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Cited by 138Ginger and Zingiberaceae researchGastrointestinal motility and disordersGinseng Biological Effects and Applications

The DOI matches its Crossref record.

Gastrointestinal motility enhancing effect of ginger and its active constituents.

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YAMAHARA, Johji, HUANG, Qirong, LI, Yuhao, XU, Lin, FUJIMURA, Hajime·1990·Chemical and Pharmaceutical Bulletin
DOI 10.1248/cpb.38.430
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Abstract

The effect of ginger root (Zingiberis Rhizoma) on gastrointestinal motility was examined based on its ability to enhance charcoal meal transport in mice. Oral administrations of the acetone extract of ginger (which contains volatile oils and bitter substances) at 75 mg/kg, [6]-shogaol at 2.5 mg/kg, or a [6]-, [8]- or [10]-gingerol at 5 mg/kg enhanced the transport of a charcoal meal. The effects of these substances were similar to or slightly weaker than those of metoclopramide and donperidone.

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Research works printed but not linked: 6

  1. [2]J. Yamahara, Q. R. Huang, M. Iwamoto, G. Kobayashi, H. Matsuda and H. Fujimura, Phytotherapy Research, 3, 70 (1989).
  2. [1]M. Aburada, J. Traditional Sino-Japanese Medicine, 8, 45 (1987).
  3. [3]J. Yamahara, Q. R. Huang, Y. Naitoh, T. Kitani and H. Fujimura, J. Ethnopharmacology, 27(3), 353 (1989).
  4. [5]F. D. King and G. J. Sanger, "Annual Reports in Medicinal Chemistry," Vol. 23, Academic Press, Inc., California, 1988, p. 201.
  5. [4]M. S. Hadiey, F. D. King, B. McRitchie, D. H. Turner and E. A. Watts, J. Med. Chem., 28, 1843 (1985).
  6. [6]Y. Kasahara, E. Saito and H. Hikino, Shoyakugaku Zasshi, 37, 73 (1983).

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Metadata

Authors
YAMAHARA, J., HUANG, Q., LI, Y., XU, L., & FUJIMURA, H.
Affiliations
Kyoto Pharmaceutical University (JP)
ORCID
Venue
Chemical and Pharmaceutical Bulletin
Publisher
Pharmaceutical Society of Japan
Published
1990
Volume
38
Issue
2
Pages
430-431
ISSN
  • 0009-2363 (ISSN-L)
  • 1347-5223
DOI
10.1248/cpb.38.430
OpenAlex
W2037992963
Cited by
138
References
0
Citations by year
2025: 2 · 2024: 4 · 2023: 3 · 2022: 4 · 2021: 7 · 2020: 6 · 2019: 9 · 2018: 3 · 2017: 4 · 2016: 11 · 2015: 8 · 2014: 4 · 2013: 8 · 2012: 3
FWCI
0.81
Type
journal article
Language
en
Open access
Locations
  • Chemical and Pharmaceutical Bulletin (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Ginger and Zingiberaceae research
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Ginseng Biological Effects and Applications
Keywords
ginger, Zingiberis Rhizoma, gastrointestinal motility, 6-shogaol, gingerol, essential oils, bitter compounds, metoclopramide, prokinetic agents
MeSH terms
Animals, Catechols, Condiments, Fatty Alcohols, Gastrointestinal Motility, Male, Plant Extracts, Mice

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