Pulsed Electromagnetic Fields Increase Angiogenesis and Improve Cardiac Function After Myocardial Ischemia in Mice
Open accessAbstract
BACKGROUND: Previous studies have shown that pulsed electromagnetic fields (PEMF) stimulate angiogenesis and may be a potential treatment strategy to improve cardiac function after myocardial infarction (MI). This study explored the effects and its related mechanisms of PEMF in MI mice. METHODS AND RESULTS: -eNOS), and increased the mRNA level of VEGF and hypoxia inducible factor 1-alpha (HIF-1α) in the infarct border zone. Additionally, treatment with 30 Hz 3.0 mT also increased protein and mRNA level of fibroblast growth factor 2 (FGF2), and protein level of β1 integrin, and shows a stronger therapeutic effect. CONCLUSIONS: PEMF treatment could promote angiogenesis of the infarct border zone and improve cardiac function in MI mice. A treatment parameter of 30 Hz 3.0 mT is remarkably effective in MI mice. The effect is associated with the proangiogenic signaling pathways of HIF-1α/VEGF/Akt/eNOS or HIF-1α/FGF2/Akt/eNOS.
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In preclinical models of myocardial infarction and ischemia-reperfusion injury, PEMF improves cardiac function, limits remodeling, and enhances angiogenesis.
“In preclinical models of myocardial infarction and ischemia–reperfusion injury, PEMF improved cardiac function, limited remodeling and enhanced angiogenesis [7,8,9,148].”
From The Heart’s Electromagnetic Field in Emotions, Empathy and Human Connection: Biosensor-Derived Insights into Heart–Brain Axis Mechanisms and a Basis for Novel BioMagnetoTherapies (2026) · cites this paper as [8]
The Discussion and the sections on cardiac function and infarct area report that PEMF improved function, reduced infarct size and increased angiogenesis in mice after myocardial infarction; the conclusion also says it limited infarct expansion. The Animals and MI Model section describes coronary-artery ligation, not an ischemia–reperfusion injury model, so this source does not support that part of the citing sentence. Page numbers were not available in our copy. (LLM, conf=0.87)
Experimental — accuracy not yet measuredPEMF therapy has cardioprotective and neuroprotective potential via enhancing cell survival, reducing inflammation and fibrosis, and promoting vascular repair and neuroplasticity.
“Pulsed electromagnetic field (PEMF) therapy has demonstrated cardioprotective and neuroprotective potential via enhancing cell survival, reducing inflammation and fibrosis and promoting vascular repair and neuroplasticity [7,8,9,10].”
From The Heart’s Electromagnetic Field in Emotions, Empathy and Human Connection: Biosensor-Derived Insights into Heart–Brain Axis Mechanisms and a Basis for Novel BioMagnetoTherapies (2026) · cites this paper as [8]
The Discussion reports reduced infarct size and improved cardiac function in mice after myocardial infarction, associated with increased angiogenesis; this supports cardioprotective potential and vascular repair. The paper says enhanced cardiomyocyte survival still needs investigation, and the cited passages do not establish reduced inflammation or fibrosis, neuroprotection, or neuroplasticity. (LLM, conf=0.87)
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Cites
Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association
Mozaffarian, D., Benjamin, E. J., Go, A. S., Arnett, D. K., Blaha, M. J., Cushman, M., Das, S. R., de Ferranti, S., Després, J.-P., Fullerton, H. J., et al. (2016) · Circulation · doi:10.1161/cir.0000000000000350 · Cited by 6,596 · see citing works
Angiogenesis as a therapeutic target
Ferrara, N., & Kerbel, R. S. (2005) · Nature · doi:10.1038/nature04483 · Cited by 2,653 · see citing works
Left Ventricular Remodeling After Myocardial Infarction
Sutton, M. G. S. J., & Sharpe, N. (2000) · Circulation · doi:10.1161/01.cir.101.25.2981 · Cited by 1,827 · see citing works
Signal Transduction by Vascular Endothelial Growth Factor Receptors
Koch, S., Tugues, S., Li, X., Gualandi, L., & Claesson, L. (2011) · Biochemical Journal · doi:10.1042/bj20110301 · Cited by 1,629 · see citing works
