The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
A guide to ions and RNA structure
Open accessAbstract
RNA folding into stable tertiary structures is remarkably sensitive to the concentrations and types of cations present; an understanding of the physical basis of ion-RNA interactions is therefore a prerequisite for a quantitative accounting of RNA stability. This article summarizes the energetic factors that must be considered when ions interact with two different RNA environments. “Diffuse ions” accumulate near the RNA because of the RNA electrostatic field and remain largely hydrated. A “chelated” ion directly contacts a specific location on the RNA surface and is held in place by electrostatic forces. Energetic costs of ion chelation include displacement of some of the waters of hydration by the RNA surface and repulsion of diffuse ions. Methods are discussed for computing both the free energy of the set of diffuse ions associated with an RNA and the binding free energies of individual chelated ions. Such calculations quantitatively account for the effects of Mg 2+ on RNA stability where experimental data are available. An important conclusion is that diffuse ions are a major factor in the stabilization of RNA tertiary structures.
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The catalytic diversity of RNAs
Fedor, M. J., & Williamson, J. R. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1647 · Cited by 358
Predicting Stability of DNA Duplexes in Solutions Containing Magnesium and Monovalent Cations
Owczarzy, R., Moreira, B. G., You, Y., Behlke, M. A., & Walder, J. A. (2008) · Biochemistry · doi:10.1021/bi702363u · Cited by 363
Darnell, J. C., Fraser, C. E., Mostovetsky, O., Stefani, G., Jones, T. A., Eddy, S. R., & Darnell, R. B. (2005) · Genes & Development · doi:10.1101/gad.1276805 · Cited by 287
Martini coarse-grained force field: Extension to RNA
Uusitalo, J. J., Ingólfsson, H. I., Marrink, S. J., & Faustino, I. (2017) · Biophysical Journal · doi:10.1016/j.bpj.2017.05.043 · Cited by 259
Metadata
- Authors
- DRAPER, D. E.
- Venue
- RNA
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2004-02-17
- Volume
- 10
- Issue
- 3
- Pages
- 335-343
- ISSN
- 1355-8382 (ISSN-L)
- 1469-9001
- OpenAlex
- W2132976721
- Cited by
- 608
- References
- 37
- FWCI
- 8.09
- Type
- journal article
- Language
- en
- Open access
- bronze
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