535264
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Abstract

Evidence is reviewed for the concept that the body employs essentially the same lubrication system in many sites in the body where tissues slide over each other with such ease. This system consists of fluid adjacent to surfaces coated with an oligolamellar lining of surface-active phospholipid (SAPL) acting as a back-up boundary lubricant wherever the fluid film fails to support the load—a likely event at physiological velocities. Particular attention is paid to the load-bearing joints, where the issue of identifying the vital active ingredient in synovial fluid is reviewed, coming down—perhaps predictably—in favour of SAPL. It is also explained how Lubricin and hyaluronic acid (HA) could have ‘carrier’ functions for the highly insoluble SAPL, while HA has good wetting properties needed to promote hydrodynamic lubrication of a very hydrophobic articular surface by an aqueous fluid wherever the load permits. In addition to friction and wear, release is included as another major role of boundary lubricants, especially relevant in environments where proteins are found, many having adhesive properties. The discussion is extended to a mention of the lubrication of prosthetic implants and to disease states where a deficiency of boundary lubricant is implicated, particular attention being paid to osteoarthritis.

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  1. 10.1016/0043-1648(62)90176-X · DOI · Paper page
  2. Hern J. F., 1978, In Paper Coating Additives, 80
  3. 10.1152/jappl.1992.73.3.1034 · DOI
  4. 10.1007/BF02584258 · DOI
  5. Hills B. A., 1984, Ann. Rheum. Dis., 48, 51
  6. Hills B. A., 1992, Med. Sci. Res., 20, 543
  7. 10.1111/j.1440-1746.1996.tb00083.x · DOI
  8. Larsen R. G., 1968, Standard Handbook of Lubrication Engineering
  9. Stribeck R., 1902, Zeitschrift d. Vereins Deutscher, Ingenieure, 46, 1341
  10. Charnley J. Lubrication of animal joints. In Proceedings of IMechE Conference on Biomechanics, London, 1959, pp. 12–22.
  11. 10.1016/S0140-6736(00)56557-X · DOI
  12. Balazs E. A., 1984, Cosmetics and Toiletries, 99, 65
  13. 10.1136/thx.40.1.1 · DOI
  14. 10.1152/physrev.1972.52.1.57 · DOI
  15. Winters W. L., 1971, Cardiac and Vascular Diseases, 1326
  16. 10.1016/S0022-5223(19)32645-5 · DOI
  17. 10.1177/089686089801800203 · DOI
  18. Campbell M. E., 1971, A Review of Solid Lubrication Technology, 1
  19. Adamson A. W., Physical Chemistry of Surfaces, 10.1149/1.2133374 · DOI · Paper page
  20. 10.1021/ie50535a048 · DOI
  21. 10.1126/science.581915 · DOI
  22. 10.1016/0005-2760(68)90037-4 · DOI
  23. Hills B. A., 1988, The Biology of Surfactant
  24. 10.1016/S0950-3579(88)80017-7 · DOI
  25. Jungermann E., 1969, Cationic Surfactants, 4, 1
  26. Prankerd T. A. J. The Red Cell, 1961, pp. 86–87 (Blackwell, Oxford).
  27. Briscoe B. J., 1980, Adhesion, 68
  28. Fancutt F., Hudson J. C. Protective Painting of Structural Steel, 1957, pp. 28–29 (Macmillan, London).
  29. Salomon G., 1965, Adhesion and Adhesives, 1
  30. 10.1136/gut.39.5.621 · DOI
  31. 10.1136/thx.51.8.773 · DOI
  32. 10.1136/ard.47.9.754 · DOI
  33. Wright V., 1969, Lubrication and Wear in Joints, 15
  34. 10.1093/rheumatology/37.5.532 · DOI
