Neuropsychotoxicity of abused drugs: effects of serotonin receptor ligands on methamphetamine- and cocaine-induced behavioral sensitization in mice
Open accessAbstract
Repeated administration of psychostimulants elicits a progressive enhancement of locomotor activity known as behavioral sensitization. Central dopamine (DA) neurons play key roles as the neural substrates mediating behavioral sensitization, but the role of the serotonin (5-HT) system in the sensitization is not fully elucidated. We have recently demonstrated that osemozotan, a specific 5-HT(1A)-receptor agonist, and ritanserin, a 5-HT(2)-receptor antagonist, inhibited the expression and development of both methamphetamine- and cocaine-induced behavioral sensitization in mice and that these drugs attenuated the maintenance of behavioral sensitization of methamphetamine, but not that of cocaine. We also found that azasetron, a 5-HT(3)-receptor antagonist, inhibited the expression and development of the sensitization induced by methamphetamine and cocaine, respectively. Neurochemical studies using a microdialysis technique showed that repeated methamphetamine enhanced the methamphetamine-induced increase in 5-HT release in the prefrontal cortex. The sensitization of 5-HT release in methamphetamine-treated mice was attenuated by osemozotan and ritanserin. These findings suggest that the 5-HT system plays an important role in methamphetamine- and cocaine-induced behavioral sensitization in mice and imply that 5-HT(1A)-receptor agonists and 5-HT(2)-receptor antagonists may have a potential therapeutic value for the treatment of methamphetamine abuse or psychosis.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
MDMA strongly affects 5-HT2A receptors, which are important mediators of behavioral sensitization.
“MDMA also strongly affects 5-HT2A receptors, which are important mediators of behavioral sensitization (47–49).”
From MDMA-Assisted Therapy as a Means to Alter Affective, Cognitive, Behavioral, and Neurological Systems Underlying Social Dysfunction in Social Anxiety Disorder (2021) · cites this paper as [47]
The sections on methamphetamine- and cocaine-induced behavioral sensitization report that 5-HT2A receptor antagonists inhibit sensitization, supporting a role for these receptors. The paper does not say that MDMA strongly affects 5-HT2A receptors; its findings concern other drugs. (LLM, conf=0.85)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
A review of central 5-HT receptors and their function
Barnes, N. M., & Sharp, T. (1999) · Neuropharmacology · doi:10.1016/s0028-3908(99)00010-6 · Cited by 3,150 · see citing works
Molecular basis of long-term plasticity underlying addiction
Nestler, E. J. (2001) · Nature reviews. Neuroscience · doi:10.1038/35053570 · Cited by 1,857 · see citing works
Vanderschuren, L. J. M. J., & Kalivas, P. W. (2000) · Psychopharmacology · doi:10.1007/s002130000493 · Cited by 1,337 · see citing works
A circuitry model of the expression of behavioral sensitization to amphetamine-like psychostimulants
Pierce, R. C., & Kalivas, P. W. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(97)00021-0 · Cited by 1,239 · see citing works
Wise, R. A. (2002) · Neuron · doi:10.1016/s0896-6273(02)00965-0 · Cited by 881 · see citing works
Neuroadaptations involved in amphetamine and cocaine addiction
White, F. J., & Kalivas, P. W. (1998) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(98)00072-6 · Cited by 509 · see citing works
Martín‐Ruiz, R., Puig, M. V., Celada, P., Shapiro, D. A., Roth, B. L., Mengod, G., & Artigas, F. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-24-09856.2001 · Cited by 338 · see citing works
Paulson, P. E., & Robinson, T. E. (1995) · Synapse · doi:10.1002/syn.890190108 · Cited by 337 · see citing works
Segal, D. S., & Kuczenski, R. T. (1992) · Brain Research · doi:10.1016/0006-8993(92)90672-v · Cited by 193 · see citing works
Auclair, A., Drouin, C., Cotecchia, S., Glowinski, J., & Tassin, J. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03805.x · Cited by 163 · see citing works
Filip, M., Bubar, M. J., & Cunningham, K. A. (2004) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.104.068841 · Cited by 130 · see citing works
5-Hydroxytryptamine 1a receptor agonists block prepulse inhibition of acoustic startle reflex.
