The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Differentiation and Elimination of Uterine Natural Killer Cells in Delayed Implantation and Parturition Mice
Open accessAbstract
To clarify the roles of uterine natural killer (uNK) cells in implantation and parturition, differentiation and elimination of uNK cells in the pregnant uterus was examined using artificial delayed implantation (DI) and delayed parturition (DP) mice. To prepare DI mice, pregnant mice were ovariectomized on the third day of pregnancy (D3) and treated with 2 mg progesterone daily. The same amount of progesterone was administered on D15 or D17 of normal pregnant mice at 24 h intervals until sampling to prepare DP mice. The uNK cells contained PAS-positive granules on D8 in DI mice. The uNK cells in DI mice were smaller in size, and differentiation of these cells was delayed compared to those of the control mice. From D19 to D21 in DP mice, the metrial gland was well developed and uNK cells were present. The number of uNK cell granules decreased on D21, and there were no uNK cells in the normal pregnant mice. This result suggests that differentiation of uNK cells is not directly related to implantation, but elimination of these cells is closely involved in parturition.
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“Multiple factors initiate parturition, including fetal cortisol, maternal drop in progesterone, oxytocin, prostaglandin F2α and other endocrine factors56–59.”
From Conditional loss of ERK1 and ERK2 results in abnormal placentation and delayed parturition in the mouse (2019) · cites this paper as [59]
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Cites
Endocrine control of parturition
Thorburn, G. D., & Challis, J. R. G. (1979) · Physiological Reviews · doi:10.1152/physrev.1979.59.4.863 · Cited by 426
Dosiou, C., & Giudice, L. C. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0021 · Cited by 394
Granulated Metrial Gland Cells
Peel, S. (1989) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-642-74170-8 · Cited by 206
Delgado, S. R., McBey, B.-A., Yamashiro, S., et al. (1996) · Journal of Leukocyte Biology · doi:10.1002/jlb.59.2.262 · Cited by 104
Granulated metrial gland cells: A natural killer cell subset of the pregnant murine uterus
Croy, B. A., & Kiso, Y. (1993) · Microscopy Research and Technique · doi:10.1002/jemt.1070250302 · Cited by 92
Self-citationvan den Heuvel, M., McBey, B.-A., Hahnel, A. C., & Croy, B. A. (1996) · Journal of Reproductive Immunology · doi:10.1016/0165-0378(96)00966-7 · Cited by 39
Granulated metrial gland cells in the virgin and early pregnant mouse uterus.
Stewart, I. J., & Peel, S. E. (1981) · PubMed · Cited by 28
Kusakabe, K. T., Okada, T., Sasaki, F., et al. (1999) · Journal of Veterinary Medical Science · doi:10.1292/jvms.61.1093 · Cited by 27
Metrial gland cells in deciduomata of pseudopregnancy.
Peel, S. E., Stewart, I. J., & Bulmer, D. C. (1979) · PubMed · Cited by 22
Stewart, I. J., & Peel, S. E. (1982) · PubMed · Cited by 12
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Brown, J. L., Sones, J. L., Angulo, C. N., Abbott, K., Miller, A. D., Boehm, U., & Roberson, M. S. (2019) · Scientific Reports · doi:10.1038/s41598-019-45997-0 · Cited by 13
Metadata
- Authors
- KOKUBU, K., HONDO, E., SAKAGUCHI, N., SAGARA, E., & KISO, Y.
- Affiliations
- Yamaguchi University (JP)
- Kyushu Dental University (JP)
- ORCID
- HONDO, Eiichi
- Venue
- Journal of Reproduction and Development
- Published
- 2005
- Volume
- 51
- Issue
- 6
- Pages
- 773-776
- ISSN
- 0916-8818 (ISSN-L)
- 1348-4400
- OpenAlex
- W2006038795
- Cited by
- 16
- References
- 10
- Citations by year
- 2023: 2 · 2019: 1 · 2018: 1 · 2017: 2 · 2016: 2 · 2014: 2 · 2013: 2 · 2012: 2
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- Journal of Reproduction and Development (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Life Sciences › Immunology and Microbiology › Immunology › Immune Cell Function and Interaction
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Keywords
- uterine natural killer cells, delayed implantation, delayed parturition, metrial gland, progesterone, ovariectomy, PAS-positive granules, pregnancy, implantation, childbirth
- MeSH terms
- Animals, Cell Count, Cell Differentiation, Female, Killer Cells, Natural, Male, Metrial Gland, Mice, Inbred ICR, Embryo Implantation, Pregnancy, Uterus, Parturition, Mice
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- The paper
- KOKUBU, K., HONDO, E., SAKAGUCHI, N., SAGARA, E., & KISO, Y. (2005). Differentiation and Elimination of Uterine Natural Killer Cells in Delayed Implantation and Parturition Mice. Journal of Reproduction and Development. https://doi.org/10.1262/jrd.17033