Shiojima, I. (2005) · Journal of Clinical Investigation · doi:10.1172/jci24682 · Cited by 935 · see citing works
A Novel and Efficient Model of Coronary Artery Ligation and Myocardial Infarction in the Mouse
Gao, E., Lei, Y. H., Shang, X., Huang, Z. M., Zuo, L., Boucher, M., Fan, Q., Chuprun, J. K., Ma, X. L., & Koch, W. J. (2010) · Circulation Research · doi:10.1161/circresaha.110.223925 · Cited by 769 · see citing works
Fourth Universal Definition of Myocardial Infarction (2018)
Thygesen, K. A., Alpert, J. S., Jaffe, A. S., CHAITMAN, B. R., Bax, J. J., Morrow, D. A., & White, H. D. (2018) · Global Heart · doi:10.1016/j.gheart.2018.08.004 · Cited by 473 · see citing works
Molecular mechanisms of blood vessel formation
Bussolino, F., Mantovani, A., & Persico, G. M. (1997) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(97)01074-8 · Cited by 467 · see citing works
Nishida, T., Shimokawa, H., Oi, K., Tatewaki, H., Uwatoku, T., Abe, K., Matsumoto, Y., Kajihara, N., Eto, M., Matsuda, T., et al. (2004) · Circulation · doi:10.1161/01.cir.0000148849.51177.97 · Cited by 382 · see citing works
The Link Between Angiogenesis and Endothelial Metabolism
Potente, M., & Carmeliet, P. (2016) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021115-105134 · Cited by 353 · see citing works
Human Studies of Angiogenic Gene Therapy
Gupta, R., Tongers, J., & Losordo, D. W. (2009) · Circulation Research · doi:10.1161/circresaha.109.200386 · Cited by 273 · see citing works
Stewart, D. J., Kutryk, M. J. B., Fitchett, D., Freeman, M. R., Camack, N., Su, Y., Siega, A. D., Bilodeau, L., Burton, J. R., Proulx, G., et al. (2009) · Molecular Therapy · doi:10.1038/mt.2009.70 · Cited by 266 · see citing works
Schmidt, C., Pommerenke, H., Dürr, F., Nebe, B. J., & Rychly, J. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.9.5081 · Cited by 216 · see citing works
Tepper, O. M., Callaghan, M. J., Chang, E. I.-F., Galiano, R. D., Bhatt, K. A., Baharestani, S., Gan, J. C., Simon, B. J., Hopper, R. A., Levine, J. P., et al. (2004) · The FASEB Journal · doi:10.1096/fj.03-0847fje · Cited by 200 · see citing works
Yen‐Patton, G. P. A., Patton, W. F., Beer, D. M., & Jacobson, B. S. (1988) · Journal of Cellular Physiology · doi:10.1002/jcp.1041340105 · Cited by 162 · see citing works
Callaghan, M. J., Chang, E. I.-F., Seiser, N., Aarabi, S., Ghali, S., Kinnucan, E. R., Simon, B. J., & Gurtner, G. C. (2008) · Plastic & Reconstructive Surgery · doi:10.1097/01.prs.0000293761.27219.84 · Cited by 155 · see citing works
Thamsborg, G., Florescu, A., Oturai, P., Fallentin, E., Tritsaris, K., & Dissing, S. (2005) · Osteoarthritis and Cartilage · doi:10.1016/j.joca.2005.02.012 · Cited by 129 · see citing works
Hanawa, K., Ito, K., Aizawa, K., Shindo, T., Nishimiya, K., Hasebe, Y., Tuburaya, R., Hasegawa, H., Yasuda, S., Kanai, H., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0104863 · Cited by 115 · see citing works
Uwatoku, T., Ito, K., Abe, K., Oi, K., Hizume, T., Sunagawa, K., & Shimokawa, H. (2007) · Coronary Artery Disease · doi:10.1097/mca.0b013e328089f19b · Cited by 98 · see citing works
Chalidis, B. E., Sachinis, N. P., Assiotis, A., Maccauro, G., & Graziani, F. (2011) · International Journal of Immunopathology and Pharmacology · doi:10.1177/03946320110241s204 · Cited by 97 · see citing works
Shindo, T., Ito, K., Ogata, T., Hatanaka, K., Kurosawa, R., Eguchi, K., Kagaya, Y., Hanawa, K., Aizawa, K., Shiroto, T., et al. (2016) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.115.306477 · Cited by 97 · see citing works
Ahn, D., Cheng, L., Moon, C., Spurgeon, H. A., Lakatta, E. G., & Talan, M. I. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00862.2003 · Cited by 93 · see citing works
Hatanaka, K., Ito, K., Shindo, T., Kagaya, Y., Ogata, T., Eguchi, K., Kurosawa, R., & Shimokawa, H. (2016) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00152.2016 · Cited by 93 · see citing works
Coronary reserve is depressed in postmyocardial infarction reactive cardiac hypertrophy.
