MRI to differentiate benign from malignant soft-tissue tumours of the extremities: a simplified systematic imaging approach using depth, size and heterogeneity of signal intensity
Open accessAbstract
Objective Differentiating between malignant and benign lesions on the basis of MR images depends on the experience of the radiologist. For non-experts, we aimed to develop a simplified systematic MRI approach that uses depth, size and heterogeneity on T(2) weighted MR images (T(2)WI) to differentiate between malignant and benign lesions, and evaluated its diagnostic accuracy. Methods MR images of 266 patients with histologically proven soft-tissue tumours of the extremities (102 malignant, 164 benign) were analysed according to depth (superficial or deep), size ( Results Univariate analysis showed that depth, size and heterogeneity on T(2)WI differed significantly between benign and malignant masses (p Conclusion A simplified systematic imaging approach, in the order signal intensity, size and depth, would be a reference to distinguish between benign and malignant soft-tissue tumours for non-experts.
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MRI is a medical imaging modality that allows for the evaluation of soft-tissue diseases and the assessment of bone quality.
“Magnetic Resonance Imaging (MRI) is a medical imaging modality that allows for the evaluation of soft-tissue diseases and the assessment of bone quality.”
From Towards 2D/3D Registration of the Preoperative MRI to Intraoperative Fluoroscopic Images for Visualisation of Bone Defects (2023) · cites this paper as Chung et al. 2012
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Ku, P.-C., Martin-Gomez, A., Gao, C., Grupp, R., Mears, S. C., & Armand, M. (2023) · Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization · doi:10.1080/21681163.2022.2152375 · Cited by 8 · see citing works
“This property has made MRI a good candidate for the evaluation of soft-tissue diseases, the assessment of bone quality, and the detection of bone tumours and tumour-like lesions (Chung et al. 2012; Nascimento et al. 2014; Chang et al. 2017).”
Background
- Authors
- Chung, W. J., Chung, H. W., Shin, M. J., Lee, S. H., Lee, M. H., Lee, J. S., Kim, M.-J., & Lee, W. K.
- Affiliations
- Asan Medical Center (KR)
- Kyungpook National University (KR)
- Venue
- The British Journal of Radiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-10
- Volume
- 85
- Issue
- 1018
- Pages
- e831-e836
- ISSN
- 0007-1285 (ISSN-L)
- 1748-880X
- PMC
- PMC3474004
- OpenAlex
- W2163372887
- Cited by
- 114
- References
- 0
- Citations by year
- 2026: 10 · 2025: 15 · 2024: 9 · 2023: 12 · 2022: 16 · 2021: 5 · 2020: 11 · 2019: 8 · 2018: 8 · 2017: 12 · 2016: 4 · 2015: 3 · 2014: 1
- FWCI
- 1.03
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- British Journal of Radiology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Sarcoma Diagnosis and Treatment
- Health Sciences › Medicine › Pathology and Forensic Medicine › Soft tissue tumors and treatment
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › MRI in cancer diagnosis
- Keywords
- soft tissue tumor, extremities, benign versus malignant differentiation, T2-weighted MRI, tumor size, depth of invasion, diagnostic accuracy
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Diagnosis, Differential, Extremities, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Regression Analysis, Retrospective Studies, Sarcoma, Sensitivity and Specificity, Soft Tissue Neoplasms, Tumor Burden, Young Adult
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