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Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy
Abstract
Our objective was to determine the level of adherence and reasons for non-adherence to antiretroviral therapy (ART) among HIV-positive (HIV+) people on ART in a resource-limited setting. Patients receiving ART were recruited into the cross-sectional study from three treatment centres in Kampala, Uganda. The number of missed doses over the last three days was assessed by structured patient interviews and dichotomized at ±95% adherence. Reasons for non-adherence were assessed with both structured patient interviews and unstructured qualitative interviews. Independent predictors of non-adherence were assessed with multivariate logistic regression. In all, 304 HIV-infected persons on ART were enrolled into the study. Factors associated with non-adherence were marital status (odds ratio (OR) = 2.93, 95% confidence interval (CI) 1.32–6.50) and low monthly income <50 US$ [OR = 2.77, 95% CI 1.64–4.67]. We concluded that levels of self-reported adherence in patients receiving ART in Kampala are comparable to levels in resource-rich settings with inability to purchase and secure a stable supply as a major barrier to adherence.
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Citations
Cited by
Adherence to Antiretroviral Therapy in Sub-Saharan Africa and North America: A Meta-analysis
Mills, E. J., Nachega, J. B., Buchan, I., Orbinski, J., Attaran, A., Singh, S., Rachlis, B., Wu, P., Cooper, C., Thabane, L., et al. (2006) · JAMA · doi:10.1001/jama.296.6.679 · Cited by 899
Self-citationMills, E. J., Nachega, J. B., Bangsberg, D. R., Singh, S., Rachlis, B., Wu, P., Wilson, K., Buchan, I., Gill, C. J., & Cooper, C. (2006) · PLoS Medicine · doi:10.1371/journal.pmed.0030438 · Cited by 818
Self-citationExplaining Adherence Success in Sub-Saharan Africa: An Ethnographic Study
Ware, N. C., Idoko, J., Kaaya, S., Biraro, I. A., Wyatt, M. A., Agbaji, O., Chalamilla, G., & Bangsberg, D. R. (2009) · PLoS Medicine · doi:10.1371/journal.pmed.1000011 · Cited by 437
Self-citationHeestermans, T., Browne, J. L., Aitken, S. C., Vervoort, S. C., & Klipstein-Grobusch, K. (2016) · BMJ Global Health · doi:10.1136/bmjgh-2016-000125 · Cited by 348
Metadata
- Authors
- Byakika-Tusiime, J., Oyugi, J. H., Tumwikirize, W. A., Katabira, E. T., Mugyenyi, P. N., & Bangsberg, D. R.
- Venue
- International Journal of STD & AIDS
- Publisher
- SAGE Publications
- Published
- 2005-01-01
- Volume
- 16
- Issue
- 1
- Pages
- 38-41
- ISSN
- 0956-4624 (ISSN-L)
- 1758-1052
- OpenAlex
- W2012840428
- Cited by
- 199
- References
- 0
- FWCI
- 8.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- Byakika-Tusiime, J., Oyugi, J. H., Tumwikirize, W. A., Katabira, E. T., Mugyenyi, P. N., & Bangsberg, D. R. (2005). Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy. International Journal of STD & AIDS. https://doi.org/10.1258/0956462052932548
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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