Karam, R., HEALY, B. P., & Wicker, P. (1990) · Circulation · doi:10.1161/01.cir.81.1.238 · Cited by 91 · see citing works
Monache, S. D., Alessandro, R., Iorio, R., Gualtieri, G., & Colonna, R. C. (2008) · Bioelectromagnetics · doi:10.1002/bem.20430 · Cited by 91 · see citing works
Abe, Y., Ito, K., Hao, K., Shindo, T., Ogata, T., Kagaya, Y., Kurosawa, R., Nishimiya, K., Satoh, K., Miyata, S., et al. (2014) · Circulation Journal · doi:10.1253/circj.cj-14-0230 · Cited by 71 · see citing works
Cheing, G. L. Y., Li, X., Huang, L., Kwan, R. L., & Cheung, K. (2014) · Bioelectromagnetics · doi:10.1002/bem.21832 · Cited by 68 · see citing works
Zhou, J. M., Chen, S., Guo, H., Xia, L., Liu, H., Qin, Y., & He, C. (2012) · Rheumatology International · doi:10.1007/s00296-012-2499-9 · Cited by 49 · see citing works
Self-citationPan, Y., Dong, Y., Hou, W., Ji, Z., Zhi, K., Yin, Z., Wen, H., & Chen, Y. (2012) · Bioelectromagnetics · doi:10.1002/bem.21755 · Cited by 45 · see citing works
Sulik, G. L., Soong, H. K., Chang, P. C.-T., Parkinson, W. C., Elner, S. G., & Elner, V. M. (1992) · Acta Ophthalmologica · doi:10.1111/j.1755-3768.1992.tb02102.x · Cited by 45 · see citing works
Kim, S. S., Shin, H. J., Eom, D., Huh, J. R., Woo, Y., Kim, H.-K., Ryu, S. H., Suh, P. G., Kim, M. J., Kim, J. Y., et al. (2002) · Experimental & Molecular Medicine · doi:10.1038/emm.2002.8 · Cited by 43 · see citing works
Endothelial β1 integrins regulate sprouting and network formation during vascular development
Malan, D., Wenzel, D., Schmidt, A., Geisen, C., Raible, A., Bölck, B., Fleischmann, B. K., & Bloch, W. (2010) · Development · doi:10.1242/dev.045377 · Cited by 42 · see citing works
Yuan, Y., Wei, L., Li, F. Y., Guo, W., Li, W., Luan, R., Lv, A., & Wang, H. (2010) · Cardiology · doi:10.1159/000321459 · Cited by 27 · see citing works
Luo, Q., Li, S., He, C., He, H., Yang, L., & Deng, L. (2008) · Rheumatology International · doi:10.1007/s00296-008-0782-6 · Cited by 25 · see citing works
Self-citationGene Therapy in Cardiac Surgery: Clinical Trials, Challenges, and Perspectives
Katz, M. G., Fargnoli, A. S., Kendle, A. P., Hajjar, R. J., & Bridges, C. R. (2016) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2015.12.004 · Cited by 25 · see citing works
Epithelial cell integrin β1 is required for developmental angiogenesis in the pituitary gland
Scully, K. M., Skowronska‐Krawczyk, D., Krawczyk, M., Merkurjev, D., Taylor, H., Livolsi, A., Tollkühn, J., Stan, R. V., & Rosenfeld, M. G. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1614970113 · Cited by 24 · see citing works
Drug-eluting coronary artery stents.
