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Anti-Helicobacter pylori Activity of Herbal Medicines.
Open accessAbstract
The extracts of Coptidis japonica (rhizoma), Eugenia caryophyllata (flower), Rheum palmatum (rhizoma), Magnolia officinalis (cortex) and Rhusjavanica (galla rhois) potently inhibited the growth of Helicobacter pylori (HP). However, these herbal extracts showed no inhibitory effect on HP urease except Galla rhois. Among the components separated from active herbal extracts by silica gel column chromatography, the inhibitory effects of decursinol angelate and decursin on the growth of HP were the most potent, followed by magnolol, berberine, cinnamic acid, decursinol and gallic acid. Minimum inhibitory concentrations (MICs) of decursin and decursinol angelate were 6-20 microg/ml.
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Cited by
In vitro anti-Helicobacter pylori action of 30 Chinese herbal medicines used to treat ulcer diseases
Li, Y., Xu, C., Zhang, Q., Liu, J. Y., & Tan, R. X. (2005) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2005.01.020 · Cited by 256
Potent anti‐microbial activity of traditional Chinese medicine herbs against Candida species
Seneviratne, C. J., Wong, R. W. K., & Samaranayake, L. P. (2008) · Mycoses · doi:10.1111/j.1439-0507.2007.01431.x · Cited by 51
Metadata
- Authors
- BAE, E.-A., HAN, M. J., KIM, N.-J., & KIM, D.-H.
- Venue
- Biological and Pharmaceutical Bulletin
- Publisher
- Pharmaceutical Society of Japan
- Published
- 1998
- Volume
- 21
- Issue
- 9
- Pages
- 990-992
- ISSN
- 0918-6158 (ISSN-L)
- 1347-5215
- OpenAlex
- W2082888592
- Cited by
- 175
- References
- 0
- FWCI
- 2.59
- Type
- journal article
- Language
- en
- Open access
- bronze
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- BAE, E.-A., HAN, M. J., KIM, N.-J., & KIM, D.-H. (1998). Anti-Helicobacter pylori Activity of Herbal Medicines. Biological and Pharmaceutical Bulletin. https://doi.org/10.1248/bpb.21.990
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