Rigdon, G. C., & Weatherspoon, J. K. (1992) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)10375-3 · Cited by 127 · see citing works
Newman, A. H., Allen, A. C., Izenwasser, S., & Katz, J. L. (1994) · Journal of Medicinal Chemistry · doi:10.1021/jm00041a002 · Cited by 119 · see citing works
Salomon, L., Lanteri, C., Glowinski, J., & Tassin, J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0600839103 · Cited by 117 · see citing works
Hamamura, T., Akiyama, K., Akimoto, K., Kashihara, K., Okumura, K., Ujike, H., & Otsuki, S. (1991) · Brain Research · doi:10.1016/0006-8993(91)91156-u · Cited by 115 · see citing works
Stephans, S. E., & Yamamoto, B. K. (1995) · Brain Research · doi:10.1016/0006-8993(95)00938-m · Cited by 106 · see citing works
Sipes, T. E., & Geyer, M. A. (1995) · Psychopharmacology · doi:10.1007/bf02245096 · Cited by 103 · see citing works
Enhanced stress-induced dopamine release in the prefrontal cortex of amphetamine-sensitized rats
Hamamura, T., & Fibiger, H. C. (1993) · European Journal of Pharmacology · doi:10.1016/0014-2999(93)90094-x · Cited by 101 · see citing works
Effects of strain and serotonergic agents on prepulse inhibition and habituation in mice
Dulawa, S. C., & Geyer, M. A. (2000) · Neuropharmacology · doi:10.1016/s0028-3908(00)00030-7 · Cited by 99 · see citing works
Rothman, R. B., Grieg, N. H., Kim, A., de Costa, B. R., Rice, K. C., Carroll, F. I., & Pert, A. (1992) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(92)90493-y · Cited by 81 · see citing works
Blanchard, R. J., Griebel, G., Lemaître, B. J., Brush, M. M., Lee, J., & Blanchard, D. C. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00472-8 · Cited by 76 · see citing works
Kuczenski, R. T., Segal, D. S., & Todd, P. K. (1997) · Psychopharmacology · doi:10.1007/s002130050445 · Cited by 72 · see citing works
Regulation by 5-HT1A receptors of the in vivo release of 5-HT and DA in mouse frontal cortex
Ago, Y., Kōyama, Y., Baba, A., & Matsuda, T. (2003) · Neuropharmacology · doi:10.1016/s0028-3908(03)00304-6 · Cited by 72 · see citing works
Self-citationKing, G., Xiong, Z. Z., Douglas, S., & Ellinwood, E. H. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(99)00926-7 · Cited by 72 · see citing works
Garza, R. D. L., & Cunningham, K. A. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)35331-5 · Cited by 70 · see citing works
Müller, C. P., Carey, R. J., Silva, M. A. D. S., Jocham, G., & Huston, J. P. (2002) · Synapse · doi:10.1002/syn.10083 · Cited by 66 · see citing works
Bortolozzi, A. A., Amargós‐Bosch, M., Adell, A., Díaz-Mataix, L., Serrats, J., Pons, S., & Artigas, F. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02829.x · Cited by 62 · see citing works
Ago, Y., Nakamura, S., Uda, M., Kajii, Y., ABE, M., BABA, A., & MATSUDA, T. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.06.001 · Cited by 61 · see citing works
Self-citationNarita, M., Akai, H., Nagumo, Y., Sunagawa, N., Hasebe, K., Nagase, H., Kita, T., Hara, C., & Suzuki, T. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.06.017 · Cited by 59 · see citing works
King, G. R., Xiong, Z. Z., & Ellinwood, E. H. (1997) · Psychopharmacology · doi:10.1007/s002130050224 · Cited by 54 · see citing works
Matsuda, T., Yoshikawa, T., Suzuki, M., Asano, S., Somboonthum, P., Takuma, K., Nakano, Y., Morita, T., Nakasu, Y., Kim, H. S., et al. (1995) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.69.357 · Cited by 53 · see citing works
Self-citationMüller, C. P., Silva, M. A. D. S., DePalma, G., Tomaz, C. A. B., Carey, R. J., & Huston, J. P. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00042-6 · Cited by 50 · see citing works
Effect of serotonin (5-HT) 1B receptor ligands on cocaine sensitization in rats
Przegaliński, E., Filip, M., Papla, I., & Siwanowicz, J. (2001) · Behavioural Pharmacology · doi:10.1097/00008877-200104000-00004 · Cited by 49 · see citing works
Shuto, T., Kuroiwa, M., Hamamura, M., Yabuuchi, K., Shimazoe, T., Watanabe, S., Nishi, A., & Yamamoto, T. (2006) · Neuropharmacology · doi:10.1016/j.neuropharm.2006.01.009 · Cited by 42 · see citing works