DEHMER, G. J., & Smith, K. (2009) · PubMed · Cited by 23 · see citing works
Pulsed electromagnetic field improves cardiac function in response to myocardial infarction.
Hao, C., Huang, J., Shi, Y., Cheng, X. W., Li, H.-Y., Zhou, L., Guo, X., Li, R., Lü, W., Zhu, Y. Z., et al. (2014) · Europe PMC (PubMed Central) · Cited by 22 · see citing works
Integrins may serve as mechanical transducers for low-frequency electric fields
Hart, F. X. (2006) · Bioelectromagnetics · doi:10.1002/bem.20236 · Cited by 17 · see citing works
Kagaya, Y., Ito, K., TAKAHASHI, J. C., Matsumoto, Y., Shiroto, T., Tsuburaya, R., Kikuchi, Y., Hao, K., Nishimiya, K., Shindo, T., et al. (2017) · Coronary Artery Disease · doi:10.1097/mca.0000000000000577 · Cited by 17 · see citing works
Angiogenic Growth Factors for Coronary Artery Disease: Current Status and Prospects
Guo, M. H., Shi, J., Wang, P., & Shi, D. (2017) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/1074248417735399 · Cited by 15 · see citing works
Han, J., Yan, X., Han, Q., Li, Y., Zhu, J., & Hui, Y.-N. (2009) · Current Eye Research · doi:10.1080/02713680902879033 · Cited by 13 · see citing works
Flagged first, then by citations
1 of the 43 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
The Effect of Pulsed Electromagnetic Fields on Angiogenesis
Peng, L., Fu, C., Wang, L., Zhang, Q., Liang, Z., He, C., & Wei, Q. (2021) · Bioelectromagnetics · doi:10.1002/bem.22330 · Cited by 49 · see citing works
Self-citationHarnessing electromagnetic fields to assist bone tissue engineering
Zhao, H., Liu, C., Liu, Y., Ding, Q., Wang, T., Li, H., Wu, H. K., & Ma, T. (2023) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-03217-z · Cited by 36 · see citing works
Wang, Q., Zhou, J. M., Wang, X., Xu, Y., Liang, Z., Gu, X., & He, C. (2021) · Bone · doi:10.1016/j.bone.2021.116211 · Cited by 30 · see citing works
Self-citationHuang, L., Sun, X., Wang, L., Pei, G., Wang, Y., Zhang, Q., Liang, Z., Wang, D., Fu, C., He, C., et al. (2022) · MedComm · doi:10.1002/mco2.160 · Cited by 22 · see citing works
Self-citationMagnetically Controlled Strategies for Enhanced Tissue Vascularization
Zhu, S., Xu, L., Zhang, Y., Zheng, Z., Lang, Z., Zhang, Q., Gao, J., Ye, M., & Xu, R. X. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202401856 · Cited by 22 · see citing works
Self-citationPhysical Treatments and Therapies for Androgenetic Alopecia
Lama, S. B. C., Pérez-González, L. A., Kosoglu, M. A., Dennis, R. G., & Ortega-Quijano, D. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13154534 · Cited by 22 · see citing works
Wang, Y., Zhao, Z., Chai, Z., Fang, J., & Chen, M. (2023) · The FASEB Journal · doi:10.1096/fj.202300201rr · Cited by 23 · see citing works
Zhang, B., Yu, P., Su, E., Jia, J., Zhang, C., Xie, S., Huang, Z., Dong, Y., Ding, J., Zou, Y., et al. (2021) · Current Pharmaceutical Design · doi:10.2174/1381612828666211224152440 · Cited by 20 · see citing works
Yang, C., Xu, L., Liao, F., Liao, C., Zhao, Y., Chen, Y., Yu, Q., Peng, B., & Liu, H. (2024) · Scientific Reports · doi:10.1038/s41598-024-69862-x · Cited by 15 · see citing works
Regulation of Inflammatory Responses by Pulsed Electromagnetic Fields