  35. Barwell F. T., 1968, In Standard Handbook of Lubrication Engineering
  36. 10.1093/rheumatology/37.2.143 · DOI
  37. 10.1046/j.1440-1622.1999.01578.x · DOI
  38. 10.1016/0002-9378(84)90612-4 · DOI
  39. 10.1007/BF02584218 · DOI
  40. Hills B. A., 1989, J. Rheum., 16, 82
  41. Hills B. A., 1986, Obstetrics and Gynecology, 68, 550
  42. Hardy W. B., 1935, Collected Papers
  43. 10.1115/1.3426243 · DOI
  44. 10.1083/jcb.17.1.19 · DOI · Paper page
  45. 10.1083/jcb.74.3.726 · DOI
  46. Hills B. A., 1990, J. Rheum., 17, 349
  47. Ueda S., 1985, J. Japan. Med. Soc. Biol. Interface, 16, 34
  48. 10.1177/37.11.2809174 · DOI
  49. 10.1136/fn.79.3.F221 · DOI
  50. Stratton C. J., 1984, Pulmonary Surfactant, 68
  51. 10.1093/rheumatology/34.1.13 · DOI
  52. 10.1093/rheumatology/35.9.821 · DOI
  53. 10.1038/1841285a0 · DOI
  54. 10.1243/EMED_JOUR_1986_015_019_02 · DOI
  55. McCutchen C. W. Lubrication of and by articular cartilage. In Cartilage (Ed. Hall B. K.), 1983, Vol. 3, pp. 87–107 (Academic, New York). · DOI
  56. 10.1113/jphysiol.1974.sp010659 · DOI
  57. Gvozdanovic D., 1975, Ann. Rheum. Dis., 34, 100
  58. McCutchen C. W., 1978, The Joints and Synovial Fluid, 1, 437
  59. 10.1113/jphysiol.1953.sp004842 · DOI · Paper page
  60. McCutchen C. W., 1967, Proc. Instn Mech. Engrs, Part 3 J, 181, 52
  61. Davis W. H., 1979, J. Biomed. Engng, 101, 185
  62. McCutchen C. W., 1966, Federation Proc., 25, 1061
  63. 10.1002/art.1780110510 · DOI
  64. 10.1038/228377a0 · DOI
  65. 10.1002/art.1780240104 · DOI
  66. 10.1042/bj1610473 · DOI
  67. 10.1093/rheumatology/37.1.21 · DOI
  68. 10.1042/bj2250195 · DOI · Paper page
  69. 10.1002/art.1780110510 · DOI
  70. 10.1038/2191050a0 · DOI
  71. 10.1093/oxfordjournals.rheumatology.a031463 · DOI
  72. Silverstone G. A., 1985, Diet-related Diseases: The Modern Epidemic, 25
  73. Mooney W., Textile Month, 1980
  74. 10.1172/JCI114670 · DOI
  75. 10.1152/jappl.1999.87.5.1567 · DOI
  76. 10.1007/BF02368318 · DOI
  77. Little T., 1969, Lubrication and Wear in Joints, 110
  78. 10.1172/JCI105423 · DOI
  79. Rabinowitz J. L., 1984, Clinical Orthopaedics and Related Res., 190, 292, 10.1097/00003086-198411000-00052 · DOI
  80. 10.1152/jappl.1994.77.3.1217 · DOI
  81. 10.1016/0049-0172(91)90018-U · DOI
  82. 10.1007/978-3-642-73305-5_13 · DOI
  83. 10.1016/0006-3002(63)90792-3 · DOI · Paper page
  84. 10.1016/S0043-1648(96)07482-0 · DOI
  85. Hills B. A., 1990, Lymphology, 23, 39
  86. Dowson D., 1981, An Introduction to the Biomechanics of Joints and Joint Replacement
  87. 10.1006/jsbi.1997.3908 · DOI

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Metadata

Authors
Hills, B. A.
Venue
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
Publisher
SAGE Publications
Published
2000-01-01
Volume
214
Issue
1
Pages
83-94
ISSN
  • 0954-4119 (ISSN-L)
  • 2041-3033
DOI
10.1243/0954411001535264
OpenAlex
W2012185184
Cited by
253
References
0
FWCI
26.32
Type
journal article
Language
en
Open access
closed
Licence
journals.sagepub.com/page/policies/text-and-data-mining-license (tdm)

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Hills, B. A. (2000). Boundary lubrication in vivo. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine. https://doi.org/10.1243/0954411001535264

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