Davidson, C., Lazarus, C., Xiong, X., Lee, T. H., & Ellinwood, E. H. (2002) · European Journal of Pharmacology · doi:10.1016/s0014-2999(02)02390-7 · Cited by 41 · see citing works
Miyata, K., Kamato, T., Yamano, M., Nishida, A., Ito, H., Katsuyama, Y., Yuki, H., Tsutsumi, R., Ohta, M., & Takeda, M. (1991) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20549-3 · Cited by 40 · see citing works
Activation of serotonin (5-HT)1A receptors inhibits amphetamine sensitization in mice
Przegaliński, E., Siwanowicz, J., Baran, L., & Filip, M. (2000) · Life Sciences · doi:10.1016/s0024-3205(99)00666-9 · Cited by 40 · see citing works
Iyo, M., Bi, Y., Hashimoto, K., Inada, T., & Fukui, S. (1996) · European Journal of Pharmacology · doi:10.1016/0014-2999(96)00479-7 · Cited by 40 · see citing works
Role of 5-HT1B receptors in the sensitization to amphetamine in mice
Przegaliński, E., Siwanowicz, J., Nowak, E., Papla, I., & Filip, M. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01079-2 · Cited by 38 · see citing works
Szumlinski, K. K., Frys, K. A., & Kalivas, P. W. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300473 · Cited by 36 · see citing works
Ago, Y., Nakamura, S., Kajita, N., Uda, M., Hashimoto, H., Baba, A., & Matsuda, T. (2007) · Synapse · doi:10.1002/syn.20421 · Cited by 34 · see citing works
Self-citationKing, G. R., Xiong, Z. Z., & Ellinwood, E. H. (1998) · Psychopharmacology · doi:10.1007/s002130050508 · Cited by 33 · see citing works
Effects of osemozotan, ritanserin and azasetron on cocaine-induced behavioral sensitization in mice
Ago, Y., Nakamura, S., Hayashi, A., Itoh, S., Baba, A., & Matsuda, T. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.07.036 · Cited by 24 · see citing works
Self-citationSzumlinski, K. K., McCafferty, C. A., Maisonneuve, I. M., & Glick, S. D. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02424-0 · Cited by 19 · see citing works
Yoo, J., Cho, J.-H., Yu, H., Lee, K., Lee, B., Jeong, S. M., Nah, S.-Y., Kim, H., Lee, S., & Jang, C. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.04137.x · Cited by 17 · see citing works
Muntasir, H. A., Rashid, M., Komiyama, T., Kawakami, J., & Nagatomo, T. (2006) · Journal of Pharmacological Sciences · doi:10.1254/jphs.fp0060171 · Cited by 13 · see citing works
Tanaka, T., Ishigooka, J., Watanabe, S., Nagata, E., & Miura, S. (1998) · PubMed · Cited by 9 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Auclair A, Drouin C, Cotecchia S, Glowinski J, Tassin JP. 5- HT2A and α1b-adrenergic receptors entirely mediate dopamine release, locomotor response and behavioral sensitization to opiates and psychostimulants. Eur J Neurosci. 2004;20:3073- 3084.
Cited by
Sorted by citations
Filip, M., Alenina, N. V., Bäder, M., & Przegaliński, E. (2010) · Addiction Biology · doi:10.1111/j.1369-1600.2010.00214.x · Cited by 91 · see citing works
Matsumoto, S., Yoshida, T., Murata, H., Harada, S., Fujita, N., Nakamura, S., Yamamoto, Y., Watanabe, T., Yonekura, H., Yamamoto, H., et al. (2008) · Biochemistry · doi:10.1021/bi800910v · Cited by 89 · see citing works
Self-citationThe Role of 5-HT3 Receptors in Drug Abuse and as a Target for Pharmacotherapy
Engleman, E., Rodd, Z. A., Bell, R. L., & Murphy, J. (2008) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152708786927886 · Cited by 88 · see citing works
New Insight into the Therapeutic Role of 5-HT1A Receptors in Central Nervous System Disorders
Ohno, Y. (2010) · Central Nervous System Agents in Medicinal Chemistry · doi:10.2174/187152410791196341 · Cited by 58 · see citing works
Effects of cocaine on the hypothalamic–pituitary–adrenal axis
Manetti, L., Cavagnini, F., Martino, E., & Ambrogio, A. G. (2014) · Journal of Endocrinological Investigation · doi:10.1007/s40618-014-0091-8 · Cited by 50 · see citing works
Mirtazapine protects against cisplatin‐induced oxidative stress and DNA damage in the rat brain
Güleç, M., Oral, E., Dursun, O. B., Yücel, A., Hacımüftüoğlu, A., Akçay, F., & Süleyman, H. (2012) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2012.02395.x · Cited by 43 · see citing works