Kaadan, A., Salati, S., Cadossi, R., & Aaron, R. K. (2025) · Bioengineering · doi:10.3390/bioengineering12050474 · Cited by 13 · see citing works
Biermann, N., Sommerauer, L., Diesch, S. T., Koch, C., Jung, F., Kehrer, A., Prantl, L., & Taeger, C. D. (2020) · Clinical Hemorheology and Microcirculation · doi:10.3233/ch-209224 · Cited by 10 · see citing works
Tamulevicius, N., Wadhi, T., Oviedo, G. R., Anand, A. S., Tien, J.-J., Houston, F. E., & Vlahov, E. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18147691 · Cited by 9 · see citing works
Heng, B. C., Li, X., Guo, Y., Wu, K., Bai, Y., Liu, Y., Zhang, X., & Deng, X. (2025) · EngMedicine · doi:10.1016/j.engmed.2025.100078 · Cited by 8 · see citing works
Xu, C., Cheng, P., Wang, J., Zhang, B., Shang, P., Lv, Y., & Jie, Q. (2025) · Research · doi:10.34133/research.0707 · Cited by 7 · see citing works
Wang, Y., Chen, L., Wang, L., Pei, G., Cheng, H., Zhang, Q., Wang, S., Hu, D., He, Y., He, C., et al. (2023) · Stem Cells · doi:10.1093/stmcls/sxad037 · Cited by 7 · see citing works
Self-citationWang, S., Pei, G., Shen, J., Fang, Z., Chen, T., Wang, L., Cheng, H., Li, H., Pei, H., Feng, Q., et al. (2026) · Journal of Advanced Research · doi:10.1016/j.jare.2025.04.019 · Cited by 6 · see citing works
“Because our previous study revealed that 30 Hz, 3.0 mT PEMF treatment was bene-ficial for the treatment of MI, this study used this parameter for intervention, and the treatment time was 45 min per day [13].”
InfluentialSelf-citationCheng, H., Zhang, Q. H., Zhong, W., Li, H., Wang, L., Wang, S., He, C., Fu, C., & Wei, Q. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02479-2 · Cited by 6 · see citing works
Self-citationUngureanu, A. E., Stanciu, L.-E., Uzun, A.-B., Gheorghe, E., Pazara, L., Miclaus, S.-R., Ciortea, V. M., Suceveanu, A., & Iliescu, M. G. (2023) · Balneo and PRM Research Journal · doi:10.12680/balneo.2023.579 · Cited by 6 · see citing works
Ahmad, A., & Mahmoud, R. R. (2021) · Advances in Rehabilitation · doi:10.5114/areh.2021.109710 · Cited by 5 · see citing works
Muraev, A. A., Manukyan, G. G., Salekh, K. M., Bonartsev, A. P., & Volkov, A. V. (2024) · RUDN Journal of Medicine · doi:10.22363/2313-0245-2024-28-1-9-22 · Cited by 4 · see citing works
Kämmerer, P. W., Engel, N., Bader, R., Engel, V., Frerich, B., Heimes, D., Kröger, J., Lembcke, L., Plocksties, F. V., Raben, H., et al. (2025) · Clinical Oral Investigations · doi:10.1007/s00784-025-06303-7 · Cited by 4 · see citing works
Local Injection of Hydroxyapatite Electret Ameliorated Infarct Size After Myocardial Infarction
Yamaguchi, J., Chiba, R., Komuro, H., Ihara, K., Nozaki, K., Nagai, A., Furukawa, T., & Sasano, T. (2021) · Circulation Reports · doi:10.1253/circrep.cr-21-0100 · Cited by 2 · see citing works
The Effect of a Rotating Magnetic Field on the Regenerative Potential of Platelets
Cecerska-Heryć, E., Goszka, M., Gliźniewicz, M., Grygorcewicz, B., Serwin, N., Stodolak, P., Słodzińska, W., Birger, R., Polikowska, A., Budkowska, M., et al. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25073644 · Cited by 2 · see citing works
Palantzas, A., & Anagnostouli, M. (2026) · Sensors · doi:10.3390/s26051738 · Cited by 1 · see citing works
Effects of wireless local area network exposure on testicular morphology and VEGF levels
Çakmak, E., Bilgici, B., Engiz, B. K., & Kocaman, A. (2026) · Scientific Reports · doi:10.1038/s41598-026-37323-2 · Cited by 1 · see citing works
Alghadier, M., Abuzaid, I. I., & Elgohary, H. M. (2026) · Healthcare · doi:10.3390/healthcare14060796 · Cited by 1 · see citing works
Owens, C. V., Najjar, R. S., Bruce, M. A., Beech, B. M., & Montgomery, B. D. (2024) · American Journal of Lifestyle Medicine · doi:10.1177/15598276241281475 · Cited by 1 · see citing works
Ghasemi, F., Namjoo, M., ashabi, F., Niknejad, N., Ebrahimi, M., Khatib, A., Tezerji, S., & Moradabadi, M. M. (2023) · Research Square · doi:10.21203/rs.3.rs-2613664/v1 · Cited by 1 · see citing works
Farhat, K., & Stavrakis, S. (2021) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2021.10.008
Электро- и магнитоактивные материалы для биоинженерии
Voinova, V. V., Жаркова, И. И., & Бонарцев, А. П. (2023) · doi:10.15862/47mnnpu23
Hammoud, A., Briko, A. N., Kapravchuk, V. V., Malakhov, A. I., & Shchukin, S. I. (2026) · Bioengineering · doi:10.3390/bioengineering13101160
Malhotra, D. R., Mardhian, D. F., An, L. M. L. J., Sabino, C. F., Yu, B., Ruangsawasdi, N., Silva, P. H. S. E., Iversen, J. N., Razar, R. B. B. A., Sim, Y. F., et al. (2026) · Biomaterials and Biosystems · doi:10.1016/j.bbiosy.2026.100151
- Authors
- Peng, L., Fu, C., Liang, Z., Zhang, Q., Xiong, F., Chen, L., He, C., & Wei, Q.
- Affiliations
- Sichuan University (CN)
- Venue
- Circulation Journal
- Publisher
- Japanese Circulation Society
- Published
- 2020-01-24
- Volume
- 84
- Issue
- 2
- Pages
- 186-193
- ISSN
- 1346-9843 (ISSN-L)
- 1347-4820
- OpenAlex
- W3000282234
- Cited by
- 32
- References
- 43
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 6 · 2023: 6 · 2022: 1 · 2021: 7 · 2020: 1
- FWCI
- 1.78
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Locations
- Circulation Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (81572231)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Electromagnetic Fields and Biological Effects
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Fibrosis and Remodeling
- Health Sciences › Medicine › Pathology and Forensic Medicine › Cardiac Ischemia and Reperfusion
- Keywords
- pulsed electromagnetic fields, myocardial ischemia, myocardial infarction, angiogenesis, cardiac function, infarct border zone, HIF-1α, vascular endothelial growth factor, endothelial nitric oxide synthase, FGF2, beta1 integrin, Akt signaling
- MeSH terms
- Animals, Disease Models, Animal, Electromagnetic Fields, Mice, Inbred C57BL, Myocardial Infarction, Myocardium, Phosphorylation, Signal Transduction, Fibroblast Growth Factor 2, Ventricular Function, Left, Neovascularization, Physiologic, Recovery of Function, Vascular Endothelial Growth Factor Receptor-2, Vascular Endothelial Growth Factor A, Angiogenic Proteins, Proto-Oncogene Proteins c-akt, Hypoxia-Inducible Factor 1, alpha Subunit, Nitric Oxide Synthase Type III, Magnetic Field Therapy
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