Kaushal, N., Robson, M. J., Vinnakota, H., Narayanan, S., Avery, B. A., McCurdy, C. R., & Matsumoto, R. R. (2011) · The AAPS Journal · doi:10.1208/s12248-011-9274-9 · Cited by 37 · see citing works
Ohno, Y., Sofue, N., Imaoku, T., Morishita, E., Kumafuji, K., Sasa, M., & Serikawa, T. (2010) · Journal of Pharmacological Sciences · doi:10.1254/jphs.10156fp · Cited by 33 · see citing works
Attenuation of apomorphine-induced sensitization by buspirone
Ikram, H., & Haleem, D. J. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.04.007 · Cited by 31 · see citing works
The Adverse Effects of Prenatal METH Exposure on the Offspring: A Review
Li, J.-H., Liu, J.-L., Zhang, K.-K., Chen, L., Xu, J., & Xie, X. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.715176 · Cited by 31 · see citing works
Isingrini, E., Perret, L. C., Rainer, Q., Sagueby, S., Moquin, L., Gratton, A. P., & Bruno Giros, A. (2016) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.150028 · Cited by 27 · see citing works
Neuropharmacologic Studies on the Brain Serotonin1A Receptor Using the Selective Agonist Osemozotan
Matsuda, T. (2013) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.b13-00645 · Cited by 25 · see citing works
Self-citationAripiprazole attenuates established behavioral sensitization induced by methamphetamine
Futamura, T., Akiyama, S., Sugino, H., Forbes, A., McQuade, R. D., & Kikuchi, T. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.06.006 · Cited by 24 · see citing works
Tang, B., & Dafny, N. (2013) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2013.06.004 · Cited by 19 · see citing works
Jaehne, E. J., Ameti, D., Paiva, T., & van den Buuse, M. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00061 · Cited by 18 · see citing works
Treatment of the Psychostimulant-Sensitized Animal Model of Schizophrenia
Shuto, T., & Nishi, A. (2010) · CNS Neuroscience & Therapeutics · doi:10.1111/j.1755-5949.2010.00218.x · Cited by 16 · see citing works
Mizuno, M., Kawamura, H., Ishizuka, Y., Sotoyama, H., & Nawa, H. (2010) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2010.09.009 · Cited by 16 · see citing works
Sensitization to the Prosocial Effects of 3,4-Methylenedioxymethamphetamine (MDMA)
Curry, D. W., Berro, L. F., Belkoff, A. R., Sulima, A., Rice, K. C., & Howell, L. L. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.03.017 · Cited by 13 · see citing works
Tanaka, T., Ago, Y., Umehara, C., Imoto, E., Hasebe, S., Hashimoto, H., Takuma, K., & Matsuda, T. (2016) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyw115 · Cited by 13 · see citing works
Self-citationNagayasu, K., Kitaichi, M., Shirakawa, H., Nakagawa, T., & Kaneko, S. (2010) · Journal of Pharmacological Sciences · doi:10.1254/jphs.10075sc · Cited by 13 · see citing works
Der-Ghazarian, T. S., Call, T., Scott, S. N., Dai, K., Brunwasser, S. J., Noudali, S. N., Pentkowski, N. S., & Neisewander, J. L. (2017) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2017.00073 · Cited by 12 · see citing works
Echeverry‐Alzate, V., Tuda-Arízcun, M., Bühler, K., Santos, Á., Giné, E., Olmos, P., Gorriti, M. Á., Huertas, E., de Fonseca, F. R., & López‐Moreno, J. A. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.06.010 · Cited by 12 · see citing works
Igari, M., Shen, H., Hagino, Y., Fukushima, S., Kasahara, Y., Lesch, K., Murphy, D. L., Hall, F. S., Uhl, G. R., Ikeda, K., et al. (2014) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000120 · Cited by 12 · see citing works
Luoma, J., & Lear, M. K. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.733893 · Cited by 11 · see citing works
Teodorov, E., Camarini, R., Bernardi, M. M., & Felício, L. F. (2014) · Life Sciences · doi:10.1016/j.lfs.2014.03.021 · Cited by 11 · see citing works
Tsuchida, R., Kubo, M., Kuroda, M., Shibasaki, Y., Shintani, N., Abe, M., Köves, K., Hashimoto, H., & Baba, A. (2009) · Journal of Pharmacological Sciences · doi:10.1254/jphs.08297fp · Cited by 10 · see citing works
Self-citationTsuchida, R., Kubo, M., Shintani, N., Abe, M., Köves, K., Uetsuki, K., Kuroda, M., Hashimoto, H., & Baba, A. (2009) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.32.728 · Cited by 9 · see citing works
Self-citationOuk, K., Aungier, J., Cuesta, M., & Morton, A. J. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.12.033 · Cited by 7 · see citing works
Basmadjian, O. M., Occhieppo, V. B., Montemerlo, A., Rivas, G. A., Rubianes, M. D., Baiardi, G., & Bregonzio, C. (2024) · European Journal of Neuroscience · doi:10.1111/ejn.16312 · Cited by 6 · see citing works
Ishihara, K., Takahashi, N., Komoto, N., Yoshikawa, C., Fukumoto, S., Ide, S., Kimura, T., & Ozawa, K. (2013) · Journal of Pharmacological Sciences · doi:10.1254/jphs.13100fp · Cited by 4 · see citing works
Suppiramaniam, V. D., Bloemer, J., Reed, M. N., & Bhattacharya, S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.65382-5 · Cited by 4 · see citing works
Asth, L., Iglesias, L. P., Briânis, R. C., Marçal, A. P., Soares, N. P., de Aguiar, D. C., & Moreira, F. A. (2021) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-021-02053-x · Cited by 3 · see citing works
Moriya, Y., Kasahara, Y., Ishihara, K., Hall, F. S., Hagino, Y., Hen, R., Ikeda, K., Uhl, G. R., & Sora, I. (2023) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000745 · Cited by 2 · see citing works
Zoubaa, S., Konrad, R., Piontek, G., & Schlegel, J. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.01.070 · Cited by 2 · see citing works
Methamphetamine-Induced Hyperlocomotion
Ago, Y., Takuma, K., & Matsuda, T. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800212-4.00031-5 · Cited by 2 · see citing works
Self-citation(2014) · Receptors & Clinical Investigation · doi:10.14800/rci.103 · Cited by 2 · see citing works
Methamphetamine psychosis, the efficacy of atypical antipsychotics
Ardanı, A. R., & Nasab, A. M. (2014) · DOAJ (DOAJ: Directory of Open Access Journals) · doi:10.17463/rcm.2015.01.003 · Cited by 2 · see citing works
Similarities and differences in the effect of cocaine on α-adrenergic and muscarinic response
Manukhin, B. N., Berdysheva, L. V., Бойко, О. В., & Нестерова, Л. А. (2011) · Biology Bulletin · doi:10.1134/s1062359011030083 · Cited by 1 · see citing works
Molecular Mechanisms of Drug Abuse, Dependency and Craving
Wilcox, R. E. (2016) · Journal of Addiction and Dependence · doi:10.15436/2471-061x.16.006 · Cited by 1 · see citing works
Suppiramaniam, V. D., Abdel‐Rahman, E. A., & Parameshwaran, K. (2010) · Elsevier eBooks · doi:10.1016/b978-0-08-046884-6.01309-9 · Cited by 1 · see citing works
Psychopharmacological Studies in Mice
Matsuda, T. (2016) · YAKUGAKU ZASSHI · doi:10.1248/yakushi.15-00282
Self-citationRudberg, K. N. (2016) · CSUSB ScholarWorks (California State University, San Bernardino)
(2009) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e32832ae253
- Authors
- Ago, Y., Nakamura, S., Baba, A., & Matsuda, T.
- Affiliations
- The University of Osaka (JP)
- ORCID
- Ago, Yukio
- Venue
- Journal of Pharmacological Sciences
- Publisher
- Japanese Pharmacological Society
- Published
- 2008
- Volume
- 106
- Issue
- 1
- Pages
- 15-21
- ISSN
- 1347-8613 (ISSN-L)
- 1347-8648
- OpenAlex
- W2008362610
- Cited by
- 44
- References
- 47
- Citations by year
- 2024: 1 · 2023: 1 · 2021: 3 · 2019: 1 · 2017: 4 · 2016: 6 · 2014: 5 · 2013: 3 · 2012: 2
- FWCI
- 0.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of Pharmacological Sciences (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- serotonergic system, behavioral sensitization, methamphetamine, cocaine, psychostimulants, 5-HT1A receptor agonist, 5-HT2 receptor antagonist, ritanserin, 5-HT3 receptor antagonists, azasetron, serotonin release, prefrontal cortex, locomotor activity, addiction treatment, psychosis
- MeSH terms
- Central Nervous System Stimulants, Animals, Behavior, Animal, Brain, Cocaine, Dioxanes, Dioxoles, Disease Models, Animal, Ligands, Methamphetamine, Motor Activity, Oxazines, Receptors, Serotonin, Serotonin, Serotonin Antagonists, Ritanserin, Serotonin Receptor Agonists, Serotonin Agents, Bridged Bicyclo Compounds, Heterocyclic, Amphetamine-Related Disorders, Cocaine-Related Disorders, Mice, Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT3 Receptor Antagonists
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review